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Diverticulosis of trachea

MedGen UID:
573615
•Concept ID:
C0340213
•
Disease or Syndrome
Synonyms: tracheal diverticulosis; tracheal diverticulum disease; tracheal diverticulum syndrome
SNOMED CT: Tracheal diverticulum (14011008); Tracheal diverticulosis (14011008)
 
HPO: HP:0006509

Definition

Tracheal diverticula are blind-ended outpouchings arising from the trachea. They are usually an incidental finding. Occasionally they can mimic pneumomediastinum. Tracheal diverticula are either congenital or acquired, in the latter case the most common causes are prolonged increased intraluminal pressure, e.g. chronic cough, COPD, tracheomalacia, and iatrogenic (e.g. post-surgical). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiverticulosis of trachea

Conditions with this feature

Congenital tracheobronchomegaly
MedGen UID:
11871
•Concept ID:
C0040587
•
Disease or Syndrome
Tracheobronchiomegaly is characterized by striking dilatation of the intrathoracic trachea and of the major bronchi (summary by Johnston and Green, 1965).
See: Condition Record
Congenital tracheobronchomegaly

Professional guidelines

PubMed

The role of MRI in the diagnosis and management of tracheal diverticulum.
Zhang Y, Tan Y, Chen J, Fang C
BMC Med Imaging 2022 Apr 22;22(1):74. doi: 10.1186/s12880-022-00802-9. PMID: 35448959Free PMC Article
Congenital tracheal diverticulum: from clinical aspects to treatment.
Mangiameli G, Alzreibi C, Arame A, LE Pimpec-Barthes F
Minerva Surg 2021 Feb;76(1):101-102. Epub 2020 Aug 6 doi: 10.23736/S2724-5691.20.08446-1. PMID: 32773754
Management of symptomatic tracheal pouches.
Johnson LB, Cotton RT, Rutter MJ
Int J Pediatr Otorhinolaryngol 2007 Apr;71(4):527-31. Epub 2007 Feb 6 doi: 10.1016/j.ijporl.2006.10.024. PMID: 17289165

Recent clinical studies

Etiology

Post-operative Outcomes for Vascular Rings: A Systematic Review and Meta-analysis.
Rato J, Zidere V, François K, Boon M, Depypere A, Simpson JM, Speggiorin S, Vigneswaran TV
J Pediatr Surg 2023 Sep;58(9):1744-1753. Epub 2023 Feb 28 doi: 10.1016/j.jpedsurg.2023.02.058. PMID: 36967253
The role of MRI in the diagnosis and management of tracheal diverticulum.
Zhang Y, Tan Y, Chen J, Fang C
BMC Med Imaging 2022 Apr 22;22(1):74. doi: 10.1186/s12880-022-00802-9. PMID: 35448959Free PMC Article
Vascular Rings With Tracheoesophageal Compression: Management Considerations.
Backer CL
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2020;23:48-52. doi: 10.1053/j.pcsu.2020.02.004. PMID: 32354547
Double Aortic Arch With Kommerell Diverticulum.
Backer CL, Bharadwaj SN, Eltayeb OM, Forbess JM, Popescu AR, Mongé MC
Ann Thorac Surg 2019 Jul;108(1):161-166. Epub 2019 Mar 5 doi: 10.1016/j.athoracsur.2019.01.062. PMID: 30849335
Categorization and repair of recurrent and acquired tracheoesophageal fistulae occurring after esophageal atresia repair.
Smithers CJ, Hamilton TE, Manfredi MA, Rhein L, Ngo P, Gallagher D, Foker JE, Jennings RW
J Pediatr Surg 2017 Mar;52(3):424-430. Epub 2016 Aug 31 doi: 10.1016/j.jpedsurg.2016.08.012. PMID: 27616617

Diagnosis

Rings and Slings: Not Such Simple Things.
Ruiz-Solano E, Mitchell M
Curr Cardiol Rep 2022 Oct;24(10):1495-1503. Epub 2022 Oct 3 doi: 10.1007/s11886-022-01764-8. PMID: 36190599Free PMC Article
Vascular rings.
Worhunsky DJ, Levy BE, Stephens EH, Backer CL
Semin Pediatr Surg 2021 Dec;30(6):151128. Epub 2021 Oct 23 doi: 10.1016/j.sempedsurg.2021.151128. PMID: 34930596
Vascular rings.
Backer CL, Mongé MC, Popescu AR, Eltayeb OM, Rastatter JC, Rigsby CK
Semin Pediatr Surg 2016 Jun;25(3):165-75. Epub 2016 Feb 22 doi: 10.1053/j.sempedsurg.2016.02.009. PMID: 27301603
Tracheal Diverticula.
Gayer G
Semin Ultrasound CT MR 2016 Jun;37(3):190-5. Epub 2016 Apr 8 doi: 10.1053/j.sult.2016.04.002. PMID: 27261344
Mounier-Kuhn syndrome.
Simon M, Vremaroiu P, Andrei F
J Bronchology Interv Pulmonol 2014 Apr;21(2):145-9. doi: 10.1097/LBR.0000000000000068. PMID: 24739689

