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Early menarche

MedGen UID:
575096
•Concept ID:
C0342548
•
Finding
Synonyms: Precocious menstruation; Premature Menarche; Premature menarche
SNOMED CT: Precocious menstruation (44062003); Premature menarche (44062003); Early menarche (44062003)

Definition

Occurrence of the first menstrual period in a female before the usual or expected age. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEarly menarche

Professional guidelines

PubMed

EMAS position statement: Predictors of premature and early natural menopause.
Mishra GD, Chung HF, Cano A, Chedraui P, Goulis DG, Lopes P, Mueck A, Rees M, Senturk LM, Simoncini T, Stevenson JC, Stute P, Tuomikoski P, Lambrinoudaki I
Maturitas 2019 May;123:82-88. Epub 2019 Mar 13 doi: 10.1016/j.maturitas.2019.03.008. PMID: 31027683
Diagnosis and Management of Endometrial Cancer.
Braun MM, Overbeek-Wager EA, Grumbo RJ
Am Fam Physician 2016 Mar 15;93(6):468-74. PMID: 26977831
Pros and cons of GnRHa treatment for early puberty in girls.
Willemsen RH, Elleri D, Williams RM, Ong KK, Dunger DB
Nat Rev Endocrinol 2014 Jun;10(6):352-63. Epub 2014 Apr 8 doi: 10.1038/nrendo.2014.40. PMID: 24709660

Recent clinical studies

Etiology

Association between the reproductive health of young women and cardiovascular disease in later life: umbrella review.
Okoth K, Chandan JS, Marshall T, Thangaratinam S, Thomas GN, Nirantharakumar K, Adderley NJ
BMJ 2020 Oct 7;371:m3502. doi: 10.1136/bmj.m3502. PMID: 33028606Free PMC Article
A Review of the Epidemiology of Breast Cancer in Asia: Focus on Risk Factors.
Youn HJ, Han W
Asian Pac J Cancer Prev 2020 Apr 1;21(4):867-880. doi: 10.31557/APJCP.2020.21.4.867. PMID: 32334446Free PMC Article
EMAS position statement: Predictors of premature and early natural menopause.
Mishra GD, Chung HF, Cano A, Chedraui P, Goulis DG, Lopes P, Mueck A, Rees M, Senturk LM, Simoncini T, Stevenson JC, Stute P, Tuomikoski P, Lambrinoudaki I
Maturitas 2019 May;123:82-88. Epub 2019 Mar 13 doi: 10.1016/j.maturitas.2019.03.008. PMID: 31027683
Early menarche, nulliparity and the risk for premature and early natural menopause.
Mishra GD, Pandeya N, Dobson AJ, Chung HF, Anderson D, Kuh D, Sandin S, Giles GG, Bruinsma F, Hayashi K, Lee JS, Mizunuma H, Cade JE, Burley V, Greenwood DC, Goodman A, Simonsen MK, Adami HO, Demakakos P, Weiderpass E
Hum Reprod 2017 Mar 1;32(3):679-686. doi: 10.1093/humrep/dew350. PMID: 28119483Free PMC Article
Diagnosis and Management of Endometrial Cancer.
Braun MM, Overbeek-Wager EA, Grumbo RJ
Am Fam Physician 2016 Mar 15;93(6):468-74. PMID: 26977831

Diagnosis

Clinical Implications for Women of a Low-Carbohydrate or Ketogenic Diet With Intermittent Fasting.
Arbour MW, Stec M, Walker KC, Wika JC
Nurs Womens Health 2021 Apr;25(2):139-151. doi: 10.1016/j.nwh.2021.01.009. PMID: 33838849
A Review of the Epidemiology of Breast Cancer in Asia: Focus on Risk Factors.
Youn HJ, Han W
Asian Pac J Cancer Prev 2020 Apr 1;21(4):867-880. doi: 10.31557/APJCP.2020.21.4.867. PMID: 32334446Free PMC Article
Hormonal cytology.
Jaroslava D, Jana S
Cesk Patol 2019 Spring;55(2):96-106. PMID: 31181942
Diagnosis and Management of Endometrial Cancer.
Braun MM, Overbeek-Wager EA, Grumbo RJ
Am Fam Physician 2016 Mar 15;93(6):468-74. PMID: 26977831
Endometriosis in teenagers.
Sarıdoğan E
Womens Health (Lond) 2015 Aug;11(5):705-9. Epub 2015 Aug 28 doi: 10.2217/whe.15.58. PMID: 26315257

Therapy

Diet and Nutrients Intakes during Infancy and Childhood in Relation to Early Puberty: A Systematic Review and Meta-Analysis.
Tang J, Xue P, Huang X, Lin C, Liu S
Nutrients 2022 Nov 24;14(23) doi: 10.3390/nu14235004. PMID: 36501034Free PMC Article
Clinical Implications for Women of a Low-Carbohydrate or Ketogenic Diet With Intermittent Fasting.
Arbour MW, Stec M, Walker KC, Wika JC
Nurs Womens Health 2021 Apr;25(2):139-151. doi: 10.1016/j.nwh.2021.01.009. PMID: 33838849
Birth weight, early life weight gain and age at menarche: a systematic review of longitudinal studies.
Juul F, Chang VW, Brar P, Parekh N
Obes Rev 2017 Nov;18(11):1272-1288. Epub 2017 Sep 4 doi: 10.1111/obr.12587. PMID: 28872224
Endometriosis in teenagers.
Sarıdoğan E
Womens Health (Lond) 2015 Aug;11(5):705-9. Epub 2015 Aug 28 doi: 10.2217/whe.15.58. PMID: 26315257
Age at menarche and risk of asthma: systematic review and meta-analysis.
Lieberoth S, Gade EJ, Brok J, Backer V, Thomsen SF
J Asthma 2014 Aug;51(6):559-65. Epub 2014 Apr 7 doi: 10.3109/02770903.2014.903966. PMID: 24628525

