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Photoallergic dermatitis

MedGen UID:
56514
•Concept ID:
C0162824
•
Disease or Syndrome
Synonyms: Contact Dermatitides, Photoallergic; Contact Dermatitides, Photosensitive; Contact Dermatitis, Photoallergic; Contact Dermatitis, Photosensitive; Dermatitides, Photoallergic; Dermatitides, Photoallergic Contact; Dermatitides, Photocontact; Dermatitides, Photosensitive Contact; Dermatitis, Contact, Photoallergic; Dermatitis, Contact, Photosensitive; Dermatitis, Photoallergic; Dermatitis, Photoallergic Contact; Dermatitis, Photocontact; Dermatitis, Photosensitive Contact; Photoallergic Contact Dermatitides; Photoallergic Contact Dermatitis; Photoallergic Dermatitides; Photoallergic Dermatitis; Photocontact Dermatitides; Photocontact Dermatitis; Photosensitive Contact Dermatitides; Photosensitive Contact Dermatitis
SNOMED CT: Allergic photocontact eczema (111209006); Photoallergic dermatitis (111209006); Photoallergic contact dermatitis (111209006); Photoallergic eczema (111209006)
 
Monarch Initiative: MONDO:0006596

Definition

A delayed hypersensitivity involving the reaction between sunlight or other radiant energy source and a chemical substance to which the individual has been previously exposed and sensitized. It manifests as a papulovesicular, eczematous, or exudative dermatitis occurring chiefly on the light-exposed areas of the skin. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPhotoallergic dermatitis

Professional guidelines

PubMed

Allergic contact dermatitis: Patient management and education.
Mowad CM, Anderson B, Scheinman P, Pootongkam S, Nedorost S, Brod B
J Am Acad Dermatol 2016 Jun;74(6):1043-54. doi: 10.1016/j.jaad.2015.02.1144. PMID: 27185422
Photodermatoses: classification, evaluation and management.
Bylaite M, Grigaitiene J, Lapinskaite GS
Br J Dermatol 2009 Nov;161 Suppl 3:61-8. doi: 10.1111/j.1365-2133.2009.09451.x. PMID: 19775359
Management of polymorphous light eruption : clinical course, pathogenesis, diagnosis and intervention.
Fesq H, Ring J, Abeck D
Am J Clin Dermatol 2003;4(6):399-406. doi: 10.2165/00128071-200304060-00004. PMID: 12762832

Recent clinical studies

Etiology

Ketoprofen-induced Photoallergic Reaction.
Rosan T, Ljubojević Hadžavdić S
Acta Dermatovenerol Croat 2022 Nov;30(3):197-198. PMID: 36812283
Drug-induced photosensitivity: culprit drugs, potential mechanisms and clinical consequences.
Hofmann GA, Weber B
J Dtsch Dermatol Ges 2021 Jan;19(1):19-29. doi: 10.1111/ddg.14314. PMID: 33491908Free PMC Article
Allergic and photoallergic contact dermatitis to chlorpromazine.
Martínez-Doménech A, García-Legaz Martínez M, Ferrer-Guillén B, Magdaleno-Tapial J, Valenzuela-Oñate C, Esteve-Martínez A, Zaragoza-Ninet V, Pérez-Ferriols A
Australas J Dermatol 2020 Aug;61(3):e351-e353. Epub 2020 Mar 5 doi: 10.1111/ajd.13254. PMID: 32141075
Benzophenones.
Heurung AR, Raju SI, Warshaw EM
Dermatitis 2014 Jan-Feb;25(1):3-10. doi: 10.1097/DER.0000000000000025. PMID: 24407064
Photocontact dermatitis.
Deleo VA
Dermatol Ther 2004;17(4):279-88. doi: 10.1111/j.1396-0296.2004.04026.x. PMID: 15327473

Diagnosis

Photosensitizing drug reactions.
Montgomery S, Worswick S
Clin Dermatol 2022 Jan-Feb;40(1):57-63. Epub 2021 Aug 8 doi: 10.1016/j.clindermatol.2021.08.014. PMID: 35190066
Ketoprofen-induced photoallergic dermatitis.
Loh TY, Cohen PR
Indian J Med Res 2016 Dec;144(6):803-806. doi: 10.4103/ijmr.IJMR_626_16. PMID: 28474616Free PMC Article
Cutaneous adverse effects of targeted therapies: Part I: Inhibitors of the cellular membrane.
Macdonald JB, Macdonald B, Golitz LE, LoRusso P, Sekulic A
J Am Acad Dermatol 2015 Feb;72(2):203-18; quiz 219-20. doi: 10.1016/j.jaad.2014.07.032. PMID: 25592338
Photoallergy.
Honari G
Rev Environ Health 2014;29(3):233-42. doi: 10.1515/reveh-2014-0067. PMID: 25274941
Photocontact dermatitis.
Deleo VA
Dermatol Ther 2004;17(4):279-88. doi: 10.1111/j.1396-0296.2004.04026.x. PMID: 15327473