Therapy

Posterior tracheal diverticulum: a case report.
Safarian A, Karimi M, Deravi N, Naseri R, Agin K
J Med Case Rep 2024 Oct 31;18(1):511. doi: 10.1186/s13256-024-04851-2. PMID: 39478593Free PMC Article
Perioperative and Anesthetic Considerations in Vascular Rings and Slings.
Wadle M, Joffe D, Backer C, Ross F
Semin Cardiothorac Vasc Anesth 2024 Sep;28(3):152-164. Epub 2024 Feb 20 doi: 10.1177/10892532241234404. PMID: 38379198
Post-operative Outcomes for Vascular Rings: A Systematic Review and Meta-analysis.
Rato J, Zidere V, François K, Boon M, Depypere A, Simpson JM, Speggiorin S, Vigneswaran TV
J Pediatr Surg 2023 Sep;58(9):1744-1753. Epub 2023 Feb 28 doi: 10.1016/j.jpedsurg.2023.02.058. PMID: 36967253
Total arch replacement and frozen elephant trunk for aortic dissection in aberrant right subclavian artery.
Li JR, Ma WG, Chen Y, Zhu JM, Zheng J, Xu SD, Liu YM, Sun LZ
Eur J Cardiothorac Surg 2020 Jul 1;58(1):104-111. doi: 10.1093/ejcts/ezaa029. PMID: 32057078
Categorization and repair of recurrent and acquired tracheoesophageal fistulae occurring after esophageal atresia repair.
Smithers CJ, Hamilton TE, Manfredi MA, Rhein L, Ngo P, Gallagher D, Foker JE, Jennings RW
J Pediatr Surg 2017 Mar;52(3):424-430. Epub 2016 Aug 31 doi: 10.1016/j.jpedsurg.2016.08.012. PMID: 27616617

Prognosis

An aberrant right subclavian artery in a 63-year-old male cadaver.
Ostrowski P, Bonczar M, Przybycień W, Zamojska I, Kołodziejczyk B, Walocha J, Koziej M
Folia Morphol (Warsz) 2023;82(3):726-731. Epub 2022 Sep 30 doi: 10.5603/FM.a2022.0085. PMID: 36178279
Rings and Slings: Not Such Simple Things.
Ruiz-Solano E, Mitchell M
Curr Cardiol Rep 2022 Oct;24(10):1495-1503. Epub 2022 Oct 3 doi: 10.1007/s11886-022-01764-8. PMID: 36190599Free PMC Article
Total arch replacement and frozen elephant trunk for aortic dissection in aberrant right subclavian artery.
Li JR, Ma WG, Chen Y, Zhu JM, Zheng J, Xu SD, Liu YM, Sun LZ
Eur J Cardiothorac Surg 2020 Jul 1;58(1):104-111. doi: 10.1093/ejcts/ezaa029. PMID: 32057078
The aberrant right subclavian artery: cadaveric study and literature review.
Natsis K, Didagelos M, Gkiouliava A, Lazaridis N, Vyzas V, Piagkou M
Surg Radiol Anat 2017 May;39(5):559-565. Epub 2016 Dec 20 doi: 10.1007/s00276-016-1796-5. PMID: 27999944
Acquired benign esophago-airway fistulas.
Cherveniakov A, Tzekov C, Grigorov GE, Cherveniakov P
Eur J Cardiothorac Surg 1996;10(9):713-6. doi: 10.1016/s1010-7940(96)80329-0. PMID: 8905271

Clinical prediction guides

Five cases of endoscopically noted esophageal stenosis due to abnormal aortic angiogenesis.
Iwanaga S, Inomata H, Tabuchi M, Sasaki R, Yamaguchi N, Nakao K
Clin J Gastroenterol 2023 Jun;16(3):325-329. Epub 2023 Feb 23 doi: 10.1007/s12328-023-01773-2. PMID: 36821066
Total arch replacement and frozen elephant trunk for aortic dissection in aberrant right subclavian artery.
Li JR, Ma WG, Chen Y, Zhu JM, Zheng J, Xu SD, Liu YM, Sun LZ
Eur J Cardiothorac Surg 2020 Jul 1;58(1):104-111. doi: 10.1093/ejcts/ezaa029. PMID: 32057078
Hybrid Treatment of the Aberrant Right Subclavian Artery (Arteria Lusoria): Feasibility Study on 180 Angio-CTs.
Settembre N, Saba C, Bouziane Z, Jeannon F, Mandry D, Malikov S
Ann Vasc Surg 2017 Oct;44:229-233. Epub 2017 May 9 doi: 10.1016/j.avsg.2017.03.172. PMID: 28495534
Mounier-Kuhn syndrome.
Simon M, Vremaroiu P, Andrei F
J Bronchology Interv Pulmonol 2014 Apr;21(2):145-9. doi: 10.1097/LBR.0000000000000068. PMID: 24739689
Tracheal and main bronchial diverticula: the role of CT.
Polverosi R, Carloni A, Poletti V
Radiol Med 2008 Mar;113(2):181-9. Epub 2008 Apr 2 doi: 10.1007/s11547-008-0249-6. PMID: 18386120

Recent systematic reviews

Post-operative Outcomes for Vascular Rings: A Systematic Review and Meta-analysis.
Rato J, Zidere V, François K, Boon M, Depypere A, Simpson JM, Speggiorin S, Vigneswaran TV
J Pediatr Surg 2023 Sep;58(9):1744-1753. Epub 2023 Feb 28 doi: 10.1016/j.jpedsurg.2023.02.058. PMID: 36967253
Congenital Anomalies of the Tracheobronchial Tree: A Meta-Analysis and Clinical Considerations.
Wong LM, Cheruiyot I, de Oliveira MHS, Keet K, Tomaszewski KA, Walocha JA, Tubbs S, Henry BM
Ann Thorac Surg 2021 Jul;112(1):315-325. Epub 2020 Nov 4 doi: 10.1016/j.athoracsur.2020.08.060. PMID: 33159867

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