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Gas retention

MedGen UID:
568893
•Concept ID:
C0333139
•
Finding
Synonyms: Pneumatosis; Unusual gas collection
SNOMED CT: Gas retention (87241003); Pneumatosis (87241003); Unusual gas collection (87241003)

Definition

The presence of gas in an anatomical location where it is not normally found. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGas retention

Professional guidelines

PubMed

Phosgene inhalation toxicity: Update on mechanisms and mechanism-based treatment strategies.
Pauluhn J
Toxicology 2021 Feb 28;450:152682. Epub 2021 Jan 20 doi: 10.1016/j.tox.2021.152682. PMID: 33484734
Fluid administration and monitoring in ARDS: which management?
Vignon P, Evrard B, Asfar P, Busana M, Calfee CS, Coppola S, Demiselle J, Geri G, Jozwiak M, Martin GS, Gattinoni L, Chiumello D
Intensive Care Med 2020 Dec;46(12):2252-2264. Epub 2020 Nov 9 doi: 10.1007/s00134-020-06310-0. PMID: 33169217Free PMC Article
Perfluorocarbons for the treatment of decompression illness: how to bridge the gap between theory and practice.
Mayer D, Ferenz KB
Eur J Appl Physiol 2019 Dec;119(11-12):2421-2433. Epub 2019 Nov 4 doi: 10.1007/s00421-019-04252-0. PMID: 31686213Free PMC Article

Recent clinical studies

Etiology

Effect of Chicory-derived Inulin on Abdominal Sensations and Bowel Motor Function.
Azpiroz F, Molne L, Mendez S, Nieto A, Manichanh C, Mego M, Accarino A, Santos J, Sailer M, Theis S, Guarner F
J Clin Gastroenterol 2017 Aug;51(7):619-625. doi: 10.1097/MCG.0000000000000723. PMID: 27680592Free PMC Article
Colonic gas transit in patients with bloating: the effect of an electromechanical stimulator of the abdominal wall.
Tremolaterra F, Pascariello A, Gallotta S, Ciacci C, Iovino P
Tech Coloproctol 2013 Aug;17(4):405-10. Epub 2012 Dec 4 doi: 10.1007/s10151-012-0951-1. PMID: 23207715
Impaired intestinal gas clearance during marked hyperglycemia in patients with functional abdominal bloating.
Hernando-Harder AC, Riddinger F, Krammer HJ, Brade J, Singer MV, Harder H
Digestion 2006;74(3-4):155-61. Epub 2007 Mar 6 doi: 10.1159/000100499. PMID: 17341848
Origin of gas retention and symptoms in patients with bloating.
Salvioli B, Serra J, Azpiroz F, Lorenzo C, Aguade S, Castell J, Malagelada JR
Gastroenterology 2005 Mar;128(3):574-9. doi: 10.1053/j.gastro.2004.12.047. PMID: 15765392
Lipid-induced intestinal gas retention in irritable bowel syndrome.
Serra J, Salvioli B, Azpiroz F, Malagelada JR
Gastroenterology 2002 Sep;123(3):700-6. doi: 10.1053/gast.2002.35394. PMID: 12198695

Diagnosis

Intracellular vesicle entrapment of nanobubble ultrasound contrast agents targeted to PSMA promotes prolonged enhancement and stability in vivo and in vitro.
Perera RH, Abenojar E, Nittayacharn P, Wang X, Ramamurthy G, Peiris P, Bederman I, Basilion JP, Exner AA
Nanotheranostics 2022;6(3):270-285. Epub 2022 Feb 14 doi: 10.7150/ntno.64735. PMID: 35223380Free PMC Article
Effect of prucalopride on intestinal gas tolerance in patients with functional bowel disorders and constipation.
Malagelada C, Nieto A, Mendez S, Accarino A, Santos J, Malagelada JR, Azpiroz F
J Gastroenterol Hepatol 2017 Aug;32(8):1457-1462. doi: 10.1111/jgh.13733. PMID: 28090679
Impaired intestinal gas propulsion in manometrically proven dysmotility and in irritable bowel syndrome.
Serra J, Villoria A, Azpiroz F, Lobo B, Santos J, Accarino A, Malagelada JR
Neurogastroenterol Motil 2010 Apr;22(4):401-6, e91-2. Epub 2009 Dec 28 doi: 10.1111/j.1365-2982.2009.01447.x. PMID: 20047636
Intestinal gas retention in patients with idiopathic slow-transit constipation.
Hernando-Harder AC, Franke A, Wedel T, Böttner M, Krammer HJ, Singer MV, Harder H
Dig Dis Sci 2007 Oct;52(10):2667-75. Epub 2007 Mar 24 doi: 10.1007/s10620-006-9671-6. PMID: 17385036
Lipid-induced intestinal gas retention in irritable bowel syndrome.
Serra J, Salvioli B, Azpiroz F, Malagelada JR
Gastroenterology 2002 Sep;123(3):700-6. doi: 10.1053/gast.2002.35394. PMID: 12198695

