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Malignant Palate Neoplasm

MedGen UID:: 57553
•Concept ID:: C0153378
•: Neoplastic Process

Synonyms:	CA - Cancer of palate; Cancer of palate; Cancer of Palate; Cancer of the Palate; Malignant Neoplasm of Palate; Malignant neoplasm of roof of mouth; Malignant Neoplasm of the Palate; Malignant Palate Tumor; Malignant tumor of palate; Malignant Tumor of Palate; Malignant tumor of roof of mouth; Malignant Tumor of the Palate; Palate Cancer
SNOMED CT:	Malignant tumor of roof of mouth (363390005); Malignant neoplasm of roof of mouth (363390005); Cancer of palate (363390005); CA - Cancer of palate (363390005); Malignant tumor of palate (363390005)

Definition

A primary or metastatic malignant neoplasm that affects the hard palate, soft palate, or uvula. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMalignant Palate Neoplasm

Disease
- Disorder by Site
  - Head and Neck Disorder
    - Head and neck neoplasm
      - Head and neck cancer
        Oral cavity cancer
        Malignant Palate Neoplasm
        Hard palate cancer
        Carcinoma of hard palate
        Hard Palate Adenoid Cystic Carcinoma
        Hard Palate Mucoepidermoid Carcinoma
        Hard Palate Squamous Cell Carcinoma
        Palate Carcinoma
        Carcinoma of soft palate
        Soft Palate Squamous Cell Carcinoma
        Palate Squamous Cell Carcinoma
        Palate Kaposi Sarcoma
        Soft palate cancer
        Uvula cancer

Professional guidelines

PubMed

Management of NK/T-Cell Lymphoma, Nasal Type.

Allen PB, Lechowicz MJ
J Oncol Pract 2019 Oct;15(10):513-520. doi: 10.1200/JOP.18.00719. PMID: 31600461 Free PMC Article

Oral cancer. The importance of early diagnosis and treatment.

Sciubba JJ
Am J Clin Dermatol 2001;2(4):239-51. doi: 10.2165/00128071-200102040-00005. PMID: 11705251

Diagnosis and management of primary nasal lymphoma of T-cell or NK-cell origin.

Liang R
Clin Lymphoma 2000 Jun;1(1):33-7; discussion 38. doi: 10.3816/clm.2000.n.002. PMID: 11707809

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Recent clinical studies

Etiology

PRAME Expression in Mucosal Melanoma of the Head and Neck Region.

Ricci C, Altavilla MV, Corti B, Pasquini E, Presutti L, Baietti AM, Amorosa L, Balbi T, Baldovini C, Ambrosi F, Grillini M, D'Errico A, Fiorentino M, Foschini MP
Am J Surg Pathol 2023 May 1;47(5):599-610. Epub 2023 Mar 13 doi: 10.1097/PAS.0000000000002032. PMID: 36912431 Free PMC Article

Prevalence and incidence of oral cancer in low- and middle-income countries: A scoping review.

Shrestha AD, Vedsted P, Kallestrup P, Neupane D
Eur J Cancer Care (Engl) 2020 Mar;29(2):e13207. Epub 2019 Dec 10 doi: 10.1111/ecc.13207. PMID: 31820851

Mucoepidermoid carcinoma of the head and neck in children.

Dombrowski ND, Wolter NE, Irace AL, Cunningham MJ, Mack JW, Marcus KJ, Vargas SO, Perez-Atayde AR, Robson CD, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 May;120:93-99. Epub 2019 Feb 10 doi: 10.1016/j.ijporl.2019.02.020. PMID: 30772619

Palate Lymphoma: CT Findings.

Celenk C, Celenk P
AJR Am J Roentgenol 2016 Sep;207(3):628-30. Epub 2016 Jun 24 doi: 10.2214/AJR.16.16360. PMID: 27341038

Neoplasms of the hard palate.

Aydil U, Kızıl Y, Bakkal FK, Köybaşıoğlu A, Uslu S
J Oral Maxillofac Surg 2014 Mar;72(3):619-26. Epub 2013 Oct 16 doi: 10.1016/j.joms.2013.08.019. PMID: 24139293

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Diagnosis

Palatal kissing tumors.

