U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Middle ear cholesterol granuloma

MedGen UID:
56364
•Concept ID:
C0155492
•
Pathologic Function
Synonyms: cholesterin granuloma; Cholesterin granuloma of middle ear; Cholesterin Granuloma of Middle Ear; cholesterin granuloma of middle ear; Cholesterol granuloma of middle ear; Cholesterol Granuloma of Middle Ear; Cholesterol Granuloma of the Middle Ear; Middle Ear Cholesterol Granuloma; middle ear cholesterol granuloma
SNOMED CT: Cholesterin granuloma of middle ear (28371001); Cholesterol granuloma of middle ear (28371001)
 
Monarch Initiative: MONDO:0001141

Definition

As accumulation of granulation tissue in the middle ear that results from the degeneration of blood and a chronic inflammatory response. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMiddle ear cholesterol granuloma

Professional guidelines

PubMed

Intractable otitis media - Pathogenesis and treatment of Eosinophilic otitis media (EOM) and otitis media with Antineutrophil cytoplasmic antibody (ANCA) -associated vasculitis (OMAAV).
Yoshida N
Auris Nasus Larynx 2023 Apr;50(2):171-179. Epub 2022 Aug 5 doi: 10.1016/j.anl.2022.07.005. PMID: 35934599
Lesions involving the jugular foramen: clinical characteristics and surgical management.
Li W, Dai C
Acta Otolaryngol 2015 Jun;135(6):565-71. Epub 2015 Feb 26 doi: 10.3109/00016489.2014.1003094. PMID: 25719346
Lesions of the petrous apex: diagnosis and management.
Isaacson B, Kutz JW, Roland PS
Otolaryngol Clin North Am 2007 Jun;40(3):479-519, viii. doi: 10.1016/j.otc.2007.03.003. PMID: 17544693

Recent clinical studies

Etiology

Invasive middle ear cholesterol granuloma involving the basal turn of the cochlea with profound sensorineural hearing loss.
Murugasu E, Yong TT, Yoon CP
Otol Neurotol 2004 May;25(3):231-5. doi: 10.1097/00129492-200405000-00005. PMID: 15129097
Surgical intervention in middle-ear cholesterol granuloma.
Maeta M, Saito R, Nakagawa F, Miyahara T
J Laryngol Otol 2003 May;117(5):344-8. doi: 10.1258/002221503321626366. PMID: 12803782
A retrospective study on cholesteatoma otitis media coexisting with cholesterol granuloma.
Luo L, Gong S, Bai G, Wang J
J Huazhong Univ Sci Technolog Med Sci 2002;22(2):168-70. doi: 10.1007/BF02857685. PMID: 12658765

Diagnosis

Bilateral middle ear cholesterol granuloma in familial hypercholesterolemia.
Masaany M, Siti HS, Nurliza I, Mazita A
Otolaryngol Head Neck Surg 2008 Jun;138(6):803-4. doi: 10.1016/j.otohns.2008.02.020. PMID: 18503863
A large and uncharacteristically aggressive cholesterol granuloma of the middle ear.
Martin TP, Tzifa KT, Chavda S, Irving RM
J Laryngol Otol 2005 Dec;119(12):1001-3. doi: 10.1258/002221505775010661. PMID: 16354369
Invasive middle ear cholesterol granuloma involving the basal turn of the cochlea with profound sensorineural hearing loss.
Murugasu E, Yong TT, Yoon CP
Otol Neurotol 2004 May;25(3):231-5. doi: 10.1097/00129492-200405000-00005. PMID: 15129097
A retrospective study on cholesteatoma otitis media coexisting with cholesterol granuloma.
Luo L, Gong S, Bai G, Wang J
J Huazhong Univ Sci Technolog Med Sci 2002;22(2):168-70. doi: 10.1007/BF02857685. PMID: 12658765
Middle ear cholesterol granuloma.
Kerstetter JR, Dolan KD
Ann Otol Rhinol Laryngol 1991 Oct;100(10):866-8. doi: 10.1177/000348949110001015. PMID: 1952656

Prognosis

Analysis of surgical treatment for middle-ear cholesterol granuloma.
Matsuda Y, Kurita T, Ueda Y, Ito S, Nakashima T
J Laryngol Otol Suppl 2009;(31):90-6. doi: 10.1017/S0022215109005167. PMID: 19460212
Surgical intervention in middle-ear cholesterol granuloma.
Maeta M, Saito R, Nakagawa F, Miyahara T
J Laryngol Otol 2003 May;117(5):344-8. doi: 10.1258/002221503321626366. PMID: 12803782

Clinical prediction guides

A retrospective study on cholesteatoma otitis media coexisting with cholesterol granuloma.
Luo L, Gong S, Bai G, Wang J
J Huazhong Univ Sci Technolog Med Sci 2002;22(2):168-70. doi: 10.1007/BF02857685. PMID: 12658765

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...