U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Viral gastroenteritis caused by Rotavirus

MedGen UID:
575540
•Concept ID:
C0343363
•
Disease or Syndrome
Synonym: Rotaviral Enteritis
SNOMED CT: Viral gastroenteritis caused by Rotavirus (415822001)

Definition

Enteritis attributed to the rotavirus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVViral gastroenteritis caused by Rotavirus

Professional guidelines

PubMed

Rotavirus infection in children in Southeast Asia 2008-2018: disease burden, genotype distribution, seasonality, and vaccination.
Lestari FB, Vongpunsawad S, Wanlapakorn N, Poovorawan Y
J Biomed Sci 2020 May 21;27(1):66. doi: 10.1186/s12929-020-00649-8. PMID: 32438911Free PMC Article
Cost-effective options for the prevention and management of gastrointestinal and liver disease in the Asia-Pacific region.
Roberts-Thomson IC, Lung T
J Gastroenterol Hepatol 2018 Jan;33(1):121-127. doi: 10.1111/jgh.13925. PMID: 28833619
Group A rotavirus universal mass vaccination: how and to what extent will selective pressure influence prevalence of rotavirus genotypes?
Matthijnssens J, Nakagomi O, Kirkwood CD, Ciarlet M, Desselberger U, Van Ranst M
Expert Rev Vaccines 2012 Nov;11(11):1347-54. doi: 10.1586/erv.12.105. PMID: 23249234

Recent clinical studies

Etiology

Cost-of-illness of gastroenteritis caused by rotavirus in Chinese children less than 5 years.
Fu XL, Ma Y, Li Z, Qi YY, Wang SJ, Fu LJ, Wang SM, von Seidlein L, Wang XY
Hum Vaccin Immunother 2023 Dec 15;19(3):2276619. Epub 2023 Nov 27 doi: 10.1080/21645515.2023.2276619. PMID: 38013426Free PMC Article
Burden of Rotavirus Diarrhea in Under five Indian Children.
Kumar A, Basu S, Vashishtha V, Choudhury P
Indian Pediatr 2016 Jul 8;53(7):607-17. doi: 10.1007/s13312-016-0896-y. PMID: 27508538
Rotavirus vaccines: viral shedding and risk of transmission.
Anderson EJ
Lancet Infect Dis 2008 Oct;8(10):642-9. doi: 10.1016/S1473-3099(08)70231-7. PMID: 18922486
Rotavirus infection in adults.
Anderson EJ, Weber SG
Lancet Infect Dis 2004 Feb;4(2):91-9. doi: 10.1016/S1473-3099(04)00928-4. PMID: 14871633Free PMC Article
Gastroenteritis viruses: an overview.
Glass RI, Bresee J, Jiang B, Gentsch J, Ando T, Fankhauser R, Noel J, Parashar U, Rosen B, Monroe SS
Novartis Found Symp 2001;238:5-19; discussion 19-25. doi: 10.1002/0470846534.ch2. PMID: 11444035

Diagnosis

Rotavirus infection in adults.
Anderson EJ, Weber SG
Lancet Infect Dis 2004 Feb;4(2):91-9. doi: 10.1016/S1473-3099(04)00928-4. PMID: 14871633Free PMC Article
Infection and the gut.
Blakelock RT, Beasley SW
Semin Pediatr Surg 2003 Nov;12(4):265-74. doi: 10.1053/j.sempedsurg.2003.08.008. PMID: 14655166
Gastroenteritis viruses: an overview.
Glass RI, Bresee J, Jiang B, Gentsch J, Ando T, Fankhauser R, Noel J, Parashar U, Rosen B, Monroe SS
Novartis Found Symp 2001;238:5-19; discussion 19-25. doi: 10.1002/0470846534.ch2. PMID: 11444035
Infantile convulsions with mild gastroenteritis.
Abe T, Kobayashi M, Araki K, Kodama H, Fujita Y, Shinozaki T, Ushijima H
Brain Dev 2000 Aug;22(5):301-6. doi: 10.1016/s0387-7604(00)00111-x. PMID: 10891637
Enteric adenoviruses.
Wadell G, Allard A, Johansson M, Svensson L, Uhnoo I
Ciba Found Symp 1987;128:63-91. doi: 10.1002/9780470513460.ch5. PMID: 3036447

Therapy

Cost-of-illness of gastroenteritis caused by rotavirus in Chinese children less than 5 years.
Fu XL, Ma Y, Li Z, Qi YY, Wang SJ, Fu LJ, Wang SM, von Seidlein L, Wang XY
Hum Vaccin Immunother 2023 Dec 15;19(3):2276619. Epub 2023 Nov 27 doi: 10.1080/21645515.2023.2276619. PMID: 38013426Free PMC Article
A tale of antiviral counterattacks in rotavirus infection.
Bhuinya A, Dass D, Banerjee A, Mukherjee A
Microbiol Res 2022 Jul;260:127046. Epub 2022 Apr 22 doi: 10.1016/j.micres.2022.127046. PMID: 35487138
Genipin inhibits rotavirus-induced diarrhea by suppressing viral replication and regulating inflammatory responses.
Kim JH, Kim K, Kim W
Sci Rep 2020 Sep 28;10(1):15836. doi: 10.1038/s41598-020-72968-7. PMID: 32985574Free PMC Article
Rotavirus vaccines: viral shedding and risk of transmission.
Anderson EJ
Lancet Infect Dis 2008 Oct;8(10):642-9. doi: 10.1016/S1473-3099(08)70231-7. PMID: 18922486
Infection and the gut.
Blakelock RT, Beasley SW
Semin Pediatr Surg 2003 Nov;12(4):265-74. doi: 10.1053/j.sempedsurg.2003.08.008. PMID: 14655166

