Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Vascular malformation

MedGen UID:: 56387
•Concept ID:: C0158570
•: Anatomical Abnormality

Synonyms:	Malformation, Vascular; Malformations, Vascular; Vascular Malformation; Vascular Malformations
SNOMED CT:	Vascular malformation (783806000); Vascular anomaly (783806000)

Monarch Initiative:	MONDO:0024291

Definition

A non-neoplastic disorder that is the result of defects of vascular morphogenesis. [from MONDO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVVascular malformation

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Disorder of cardiovascular system
        Abnormality of the cardiovascular system
        Vascular malformation
        Arterio-Arterial Fistula
        Anomalous origin of left coronary artery from the pulmonary artery
        Arteriovenous malformation
        Arteriovenous fistula
        Arteriovenous fistula of pulmonary vessels
        Arteriovenous fistulas of celiac and mesenteric vessels
        Carotid cavernous fistula
        Congenital arteriovenous fistula
        Peripheral arteriovenous fistula
        Arteriovenous Malformation, Intracranial
        Vein of Galen malformation
        Gastrointestinal arteriovenous malformation
        Colonic arteriovenous malformation
        Duodenal arteriovenous malformation
        Gastric arteriovenous malformation
        Jejunal arteriovenous malformation
        Rectal arteriovenous malformation
        Hepatic arteriovenous malformation
        Pelvic arteriovenous malformation
        Pulmonary arteriovenous malformation
        Spinal arteriovenous malformation
        Uterine arteriovenous malformation
        Celiac artery stenosis from compression by median arcuate ligament of diaphragm
        Hereditary hemorrhagic telangiectasia
        Hereditary hemorrhagic telangiectasia type 3
        Hereditary hemorrhagic telangiectasia type 4
        Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome
        Telangiectasia, hereditary hemorrhagic, type 1
        Telangiectasia, hereditary hemorrhagic, type 2
        Telangiectasia, hereditary hemorrhagic, type 5
        May-Thurner syndrome
        Persistent left superior vena cava
        Absent right superior vena cava
        Bilateral superior vena cava
        Bilateral superior vena cava with bridging vein
        Bilateral superior vena cava with no bridging vein
        Left superior vena cava draining directly to the left atrium
        Left superior vena cava draining to coronary sinus
        Pulmonary valve atresia
        Pulmonary atresia with intact ventricular septum
        Pulmonary atresia with ventricular septal defect
        Scimitar anomaly
        Single umbilical artery
        Vascular Fistula
        Vascular malformation of the nervous system
        Central Nervous System Cavernous Hemangioma
        Intracranial cavernous angioma
        Central Nervous System Venous Angioma
        Cerebral arteriovenous malformation
        Cerebral cavernous malformation
        Hereditary cavernous hemangioma of brain
        Meningioangiomatosis
        Sinus pericranii
        Vascular ring

Professional guidelines

PubMed

Infantile hemangioma. Part 2: Management.

Sebaratnam DF, Rodríguez Bandera AL, Wong LF, Wargon O
J Am Acad Dermatol 2021 Dec;85(6):1395-1404. Epub 2021 Aug 19 doi: 10.1016/j.jaad.2021.08.020. PMID: 34419523

Vascular Anomalies: Diagnosis of Complicated Anomalies and New Medical Treatment Options.

Adams DM, Ricci KW
Hematol Oncol Clin North Am 2019 Jun;33(3):455-470. doi: 10.1016/j.hoc.2019.01.011. PMID: 31030813

Treatment of Venous Malformations: The Data, Where We Are, and How It Is Done.

Hage AN, Chick JFB, Srinivasa RN, Bundy JJ, Chauhan NR, Acord M, Gemmete JJ
Tech Vasc Interv Radiol 2018 Jun;21(2):45-54. Epub 2018 Mar 8 doi: 10.1053/j.tvir.2018.03.001. PMID: 29784122

See all (207)

Recent clinical studies

Etiology

Infantile hemangioma. Part 2: Management.