Therapy

Effect of Chicory-derived Inulin on Abdominal Sensations and Bowel Motor Function.
Azpiroz F, Molne L, Mendez S, Nieto A, Manichanh C, Mego M, Accarino A, Santos J, Sailer M, Theis S, Guarner F
J Clin Gastroenterol 2017 Aug;51(7):619-625. doi: 10.1097/MCG.0000000000000723. PMID: 27680592Free PMC Article
Intestinal gas retention in patients with idiopathic slow-transit constipation.
Hernando-Harder AC, Franke A, Wedel T, Böttner M, Krammer HJ, Singer MV, Harder H
Dig Dis Sci 2007 Oct;52(10):2667-75. Epub 2007 Mar 24 doi: 10.1007/s10620-006-9671-6. PMID: 17385036
Reflex control of intestinal gas dynamics and tolerance in humans.
Harder H, Serra J, Azpiroz F, Malagelada JR
Am J Physiol Gastrointest Liver Physiol 2004 Jan;286(1):G89-94. Epub 2003 Aug 28 doi: 10.1152/ajpgi.00174.2003. PMID: 12946941
Gastric distension and duodenal lipid infusion modulate intestinal gas transit and tolerance in humans.
Serra J, Azpiroz F, Malagelada JR
Am J Gastroenterol 2002 Sep;97(9):2225-30. doi: 10.1111/j.1572-0241.2002.05976.x. PMID: 12358237
Mechanisms of intestinal gas retention in humans: impaired propulsion versus obstructed evacuation.
Serra J, Azpiroz F, Malagelada JR
Am J Physiol Gastrointest Liver Physiol 2001 Jul;281(1):G138-43. doi: 10.1152/ajpgi.2001.281.1.G138. PMID: 11408265

Prognosis

An observational study of the effects of smoking cessation earlier on the clinical characteristics and course of acute exacerbations of chronic obstructive pulmonary disease.
Li X, Wu Z, Xue M, Du W
BMC Pulm Med 2022 Oct 27;22(1):390. doi: 10.1186/s12890-022-02187-5. PMID: 36303160Free PMC Article
Colonic gas transit in patients with bloating: the effect of an electromechanical stimulator of the abdominal wall.
Tremolaterra F, Pascariello A, Gallotta S, Ciacci C, Iovino P
Tech Coloproctol 2013 Aug;17(4):405-10. Epub 2012 Dec 4 doi: 10.1007/s10151-012-0951-1. PMID: 23207715
Effect of high- and low-caloric mixed liquid meals on intestinal gas dynamics.
Harder H, Hernando-Harder AC, Franke A, Krammer HJ, Singer MV
Dig Dis Sci 2006 Jan;51(1):140-6. doi: 10.1007/s10620-006-3099-x. PMID: 16416227
Methods for decreasing postoperative gut dysmotility.
Miedema BW, Johnson JO
Lancet Oncol 2003 Jun;4(6):365-72. doi: 10.1016/s1470-2045(03)01118-5. PMID: 12788410
Linear programming analysis of VA/Q distributions: limits on central moments.
Kapitan KS, Wagner PD
J Appl Physiol (1985) 1986 May;60(5):1772-81. doi: 10.1152/jappl.1986.60.5.1772. PMID: 3011729

Clinical prediction guides

Physical activity and intestinal gas clearance in patients with bloating.
Villoria A, Serra J, Azpiroz F, Malagelada JR
Am J Gastroenterol 2006 Nov;101(11):2552-7. Epub 2006 Oct 4 doi: 10.1111/j.1572-0241.2006.00873.x. PMID: 17029608
Reflex control of intestinal gas dynamics and tolerance in humans.
Harder H, Serra J, Azpiroz F, Malagelada JR
Am J Physiol Gastrointest Liver Physiol 2004 Jan;286(1):G89-94. Epub 2003 Aug 28 doi: 10.1152/ajpgi.00174.2003. PMID: 12946941
Methods for decreasing postoperative gut dysmotility.
Miedema BW, Johnson JO
Lancet Oncol 2003 Jun;4(6):365-72. doi: 10.1016/s1470-2045(03)01118-5. PMID: 12788410
Gastric distension and duodenal lipid infusion modulate intestinal gas transit and tolerance in humans.
Serra J, Azpiroz F, Malagelada JR
Am J Gastroenterol 2002 Sep;97(9):2225-30. doi: 10.1111/j.1572-0241.2002.05976.x. PMID: 12358237
Mechanisms of intestinal gas retention in humans: impaired propulsion versus obstructed evacuation.
Serra J, Azpiroz F, Malagelada JR
Am J Physiol Gastrointest Liver Physiol 2001 Jul;281(1):G138-43. doi: 10.1152/ajpgi.2001.281.1.G138. PMID: 11408265

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