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Vitreous body disorder

MedGen UID:
56361
•Concept ID:
C0155365
•
Disease or Syndrome
Synonyms: disease of vitreous body; disease or disorder of vitreous body; Disorder of vitreous; Disorder of vitreous body; disorder of vitreous body; Disorder of vitreous cavity; vitreous body disease; vitreous body disease or disorder; Vitreous Body Disorder; vitreous body disorder; Vitreous disorder
SNOMED CT: Disorder of vitreous body (76682005); Disorder of vitreous cavity (418842009); Disorder of vitreous (418842009); Vitreous disorder (418842009)
 
Monarch Initiative: MONDO:0044137

Definition

Any disease affecting the vitreous body of the eye. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVitreous body disorder

Professional guidelines

PubMed

Evidence-based expert consensus on the management of primary central nervous system lymphoma in China.
Chen T, Liu Y, Wang Y, Chang Q, Wu J, Wang Z, Geng D, Yu JT, Li Y, Li XQ, Chen H, Zhuang D, Li J, Wang B, Jiang T, Lyu L, Song Y, Qiu X, Li W, Lin S, Zhang X, Lu D, Lei J, Chen Y, Mao Y
J Hematol Oncol 2022 Sep 29;15(1):136. doi: 10.1186/s13045-022-01356-7. PMID: 36176002Free PMC Article
Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Revisiting systemic treatment of bacterial endophthalmitis: a review of intravitreal penetration of systemic antibiotics.
Brockhaus L, Goldblum D, Eggenschwiler L, Zimmerli S, Marzolini C
Clin Microbiol Infect 2019 Nov;25(11):1364-1369. Epub 2019 Feb 14 doi: 10.1016/j.cmi.2019.01.017. PMID: 30771529

Recent clinical studies

Etiology

Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Pediatric vitreous hemorrhage: A narrative review.
Naik AU, Rishi E, Rishi P
Indian J Ophthalmol 2019 Jun;67(6):732-739. doi: 10.4103/ijo.IJO_688_18. PMID: 31124481Free PMC Article
The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole.
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995
Vitreous proteomics and diabetic retinopathy.
Walia S, Clermont AC, Gao BB, Aiello LP, Feener EP
Semin Ophthalmol 2010 Sep-Nov;25(5-6):289-94. doi: 10.3109/08820538.2010.518912. PMID: 21091014Free PMC Article
Malignant glaucoma.
Luntz MH, Rosenblatt M
Surv Ophthalmol 1987 Sep-Oct;32(2):73-93. doi: 10.1016/0039-6257(87)90101-9. PMID: 3317956

Diagnosis

Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Vitreous and Vision Degrading Myodesopsia.
Sebag J
Prog Retin Eye Res 2020 Nov;79:100847. Epub 2020 Mar 6 doi: 10.1016/j.preteyeres.2020.100847. PMID: 32151758
The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole.
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995
Vitreous floaters.
Roufail ED, Polkinghorne P
Compr Ophthalmol Update 2006 Jul-Aug;7(4):171-7. PMID: 17007730
Imaging vitreous.
Sebag J
Eye (Lond) 2002 Jul;16(4):429-39. doi: 10.1038/sj.eye.6700201. PMID: 12101450

Therapy

Diagnosis and management of vitreoretinal lymphoma: present and future treatment perspectives.
Kaburaki T, Taoka K
Jpn J Ophthalmol 2023 Jul;67(4):363-381. Epub 2023 May 20 doi: 10.1007/s10384-023-00997-6. PMID: 37209195
Evidence-based expert consensus on the management of primary central nervous system lymphoma in China.
Chen T, Liu Y, Wang Y, Chang Q, Wu J, Wang Z, Geng D, Yu JT, Li Y, Li XQ, Chen H, Zhuang D, Li J, Wang B, Jiang T, Lyu L, Song Y, Qiu X, Li W, Lin S, Zhang X, Lu D, Lei J, Chen Y, Mao Y
J Hematol Oncol 2022 Sep 29;15(1):136. doi: 10.1186/s13045-022-01356-7. PMID: 36176002Free PMC Article
Revisiting systemic treatment of bacterial endophthalmitis: a review of intravitreal penetration of systemic antibiotics.
Brockhaus L, Goldblum D, Eggenschwiler L, Zimmerli S, Marzolini C
Clin Microbiol Infect 2019 Nov;25(11):1364-1369. Epub 2019 Feb 14 doi: 10.1016/j.cmi.2019.01.017. PMID: 30771529
Enzymatic Vitrectomy and Pharmacologic Vitreodynamics.
Shah AR, Trese MT
Dev Ophthalmol 2016;55:357-64. Epub 2015 Oct 26 doi: 10.1159/000438962. PMID: 26501959
Age-related macular degeneration.
Cheung LK, Eaton A
Pharmacotherapy 2013 Aug;33(8):838-55. Epub 2013 Apr 11 doi: 10.1002/phar.1264. PMID: 23580402

