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Antepartum hemorrhage

MedGen UID:
542157
Concept ID:
C0269608
Pathologic Function
Synonyms: Antepartum haemorrhage; Antepartum Hemorrhage; APH - Antepartum hemorrhage; Prepartum haemorrhage; Prepartum hemorrhage
SNOMED CT: APH - Antepartum hemorrhage (34842007); Antepartum hemorrhage (34842007)
 
HPO: HP:0025328

Definition

Significant maternal hemorrhage/bleed in the second half of pregnancy and prior to the birth of the baby. [from HPO]

Professional guidelines

PubMed

Jain V, Gagnon R
J Obstet Gynaecol Can 2023 Jul;45(7):506-518. Epub 2023 May 18 doi: 10.1016/j.jogc.2023.05.009. PMID: 37209787
Freeman SW, Denoble A, Kuller JA, Ellestad S, Dotters-Katz S
Obstet Gynecol Surv 2022 May;77(5):283-292. doi: 10.1097/OGX.0000000000001024. PMID: 35522430
Jain V, Bos H, Bujold E
J Obstet Gynaecol Can 2020 Jul;42(7):906-917.e1. doi: 10.1016/j.jogc.2019.07.019. PMID: 32591150

Recent clinical studies

Etiology

Corbetta-Rastelli CM, Friedman AM, Sobhani NC, Arditi B, Goffman D, Wen T
Obstet Gynecol 2023 Jan 1;141(1):152-161. Epub 2022 Nov 30 doi: 10.1097/AOG.0000000000004972. PMID: 36701615
Jain V, Bos H, Bujold E
J Obstet Gynaecol Can 2020 Jul;42(7):906-917.e1. doi: 10.1016/j.jogc.2019.07.019. PMID: 32591150
Mantel Ä, Hirschberg AL, Stephansson O
JAMA Psychiatry 2020 Mar 1;77(3):285-293. doi: 10.1001/jamapsychiatry.2019.3664. PMID: 31746972Free PMC Article
Roberge S, Bujold E, Nicolaides KH
Am J Obstet Gynecol 2018 May;218(5):483-489. Epub 2018 Jan 3 doi: 10.1016/j.ajog.2017.12.238. PMID: 29305829
Wang C, Geng H, Liu W, Zhang G
Medicine (Baltimore) 2017 May;96(18):e6696. doi: 10.1097/MD.0000000000006696. PMID: 28471964Free PMC Article

Diagnosis

Villani LA, Pavalagantharajah S, D'Souza R
Am J Obstet Gynecol MFM 2020 Aug;2(3):100116. Epub 2020 Apr 16 doi: 10.1016/j.ajogmf.2020.100116. PMID: 33345867
Jain V, Bos H, Bujold E
J Obstet Gynaecol Can 2020 Jul;42(7):906-917.e1. doi: 10.1016/j.jogc.2019.07.019. PMID: 32591150
Mantel Ä, Hirschberg AL, Stephansson O
JAMA Psychiatry 2020 Mar 1;77(3):285-293. doi: 10.1001/jamapsychiatry.2019.3664. PMID: 31746972Free PMC Article
Fan D, Wu S, Liu L, Xia Q, Wang W, Guo X, Liu Z
Sci Rep 2017 Jan 9;7:40320. doi: 10.1038/srep40320. PMID: 28067303Free PMC Article
MacMullen NJ, Dulski LA, Meagher B
MCN Am J Matern Child Nurs 2005 Jan-Feb;30(1):46-51. PMID: 15622149

Therapy

Corbetta-Rastelli CM, Friedman AM, Sobhani NC, Arditi B, Goffman D, Wen T
Obstet Gynecol 2023 Jan 1;141(1):152-161. Epub 2022 Nov 30 doi: 10.1097/AOG.0000000000004972. PMID: 36701615
Freeman SW, Denoble A, Kuller JA, Ellestad S, Dotters-Katz S
Obstet Gynecol Surv 2022 May;77(5):283-292. doi: 10.1097/OGX.0000000000001024. PMID: 35522430
Roberge S, Bujold E, Nicolaides KH
Am J Obstet Gynecol 2018 May;218(5):483-489. Epub 2018 Jan 3 doi: 10.1016/j.ajog.2017.12.238. PMID: 29305829
Wang C, Geng H, Liu W, Zhang G
Medicine (Baltimore) 2017 May;96(18):e6696. doi: 10.1097/MD.0000000000006696. PMID: 28471964Free PMC Article
Fan D, Wu S, Liu L, Xia Q, Wang W, Guo X, Liu Z
Sci Rep 2017 Jan 9;7:40320. doi: 10.1038/srep40320. PMID: 28067303Free PMC Article

