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Acquired factor X deficiency

MedGen UID:
543977
Concept ID:
C0272328
Disease or Syndrome
Synonyms: Acquired factor 10 deficiency; Acquired Factor X Deficiency; acquired factor X deficiency; Acquired factor X deficiency disease; Acquired Stuart factor deficiency disease; aFX
SNOMED CT: Acquired factor X deficiency (33820001); Acquired factor 10 deficiency (33820001); Acquired factor X deficiency disease (33820001); Acquired Stuart factor deficiency disease (33820001)
 
Monarch Initiative: MONDO:0021134
Orphanet: ORPHA599501

Definition

An acquired coagulation disorder characterized by the partial or complete absence of factor X activity in the blood. [from NCI]

Professional guidelines

PubMed

Mahmood S, Blundell J, Drebes A, Hawkins PN, Wechalekar AD
Blood 2014 May 1;123(18):2899-900. doi: 10.1182/blood-2014-02-556514. PMID: 24786460

Recent clinical studies

Etiology

Dejhansathit S, Suvannasankha A
J Investig Med High Impact Case Rep 2019 Jan-Dec;7:2324709619832332. doi: 10.1177/2324709619832332. PMID: 30947547Free PMC Article
Cordes S, Gertz MA, Buadi FK, Lin Y, Lacy MQ, Kapoor P, Kumar SK, McCurdy A, Dispenzieri A, Dingli D, Hayman SR, Hogan WJ, Pruthi RK
Blood Coagul Fibrinolysis 2016 Jan;27(1):101-8. doi: 10.1097/MBC.0000000000000367. PMID: 26218969
Lim MY, McCarthy T, Chen SL, Rollins-Raval MA, Ma AD
Eur J Haematol 2016 Jan;96(1):60-4. Epub 2015 May 18 doi: 10.1111/ejh.12548. PMID: 25782416
Kapoor P, Singh E, Radhakrishnan P, Mehta P
Am J Hematol 2006 Dec;81(12):946-54. doi: 10.1002/ajh.20736. PMID: 16937390
Uprichard J, Perry DJ
Blood Rev 2002 Jun;16(2):97-110. doi: 10.1054/blre.2002.0191. PMID: 12127953

Diagnosis

Coussee A, Alliet G, Hervent AS, Vynckier L, Emmerechts J, Van Hecke S, Persijn L
Acta Clin Belg 2023 Dec;78(6):524-528. Epub 2023 Oct 16 doi: 10.1080/17843286.2023.2265650. PMID: 37800976
Souri M, Osaki T, Shimura Y, Ichikawa S, Mori M, Ogawa Y, Ichinose A
Haemophilia 2023 Mar;29(2):555-563. Epub 2022 Dec 8 doi: 10.1111/hae.14711. PMID: 36478471
Reynolds SB, Maghavani DP, Hashmi H
BMJ Case Rep 2019 Sep 16;12(9) doi: 10.1136/bcr-2019-230249. PMID: 31527206Free PMC Article
Jia J, Wang H, Wu M, Zhang F, Liu X, Chen W, Liu A
Acta Haematol 2018;140(1):46-50. Epub 2018 Aug 16 doi: 10.1159/000491545. PMID: 30114681
Uprichard J, Perry DJ
Blood Rev 2002 Jun;16(2):97-110. doi: 10.1054/blre.2002.0191. PMID: 12127953

Therapy

Reynolds SB, Maghavani DP, Hashmi H
BMJ Case Rep 2019 Sep 16;12(9) doi: 10.1136/bcr-2019-230249. PMID: 31527206Free PMC Article
Dejhansathit S, Suvannasankha A
J Investig Med High Impact Case Rep 2019 Jan-Dec;7:2324709619832332. doi: 10.1177/2324709619832332. PMID: 30947547Free PMC Article
Patel G, Hari P, Szabo A, Rein L, Kreuziger LB, Chhabra S, Dhakal B, D'Souza A
Hematol Oncol Stem Cell Ther 2019 Mar;12(1):10-14. Epub 2018 Jun 28 doi: 10.1016/j.hemonc.2018.05.002. PMID: 30879471
Kapoor P, Singh E, Radhakrishnan P, Mehta P
Am J Hematol 2006 Dec;81(12):946-54. doi: 10.1002/ajh.20736. PMID: 16937390
Pabinger I, Bettelheim P, Dudczak R, Hinterberger W, Kyrle PA, Niessner H, Schwarzinger I, Speiser W, Lechner K
Ann Hematol 1991 May;62(5):174-9. doi: 10.1007/BF01703144. PMID: 2049464

Prognosis

Patel G, Hari P, Szabo A, Rein L, Kreuziger LB, Chhabra S, Dhakal B, D'Souza A
Hematol Oncol Stem Cell Ther 2019 Mar;12(1):10-14. Epub 2018 Jun 28 doi: 10.1016/j.hemonc.2018.05.002. PMID: 30879471
Iwadate D, Hasegawa E, Hoshino J, Hayami N, Sumida K, Yamanouchi M, Sekine A, Kawada M, Hiramatsu R, Suwabe T, Sawa N, Yuasa M, Wake A, Fujii T, Ohashi K, Takaichi K, Ubara Y
Intern Med 2018 Mar 1;57(5):701-706. Epub 2017 Nov 1 doi: 10.2169/internalmedicine.9263-17. PMID: 29093408Free PMC Article
Lim MY, McCarthy T, Chen SL, Rollins-Raval MA, Ma AD
Eur J Haematol 2016 Jan;96(1):60-4. Epub 2015 May 18 doi: 10.1111/ejh.12548. PMID: 25782416
Thompson CA, Kyle R, Gertz M, Heit J, Pruthi R, Pardanani A
Am J Hematol 2010 Mar;85(3):171-3. doi: 10.1002/ajh.21603. PMID: 20052750Free PMC Article
Emori Y, Sakugawa M, Niiya K, Kiguchi T, Kojima K, Takenaka K, Shinagawa K, Ishimaru F, Ikeda K, Tanimoto M, Yamasaki R, Ohara N, Harada M
Blood Coagul Fibrinolysis 2002 Sep;13(6):555-9. doi: 10.1097/00001721-200209000-00011. PMID: 12192308

Clinical prediction guides

Coussee A, Alliet G, Hervent AS, Vynckier L, Emmerechts J, Van Hecke S, Persijn L
Acta Clin Belg 2023 Dec;78(6):524-528. Epub 2023 Oct 16 doi: 10.1080/17843286.2023.2265650. PMID: 37800976
Arahata M, Takamatsu H, Morishita E, Kadohira Y, Yamada S, Ichinose A, Asakura H
Int J Hematol 2020 Apr;111(4):550-558. Epub 2020 Jan 3 doi: 10.1007/s12185-019-02811-x. PMID: 31897889
Patel G, Hari P, Szabo A, Rein L, Kreuziger LB, Chhabra S, Dhakal B, D'Souza A
Hematol Oncol Stem Cell Ther 2019 Mar;12(1):10-14. Epub 2018 Jun 28 doi: 10.1016/j.hemonc.2018.05.002. PMID: 30879471
Thompson CA, Kyle R, Gertz M, Heit J, Pruthi R, Pardanani A
Am J Hematol 2010 Mar;85(3):171-3. doi: 10.1002/ajh.21603. PMID: 20052750Free PMC Article
Pabinger I, Bettelheim P, Dudczak R, Hinterberger W, Kyrle PA, Niessner H, Schwarzinger I, Speiser W, Lechner K
Ann Hematol 1991 May;62(5):174-9. doi: 10.1007/BF01703144. PMID: 2049464

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