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Vesicle

MedGen UID:
568991
•Concept ID:
C0333262
•
Anatomical Abnormality
SNOMED CT: Vesicle (82515000)

Definition

A small (less than 1 cm) fluid-filled lesion, raised above the plane of surrounding skin [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVesicle

Professional guidelines

PubMed

MitoEVs: A new player in multiple disease pathology and treatment.
Zhou X, Liu S, Lu Y, Wan M, Cheng J, Liu J
J Extracell Vesicles 2023 Apr;12(4):e12320. doi: 10.1002/jev2.12320. PMID: 37002588Free PMC Article
Mesenchymal Stem Cell-Derived Extracellular Vesicles with High PD-L1 Expression for Autoimmune Diseases Treatment.
Xu F, Fei Z, Dai H, Xu J, Fan Q, Shen S, Zhang Y, Ma Q, Chu J, Peng F, Zhou F, Liu Z, Wang C
Adv Mater 2022 Jan;34(1):e2106265. Epub 2021 Oct 23 doi: 10.1002/adma.202106265. PMID: 34613627
Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum: A Delphi Consensus of International Experts.
Maverakis E, Ma C, Shinkai K, Fiorentino D, Callen JP, Wollina U, Marzano AV, Wallach D, Kim K, Schadt C, Ormerod A, Fung MA, Steel A, Patel F, Qin R, Craig F, Williams HC, Powell F, Merleev A, Cheng MY
JAMA Dermatol 2018 Apr 1;154(4):461-466. doi: 10.1001/jamadermatol.2017.5980. PMID: 29450466

Recent clinical studies

Etiology

Ferroportin-dependent ferroptosis induced by ellagic acid retards liver fibrosis by impairing the SNARE complexes formation.
Li L, Wang K, Jia R, Xie J, Ma L, Hao Z, Zhang W, Mo J, Ren F
Redox Biol 2022 Oct;56:102435. Epub 2022 Aug 23 doi: 10.1016/j.redox.2022.102435. PMID: 36029649Free PMC Article
Vesicle trafficking and lipid metabolism in synucleinopathy.
Fanning S, Selkoe D, Dettmer U
Acta Neuropathol 2021 Apr;141(4):491-510. Epub 2020 Jun 30 doi: 10.1007/s00401-020-02177-z. PMID: 32607605Free PMC Article
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins.
Miesenböck G, De Angelis DA, Rothman JE
Nature 1998 Jul 9;394(6689):192-5. doi: 10.1038/28190. PMID: 9671304
Phosphoinositide kinases.
Carpenter CL, Cantley LC
Curr Opin Cell Biol 1996 Apr;8(2):153-8. doi: 10.1016/s0955-0674(96)80060-3. PMID: 8791418
Cholinergic-specific glycoconjugates.
Whittaker VP, Kelić S
Neurochem Res 1995 Nov;20(11):1377-87. doi: 10.1007/BF00992514. PMID: 8786825

Diagnosis

SNARE-mediated vesicle navigation, vesicle anatomy and exocytotic fusion pore.
Zorec R
Cell Calcium 2018 Jul;73:53-54. Epub 2018 Mar 29 doi: 10.1016/j.ceca.2018.03.004. PMID: 29880197
Diagnosis and management of symptomatic seminal vesicle calculi.
Christodoulidou M, Parnham A, Nigam R
Scand J Urol 2017 Aug;51(4):237-244. Epub 2017 Mar 23 doi: 10.1080/21681805.2017.1295398. PMID: 28332431
Ectosomes and exosomes: shedding the confusion between extracellular vesicles.
Cocucci E, Meldolesi J
Trends Cell Biol 2015 Jun;25(6):364-72. Epub 2015 Feb 12 doi: 10.1016/j.tcb.2015.01.004. PMID: 25683921
Visualizing presynaptic function.
Kavalali ET, Jorgensen EM
Nat Neurosci 2014 Jan;17(1):10-6. Epub 2013 Dec 26 doi: 10.1038/nn.3578. PMID: 24369372
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.
Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC
Science 2010 Sep 24;329(5999):1663-7. Epub 2010 Aug 26 doi: 10.1126/science.1195227. PMID: 20798282Free PMC Article

