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Subglottis cancer

MedGen UID:
57562
•Concept ID:
C0153485
•
Neoplastic Process
Synonyms: Ca larynx - subglottis; cancer of subglottis; Malignant Neoplasm of Subglottis; malignant neoplasm of subglottis; Malignant Neoplasm of the Subglottis; malignant neoplasm of the subglottis; Malignant Subglottic Neoplasm; malignant subglottic neoplasm; Malignant Subglottic Tumor; malignant subglottic tumor; malignant subglottic tumour; Malignant Subglottis Neoplasm; malignant subglottis neoplasm; Malignant Subglottis Tumor; malignant subglottis tumor; malignant subglottis tumour; Malignant tumor of subglottis; Malignant Tumor of Subglottis; malignant tumor of subglottis; Malignant Tumor of the Subglottis; malignant tumor of the subglottis; malignant tumour of subglottis; malignant tumour of the subglottis; subglottis cancer
SNOMED CT: Ca larynx - subglottis (363430007); Malignant tumor of subglottis (363430007)
 
Monarch Initiative: MONDO:0001293

Definition

A malignant neoplasm that affects the subglottic area of the larynx. The vast majority of cases are squamous cell carcinomas. [from NCI]

Professional guidelines

PubMed

Strategies and Controversies in the Treatment With Carbon Dioxide Laser of Laryngeal Hemangioma: A Case Series and Review of the Literature.
Mesolella M, Allosso S, Mansueto G, Fuggi M, Motta G
Ear Nose Throat J 2022 Jun;101(5):326-331. Epub 2020 Sep 13 doi: 10.1177/0145561320952191. PMID: 32921178
Updated National Comprehensive Cancer Network guidelines for treatment of head and neck cancers 2010-2017.
Wierzbicka M, Napierała J
Otolaryngol Pol 2017 Dec 30;71(6):1-6. doi: 10.5604/01.3001.0010.7193. PMID: 29327681
The pathology and management of subglottic cancer.
Ferlito A, Rinaldo A
Eur Arch Otorhinolaryngol 2000;257(3):168-73. doi: 10.1007/s004050050217. PMID: 10839493

Recent clinical studies

Etiology

Advances in Organ Preservation for Laryngeal Cancer.
Campbell G, Glazer TA, Kimple RJ, Bruce JY
Curr Treat Options Oncol 2022 Apr;23(4):594-608. Epub 2022 Mar 18 doi: 10.1007/s11864-022-00945-5. PMID: 35303749Free PMC Article
Thyroid gland invasion in total laryngectomy and total laryngopharyngectomy: a systematic review and meta-analysis of the English literature.
Kumar R, Drinnan M, Robinson M, Meikle D, Stafford F, Welch A, Zammit-Maempel I, Paleri V
Clin Otolaryngol 2013 Oct;38(5):372-8. doi: 10.1111/coa.12165. PMID: 23998197
Alcohol and laryngeal cancer: an update.
La Vecchia C, Zhang ZF, Altieri A
Eur J Cancer Prev 2008 Apr;17(2):116-24. doi: 10.1097/CEJ.0b013e3282b6fd40. PMID: 18287868
Alcohol consumption and risk of laryngeal cancer.
Altieri A, Garavello W, Bosetti C, Gallus S, La Vecchia C
Oral Oncol 2005 Nov;41(10):956-65. Epub 2005 May 31 doi: 10.1016/j.oraloncology.2005.02.004. PMID: 15927525
Endoscopic vertical partial laryngectomy.
Davis RK, Hadley K, Smith ME
Laryngoscope 2004 Feb;114(2):236-40. doi: 10.1097/00005537-200402000-00012. PMID: 14755197

