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Insulin-resistance syndrome type B

MedGen UID:
574967
•Concept ID:
C0342337
•
Disease or Syndrome
Synonyms: Insulin resistance - type B; insulin-resistance syndrome type B; insulin-resistance type B
SNOMED CT: Insulin resistance - type B (237652003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0016464
Orphanet: ORPHA2298

Definition

A rare genetic disease that belongs to the group of extreme insulin-resistance syndromes and is due to autoantibodies directed against insulin receptor. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInsulin-resistance syndrome type B
Follow this link to review classifications for Insulin-resistance syndrome type B in Orphanet.

Professional guidelines

PubMed

New classification and diagnostic criteria for insulin resistance syndrome.
Ogawa W, Araki E, Ishigaki Y, Hirota Y, Maegawa H, Yamauchi T, Yorifuji T, Katagiri H
Endocr J 2022 Feb 28;69(2):107-113. Epub 2022 Feb 1 doi: 10.1507/endocrj.EJ21-0725. PMID: 35110500

Recent clinical studies

Etiology

New classification and diagnostic criteria for insulin resistance syndrome.
Ogawa W, Araki E, Ishigaki Y, Hirota Y, Maegawa H, Yamauchi T, Yorifuji T, Katagiri H
Endocr J 2022 Feb 28;69(2):107-113. Epub 2022 Feb 1 doi: 10.1507/endocrj.EJ21-0725. PMID: 35110500
The Effect of Dietary Fibre on Gut Microbiota, Lipid Profile, and Inflammatory Markers in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
Ojo O, Ojo OO, Zand N, Wang X
Nutrients 2021 May 26;13(6) doi: 10.3390/nu13061805. PMID: 34073366Free PMC Article
Nonalcoholic fatty liver disease as a metabolic disease in humans: A literature review.
Cariou B, Byrne CD, Loomba R, Sanyal AJ
Diabetes Obes Metab 2021 May;23(5):1069-1083. Epub 2021 Feb 10 doi: 10.1111/dom.14322. PMID: 33464677Free PMC Article
Epidemiology of Hepatocellular Carcinoma.
McGlynn KA, Petrick JL, El-Serag HB
Hepatology 2021 Jan;73 Suppl 1(Suppl 1):4-13. Epub 2020 Nov 24 doi: 10.1002/hep.31288. PMID: 32319693Free PMC Article
The Vasculature in Prediabetes.
Wasserman DH, Wang TJ, Brown NJ
Circ Res 2018 Apr 13;122(8):1135-1150. doi: 10.1161/CIRCRESAHA.118.311912. PMID: 29650631Free PMC Article

Diagnosis

New classification and diagnostic criteria for insulin resistance syndrome.
Ogawa W, Araki E, Ishigaki Y, Hirota Y, Maegawa H, Yamauchi T, Yorifuji T, Katagiri H
Endocr J 2022 Feb 28;69(2):107-113. Epub 2022 Feb 1 doi: 10.1507/endocrj.EJ21-0725. PMID: 35110500
Nonalcoholic fatty liver disease as a metabolic disease in humans: A literature review.
Cariou B, Byrne CD, Loomba R, Sanyal AJ
Diabetes Obes Metab 2021 May;23(5):1069-1083. Epub 2021 Feb 10 doi: 10.1111/dom.14322. PMID: 33464677Free PMC Article
Epidemiology of Hepatocellular Carcinoma.
McGlynn KA, Petrick JL, El-Serag HB
Hepatology 2021 Jan;73 Suppl 1(Suppl 1):4-13. Epub 2020 Nov 24 doi: 10.1002/hep.31288. PMID: 32319693Free PMC Article
Cardiac natriuretic peptides.
Goetze JP, Bruneau BG, Ramos HR, Ogawa T, de Bold MK, de Bold AJ
Nat Rev Cardiol 2020 Nov;17(11):698-717. Epub 2020 May 22 doi: 10.1038/s41569-020-0381-0. PMID: 32444692
Metabolites as regulators of insulin sensitivity and metabolism.
Yang Q, Vijayakumar A, Kahn BB
Nat Rev Mol Cell Biol 2018 Oct;19(10):654-672. doi: 10.1038/s41580-018-0044-8. PMID: 30104701Free PMC Article