Therapy

Effect of Verapamil on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial.
Forlenza GP, McVean J, Beck RW, Bauza C, Bailey R, Buckingham B, DiMeglio LA, Sherr JL, Clements M, Neyman A, Evans-Molina C, Sims EK, Messer LH, Ekhlaspour L, McDonough R, Van Name M, Rojas D, Beasley S, DuBose S, Kollman C, Moran A; CLVer Study Group
JAMA 2023 Mar 28;329(12):990-999. doi: 10.1001/jama.2023.2064. PMID: 36826844Free PMC Article
Effect of Tight Glycemic Control on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial.
McVean J, Forlenza GP, Beck RW, Bauza C, Bailey R, Buckingham B, DiMeglio LA, Sherr JL, Clements M, Neyman A, Evans-Molina C, Sims EK, Messer LH, Ekhlaspour L, McDonough R, Van Name M, Rojas D, Beasley S, DuBose S, Kollman C, Moran A; CLVer Study Group
JAMA 2023 Mar 28;329(12):980-989. doi: 10.1001/jama.2023.2063. PMID: 36826834Free PMC Article
Ferroportin-dependent ferroptosis induced by ellagic acid retards liver fibrosis by impairing the SNARE complexes formation.
Li L, Wang K, Jia R, Xie J, Ma L, Hao Z, Zhang W, Mo J, Ren F
Redox Biol 2022 Oct;56:102435. Epub 2022 Aug 23 doi: 10.1016/j.redox.2022.102435. PMID: 36029649Free PMC Article
Dyshidrosiform Bullous Pemphigoid.
Cohen PR
Medicina (Kaunas) 2021 Apr 20;57(4) doi: 10.3390/medicina57040398. PMID: 33924249Free PMC Article
Adjuvant radiotherapy versus early salvage radiotherapy following radical prostatectomy (TROG 08.03/ANZUP RAVES): a randomised, controlled, phase 3, non-inferiority trial.
Kneebone A, Fraser-Browne C, Duchesne GM, Fisher R, Frydenberg M, Herschtal A, Williams SG, Brown C, Delprado W, Haworth A, Joseph DJ, Martin JM, Matthews JHL, Millar JL, Sidhom M, Spry N, Tang CI, Turner S, Wiltshire KL, Woo HH, Davis ID, Lim TS, Pearse M
Lancet Oncol 2020 Oct;21(10):1331-1340. doi: 10.1016/S1470-2045(20)30456-3. PMID: 33002437

Prognosis

Genetic and Metabolic Neonatal Epilepsies.
Phitsanuwong C
Pediatr Ann 2021 Jun;50(6):e245-e253. Epub 2021 Jun 1 doi: 10.3928/19382359-20210518-01. PMID: 34115564
Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view.
Thietart S, Rautou PE
J Hepatol 2020 Dec;73(6):1507-1525. Epub 2020 Jul 15 doi: 10.1016/j.jhep.2020.07.014. PMID: 32682050
Extracellular vesicle cross-talk in the liposarcoma microenvironment.
Casadei L, Pollock RE
Cancer Lett 2020 Sep 1;487:27-33. Epub 2020 May 26 doi: 10.1016/j.canlet.2020.04.026. PMID: 32470489
Perimenopausal conception.
Tarlatzis BC, Zepiridis L
Ann N Y Acad Sci 2003 Nov;997:93-104. doi: 10.1196/annals.1290.011. PMID: 14644814
Adult urological sarcoma.
Russo P, Brady MS, Conlon K, Hajdu SI, Fair WR, Herr HW, Brennan MF
J Urol 1992 Apr;147(4):1032-6; discussion 1036-7. doi: 10.1016/s0022-5347(17)37456-6. PMID: 1552580

