U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Benign neoplasm of choroid

MedGen UID:
57581
•Concept ID:
C0154028
•
Neoplastic Process
Synonyms: Benign Choroid Neoplasm; benign choroid neoplasm; Benign Choroid Tumor; benign choroid tumor; benign choroid tumour; Benign Neoplasm of Choroid; benign neoplasm of choroid; Benign Neoplasm of the Choroid; benign neoplasm of the choroid; Benign tumor of choroid; Benign Tumor of Choroid; benign tumor of choroid; Benign Tumor of the Choroid; benign tumor of the choroid; benign tumour of choroid; benign tumour of the choroid; optic choroid benign neoplasm
SNOMED CT: Benign neoplasm of choroid (92059004); Benign tumor of choroid (92059004)
 
Monarch Initiative: MONDO:0021487

Definition

A neoplasm that arises from the choroid and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of choroid

Professional guidelines

PubMed

5-aminolevulinic acid photodynamic therapy for the treatment of high-grade gliomas.
Mahmoudi K, Garvey KL, Bouras A, Cramer G, Stepp H, Jesu Raj JG, Bozec D, Busch TM, Hadjipanayis CG
J Neurooncol 2019 Feb;141(3):595-607. Epub 2019 Jan 18 doi: 10.1007/s11060-019-03103-4. PMID: 30659522Free PMC Article
Metastatic disease from uveal melanoma: treatment options and future prospects.
Carvajal RD, Schwartz GK, Tezel T, Marr B, Francis JH, Nathan PD
Br J Ophthalmol 2017 Jan;101(1):38-44. Epub 2016 Aug 29 doi: 10.1136/bjophthalmol-2016-309034. PMID: 27574175Free PMC Article
Uveal melanoma: From diagnosis to treatment and the science in between.
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article

Recent clinical studies

Etiology

Tamoxifen related chorioretinal structural changes.
Erbahçeci Timur İE, Açıkgöz V, Uğurlu N, Yalçın B, Şendur MAN, Hızal M, Kara H
Cutan Ocul Toxicol 2023 Sep;42(3):109-117. Epub 2023 Jun 15 doi: 10.1080/15569527.2023.2220388. PMID: 37272809
Spectral-domain optical coherence tomography biomarkers in vitreoretinal lymphoma.
Guan W, Xiao Y, Zhao H, Hu F, Chen C, Peng X
Clin Exp Ophthalmol 2023 Mar;51(2):144-153. Epub 2023 Jan 4 doi: 10.1111/ceo.14197. PMID: 36567492
Updates in imaging in ocular oncology.
Davila JR, Mruthyunjaya P
F1000Res 2019;8 Epub 2019 Oct 1 doi: 10.12688/f1000research.19979.1. PMID: 31602297Free PMC Article
An Update on Oculodermal Melanocytosis and Rare Associated Conditions.
Plateroti AM, Scavella V, Abdolrahimzadeh B, Plateroti R, Rahimi S
Semin Ophthalmol 2017;32(4):524-528. Epub 2016 Apr 15 doi: 10.3109/08820538.2015.1118133. PMID: 27083007
Choroidal melanoma and pregnancy.
Lemaître S, Lévy-Gabriel C, Desjardins L, Plancher C, Asselain B, Vincent-Salomon A, Lumbroso-Le Rouic L, Dendale R, Rouzier R, Delacroix S, Cassoux N
Acta Ophthalmol 2016 Nov;94(7):e652-e660. Epub 2016 Mar 24 doi: 10.1111/aos.12984. PMID: 27009598