Prognosis

Diagnosis and management of vitreoretinal lymphoma: present and future treatment perspectives.
Kaburaki T, Taoka K
Jpn J Ophthalmol 2023 Jul;67(4):363-381. Epub 2023 May 20 doi: 10.1007/s10384-023-00997-6. PMID: 37209195
Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Protein Biomarkers in Uveitis.
Bansal R, Gupta A
Front Immunol 2020;11:610428. Epub 2020 Dec 3 doi: 10.3389/fimmu.2020.610428. PMID: 33343583Free PMC Article
The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole.
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995
Vitreous floaters.
Roufail ED, Polkinghorne P
Compr Ophthalmol Update 2006 Jul-Aug;7(4):171-7. PMID: 17007730

Clinical prediction guides

Mendelian randomization study confirms causal relationship between myopia and vitreous disorders.
Xu J, Mo Y
BMC Med Genomics 2023 Oct 9;16(1):238. doi: 10.1186/s12920-023-01673-x. PMID: 37814298Free PMC Article
Protein Biomarkers in Uveitis.
Bansal R, Gupta A
Front Immunol 2020;11:610428. Epub 2020 Dec 3 doi: 10.3389/fimmu.2020.610428. PMID: 33343583Free PMC Article
Pediatric vitreous hemorrhage: A narrative review.
Naik AU, Rishi E, Rishi P
Indian J Ophthalmol 2019 Jun;67(6):732-739. doi: 10.4103/ijo.IJO_688_18. PMID: 31124481Free PMC Article
The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole.
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995
Vitreous floaters.
Roufail ED, Polkinghorne P
Compr Ophthalmol Update 2006 Jul-Aug;7(4):171-7. PMID: 17007730

Recent systematic reviews

Prognostic factors for the development and progression of proliferative diabetic retinopathy in people with diabetic retinopathy.
Perais J, Agarwal R, Evans JR, Loveman E, Colquitt JL, Owens D, Hogg RE, Lawrenson JG, Takwoingi Y, Lois N
Cochrane Database Syst Rev 2023 Feb 22;2(2):CD013775. doi: 10.1002/14651858.CD013775.pub2. PMID: 36815723Free PMC Article
Systematic review of epidemiological studies evaluating the association between exposure to man-made vitreous fibers and non-malignant respiratory diseases.
Suder Egnot N, Allen H, Hazan R, Vater MF, Denic-Roberts H, LeClaire R, Marsh GM
Regul Toxicol Pharmacol 2023 Mar;139:105361. Epub 2023 Feb 18 doi: 10.1016/j.yrtph.2023.105361. PMID: 36806369
Ocriplasmin for treatment of vitreomacular traction and macular hole: A systematic literature review and individual participant data meta-analysis of randomized, controlled, double-masked trials.
Jackson TL, Haller J, Blot KH, Duchateau L, Lescrauwaet B
Surv Ophthalmol 2022 May-Jun;67(3):697-711. Epub 2021 Sep 2 doi: 10.1016/j.survophthal.2021.08.003. PMID: 34480895
Changes in aqueous and vitreous inflammatory cytokine levels in diabetic macular oedema: a systematic review and meta-analysis.
Minaker SA, Mason RH, Lahaie Luna G, Farahvash A, Garg A, Bhambra N, Bapat P, Muni RH
Acta Ophthalmol 2022 Feb;100(1):e53-e70. Epub 2021 May 4 doi: 10.1111/aos.14891. PMID: 33945678
Ocular pharmacology of topotecan and its activity in retinoblastoma.
Schaiquevich P, Carcaboso AM, Buitrago E, Taich P, Opezzo J, Bramuglia G, Chantada GL
Retina 2014 Sep;34(9):1719-27. doi: 10.1097/IAE.0000000000000253. PMID: 25099219

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