Clinical prediction guides

Plasma extracellular vesicle derived protein profile predicting and monitoring immunotherapeutic outcomes of gastric cancer.
Zhang C, Chong X, Jiang F, Gao J, Chen Y, Jia K, Fan M, Liu X, An J, Li J, Zhang X, Shen L
J Extracell Vesicles 2022 Apr;11(4):e12209. doi: 10.1002/jev2.12209. PMID: 35362262Free PMC Article
The extracellular vesicle generation paradox: a bacterial point of view.
McMillan HM, Kuehn MJ
EMBO J 2021 Nov 2;40(21):e108174. Epub 2021 Oct 11 doi: 10.15252/embj.2021108174. PMID: 34636061Free PMC Article
Reliable measurements of extracellular vesicles by clinical flow cytometry.
Kuiper M, van de Nes A, Nieuwland R, Varga Z, van der Pol E
Am J Reprod Immunol 2021 Feb;85(2):e13350. Epub 2020 Oct 8 doi: 10.1111/aji.13350. PMID: 32966654Free PMC Article
Emerging Technologies for the Diagnosis of Perihilar Cholangiocarcinoma.
Rizvi S, Eaton J, Yang JD, Chandrasekhara V, Gores GJ
Semin Liver Dis 2018 May;38(2):160-169. Epub 2018 Jun 5 doi: 10.1055/s-0038-1655775. PMID: 29871021Free PMC Article
Coronary Artery Calcification: From Mechanism to Molecular Imaging.
Nakahara T, Dweck MR, Narula N, Pisapia D, Narula J, Strauss HW
JACC Cardiovasc Imaging 2017 May;10(5):582-593. doi: 10.1016/j.jcmg.2017.03.005. PMID: 28473100

Recent systematic reviews

Extracellular vesicle biomarkers for prostate cancer diagnosis: A systematic review and meta-analysis.
Li Y, Shi X, Jia E, Qin S, Yu F
Urol Oncol 2023 Nov;41(11):440-453. Epub 2023 Oct 30 doi: 10.1016/j.urolonc.2023.08.019. PMID: 37914569
Head-to-head Comparison of the Diagnostic Accuracy of Prostate-specific Membrane Antigen Positron Emission Tomography and Conventional Imaging Modalities for Initial Staging of Intermediate- to High-risk Prostate Cancer: A Systematic Review and Meta-analysis.
Chow KM, So WZ, Lee HJ, Lee A, Yap DWT, Takwoingi Y, Tay KJ, Tuan J, Thang SP, Lam W, Yuen J, Lawrentschuk N, Hofman MS, Murphy DG, Chen K
Eur Urol 2023 Jul;84(1):36-48. Epub 2023 Apr 7 doi: 10.1016/j.eururo.2023.03.001. PMID: 37032189
Extracellular vesicle biomarkers for pancreatic cancer diagnosis: a systematic review and meta-analysis.
Jia E, Ren N, Shi X, Zhang R, Yu H, Yu F, Qin S, Xue J
BMC Cancer 2022 May 23;22(1):573. doi: 10.1186/s12885-022-09463-x. PMID: 35606727Free PMC Article
Solitary Fibrous Tumor of the Seminal Vesicle: A Systematic Literature Review and Case Presentation.
Crocetti D, Sapienza P, Lamazza A, DE Felice F, Brachini G, Desiato E, Mingoli A, Fiori E, DE Cesare A
In Vivo 2021 Jul-Aug;35(4):1945-1950. doi: 10.21873/invivo.12461. PMID: 34182467Free PMC Article
Diagnosis and management of symptomatic seminal vesicle calculi.
Christodoulidou M, Parnham A, Nigam R
Scand J Urol 2017 Aug;51(4):237-244. Epub 2017 Mar 23 doi: 10.1080/21681805.2017.1295398. PMID: 28332431

Supplemental Content

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