Diagnosis

Posterior segment manifestations of ocular metastasis.
Kongwattananon W, Pothikamjorn T, Somkijrungroj T
Curr Opin Ophthalmol 2023 Nov 1;34(6):522-528. Epub 2023 Aug 9 doi: 10.1097/ICU.0000000000000988. PMID: 37556166
Clinical features and therapeutic management of choroidal osteoma: A systematic review.
Zhang L, Ran QB, Lei CY, Zhang MX
Surv Ophthalmol 2023 Nov-Dec;68(6):1084-1092. Epub 2023 Jun 14 doi: 10.1016/j.survophthal.2023.06.002. PMID: 37321477
New concepts in the diagnosis and management of choroidal metastases.
Mathis T, Jardel P, Loria O, Delaunay B, Nguyen AM, Lanza F, Mosci C, Caujolle JP, Kodjikian L, Thariat J
Prog Retin Eye Res 2019 Jan;68:144-176. Epub 2018 Sep 19 doi: 10.1016/j.preteyeres.2018.09.003. PMID: 30240895
Choroidal hemangioma.
Singh AD, Kaiser PK, Sears JE
Ophthalmol Clin North Am 2005 Mar;18(1):151-61, ix. doi: 10.1016/j.ohc.2004.07.004. PMID: 15763200
Choroidal osteoma.
Kadrmas EF, Weiter JJ
Int Ophthalmol Clin 1997 Fall;37(4):171-82. doi: 10.1097/00004397-199703740-00015. PMID: 9429940

Therapy

Tamoxifen related chorioretinal structural changes.
Erbahçeci Timur İE, Açıkgöz V, Uğurlu N, Yalçın B, Şendur MAN, Hızal M, Kara H
Cutan Ocul Toxicol 2023 Sep;42(3):109-117. Epub 2023 Jun 15 doi: 10.1080/15569527.2023.2220388. PMID: 37272809
Photodynamic therapy for choroidal melanoma: What is the response rate?
Yordi S, Soto H, Bowen RC, Singh AD
Surv Ophthalmol 2021 Jul-Aug;66(4):552-559. Epub 2021 Jan 2 doi: 10.1016/j.survophthal.2020.09.006. PMID: 33400941
5-aminolevulinic acid photodynamic therapy for the treatment of high-grade gliomas.
Mahmoudi K, Garvey KL, Bouras A, Cramer G, Stepp H, Jesu Raj JG, Bozec D, Busch TM, Hadjipanayis CG
J Neurooncol 2019 Feb;141(3):595-607. Epub 2019 Jan 18 doi: 10.1007/s11060-019-03103-4. PMID: 30659522Free PMC Article
Neurofibromatosis Type 1: Review and Update on Emerging Therapies.
Karaconji T, Whist E, Jamieson RV, Flaherty MP, Grigg JRB
Asia Pac J Ophthalmol (Phila) 2019 Jan-Feb;8(1):62-72. Epub 2018 Nov 2 doi: 10.22608/APO.2018182. PMID: 30387339
New concepts in the diagnosis and management of choroidal metastases.
Mathis T, Jardel P, Loria O, Delaunay B, Nguyen AM, Lanza F, Mosci C, Caujolle JP, Kodjikian L, Thariat J
Prog Retin Eye Res 2019 Jan;68:144-176. Epub 2018 Sep 19 doi: 10.1016/j.preteyeres.2018.09.003. PMID: 30240895

Prognosis

Metastasis of the choroid plexuses: A systematic review of the literature and case illustration.
Garrido E, Alqahtani K, Lozouet M, Derrey S, Gilard V
Neurochirurgie 2023 Mar;69(2):101412. Epub 2023 Jan 14 doi: 10.1016/j.neuchi.2023.101412. PMID: 36649887
Secondary ocular malignancies: A review.
Yeung AM, Wells JR, Grossniklaus HE
Clin Exp Ophthalmol 2021 Mar;49(2):161-168. Epub 2021 Jan 10 doi: 10.1111/ceo.13889. PMID: 33426794
Photodynamic therapy for choroidal melanoma: What is the response rate?
Yordi S, Soto H, Bowen RC, Singh AD
Surv Ophthalmol 2021 Jul-Aug;66(4):552-559. Epub 2021 Jan 2 doi: 10.1016/j.survophthal.2020.09.006. PMID: 33400941
Predictors of recurrence in the management of chordoid meningioma.
Choy W, Ampie L, Lamano JB, Kesavabhotla K, Mao Q, Parsa AT, Bloch O
J Neurooncol 2016 Jan;126(1):107-116. Epub 2015 Sep 26 doi: 10.1007/s11060-015-1940-9. PMID: 26409888Free PMC Article
Choroidal hemangioma.
Singh AD, Kaiser PK, Sears JE
Ophthalmol Clin North Am 2005 Mar;18(1):151-61, ix. doi: 10.1016/j.ohc.2004.07.004. PMID: 15763200