Diagnosis

Prognosis of subglottic carcinoma: Is it really worse?
Coskun H, Mendenhall WM, Rinaldo A, Rodrigo JP, Suárez C, Strojan P, López F, Mondin V, Saba NF, Shaha AR, Smee R, Takes RP, Ferlito A
Head Neck 2019 Feb;41(2):511-521. Epub 2018 Jun 26 doi: 10.1002/hed.25172. PMID: 29947111
Updated National Comprehensive Cancer Network guidelines for treatment of head and neck cancers 2010-2017.
Wierzbicka M, Napierała J
Otolaryngol Pol 2017 Dec 30;71(6):1-6. doi: 10.5604/01.3001.0010.7193. PMID: 29327681
Laryngeal schwannoma: a systematic review.
Wong BLK, Bathala S, Grant D
Eur Arch Otorhinolaryngol 2017 Jan;274(1):25-34. Epub 2016 Mar 28 doi: 10.1007/s00405-016-4013-6. PMID: 27020268
Radiologic evaluation of larynx cancer.
Blitz AM, Aygun N
Otolaryngol Clin North Am 2008 Aug;41(4):697-713, vi. doi: 10.1016/j.otc.2008.01.015. PMID: 18570954
The pathology and management of subglottic cancer.
Ferlito A, Rinaldo A
Eur Arch Otorhinolaryngol 2000;257(3):168-73. doi: 10.1007/s004050050217. PMID: 10839493

Therapy

Paratracheal lymph node dissection during total (pharyngo-)laryngectomy: A systematic review and meta-analysis.
Chabrillac E, Jackson R, Mattei P, D'Andréa G, Vergez S, Dupret-Bories A, Edafe O
Oral Oncol 2022 Sep;132:106017. Epub 2022 Jul 10 doi: 10.1016/j.oraloncology.2022.106017. PMID: 35830760
Advances in Organ Preservation for Laryngeal Cancer.
Campbell G, Glazer TA, Kimple RJ, Bruce JY
Curr Treat Options Oncol 2022 Apr;23(4):594-608. Epub 2022 Mar 18 doi: 10.1007/s11864-022-00945-5. PMID: 35303749Free PMC Article
Alcohol and laryngeal cancer: an update.
La Vecchia C, Zhang ZF, Altieri A
Eur J Cancer Prev 2008 Apr;17(2):116-24. doi: 10.1097/CEJ.0b013e3282b6fd40. PMID: 18287868
Alcohol consumption and risk of laryngeal cancer.
Altieri A, Garavello W, Bosetti C, Gallus S, La Vecchia C
Oral Oncol 2005 Nov;41(10):956-65. Epub 2005 May 31 doi: 10.1016/j.oraloncology.2005.02.004. PMID: 15927525
Management of acute and chronic disorders of the trachea and subglottis.
Brooks R, Bartlett RH, Gazzaniga AB
Am J Surg 1985 Jul;150(1):24-31. doi: 10.1016/0002-9610(85)90005-4. PMID: 3893182

Prognosis

Prognosis of subglottic carcinoma: Is it really worse?
Coskun H, Mendenhall WM, Rinaldo A, Rodrigo JP, Suárez C, Strojan P, López F, Mondin V, Saba NF, Shaha AR, Smee R, Takes RP, Ferlito A
Head Neck 2019 Feb;41(2):511-521. Epub 2018 Jun 26 doi: 10.1002/hed.25172. PMID: 29947111
Laryngeal schwannoma: a systematic review.
Wong BLK, Bathala S, Grant D
Eur Arch Otorhinolaryngol 2017 Jan;274(1):25-34. Epub 2016 Mar 28 doi: 10.1007/s00405-016-4013-6. PMID: 27020268
Radiologic evaluation of larynx cancer.
Blitz AM, Aygun N
Otolaryngol Clin North Am 2008 Aug;41(4):697-713, vi. doi: 10.1016/j.otc.2008.01.015. PMID: 18570954
The pathology and management of subglottic cancer.
Ferlito A, Rinaldo A
Eur Arch Otorhinolaryngol 2000;257(3):168-73. doi: 10.1007/s004050050217. PMID: 10839493
Peristomal recurrence.
Hosal IN, Onerci M, Turan E
Am J Otolaryngol 1993 May-Jun;14(3):206-8. doi: 10.1016/0196-0709(93)90031-2. PMID: 8338204