Bagnarosa T, Ferri J
J Stomatol Oral Maxillofac Surg 2023 Feb;124(1S):101306. Epub 2022 Oct 12 doi: 10.1016/j.jormas.2022.10.005. PMID: 36241159

The peculiar palatal mass.

Sandhu S, Sandhu PK, Sroussi HY
J Am Dent Assoc 2022 Dec;153(12):1184-1188. Epub 2021 Nov 24 doi: 10.1016/j.adaj.2021.07.031. PMID: 34836619

Pleomorphic adenoma of hard palate: a case report.

Yousra Z, Saliha C
Pan Afr Med J 2021;38:146. Epub 2021 Feb 9 doi: 10.11604/pamj.2021.38.146.26508. PMID: 33912316 Free PMC Article

Palate Lymphoma: CT Findings.

Celenk C, Celenk P
AJR Am J Roentgenol 2016 Sep;207(3):628-30. Epub 2016 Jun 24 doi: 10.2214/AJR.16.16360. PMID: 27341038

Abrikossoff's tumor.

Becelli R, Perugini M, Gasparini G, Cassoni A, Fabiani F
J Craniofac Surg 2001 Jan;12(1):78-81. doi: 10.1097/00001665-200101000-00013. PMID: 11314193

See all (1348)

Therapy

Skeletal and alveolar changes in conventional rapid palatal expansion (RPE) and miniscrew-assisted RPE (MARPE): a prospective randomized clinical trial using low-dose CBCT.

Chun JH, de Castro ACR, Oh S, Kim KH, Choi SH, Nojima LI, Nojima MDCG, Lee KJ
BMC Oral Health 2022 Apr 8;22(1):114. doi: 10.1186/s12903-022-02138-w. PMID: 35395801 Free PMC Article

Oncologic causes of oculopalatal tremors: neurophysiology and treatment.

Fiani B, Runnels J, Sarhadi K, Sarno E, Kondilis A
Acta Neurol Belg 2021 Oct;121(5):1111-1116. Epub 2021 Jul 20 doi: 10.1007/s13760-021-01761-8. PMID: 34286476

Oral Kaposi's sarcoma: a review and update.

Fatahzadeh M, Schwartz RA
Int J Dermatol 2013 Jun;52(6):666-72. doi: 10.1111/j.1365-4632.2012.05758.x. PMID: 23679875

Telomerase reverse transcriptase locus polymorphisms and cancer risk: a field synopsis and meta-analysis.

Mocellin S, Verdi D, Pooley KA, Landi MT, Egan KM, Baird DM, Prescott J, De Vivo I, Nitti D
J Natl Cancer Inst 2012 Jun 6;104(11):840-54. Epub 2012 Apr 20 doi: 10.1093/jnci/djs222. PMID: 22523397 Free PMC Article

Nasopharyngeal carcinoma.

Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883 Free PMC Article

See all (411)

Prognosis

Prevalence and incidence of oral cancer in low- and middle-income countries: A scoping review.

Shrestha AD, Vedsted P, Kallestrup P, Neupane D
Eur J Cancer Care (Engl) 2020 Mar;29(2):e13207. Epub 2019 Dec 10 doi: 10.1111/ecc.13207. PMID: 31820851

Polymorphous adenocarcinoma of salivary glands.

Mimica X, Katabi N, McGill MR, Hay A, Zanoni DK, Shah JP, Wong RJ, Cohen MA, Patel SG, Ganly I
Oral Oncol 2019 Aug;95:52-58. Epub 2019 Jun 7 doi: 10.1016/j.oraloncology.2019.06.002. PMID: 31345394 Free PMC Article

Oral malignant melanoma--an unusual presentation.

Thomas PS, Babu GS, Anusha RL, Shetty S
Gerodontology 2012 Jun;29(2):e1241-3. Epub 2010 Nov 17 doi: 10.1111/j.1741-2358.2010.00450.x. PMID: 22612841

Oral cavity and oropharynx tumors.

Stambuk HE, Karimi S, Lee N, Patel SG
Radiol Clin North Am 2007 Jan;45(1):1-20. doi: 10.1016/j.rcl.2006.10.010. PMID: 17157621

Salivary duct carcinoma.

