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Benign Pineal Region Neoplasm

MedGen UID:
56331
Concept ID:
C0154043
Neoplastic Process
Synonyms: Benign neoplasm of pineal gland; Benign Neoplasm of Pineal Parenchyma; Benign Neoplasm of the Pineal Parenchyma; Benign Pineal Area Neoplasm; Benign Pineal Area Tumor; Benign Pineal Parenchymal Neoplasm; Benign Pineal Parenchymal Tumor; Benign Pineal Region Tumor; Benign tumor of pineal gland; Benign Tumor of Pineal Parenchyma; Benign Tumor of the Pineal Parenchyma; Pineal Parenchymal Neoplasms, Benign
SNOMED CT: Benign tumor of pineal gland (92294001); Benign neoplasm of pineal gland (92294001)

Definition

A neoplasm that arises from the pineal region and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Szathmari A, Beuriat PA, Vasiljevic A, Leblond P, Faure-Conter C, Claude L, Di Rocco F, Mottolese C
Childs Nerv Syst 2023 Sep;39(9):2317-2327. Epub 2022 Oct 15 doi: 10.1007/s00381-022-05649-7. PMID: 36242638
Májovský M, Netuka D, Beneš V
Acta Neurochir (Wien) 2016 Apr;158(4):663-669. Epub 2016 Feb 20 doi: 10.1007/s00701-016-2726-3. PMID: 26897024
Dempsey PK, Kondziolka D, Lunsford LD
Acta Neurochir (Wien) 1992;116(1):14-22. doi: 10.1007/BF01541248. PMID: 1615765

Recent clinical studies

Etiology

Zaccagna F, Brown FS, Allinson KSJ, Devadass A, Kapadia A, Massoud TF, Matys T
Clin Radiol 2022 Feb;77(2):e107-e119. Epub 2021 Nov 11 doi: 10.1016/j.crad.2021.09.020. PMID: 34774298
Starke RM, Cappuzzo JM, Erickson NJ, Sherman JH
J Neurosurg 2017 Aug;127(2):249-254. Epub 2016 Oct 21 doi: 10.3171/2016.8.JNS16220. PMID: 27767399
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Bruce JN, Stein BM
Neurosurg Clin N Am 1990 Jan;1(1):123-38. PMID: 2135964
Talerman A
Ann Pathol 1985;5(3):145-57. PMID: 3000396

Diagnosis

Upadhyayula PS, Neira JA, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:153-173. doi: 10.1007/978-3-031-23705-8_6. PMID: 37452938
Zaccagna F, Brown FS, Allinson KSJ, Devadass A, Kapadia A, Massoud TF, Matys T
Clin Radiol 2022 Feb;77(2):e107-e119. Epub 2021 Nov 11 doi: 10.1016/j.crad.2021.09.020. PMID: 34774298
Deiana G, Mottolese C, Hermier M, Louis-Tisserand G, Berthezene Y
Neurochirurgie 2015 Apr-Jun;61(2-3):113-22. Epub 2015 Feb 9 doi: 10.1016/j.neuchi.2014.10.111. PMID: 25676911
Baumgartner JE, Edwards MS
Neurosurg Clin N Am 1992 Oct;3(4):853-62. PMID: 1392580
Bruce JN, Stein BM
Neurosurg Clin N Am 1990 Jan;1(1):123-38. PMID: 2135964

Therapy

Szathmari A, Vasiljevic A, Di Rocco F, Beuriat PA, Mottolese C
Childs Nerv Syst 2023 Dec;39(12):3467-3474. Epub 2023 Oct 29 doi: 10.1007/s00381-023-06181-y. PMID: 37898987
Sonabend AM, Bowden S, Bruce JN
J Neurooncol 2016 Nov;130(2):351-366. Epub 2016 May 19 doi: 10.1007/s11060-016-2138-5. PMID: 27193692
Kelsey CR, Marks LB
J Neurooncol 2006 Jun;78(2):153-6. Epub 2006 Mar 31 doi: 10.1007/s11060-005-9073-1. PMID: 16575537
El-Bahy K, Kotb A, Galal A, El-Hakim A
Acta Neurochir (Wien) 2006 Apr;148(4):457-62. Epub 2006 Jan 27 doi: 10.1007/s00701-005-0722-0. PMID: 16437187
Herrmann HD, Winkler D, Westphal M
Acta Neurochir (Wien) 1992;116(2-4):137-46. doi: 10.1007/BF01540866. PMID: 1502947

Prognosis

Starke RM, Cappuzzo JM, Erickson NJ, Sherman JH
J Neurosurg 2017 Aug;127(2):249-254. Epub 2016 Oct 21 doi: 10.3171/2016.8.JNS16220. PMID: 27767399
Sonabend AM, Bowden S, Bruce JN
J Neurooncol 2016 Nov;130(2):351-366. Epub 2016 May 19 doi: 10.1007/s11060-016-2138-5. PMID: 27193692
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Baumgartner JE, Edwards MS
Neurosurg Clin N Am 1992 Oct;3(4):853-62. PMID: 1392580
Bruce JN, Stein BM
Neurosurg Clin N Am 1990 Jan;1(1):123-38. PMID: 2135964

Clinical prediction guides

Szathmari A, Vasiljevic A, Di Rocco F, Beuriat PA, Mottolese C
Childs Nerv Syst 2023 Dec;39(12):3467-3474. Epub 2023 Oct 29 doi: 10.1007/s00381-023-06181-y. PMID: 37898987
Jimenez-Heffernan JA, Alvarez F, Muñoz-Hernández P, Bárcena C, Azorin D, Bernal I, Pérez-Campos A
Acta Cytol 2021;65(2):111-122. Epub 2021 Jan 21 doi: 10.1159/000512723. PMID: 33477138
Tanrıkulu B, Özek MM
Childs Nerv Syst 2020 Jan;36(1):153-163. Epub 2019 May 29 doi: 10.1007/s00381-019-04204-1. PMID: 31144023
Starke RM, Cappuzzo JM, Erickson NJ, Sherman JH
J Neurosurg 2017 Aug;127(2):249-254. Epub 2016 Oct 21 doi: 10.3171/2016.8.JNS16220. PMID: 27767399
Talerman A
Ann Pathol 1985;5(3):145-57. PMID: 3000396

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