Clinical prediction guides

Concordance between head and neck MRI and histopathology in detecting laryngeal subsite invasion among patients with laryngeal cancer.
Mohamad I, Hejleh TA, Qandeel M, Al-Hussaini M, Koro S, Taqash A, Almousa A, Abuhijla F, Abuhijlih R, Ajlouni F, Al-Ibraheem A, Laban DA, Hussein T, Mayta E, Al-Gargaz W, Hosni A
Cancer Imaging 2023 Oct 19;23(1):99. doi: 10.1186/s40644-023-00618-y. PMID: 37858162Free PMC Article
Epidemiological Study of Laryngeal Carcinoma in Western Nepal.
Koirala K
Asian Pac J Cancer Prev 2015;16(15):6541-4. doi: 10.7314/apjcp.2015.16.15.6541. PMID: 26434871
Subglottic extramedullary plasmacytoma with light chain multiple myeloma masquerading as adult-onset asthma.
Gan YJ, Chopra A, Kanagalingam J
J Voice 2014 May;28(3):394.e1-4. Epub 2014 Feb 1 doi: 10.1016/j.jvoice.2013.10.016. PMID: 24491498
Thyroid gland invasion in total laryngectomy and total laryngopharyngectomy: a systematic review and meta-analysis of the English literature.
Kumar R, Drinnan M, Robinson M, Meikle D, Stafford F, Welch A, Zammit-Maempel I, Paleri V
Clin Otolaryngol 2013 Oct;38(5):372-8. doi: 10.1111/coa.12165. PMID: 23998197
Efficacy and toxicity of (chemo)radiotherapy for primary subglottic cancer.
Hata M, Taguchi T, Koike I, Nishimura G, Takahashi M, Komatsu M, Sano D, Odagiri K, Minagawa Y, Inoue T
Strahlenther Onkol 2013 Jan;189(1):26-32. Epub 2012 Nov 18 doi: 10.1007/s00066-012-0178-0. PMID: 23161117

Recent systematic reviews

Paratracheal lymph node dissection during total (pharyngo-)laryngectomy: A systematic review and meta-analysis.
Chabrillac E, Jackson R, Mattei P, D'Andréa G, Vergez S, Dupret-Bories A, Edafe O
Oral Oncol 2022 Sep;132:106017. Epub 2022 Jul 10 doi: 10.1016/j.oraloncology.2022.106017. PMID: 35830760
Epidemiological, clinical and oncological outcomes of young patients with laryngeal cancer: a systematic review.
Lechien JR, Maniaci A, Hans S, Iannella G, Fakhry N, Mayo-Yáñez M, Ayad T, Mannelli G, Chiesa-Estomba CM
Eur Arch Otorhinolaryngol 2022 Dec;279(12):5741-5753. Epub 2022 Jun 2 doi: 10.1007/s00405-022-07466-9. PMID: 35652941
Laryngeal schwannoma: a systematic review.
Wong BLK, Bathala S, Grant D
Eur Arch Otorhinolaryngol 2017 Jan;274(1):25-34. Epub 2016 Mar 28 doi: 10.1007/s00405-016-4013-6. PMID: 27020268
Laryngeal Adenoid Cystic Carcinoma: A Systematic Review.
Marchiano E, Chin OY, Fang CH, Park RC, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2016 Mar;154(3):433-9. Epub 2015 Dec 23 doi: 10.1177/0194599815621884. PMID: 26701176
Thyroid gland invasion in total laryngectomy and total laryngopharyngectomy: a systematic review and meta-analysis of the English literature.
Kumar R, Drinnan M, Robinson M, Meikle D, Stafford F, Welch A, Zammit-Maempel I, Paleri V
Clin Otolaryngol 2013 Oct;38(5):372-8. doi: 10.1111/coa.12165. PMID: 23998197

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