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Chronic glomerulonephritis

MedGen UID:
56293
•Concept ID:
C0152451
•
Disease or Syndrome
Synonyms: CGN - Chronic glomerulonephritis; Chronic Glomerulonephritis
SNOMED CT: CGN - Chronic glomerulonephritis (20917003); Chronic glomerulonephritis (20917003)

Definition

A chronic, persistent inflammation of the glomeruli, which is slowly progressive, leading to impaired kidney function. [from NCI]

Professional guidelines

PubMed

New and old approaches to nutritional management of acute and chronic glomerulonephritis.
Hanna RM, Ahdoot RS, Rhee CM, Tantisattamo E, Al Ammar F, Kalantar-Zadeh K
Curr Opin Nephrol Hypertens 2023 Jan 1;32(1):76-80. Epub 2022 Nov 21 doi: 10.1097/MNH.0000000000000855. PMID: 36444665
Mechanism of onset and exacerbation of chronic glomerulonephritis and its treatment.
Kawasaki Y
Pediatr Int 2011 Dec;53(6):795-806. Epub 2011 Nov 10 doi: 10.1111/j.1442-200X.2011.03469.x. PMID: 21902765
Treatment of IgA nephropathy.
Barratt J, Feehally J
Kidney Int 2006 Jun;69(11):1934-8. doi: 10.1038/sj.ki.5000419. PMID: 16641928

Recent clinical studies

Etiology

Proximity to petrochemical industrial parks and risk of chronic glomerulonephritis.
Chin WS, Pan SC, Huang CC, Chen YC, Hsu CY, Lin P, Chen PC, Guo YL
Environ Res 2022 May 15;208:112700. Epub 2022 Jan 10 doi: 10.1016/j.envres.2022.112700. PMID: 35016869
The role of podocytes dysfunction in chronic glomerulonephritis progression.
Chebotareva NV, Bobkova IN, Lysenko LV
Ter Arkh 2018 Jun 20;90(6):92-97. doi: 10.26442/terarkh201890692-97. PMID: 30701911
Kidneys in chronic liver diseases.
Hartleb M, Gutkowski K
World J Gastroenterol 2012 Jun 28;18(24):3035-49. doi: 10.3748/wjg.v18.i24.3035. PMID: 22791939Free PMC Article
CKD in MYH9-related disorders.
Singh N, Nainani N, Arora P, Venuto RC
Am J Kidney Dis 2009 Oct;54(4):732-40. Epub 2009 Sep 2 doi: 10.1053/j.ajkd.2009.06.023. PMID: 19726116
Treatment of IgA nephropathy.
Barratt J, Feehally J
Kidney Int 2006 Jun;69(11):1934-8. doi: 10.1038/sj.ki.5000419. PMID: 16641928

Diagnosis

Role of MCP-1 as an inflammatory biomarker in nephropathy.
Liu Y, Xu K, Xiang Y, Ma B, Li H, Li Y, Shi Y, Li S, Bai Y
Front Immunol 2023;14:1303076. Epub 2024 Jan 4 doi: 10.3389/fimmu.2023.1303076. PMID: 38239353Free PMC Article
The dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial: baseline characteristics.
Wheeler DC, Stefansson BV, Batiushin M, Bilchenko O, Cherney DZI, Chertow GM, Douthat W, Dwyer JP, Escudero E, Pecoits-Filho R, Furuland H, Górriz JL, Greene T, Haller H, Hou FF, Kang SW, Isidto R, Khullar D, Mark PB, McMurray JJV, Kashihara N, Nowicki M, Persson F, Correa-Rotter R, Rossing P, Toto RD, Umanath K, Van Bui P, Wittmann I, Lindberg M, Sjöström CD, Langkilde AM, Heerspink HJL
Nephrol Dial Transplant 2020 Oct 1;35(10):1700-1711. doi: 10.1093/ndt/gfaa234. PMID: 32862232Free PMC Article
Renal Involvement in Idiopathic Inflammatory Myopathies.
Cucchiari D, Angelini C
Clin Rev Allergy Immunol 2017 Feb;52(1):99-107. doi: 10.1007/s12016-015-8524-5. PMID: 26590948
Lipidomics: new insight into kidney disease.
Zhao YY, Vaziri ND, Lin RC
Adv Clin Chem 2015;68:153-75. Epub 2015 Jan 7 doi: 10.1016/bs.acc.2014.11.002. PMID: 25858872
CKD in MYH9-related disorders.
Singh N, Nainani N, Arora P, Venuto RC
Am J Kidney Dis 2009 Oct;54(4):732-40. Epub 2009 Sep 2 doi: 10.1053/j.ajkd.2009.06.023. PMID: 19726116