Sebaratnam DF, Rodríguez Bandera AL, Wong LF, Wargon O
J Am Acad Dermatol 2021 Dec;85(6):1395-1404. Epub 2021 Aug 19 doi: 10.1016/j.jaad.2021.08.020. PMID: 34419523

PIK3CA vascular overgrowth syndromes: an update.

Hughes M, Hao M, Luu M
Curr Opin Pediatr 2020 Aug;32(4):539-546. doi: 10.1097/MOP.0000000000000923. PMID: 32692051

Vascular malformations syndromes: an update.

Martinez-Lopez A, Salvador-Rodriguez L, Montero-Vilchez T, Molina-Leyva A, Tercedor-Sanchez J, Arias-Santiago S
Curr Opin Pediatr 2019 Dec;31(6):747-753. doi: 10.1097/MOP.0000000000000812. PMID: 31693582

Vascular Anomalies: Diagnosis of Complicated Anomalies and New Medical Treatment Options.

Adams DM, Ricci KW
Hematol Oncol Clin North Am 2019 Jun;33(3):455-470. doi: 10.1016/j.hoc.2019.01.011. PMID: 31030813

Pediatric Congenital Cerebrovascular Anomalies.

Goyal P, Mangla R, Gupta S, Malhotra A, Almast J, Sapire J, Kolar B
J Neuroimaging 2019 Mar;29(2):165-181. Epub 2018 Oct 31 doi: 10.1111/jon.12575. PMID: 30378722

See all (982)

Diagnosis

Uterine Arteriovenous Malformation: A Pictorial Review of Diagnosis and Management.

Hoang VT, Van HAT, Trinh CT, Pham NTT, Huynh C, Ha TN, Huynh PH, Nguyen HQ, Vo UG, Nguyen TT
J Endovasc Ther 2021 Oct;28(5):659-675. Epub 2021 Jun 18 doi: 10.1177/15266028211025022. PMID: 34142901

Lymphatic malformations.

Kulungowski AM, Patel M
Semin Pediatr Surg 2020 Oct;29(5):150971. Epub 2020 Sep 16 doi: 10.1016/j.sempedsurg.2020.150971. PMID: 33069296

PIK3CA vascular overgrowth syndromes: an update.

Hughes M, Hao M, Luu M
Curr Opin Pediatr 2020 Aug;32(4):539-546. doi: 10.1097/MOP.0000000000000923. PMID: 32692051

Vascular Anomalies: Diagnosis of Complicated Anomalies and New Medical Treatment Options.

Adams DM, Ricci KW
Hematol Oncol Clin North Am 2019 Jun;33(3):455-470. doi: 10.1016/j.hoc.2019.01.011. PMID: 31030813

Vascular Anomalies.

Taghinia AH, Upton J
J Hand Surg Am 2018 Dec;43(12):1113-1121. Epub 2018 Jun 12 doi: 10.1016/j.jhsa.2018.03.046. PMID: 29907461

See all (1600)

Therapy

Infantile hemangioma. Part 2: Management.

Sebaratnam DF, Rodríguez Bandera AL, Wong LF, Wargon O
J Am Acad Dermatol 2021 Dec;85(6):1395-1404. Epub 2021 Aug 19 doi: 10.1016/j.jaad.2021.08.020. PMID: 34419523

Treatment Update of Port-Wine Stain: A Narrative Review.

Fölster-Holst R, Shukla R, Kassir M, Galadari H, Lotti T, Wollina U, Grabbe S, Goldust M
J Drugs Dermatol 2021 May 1;20(5):515-518. doi: 10.36849/JDD.5005. PMID: 33938700

Vascular malformations syndromes: an update.

Surgery for epilepsy.

West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346 Free PMC Article

Treatment of Venous Malformations: The Data, Where We Are, and How It Is Done.

Hage AN, Chick JFB, Srinivasa RN, Bundy JJ, Chauhan NR, Acord M, Gemmete JJ
Tech Vasc Interv Radiol 2018 Jun;21(2):45-54. Epub 2018 Mar 8 doi: 10.1053/j.tvir.2018.03.001. PMID: 29784122

See all (522)

Prognosis

Pediatric Congenital Cerebrovascular Anomalies.