Prognosis

Klinger G, Bromiker R, Zaslavsky-Paltiel I, Sokolover N, Lerner-Geva L, Yogev Y, Reichman B; Israel Neonatal Network
Am J Perinatol 2021 Sep;38(11):1134-1141. Epub 2020 May 23 doi: 10.1055/s-0040-1710353. PMID: 32446258
Altraigey A, Ellaithy M, Barakat E, Majeed A
J Matern Fetal Neonatal Med 2021 Jul;34(13):2124-2131. Epub 2019 Sep 5 doi: 10.1080/14767058.2019.1659239. PMID: 31434519
Khanam R, Ahmed S, Creanga AA, Begum N, Koffi AK, Mahmud A, Rosen H, Baqui AH; Projahnmo Study Group in Bangladesh
BMC Pregnancy Childbirth 2017 Mar 7;17(1):81. doi: 10.1186/s12884-017-1264-1. PMID: 28270117Free PMC Article
Rocha Filho EA, Costa ML, Cecatti JG, Parpinelli MA, Haddad SM, Sousa MH, Melo EF Jr, Surita FG, Souza JP; Brazilian Network for Surveillance of Severe Maternal Morbidity Study Group
Acta Obstet Gynecol Scand 2015 Jan;94(1):50-8. Epub 2014 Nov 11 doi: 10.1111/aogs.12529. PMID: 25327163
Magann EF, Cummings JE, Niederhauser A, Rodriguez-Thompson D, McCormack R, Chauhan SP
Obstet Gynecol Surv 2005 Nov;60(11):741-5. doi: 10.1097/01.ogx.0000182881.53139.f7. PMID: 16250922

Clinical prediction guides

Yadav V, Sharma JB, Kriplani A, Bhatla N, Kachhawa G, Mahey R, Kumari R
Indian J Tuberc 2022 Jul;69(3):305-310. Epub 2021 Jan 7 doi: 10.1016/j.ijtb.2020.12.006. PMID: 35760479
Racher ML, Morris M, Scott AP, Ounpraseuth ST, Hu Z, Whittington JR, Quick CM, Magann EF
Arch Gynecol Obstet 2022 May;305(5):1265-1277. Epub 2021 Sep 29 doi: 10.1007/s00404-021-06253-x. PMID: 34590170
Mantel Ä, Hirschberg AL, Stephansson O
JAMA Psychiatry 2020 Mar 1;77(3):285-293. doi: 10.1001/jamapsychiatry.2019.3664. PMID: 31746972Free PMC Article
Lalani S, Choudhry AJ, Firth B, Bacal V, Walker M, Wen SW, Singh S, Amath A, Hodge M, Chen I
Hum Reprod 2018 Oct 1;33(10):1854-1865. doi: 10.1093/humrep/dey269. PMID: 30239732Free PMC Article
Wang C, Geng H, Liu W, Zhang G
Medicine (Baltimore) 2017 May;96(18):e6696. doi: 10.1097/MD.0000000000006696. PMID: 28471964Free PMC Article

Recent systematic reviews

Tang W, Zhou LJ, Zhang WQ, Jia YJ, Hu FH, Chen HL
Schizophr Res 2023 Dec;262:156-167. Epub 2023 Nov 16 doi: 10.1016/j.schres.2023.11.001. PMID: 37979419
Lalani S, Choudhry AJ, Firth B, Bacal V, Walker M, Wen SW, Singh S, Amath A, Hodge M, Chen I
Hum Reprod 2018 Oct 1;33(10):1854-1865. doi: 10.1093/humrep/dey269. PMID: 30239732Free PMC Article
Roberge S, Bujold E, Nicolaides KH
Am J Obstet Gynecol 2018 May;218(5):483-489. Epub 2018 Jan 3 doi: 10.1016/j.ajog.2017.12.238. PMID: 29305829
Fan D, Wu S, Liu L, Xia Q, Wang W, Guo X, Liu Z
Sci Rep 2017 Jan 9;7:40320. doi: 10.1038/srep40320. PMID: 28067303Free PMC Article
Maheshwari A, Pandey S, Shetty A, Hamilton M, Bhattacharya S
Fertil Steril 2012 Aug;98(2):368-77.e1-9. Epub 2012 Jun 13 doi: 10.1016/j.fertnstert.2012.05.019. PMID: 22698643

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