Therapy

Photosensitizing drug reactions.
Montgomery S, Worswick S
Clin Dermatol 2022 Jan-Feb;40(1):57-63. Epub 2021 Aug 8 doi: 10.1016/j.clindermatol.2021.08.014. PMID: 35190066
Ketoprofen-induced photoallergic dermatitis.
Loh TY, Cohen PR
Indian J Med Res 2016 Dec;144(6):803-806. doi: 10.4103/ijmr.IJMR_626_16. PMID: 28474616Free PMC Article
Cutaneous adverse effects of targeted therapies: Part I: Inhibitors of the cellular membrane.
Macdonald JB, Macdonald B, Golitz LE, LoRusso P, Sekulic A
J Am Acad Dermatol 2015 Feb;72(2):203-18; quiz 219-20. doi: 10.1016/j.jaad.2014.07.032. PMID: 25592338
Benzophenones.
Heurung AR, Raju SI, Warshaw EM
Dermatitis 2014 Jan-Feb;25(1):3-10. doi: 10.1097/DER.0000000000000025. PMID: 24407064
Photocontact dermatitis.
Deleo VA
Dermatol Ther 2004;17(4):279-88. doi: 10.1111/j.1396-0296.2004.04026.x. PMID: 15327473

Prognosis

Photodermatoses in skin of colour.
Gutierrez D, Gaulding JV, Motta Beltran AF, Lim HW, Pritchett EN
J Eur Acad Dermatol Venereol 2018 Nov;32(11):1879-1886. Epub 2018 Jul 15 doi: 10.1111/jdv.15115. PMID: 29888465
Ketoprofen-induced photoallergic dermatitis.
Loh TY, Cohen PR
Indian J Med Res 2016 Dec;144(6):803-806. doi: 10.4103/ijmr.IJMR_626_16. PMID: 28474616Free PMC Article
Update on photodermatoses.
Santoro FA, Lim HW
Semin Cutan Med Surg 2011 Dec;30(4):229-38. doi: 10.1016/j.sder.2011.07.007. PMID: 22123421
Photocontact dermatitis.
Deleo VA
Dermatol Ther 2004;17(4):279-88. doi: 10.1111/j.1396-0296.2004.04026.x. PMID: 15327473
Sesquiterpene lactone allergy.
Warshaw EM, Zug KA
Am J Contact Dermat 1996 Mar;7(1):1-23. doi: 10.1016/s1046-199x(96)90028-7. PMID: 8796737

Clinical prediction guides

Anticancer treatments and photosensitivity.
Sibaud V
J Eur Acad Dermatol Venereol 2022 Jun;36 Suppl 6(Suppl 6):51-58. doi: 10.1111/jdv.18200. PMID: 35738806Free PMC Article
Chemical photoallergy: photobiochemical mechanisms, classification, and risk assessments.
Onoue S, Seto Y, Sato H, Nishida H, Hirota M, Ashikaga T, Api AM, Basketter D, Tokura Y
J Dermatol Sci 2017 Jan;85(1):4-11. Epub 2016 Aug 6 doi: 10.1016/j.jdermsci.2016.08.005. PMID: 27528585
Cutaneous adverse effects of targeted therapies: Part I: Inhibitors of the cellular membrane.
Macdonald JB, Macdonald B, Golitz LE, LoRusso P, Sekulic A
J Am Acad Dermatol 2015 Feb;72(2):203-18; quiz 219-20. doi: 10.1016/j.jaad.2014.07.032. PMID: 25592338
Esomeprazole-induced photoallergic dermatitis.
Shukla A, Mahapatra A, Gogtay N, Khopkar U
J Postgrad Med 2010 Jul-Sep;56(3):229-31. doi: 10.4103/0022-3859.68648. PMID: 20739778
Photoallergic contact dermatitis.
Goossens A
Photodermatol Photoimmunol Photomed 2004 Jun;20(3):121-5. doi: 10.1111/j.1600-0781.2004.00092.x. PMID: 15144388

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