Goyal P, Mangla R, Gupta S, Malhotra A, Almast J, Sapire J, Kolar B
J Neuroimaging 2019 Mar;29(2):165-181. Epub 2018 Oct 31 doi: 10.1111/jon.12575. PMID: 30378722

Vascular Lesions.

Jahnke MN
Pediatr Ann 2016 Aug 1;45(8):e299-305. doi: 10.3928/19382359-20160720-08. PMID: 27517358

CLOVES syndrome.

Bloom J, Upton J 3rd
J Hand Surg Am 2013 Dec;38(12):2508-12. Epub 2013 Oct 23 doi: 10.1016/j.jhsa.2013.08.120. PMID: 24161472

Sturge-Weber syndrome.

Nabbout R, Juhász C
Handb Clin Neurol 2013;111:315-21. doi: 10.1016/B978-0-444-52891-9.00037-3. PMID: 23622182

Intracranial hemorrhage.

Naidech AM
Am J Respir Crit Care Med 2011 Nov 1;184(9):998-1006. doi: 10.1164/rccm.201103-0475CI. PMID: 22167847 Free PMC Article

See all (562)

Clinical prediction guides

Sirolimus (Rapamycin) for Slow-Flow Malformations in Children: The Observational-Phase Randomized Clinical PERFORMUS Trial.

Maruani A, Tavernier E, Boccara O, Mazereeuw-Hautier J, Leducq S, Bessis D, Guibaud L, Vabres P, Carmignac V, Mallet S, Barbarot S, Chiaverini C, Droitcourt C, Bursztejn AC, Lengellé C, Woillard JB, Herbreteau D, Le Touze A, Joly A, Léauté-Labrèze C, Powell J, Bourgoin H, Gissot V, Giraudeau B, Morel B
JAMA Dermatol 2021 Nov 1;157(11):1289-1298. doi: 10.1001/jamadermatol.2021.3459. PMID: 34524406 Free PMC Article

Lymphatic malformations.

Kulungowski AM, Patel M
Semin Pediatr Surg 2020 Oct;29(5):150971. Epub 2020 Sep 16 doi: 10.1016/j.sempedsurg.2020.150971. PMID: 33069296

Hepatic hemangioma: What internists need to know.

Leon M, Chavez L, Surani S
World J Gastroenterol 2020 Jan 7;26(1):11-20. doi: 10.3748/wjg.v26.i1.11. PMID: 31933511 Free PMC Article

Surgery for epilepsy.

Vascular Lesions.

Jahnke MN
Pediatr Ann 2016 Aug 1;45(8):e299-305. doi: 10.3928/19382359-20160720-08. PMID: 27517358

See all (477)

Recent systematic reviews

Surgical Treatment of Peripheral Vascular Malformations: A Systematic Review and Meta-Analysis.

Lokhorst MM, Jolink F, Horbach SER, Spuls PI, van der Horst CMAM
Plast Reconstr Surg 2021 May 1;147(5):1149-1161. doi: 10.1097/PRS.0000000000007837. PMID: 33890897

Management of vascular malformations in the Oral and maxillofacial region: A systematic review.

Ramakrishnan K, Palanivel I, Narayanan V, Chandran S, Gurram P
J Stomatol Oral Maxillofac Surg 2021 Dec;122(6):588-599. Epub 2021 Jan 2 doi: 10.1016/j.jormas.2020.12.010. PMID: 33400992

Surgery for epilepsy.

Parkes Weber syndrome-Diagnostic and management paradigms: A systematic review.

Banzic I, Brankovic M, Maksimović Ž, Davidović L, Marković M, Rančić Z
Phlebology 2017 Jul;32(6):371-383. Epub 2016 Aug 9 doi: 10.1177/0268355516664212. PMID: 27511883

Surgery for epilepsy.

West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264

See all (33)

MedGen

National Center for Biotechnology Information

Send to:

Vascular malformation

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

Related information

Recent activity