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Mammary duct ectasia

MedGen UID:
57538
Concept ID:
C0152442
Disease or Syndrome
Synonyms: Comedomastitis; Duct ectasia of breast; Ectasia of Mammary Duct; Ectasia of the Mammary Duct; Mammary Duct Ectasia
SNOMED CT: Mammary duct ectasia (22049009); Duct ectasia of breast (22049009); Comedomastitis (22049009)
 
HPO: HP:0020224

Definition

A non-proliferative inflammatory disorder of the large duct (milk duct) of the breast; as such, it affects nipple and areola complex. The condition is characterized by focal dilatation of the lactiferous duct system is due to endoluminal changes, as well as the loss of duct wall elastin, leading to abnormally dilated and tortuous lactiferous ducts with associated periductal inflammation and fibrosis. Mammary duct ectasia may present with nipple discharge or palpable mass. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMammary duct ectasia

Professional guidelines

PubMed

Wood JR
Radiol Technol 2021 Mar;92(4):383M-398M. PMID: 33653931
Ingvar C
Scand J Surg 2002;91(3):246-50. doi: 10.1177/145749690209100306. PMID: 12449466

Recent clinical studies

Etiology

Shi L, Wu J, Hu Y, Zhang X, Li Z, Xi PW, Wei JF, Ding Q
Nutrients 2022 Nov 14;14(22) doi: 10.3390/nu14224816. PMID: 36432503Free PMC Article
Tong Y, Hao Y, Gao X, Sun Y, Wang W
J Obstet Gynaecol Res 2020 Oct;46(10):2134-2141. Epub 2020 Jul 28 doi: 10.1111/jog.14380. PMID: 32725680
Pluguez-Turull CW, Nanyes JE, Quintero CJ, Alizai H, Mais DD, Kist KA, Dornbluth NC
Radiographics 2018 Mar-Apr;38(2):330-356. doi: 10.1148/rg.2018170095. PMID: 29528819
Bundred NJ, Dixon JM, Chetty U, Forrest AP
Br J Surg 1987 Jun;74(6):466-8. doi: 10.1002/bjs.1800740611. PMID: 3607398
Dixon JM, Anderson TJ, Lumsden AB, Elton RA, Roberts MM, Forrest AP
Br J Surg 1983 Oct;70(10):601-3. doi: 10.1002/bjs.1800701011. PMID: 6684964

Diagnosis

Shi L, Wu J, Hu Y, Zhang X, Li Z, Xi PW, Wei JF, Ding Q
Nutrients 2022 Nov 14;14(22) doi: 10.3390/nu14224816. PMID: 36432503Free PMC Article
Wood JR
Radiol Technol 2021 Mar;92(4):383M-398M. PMID: 33653931
Pluguez-Turull CW, Nanyes JE, Quintero CJ, Alizai H, Mais DD, Kist KA, Dornbluth NC
Radiographics 2018 Mar-Apr;38(2):330-356. doi: 10.1148/rg.2018170095. PMID: 29528819
McHoney M, Munro F, Mackinlay G
Early Hum Dev 2011 Aug;87(8):527-30. Epub 2011 May 7 doi: 10.1016/j.earlhumdev.2011.04.005. PMID: 21550735
Browning J, Bigrigg A, Taylor I
J R Soc Med 1986 Dec;79(12):715-6. doi: 10.1177/014107688607901210. PMID: 3806542Free PMC Article

Therapy

Tong Y, Hao Y, Gao X, Sun Y, Wang W
J Obstet Gynaecol Res 2020 Oct;46(10):2134-2141. Epub 2020 Jul 28 doi: 10.1111/jog.14380. PMID: 32725680
Abramson DJ
Ann Surg 1969 Feb;169(2):217-26. doi: 10.1097/00000658-196902000-00007. PMID: 5812659Free PMC Article

Prognosis

Laimon W, El-Hawary A, Aboelenin H, Elzohiri M, Abdelmaksoud S, Megahed N, Salem N
Eur J Pediatr 2021 Mar;180(3):977-982. Epub 2020 Sep 25 doi: 10.1007/s00431-020-03799-x. PMID: 32975593
Tong Y, Hao Y, Gao X, Sun Y, Wang W
J Obstet Gynaecol Res 2020 Oct;46(10):2134-2141. Epub 2020 Jul 28 doi: 10.1111/jog.14380. PMID: 32725680
Pluguez-Turull CW, Nanyes JE, Quintero CJ, Alizai H, Mais DD, Kist KA, Dornbluth NC
Radiographics 2018 Mar-Apr;38(2):330-356. doi: 10.1148/rg.2018170095. PMID: 29528819
Hartley MN, Stewart J, Benson EA
Br J Surg 1991 Oct;78(10):1187-8. doi: 10.1002/bjs.1800781013. PMID: 1958981
Browning J, Bigrigg A, Taylor I
J R Soc Med 1986 Dec;79(12):715-6. doi: 10.1177/014107688607901210. PMID: 3806542Free PMC Article

Clinical prediction guides

Shi L, Wu J, Hu Y, Zhang X, Li Z, Xi PW, Wei JF, Ding Q
Nutrients 2022 Nov 14;14(22) doi: 10.3390/nu14224816. PMID: 36432503Free PMC Article
Tong Y, Hao Y, Gao X, Sun Y, Wang W
J Obstet Gynaecol Res 2020 Oct;46(10):2134-2141. Epub 2020 Jul 28 doi: 10.1111/jog.14380. PMID: 32725680
Ballesio L, Maggi C, Savelli S, Angeletti M, Rabuffi P, Manganaro L, Porfiri LM
Radiol Med 2007 Apr;112(3):354-65. Epub 2007 Apr 20 doi: 10.1007/s11547-007-0146-4. PMID: 17440697
Vargas HI, Vargas MP, Eldrageely K, Gonzalez KD, Khalkhali I
Am Surg 2006 Feb;72(2):124-8. PMID: 16536240
Stringel G, Perelman A, Jimenez C
J Pediatr Surg 1986 Aug;21(8):671-4. doi: 10.1016/s0022-3468(86)80383-9. PMID: 3746598

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