Prognosis

Burden of Rotavirus Diarrhea in Under five Indian Children.
Kumar A, Basu S, Vashishtha V, Choudhury P
Indian Pediatr 2016 Jul 8;53(7):607-17. doi: 10.1007/s13312-016-0896-y. PMID: 27508538
Impact of rotavirus vaccine introduction on rotavirus-associated seizures and a related possible mechanism.
Yeom JS, Kim YS, Kim RB, Park JS, Seo JH, Park E, Lim JY, Park CH, Woo HO, Youn HS
J Child Neurol 2015 May;30(6):729-34. Epub 2014 Aug 12 doi: 10.1177/0883073814542944. PMID: 25117417
Rotavirus vaccine for preventing diarrhoea.
Soares-Weiser K, Goldberg E, Tamimi G, Pitan OC, Leibovici L
Cochrane Database Syst Rev 2004;2004(1):CD002848. doi: 10.1002/14651858.CD002848.pub2. PMID: 14973994Free PMC Article
Rotavirus infection in adults.
Anderson EJ, Weber SG
Lancet Infect Dis 2004 Feb;4(2):91-9. doi: 10.1016/S1473-3099(04)00928-4. PMID: 14871633Free PMC Article
Global illness and deaths caused by rotavirus disease in children.
Parashar UD, Hummelman EG, Bresee JS, Miller MA, Glass RI
Emerg Infect Dis 2003 May;9(5):565-72. doi: 10.3201/eid0905.020562. PMID: 12737740Free PMC Article

Clinical prediction guides

Clinical manifestations associated with acute viral gastroenteritis pathogens among pediatric patients in Qatar.
Abdel-Rahman ME, Mathew S, Al Thani AA, Ansari KA, Yassine HM
J Med Virol 2021 Aug;93(8):4794-4804. Epub 2021 Feb 19 doi: 10.1002/jmv.26859. PMID: 33559912
Mixed Viral-Bacterial Infections and Their Effects on Gut Microbiota and Clinical Illnesses in Children.
Mathew S, Smatti MK, Al Ansari K, Nasrallah GK, Al Thani AA, Yassine HM
Sci Rep 2019 Jan 29;9(1):865. doi: 10.1038/s41598-018-37162-w. PMID: 30696865Free PMC Article
Impact of rotavirus vaccine on all-cause diarrhea and rotavirus hospitalizations in Madagascar.
Rahajamanana VL, Raboba JL, Rakotozanany A, Razafindraibe NJ, Andriatahirintsoa EJPR, Razafindrakoto AC, Mioramalala SA, Razaiarimanga C, Weldegebriel GG, Burnett E, Mwenda JM, Seheri M, Mphahlele MJ, Robinson AL
Vaccine 2018 Nov 12;36(47):7198-7204. Epub 2017 Sep 25 doi: 10.1016/j.vaccine.2017.08.091. PMID: 28958809Free PMC Article
Clinical and epidemiological characteristics of norovirus gastroenteritis among hospitalized children in Lebanon.
Melhem NM, Zaraket H, Kreidieh K, Ali Z, Hammadi M, Ghanem S, Hajar F, Haidar A, Inati A, Rajab M, Fakhouri H, Ghanem B, Baasiri G, Dbaibo G
World J Gastroenterol 2016 Dec 28;22(48):10557-10565. doi: 10.3748/wjg.v22.i48.10557. PMID: 28082807Free PMC Article
Group A rotavirus universal mass vaccination: how and to what extent will selective pressure influence prevalence of rotavirus genotypes?
Matthijnssens J, Nakagomi O, Kirkwood CD, Ciarlet M, Desselberger U, Van Ranst M
Expert Rev Vaccines 2012 Nov;11(11):1347-54. doi: 10.1586/erv.12.105. PMID: 23249234

Recent systematic reviews

Rotavirus outbreaks in China, 1982-2021: a systematic review.
Tian Y, Yu F, Zhang G, Tian C, Wang X, Chen Y, Yan H, Jia L, Zhang D, Wang Q, Gao Z
Front Public Health 2024;12:1423573. Epub 2024 Aug 8 doi: 10.3389/fpubh.2024.1423573. PMID: 39175894Free PMC Article
Do Rotavirus Strains Affect Vaccine Effectiveness? A Systematic Review and Meta-analysis.
Cates JE, Amin AB, Tate JE, Lopman B, Parashar U
Pediatr Infect Dis J 2021 Dec 1;40(12):1135-1143. doi: 10.1097/INF.0000000000003286. PMID: 34870393Free PMC Article
Systematic review with meta-analyses: does the pathogen matter in post-infectious irritable bowel syndrome?
Svendsen AT, Bytzer P, Engsbro AL
Scand J Gastroenterol 2019 May;54(5):546-562. Epub 2019 May 21 doi: 10.1080/00365521.2019.1607897. PMID: 31112663
Update on the disease burden and circulating strains of rotavirus in China: a systematic review and meta-analysis.
Liu N, Xu Z, Li D, Zhang Q, Wang H, Duan ZJ
Vaccine 2014 Jul 31;32(35):4369-4375. Epub 2014 Jun 20 doi: 10.1016/j.vaccine.2014.06.018. PMID: 24958704
Rotavirus vaccine for preventing diarrhoea.
Soares-Weiser K, Goldberg E, Tamimi G, Pitan OC, Leibovici L
Cochrane Database Syst Rev 2004;2004(1):CD002848. doi: 10.1002/14651858.CD002848.pub2. PMID: 14973994Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...