Prognosis

Association Between Sex-Specific Risk Factors and Risk of New-Onset Atrial Fibrillation Among Women.
Lu Z, Aribas E, Geurts S, Roeters van Lennep JE, Ikram MA, Bos MM, de Groot NMS, Kavousi M
JAMA Netw Open 2022 Sep 1;5(9):e2229716. doi: 10.1001/jamanetworkopen.2022.29716. PMID: 36048441Free PMC Article
A Review of the Epidemiology of Breast Cancer in Asia: Focus on Risk Factors.
Youn HJ, Han W
Asian Pac J Cancer Prev 2020 Apr 1;21(4):867-880. doi: 10.31557/APJCP.2020.21.4.867. PMID: 32334446Free PMC Article
EMAS position statement: Predictors of premature and early natural menopause.
Mishra GD, Chung HF, Cano A, Chedraui P, Goulis DG, Lopes P, Mueck A, Rees M, Senturk LM, Simoncini T, Stevenson JC, Stute P, Tuomikoski P, Lambrinoudaki I
Maturitas 2019 May;123:82-88. Epub 2019 Mar 13 doi: 10.1016/j.maturitas.2019.03.008. PMID: 31027683
Early menarche, nulliparity and the risk for premature and early natural menopause.
Mishra GD, Pandeya N, Dobson AJ, Chung HF, Anderson D, Kuh D, Sandin S, Giles GG, Bruinsma F, Hayashi K, Lee JS, Mizunuma H, Cade JE, Burley V, Greenwood DC, Goodman A, Simonsen MK, Adami HO, Demakakos P, Weiderpass E
Hum Reprod 2017 Mar 1;32(3):679-686. doi: 10.1093/humrep/dew350. PMID: 28119483Free PMC Article
Diagnosis and Management of Endometrial Cancer.
Braun MM, Overbeek-Wager EA, Grumbo RJ
Am Fam Physician 2016 Mar 15;93(6):468-74. PMID: 26977831

Clinical prediction guides

EMAS position statement: Predictors of premature and early natural menopause.
Mishra GD, Chung HF, Cano A, Chedraui P, Goulis DG, Lopes P, Mueck A, Rees M, Senturk LM, Simoncini T, Stevenson JC, Stute P, Tuomikoski P, Lambrinoudaki I
Maturitas 2019 May;123:82-88. Epub 2019 Mar 13 doi: 10.1016/j.maturitas.2019.03.008. PMID: 31027683
Early menarche: A systematic review of its effect on sexual and reproductive health in low- and middle-income countries.
Ibitoye M, Choi C, Tai H, Lee G, Sommer M
PLoS One 2017;12(6):e0178884. Epub 2017 Jun 7 doi: 10.1371/journal.pone.0178884. PMID: 28591132Free PMC Article
Early menarche, nulliparity and the risk for premature and early natural menopause.
Mishra GD, Pandeya N, Dobson AJ, Chung HF, Anderson D, Kuh D, Sandin S, Giles GG, Bruinsma F, Hayashi K, Lee JS, Mizunuma H, Cade JE, Burley V, Greenwood DC, Goodman A, Simonsen MK, Adami HO, Demakakos P, Weiderpass E
Hum Reprod 2017 Mar 1;32(3):679-686. doi: 10.1093/humrep/dew350. PMID: 28119483Free PMC Article
Age at menarche and risks of all-cause and cardiovascular death: a systematic review and meta-analysis.
Charalampopoulos D, McLoughlin A, Elks CE, Ong KK
Am J Epidemiol 2014 Jul 1;180(1):29-40. Epub 2014 Jun 11 doi: 10.1093/aje/kwu113. PMID: 24920784Free PMC Article
Age at menarche and risk of asthma: systematic review and meta-analysis.
Lieberoth S, Gade EJ, Brok J, Backer V, Thomsen SF
J Asthma 2014 Aug;51(6):559-65. Epub 2014 Apr 7 doi: 10.3109/02770903.2014.903966. PMID: 24628525

Recent systematic reviews

Diet and Nutrients Intakes during Infancy and Childhood in Relation to Early Puberty: A Systematic Review and Meta-Analysis.
Tang J, Xue P, Huang X, Lin C, Liu S
Nutrients 2022 Nov 24;14(23) doi: 10.3390/nu14235004. PMID: 36501034Free PMC Article
Birth weight, early life weight gain and age at menarche: a systematic review of longitudinal studies.
Juul F, Chang VW, Brar P, Parekh N
Obes Rev 2017 Nov;18(11):1272-1288. Epub 2017 Sep 4 doi: 10.1111/obr.12587. PMID: 28872224
Early menarche: A systematic review of its effect on sexual and reproductive health in low- and middle-income countries.
Ibitoye M, Choi C, Tai H, Lee G, Sommer M
PLoS One 2017;12(6):e0178884. Epub 2017 Jun 7 doi: 10.1371/journal.pone.0178884. PMID: 28591132Free PMC Article
Systematic review and meta-analysis of age at menarche and risk of type 2 diabetes.
Janghorbani M, Mansourian M, Hosseini E
Acta Diabetol 2014 Aug;51(4):519-28. Epub 2014 Mar 27 doi: 10.1007/s00592-014-0579-x. PMID: 24671509
Age at menarche and risk of asthma: systematic review and meta-analysis.
Lieberoth S, Gade EJ, Brok J, Backer V, Thomsen SF
J Asthma 2014 Aug;51(6):559-65. Epub 2014 Apr 7 doi: 10.3109/02770903.2014.903966. PMID: 24628525

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