Delgado R, Vuitch F, Albores-Saavedra J
Cancer 1993 Sep 1;72(5):1503-12. doi: 10.1002/1097-0142(19930901)72:5<1503::aid-cncr2820720503>3.0.co;2-k. PMID: 7688652

See all (947)

Clinical prediction guides

PRAME Expression in Mucosal Melanoma of the Head and Neck Region.

Skeletal and alveolar changes in conventional rapid palatal expansion (RPE) and miniscrew-assisted RPE (MARPE): a prospective randomized clinical trial using low-dose CBCT.

Chun JH, de Castro ACR, Oh S, Kim KH, Choi SH, Nojima LI, Nojima MDCG, Lee KJ
BMC Oral Health 2022 Apr 8;22(1):114. doi: 10.1186/s12903-022-02138-w. PMID: 35395801 Free PMC Article

Carcinoma Cuniculatum of the Oral Cavity: A Series of 6 Cases and Review of Literature.

Yadav S, Bal M, Rane S, Mittal N, Janu A, Patil A
Head Neck Pathol 2022 Mar;16(1):213-223. Epub 2021 Jun 2 doi: 10.1007/s12105-021-01340-6. PMID: 34076846 Free PMC Article

Sialolipomas of minor salivary glands: A multi-institutional study and literature review.

Cunha JLS, de Sousa SF, Mota CP, Rocha Silva JV, Cavalcante IL, Marinho EB, Soares CD, de Albuquerque-Júnior RLC, Cavalcante RB, Abrahão AC, Agostini M, Romañach MJ, de Andrade BAB, Vargas PA, de Almeida OP
J Oral Pathol Med 2021 Feb;50(2):210-219. Epub 2021 Jan 12 doi: 10.1111/jop.13124. PMID: 33187016

Hypertrophic Olivary Degeneration: Neurosurgical Perspective and Literature Review.

Onen MR, Moore K, Cikla U, Ucer M, Schmidt B, Field AS, Baskaya MK
World Neurosurg 2018 Apr;112:e763-e771. Epub 2018 Jan 31 doi: 10.1016/j.wneu.2018.01.150. PMID: 29382617

See all (436)

Recent systematic reviews

Long-term efficacy and stability of miniscrew-assisted rapid palatal expansion in mid to late adolescents and adults: a systematic review and meta-analysis.

Zeng W, Yan S, Yi Y, Chen H, Sun T, Zhang Y, Zhang J
BMC Oral Health 2023 Nov 3;23(1):829. doi: 10.1186/s12903-023-03574-y. PMID: 37924088 Free PMC Article

Local recurrence and survival after treatment of oral squamous cell carcinoma of the maxilla: A systematic review and meta-analysis.

Slieker FJB, Rombout DAA, de Bree R, Van Cann EM
Oral Surg Oral Med Oral Pathol Oral Radiol 2022 Jun;133(6):626-638. Epub 2021 Oct 13 doi: 10.1016/j.oooo.2021.10.003. PMID: 35165055

Oral Mucosal Melanoma.

Nisi M, Izzetti R, Gennai S, Pucci A, Lenzi C, Graziani F
J Craniofac Surg 2022 May 1;33(3):830-834. Epub 2021 Jul 30 doi: 10.1097/SCS.0000000000008054. PMID: 34334749

How Increased Nodal Metastasis and Recurrence in Cribriform Adenocarcinoma Relate to Polymorphous Adenocarcinoma and Survival: A Systematic Review.

Gates JC, Gargano SM, Cherkas E, Kraus DH, Tuluc M
J Oral Maxillofac Surg 2021 Sep;79(9):1970-1976. Epub 2021 Apr 20 doi: 10.1016/j.joms.2021.03.027. PMID: 34023291

Cervical metastases of oral maxillary squamous cell carcinoma: A systematic review and meta-analysis.

Zhang WB, Peng X
Head Neck 2016 Apr;38 Suppl 1:E2335-42. Epub 2016 Feb 18 doi: 10.1002/hed.24274. PMID: 26890607

See all (13)

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