Therapy

Dual GIP and GLP-1 Receptor Agonist Tirzepatide Improves Beta-cell Function and Insulin Sensitivity in Type 2 Diabetes.
Thomas MK, Nikooienejad A, Bray R, Cui X, Wilson J, Duffin K, Milicevic Z, Haupt A, Robins DA
J Clin Endocrinol Metab 2021 Jan 23;106(2):388-396. doi: 10.1210/clinem/dgaa863. PMID: 33236115Free PMC Article
Epidemiology of Hepatocellular Carcinoma.
McGlynn KA, Petrick JL, El-Serag HB
Hepatology 2021 Jan;73 Suppl 1(Suppl 1):4-13. Epub 2020 Nov 24 doi: 10.1002/hep.31288. PMID: 32319693Free PMC Article
The dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist, tirzepatide, improves lipoprotein biomarkers associated with insulin resistance and cardiovascular risk in patients with type 2 diabetes.
Wilson JM, Nikooienejad A, Robins DA, Roell WC, Riesmeyer JS, Haupt A, Duffin KL, Taskinen MR, Ruotolo G
Diabetes Obes Metab 2020 Dec;22(12):2451-2459. Epub 2020 Sep 15 doi: 10.1111/dom.14174. PMID: 33462955Free PMC Article
Dietary patterns and management of type 2 diabetes: A systematic review of randomised clinical trials.
Papamichou D, Panagiotakos DB, Itsiopoulos C
Nutr Metab Cardiovasc Dis 2019 Jun;29(6):531-543. Epub 2019 Feb 25 doi: 10.1016/j.numecd.2019.02.004. PMID: 30952576
Low-Dose Methotrexate for the Prevention of Atherosclerotic Events.
Ridker PM, Everett BM, Pradhan A, MacFadyen JG, Solomon DH, Zaharris E, Mam V, Hasan A, Rosenberg Y, Iturriaga E, Gupta M, Tsigoulis M, Verma S, Clearfield M, Libby P, Goldhaber SZ, Seagle R, Ofori C, Saklayen M, Butman S, Singh N, Le May M, Bertrand O, Johnston J, Paynter NP, Glynn RJ; CIRT Investigators
N Engl J Med 2019 Feb 21;380(8):752-762. Epub 2018 Nov 10 doi: 10.1056/NEJMoa1809798. PMID: 30415610Free PMC Article

Prognosis

Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective.
Kumariya S, Ubba V, Jha RK, Gayen JR
Autophagy 2021 Oct;17(10):2706-2733. Epub 2021 Jun 23 doi: 10.1080/15548627.2021.1938914. PMID: 34161185Free PMC Article
Dual GIP and GLP-1 Receptor Agonist Tirzepatide Improves Beta-cell Function and Insulin Sensitivity in Type 2 Diabetes.
Thomas MK, Nikooienejad A, Bray R, Cui X, Wilson J, Duffin K, Milicevic Z, Haupt A, Robins DA
J Clin Endocrinol Metab 2021 Jan 23;106(2):388-396. doi: 10.1210/clinem/dgaa863. PMID: 33236115Free PMC Article
Epidemiology of Hepatocellular Carcinoma.
McGlynn KA, Petrick JL, El-Serag HB
Hepatology 2021 Jan;73 Suppl 1(Suppl 1):4-13. Epub 2020 Nov 24 doi: 10.1002/hep.31288. PMID: 32319693Free PMC Article
Cardiac natriuretic peptides.
Goetze JP, Bruneau BG, Ramos HR, Ogawa T, de Bold MK, de Bold AJ
Nat Rev Cardiol 2020 Nov;17(11):698-717. Epub 2020 May 22 doi: 10.1038/s41569-020-0381-0. PMID: 32444692
The Genetic Epidemiology of Type 2 Diabetes: Opportunities for Health Translation.
Meigs JB
Curr Diab Rep 2019 Jul 22;19(8):62. doi: 10.1007/s11892-019-1173-y. PMID: 31332628Free PMC Article