Therapy

Identification of novel therapeutic targets for chronic kidney disease and kidney function by integrating multi-omics proteome with transcriptome.
Si S, Liu H, Xu L, Zhan S
Genome Med 2024 Jun 19;16(1):84. doi: 10.1186/s13073-024-01356-x. PMID: 38898508Free PMC Article
Treatment strategy with multidrug therapy and tonsillectomy pulse therapy for childhood-onset severe IgA nephropathy.
Kawasaki Y
Clin Exp Nephrol 2022 Jun;26(6):501-511. Epub 2022 Feb 4 doi: 10.1007/s10157-022-02187-z. PMID: 35119558
Proximity to petrochemical industrial parks and risk of chronic glomerulonephritis.
Chin WS, Pan SC, Huang CC, Chen YC, Hsu CY, Lin P, Chen PC, Guo YL
Environ Res 2022 May 15;208:112700. Epub 2022 Jan 10 doi: 10.1016/j.envres.2022.112700. PMID: 35016869
The dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial: baseline characteristics.
Wheeler DC, Stefansson BV, Batiushin M, Bilchenko O, Cherney DZI, Chertow GM, Douthat W, Dwyer JP, Escudero E, Pecoits-Filho R, Furuland H, Górriz JL, Greene T, Haller H, Hou FF, Kang SW, Isidto R, Khullar D, Mark PB, McMurray JJV, Kashihara N, Nowicki M, Persson F, Correa-Rotter R, Rossing P, Toto RD, Umanath K, Van Bui P, Wittmann I, Lindberg M, Sjöström CD, Langkilde AM, Heerspink HJL
Nephrol Dial Transplant 2020 Oct 1;35(10):1700-1711. doi: 10.1093/ndt/gfaa234. PMID: 32862232Free PMC Article
Mechanism of onset and exacerbation of chronic glomerulonephritis and its treatment.
Kawasaki Y
Pediatr Int 2011 Dec;53(6):795-806. Epub 2011 Nov 10 doi: 10.1111/j.1442-200X.2011.03469.x. PMID: 21902765

Prognosis

Role of MCP-1 as an inflammatory biomarker in nephropathy.
Liu Y, Xu K, Xiang Y, Ma B, Li H, Li Y, Shi Y, Li S, Bai Y
Front Immunol 2023;14:1303076. Epub 2024 Jan 4 doi: 10.3389/fimmu.2023.1303076. PMID: 38239353Free PMC Article
The dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial: baseline characteristics.
Wheeler DC, Stefansson BV, Batiushin M, Bilchenko O, Cherney DZI, Chertow GM, Douthat W, Dwyer JP, Escudero E, Pecoits-Filho R, Furuland H, Górriz JL, Greene T, Haller H, Hou FF, Kang SW, Isidto R, Khullar D, Mark PB, McMurray JJV, Kashihara N, Nowicki M, Persson F, Correa-Rotter R, Rossing P, Toto RD, Umanath K, Van Bui P, Wittmann I, Lindberg M, Sjöström CD, Langkilde AM, Heerspink HJL
Nephrol Dial Transplant 2020 Oct 1;35(10):1700-1711. doi: 10.1093/ndt/gfaa234. PMID: 32862232Free PMC Article
Renal Involvement in Idiopathic Inflammatory Myopathies.
Cucchiari D, Angelini C
Clin Rev Allergy Immunol 2017 Feb;52(1):99-107. doi: 10.1007/s12016-015-8524-5. PMID: 26590948
Lipidomics: new insight into kidney disease.
Zhao YY, Vaziri ND, Lin RC
Adv Clin Chem 2015;68:153-75. Epub 2015 Jan 7 doi: 10.1016/bs.acc.2014.11.002. PMID: 25858872
Kidneys in chronic liver diseases.
Hartleb M, Gutkowski K
World J Gastroenterol 2012 Jun 28;18(24):3035-49. doi: 10.3748/wjg.v18.i24.3035. PMID: 22791939Free PMC Article

Clinical prediction guides

Role of MCP-1 as an inflammatory biomarker in nephropathy.
Liu Y, Xu K, Xiang Y, Ma B, Li H, Li Y, Shi Y, Li S, Bai Y
Front Immunol 2023;14:1303076. Epub 2024 Jan 4 doi: 10.3389/fimmu.2023.1303076. PMID: 38239353Free PMC Article
Intrarenal renin-angiotensin system activation and macrophage infiltrations in pediatric chronic glomerulonephritis.
Hattori T, Fujioka K, Nagai T, Kondo S, Kagami S, Hirayama M, Urushihara M
Pediatr Nephrol 2023 Nov;38(11):3711-3719. Epub 2023 May 25 doi: 10.1007/s00467-023-06026-5. PMID: 37231123Free PMC Article
Predictors of prognosis in IgA nephropathy.
Tomino Y
Kaohsiung J Med Sci 2012 Oct;28(10):517-20. Epub 2012 Sep 25 doi: 10.1016/j.kjms.2012.04.012. PMID: 23089315
Polyamines in renal failure.
Igarashi K, Ueda S, Yoshida K, Kashiwagi K
Amino Acids 2006 Nov;31(4):477-83. Epub 2006 Mar 24 doi: 10.1007/s00726-006-0264-7. PMID: 16554974
Renal osteodystrophy.
Wong LY, Wu CJ, Lin JC
Zhonghua Yi Xue Za Zhi (Taipei) 1991 May;47(5):342-9. PMID: 1649677

Recent systematic reviews

Meta-analysis of the effectiveness and safety of Shenyankangfu tablets combined with losartan potassium in the treatment of chronic glomerulonephritis.
Feng PF, Chen XF, Sheng N, Zhu LX
PLoS One 2022;17(10):e0275735. Epub 2022 Oct 10 doi: 10.1371/journal.pone.0275735. PMID: 36215266Free PMC Article
Association Between Telomere Length, Chronic Kidney Disease, and Renal Traits: A Systematic Review.
Ameh OI, Okpechi IG, Dandara C, Kengne AP
OMICS 2017 Mar;21(3):143-155. doi: 10.1089/omi.2016.0180. PMID: 28253088
Dialysis-treated end-stage kidney disease in Libya: epidemiology and risk factors.
Goleg FA, Kong NC, Sahathevan R
Int Urol Nephrol 2014 Aug;46(8):1581-7. Epub 2014 Mar 27 doi: 10.1007/s11255-014-0694-1. PMID: 24671275

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