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Lacrimal gland cancer

MedGen UID:
56315
•Concept ID:
C0153627
•
Neoplastic Process
Synonyms: cancer of lacrimal gland; lacrimal gland cancer; Malignant Lacrimal Gland Neoplasm; malignant lacrimal gland neoplasm; Malignant Lacrimal Gland Tumor; malignant lacrimal gland tumor; malignant lacrimal gland tumour; Malignant neoplasm of lacrimal gland; Malignant Neoplasm of Lacrimal Gland; malignant neoplasm of lacrimal gland; Malignant Neoplasm of the Lacrimal Gland; malignant neoplasm of the lacrimal gland; Malignant tumor of lacrimal gland; Malignant Tumor of Lacrimal Gland; malignant tumor of lacrimal gland; Malignant Tumor of the Lacrimal Gland; malignant tumor of the lacrimal gland; malignant tumour of lacrimal gland; malignant tumour of the lacrimal gland
SNOMED CT: Malignant neoplasm of lacrimal gland (188272000); Malignant tumor of lacrimal gland (188272000)
 
Monarch Initiative: MONDO:0002464

Definition

A primary or metastatic malignant neoplasm affecting the lacrimal gland. [from NCI]

Professional guidelines

PubMed

Clinical features and management of dacryops.
Ozgonul C, Uysal Y, Ayyildiz O, Kucukevcilioglu M
Orbit 2018 Aug;37(4):262-265. Epub 2018 Jan 4 doi: 10.1080/01676830.2017.1423081. PMID: 29300516
Evaluation and Management of Chemotherapy-Induced Epiphora, Punctal and Canalicular Stenosis, and Nasolacrimal Duct Obstruction.
Mansur C, Pfeiffer ML, Esmaeli B
Ophthalmic Plast Reconstr Surg 2017 Jan/Feb;33(1):9-12. doi: 10.1097/IOP.0000000000000745. PMID: 27429222
Current treatment of lacrimal gland carcinoma.
Woo KI, Kim YD, Sa HS, Esmaeli B
Curr Opin Ophthalmol 2016 Sep;27(5):449-56. doi: 10.1097/ICU.0000000000000301. PMID: 27273588

Recent clinical studies

Etiology

Outcomes in patients with lacrimal gland carcinoma treated with definitive radiotherapy or eye-sparing surgery followed by adjuvant radiotherapy.
Lin YH, Huang SM, Yap WK, Yang JW, Yeung L, Tsan DL, Chang JT, Chen LC
Radiat Oncol 2020 Jun 22;15(1):156. doi: 10.1186/s13014-020-01601-8. PMID: 32571366Free PMC Article
Epidemiological trends in malignant lacrimal gland tumors.
Andreoli MT, Aakalu V, Setabutr P
Otolaryngol Head Neck Surg 2015 Feb;152(2):279-83. Epub 2014 Nov 10 doi: 10.1177/0194599814556624. PMID: 25385802Free PMC Article
Postoperative intensity-modulated radiation therapy for cancers of the paranasal sinuses, nasal cavity, and lacrimal glands: technique, early outcomes, and toxicity.
Hoppe BS, Wolden SL, Zelefsky MJ, Mechalakos JG, Shah JP, Kraus DH, Lee N
Head Neck 2008 Jul;30(7):925-32. doi: 10.1002/hed.20800. PMID: 18302261

Diagnosis

Primary poorly differentiated lacrimal gland adenocarcinoma in left ocular region: A rare case report.
Xia F, Ling W, Zhang J, Zhang Y, Ma X
Medicine (Baltimore) 2018 Sep;97(37):e12198. doi: 10.1097/MD.0000000000012198. PMID: 30212949Free PMC Article
Epidemiological trends in malignant lacrimal gland tumors.
Andreoli MT, Aakalu V, Setabutr P
Otolaryngol Head Neck Surg 2015 Feb;152(2):279-83. Epub 2014 Nov 10 doi: 10.1177/0194599814556624. PMID: 25385802Free PMC Article
Postoperative radiotherapy with volumetric modulated arc therapy of lacrimal gland carcinoma: two case reports and literature review.
Orlandi E, Takanen S, Giandini T, Iannacone E, Fontanella W, Locati L, Carrara M, Bossi P, Bergamini C, Granata R, Tombolini V, Ibba T, Licitra L, Pignoli E, Fallai C
Future Oncol 2014 Nov;10(14):2111-20. doi: 10.2217/fon.14.148. PMID: 25471025

Therapy

Outcomes in patients with lacrimal gland carcinoma treated with definitive radiotherapy or eye-sparing surgery followed by adjuvant radiotherapy.
Lin YH, Huang SM, Yap WK, Yang JW, Yeung L, Tsan DL, Chang JT, Chen LC
Radiat Oncol 2020 Jun 22;15(1):156. doi: 10.1186/s13014-020-01601-8. PMID: 32571366Free PMC Article
Primary poorly differentiated lacrimal gland adenocarcinoma in left ocular region: A rare case report.
Xia F, Ling W, Zhang J, Zhang Y, Ma X
Medicine (Baltimore) 2018 Sep;97(37):e12198. doi: 10.1097/MD.0000000000012198. PMID: 30212949Free PMC Article
Postoperative intensity-modulated radiation therapy for cancers of the paranasal sinuses, nasal cavity, and lacrimal glands: technique, early outcomes, and toxicity.
Hoppe BS, Wolden SL, Zelefsky MJ, Mechalakos JG, Shah JP, Kraus DH, Lee N
Head Neck 2008 Jul;30(7):925-32. doi: 10.1002/hed.20800. PMID: 18302261

Prognosis

Epidemiological trends in malignant lacrimal gland tumors.
Andreoli MT, Aakalu V, Setabutr P
Otolaryngol Head Neck Surg 2015 Feb;152(2):279-83. Epub 2014 Nov 10 doi: 10.1177/0194599814556624. PMID: 25385802Free PMC Article
Postoperative intensity-modulated radiation therapy for cancers of the paranasal sinuses, nasal cavity, and lacrimal glands: technique, early outcomes, and toxicity.
Hoppe BS, Wolden SL, Zelefsky MJ, Mechalakos JG, Shah JP, Kraus DH, Lee N
Head Neck 2008 Jul;30(7):925-32. doi: 10.1002/hed.20800. PMID: 18302261

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