Clinical prediction guides

Spatial mapping reveals human adipocyte subpopulations with distinct sensitivities to insulin.
Bäckdahl J, Franzén L, Massier L, Li Q, Jalkanen J, Gao H, Andersson A, Bhalla N, Thorell A, Rydén M, Ståhl PL, Mejhert N
Cell Metab 2021 Sep 7;33(9):1869-1882.e6. Epub 2021 Aug 10 doi: 10.1016/j.cmet.2021.07.018. PMID: 34380013
Nonalcoholic fatty liver disease as a metabolic disease in humans: A literature review.
Cariou B, Byrne CD, Loomba R, Sanyal AJ
Diabetes Obes Metab 2021 May;23(5):1069-1083. Epub 2021 Feb 10 doi: 10.1111/dom.14322. PMID: 33464677Free PMC Article
The dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist, tirzepatide, improves lipoprotein biomarkers associated with insulin resistance and cardiovascular risk in patients with type 2 diabetes.
Wilson JM, Nikooienejad A, Robins DA, Roell WC, Riesmeyer JS, Haupt A, Duffin KL, Taskinen MR, Ruotolo G
Diabetes Obes Metab 2020 Dec;22(12):2451-2459. Epub 2020 Sep 15 doi: 10.1111/dom.14174. PMID: 33462955Free PMC Article
Association of insulin resistance and β-cell dysfunction with incident diabetes among adults in China: a nationwide, population-based, prospective cohort study.
Wang T, Lu J, Shi L, Chen G, Xu M, Xu Y, Su Q, Mu Y, Chen L, Hu R, Tang X, Yu X, Li M, Zhao Z, Chen Y, Yan L, Qin G, Wan Q, Dai M, Zhang D, Gao Z, Wang G, Shen F, Luo Z, Qin Y, Chen L, Huo Y, Li Q, Ye Z, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Zhao J, Lai S, Bi Y, DeFronzo RA, Wang W, Ning G; China Cardiometabolic Disease and Cancer Cohort Study Group
Lancet Diabetes Endocrinol 2020 Feb;8(2):115-124. Epub 2019 Dec 23 doi: 10.1016/S2213-8587(19)30425-5. PMID: 31879247
The Genetic Epidemiology of Type 2 Diabetes: Opportunities for Health Translation.
Meigs JB
Curr Diab Rep 2019 Jul 22;19(8):62. doi: 10.1007/s11892-019-1173-y. PMID: 31332628Free PMC Article

Recent systematic reviews

The Effect of Dietary Fibre on Gut Microbiota, Lipid Profile, and Inflammatory Markers in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
Ojo O, Ojo OO, Zand N, Wang X
Nutrients 2021 May 26;13(6) doi: 10.3390/nu13061805. PMID: 34073366Free PMC Article
Nonalcoholic fatty liver disease as a metabolic disease in humans: A literature review.
Cariou B, Byrne CD, Loomba R, Sanyal AJ
Diabetes Obes Metab 2021 May;23(5):1069-1083. Epub 2021 Feb 10 doi: 10.1111/dom.14322. PMID: 33464677Free PMC Article
Fatty acids, epigenetic mechanisms and chronic diseases: a systematic review.
González-Becerra K, Ramos-Lopez O, Barrón-Cabrera E, Riezu-Boj JI, Milagro FI, Martínez-López E, Martínez JA
Lipids Health Dis 2019 Oct 15;18(1):178. doi: 10.1186/s12944-019-1120-6. PMID: 31615571Free PMC Article
Dietary patterns and management of type 2 diabetes: A systematic review of randomised clinical trials.
Papamichou D, Panagiotakos DB, Itsiopoulos C
Nutr Metab Cardiovasc Dis 2019 Jun;29(6):531-543. Epub 2019 Feb 25 doi: 10.1016/j.numecd.2019.02.004. PMID: 30952576
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA, Hlatky MA, Jones DW, Lloyd-Jones D, Lopez-Pajares N, Ndumele CE, Orringer CE, Peralta CA, Saseen JJ, Smith SC Jr, Sperling L, Virani SS, Yeboah J
Circulation 2019 Jun 18;139(25):e1082-e1143. Epub 2018 Nov 10 doi: 10.1161/CIR.0000000000000625. PMID: 30586774Free PMC Article

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