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Hyperplasia of Brunner glands of duodenum

MedGen UID:
574271
Concept ID:
C0341253
Disease or Syndrome
Synonyms: Brunner gland hyperplasia; Brunner's gland hyperplasia; Brunner's Gland Hyperplasia
SNOMED CT: Brunner gland hyperplasia (235700007); Brunner's gland hyperplasia (235700007); Hyperplasia of Brunner glands of duodenum (235700007)

Definition

A rare hyperplastic lesion of Brunner''s gland in the duodenum. Although it is usually asymptomatic and discovered incidentally during upper gastrointestinal endoscopy, it may cause hemorrhage. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyperplasia of Brunner glands of duodenum

Professional guidelines

PubMed

Pavlovic Markovic A, Rösch T, Alempijevic T, Krstic M, Tomic D, Dugalic P, Sokic Milutinovic A, Bulajic M
Ultraschall Med 2012 Dec;33(7):E210-E217. Epub 2012 Nov 5 doi: 10.1055/s-0032-1313135. PMID: 23129520
Reddy RR, Schuman BM, Priest RJ
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Recent clinical studies

Etiology

Zhu M, Li H, Wu Y, An Y, Wang Y, Ye C, Zhang D, Ma R, Wang X, Shao X, Guo X, Qi X
Adv Ther 2021 Jun;38(6):2779-2794. Epub 2021 Apr 29 doi: 10.1007/s12325-021-01750-6. PMID: 33914269Free PMC Article
Destek S, Gul VO
Can J Gastroenterol Hepatol 2019;2019:6340565. Epub 2019 May 2 doi: 10.1155/2019/6340565. PMID: 31187029Free PMC Article
Stoven SA, Choung RS, Rubio-Tapia A, Absah I, Lam-Himlin DM, Harris LA, Ngamruengphong S, Vazquez Roque MI, Wu TT, Murray JA
Clin Gastroenterol Hepatol 2016 Nov;14(11):1582-1588. Epub 2016 Mar 7 doi: 10.1016/j.cgh.2016.02.026. PMID: 26965842
Stolte M, Sticht T, Eidt S, Ebert D, Finkenzeller G
Endoscopy 1994 Oct;26(8):659-65. doi: 10.1055/s-2007-1009061. PMID: 7859674
Fuse Y, Tsuchihashi Y, Takamasu M, Kodama T, Fujita S, Kashima K
Scand J Gastroenterol 1990 Feb;25(2):165-72. doi: 10.3109/00365529009107939. PMID: 2305213

Diagnosis

Aparicio-López D, Cuadal Marzo J, Ollero Domenche L, Abecia Martínez EI, Hörndler Argárate C, Cantín Blázquez S, Cerdán Pascual R, Ligorred Padilla LA
Rev Esp Enferm Dig 2023 Nov;115(11):661-662. doi: 10.17235/reed.2023.9538/2023. PMID: 36896921
Zhu M, Li H, Wu Y, An Y, Wang Y, Ye C, Zhang D, Ma R, Wang X, Shao X, Guo X, Qi X
Adv Ther 2021 Jun;38(6):2779-2794. Epub 2021 Apr 29 doi: 10.1007/s12325-021-01750-6. PMID: 33914269Free PMC Article
Ortiz Requena D, Rojas C, Garcia-Buitrago M
Diagn Cytopathol 2021 Jun;49(6):E222-E225. Epub 2020 Dec 12 doi: 10.1002/dc.24680. PMID: 33314802
Destek S, Gul VO
Can J Gastroenterol Hepatol 2019;2019:6340565. Epub 2019 May 2 doi: 10.1155/2019/6340565. PMID: 31187029Free PMC Article
Franzin G, Musola R, Ghidini O, Manfrini C, Fratton A
Gastrointest Endosc 1985 Dec;31(6):374-8. doi: 10.1016/s0016-5107(85)72251-1. PMID: 4076734

Therapy

Yzet C, Lafeuille P, Pelascini E, Rivory J, Hervieu V, Pioche M
Endoscopy 2023 Dec;55(S 01):E942-E943. Epub 2023 Aug 21 doi: 10.1055/a-2134-9501. PMID: 37604435Free PMC Article
Sande-Lemos Azcue MP, Shaoul R, Cutz E, Sherman PM
J Pediatr Gastroenterol Nutr 1998 Oct;27(4):452-6. doi: 10.1097/00005176-199810000-00018. PMID: 9779978
Franzin G, Musola R, Mencarelli R
Histopathology 1982 Jul;6(4):429-37. doi: 10.1111/j.1365-2559.1982.tb02740.x. PMID: 7118082
Franzin G, Musola R, Mencarelli R
Histopathology 1982 Jul;6(4):439-49. doi: 10.1111/j.1365-2559.1982.tb02741.x. PMID: 6749640
Spellberg MA, Vucelic B
Am J Gastroenterol 1980 Jun;73(6):519-22. PMID: 7424875

Prognosis

Zhu M, Li H, Wu Y, An Y, Wang Y, Ye C, Zhang D, Ma R, Wang X, Shao X, Guo X, Qi X
Adv Ther 2021 Jun;38(6):2779-2794. Epub 2021 Apr 29 doi: 10.1007/s12325-021-01750-6. PMID: 33914269Free PMC Article
El Faleh I, Lutz N, Osterheld MC, Reinberg O, Nydegger A
J Pediatr Surg 2009 Apr;44(4):E21-4. doi: 10.1016/j.jpedsurg.2009.01.075. PMID: 19361619
Kurella RR, Ancha HR, Hussain S, Lightfoot SA, Harty R
South Med J 2008 Jun;101(6):648-50. doi: 10.1097/SMJ.0b013e318172435a. PMID: 18475238
Kushima R, Stolte M, Dirks K, Vieth M, Okabe H, Borchard F, Hattori T
Virchows Arch 2002 Jun;440(6):655-9. Epub 2002 Feb 21 doi: 10.1007/s00428-002-0615-z. PMID: 12070607
Farkas IE, Gerö G
Acta Physiol Hung 1989;73(2-3):257-60. PMID: 2596316

Clinical prediction guides

Stoven SA, Choung RS, Rubio-Tapia A, Absah I, Lam-Himlin DM, Harris LA, Ngamruengphong S, Vazquez Roque MI, Wu TT, Murray JA
Clin Gastroenterol Hepatol 2016 Nov;14(11):1582-1588. Epub 2016 Mar 7 doi: 10.1016/j.cgh.2016.02.026. PMID: 26965842
Kim K, Jang SJ, Song HJ, Yu E
Dig Dis Sci 2013 Jan;58(1):194-201. Epub 2012 Jul 27 doi: 10.1007/s10620-012-2320-3. PMID: 22836185
Terada T
Int J Clin Exp Pathol 2012;5(1):46-51. Epub 2012 Jan 1 PMID: 22295146Free PMC Article
Merine D, Jones B, Ghahremani GG, Hamilton SR, Bayless TM
Gastrointest Radiol 1991 Spring;16(2):104-8. doi: 10.1007/BF01887320. PMID: 2016018
Fuse Y, Tsuchihashi Y, Takamasu M, Kodama T, Fujita S, Kashima K
Scand J Gastroenterol 1990 Feb;25(2):165-72. doi: 10.3109/00365529009107939. PMID: 2305213

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