Clinical prediction guides

Spectral-domain optical coherence tomography biomarkers in vitreoretinal lymphoma.
Guan W, Xiao Y, Zhao H, Hu F, Chen C, Peng X
Clin Exp Ophthalmol 2023 Mar;51(2):144-153. Epub 2023 Jan 4 doi: 10.1111/ceo.14197. PMID: 36567492
Photodynamic therapy for choroidal melanoma: What is the response rate?
Yordi S, Soto H, Bowen RC, Singh AD
Surv Ophthalmol 2021 Jul-Aug;66(4):552-559. Epub 2021 Jan 2 doi: 10.1016/j.survophthal.2020.09.006. PMID: 33400941
Predictors of recurrence in the management of chordoid meningioma.
Choy W, Ampie L, Lamano JB, Kesavabhotla K, Mao Q, Parsa AT, Bloch O
J Neurooncol 2016 Jan;126(1):107-116. Epub 2015 Sep 26 doi: 10.1007/s11060-015-1940-9. PMID: 26409888Free PMC Article
Uveal Melanoma UK National Guidelines.
Nathan P, Cohen V, Coupland S, Curtis K, Damato B, Evans J, Fenwick S, Kirkpatrick L, Li O, Marshall E, McGuirk K, Ottensmeier C, Pearce N, Salvi S, Stedman B, Szlosarek P, Turnbull N; United Kingdom Uveal Melanoma Guideline Development Working Group
Eur J Cancer 2015 Nov;51(16):2404-12. Epub 2015 Aug 13 doi: 10.1016/j.ejca.2015.07.013. PMID: 26278648
Circumscribed choroidal hemangioma.
Mashayekhi A, Shields CL
Curr Opin Ophthalmol 2003 Jun;14(3):142-9. doi: 10.1097/00055735-200306000-00006. PMID: 12777933

Recent systematic reviews

Clinical features and therapeutic management of choroidal osteoma: A systematic review.
Zhang L, Ran QB, Lei CY, Zhang MX
Surv Ophthalmol 2023 Nov-Dec;68(6):1084-1092. Epub 2023 Jun 14 doi: 10.1016/j.survophthal.2023.06.002. PMID: 37321477
Pathophysiology, diagnosis, and management of glaucoma associated with Sturge-Weber syndrome.
Javaid U, Ali MH, Jamal S, Butt NH
Int Ophthalmol 2018 Feb;38(1):409-416. Epub 2017 Jan 7 doi: 10.1007/s10792-016-0412-3. PMID: 28064423
Predictors of recurrence in the management of chordoid meningioma.
Choy W, Ampie L, Lamano JB, Kesavabhotla K, Mao Q, Parsa AT, Bloch O
J Neurooncol 2016 Jan;126(1):107-116. Epub 2015 Sep 26 doi: 10.1007/s11060-015-1940-9. PMID: 26409888Free PMC Article
Management of choroidal metastases.
Jardel P, Sauerwein W, Olivier T, Bensoussan E, Maschi C, Lanza F, Mosci C, Gastaud L, Angellier G, Marcy PY, Herault J, Caujolle JP, Dendale R, Thariat J
Cancer Treat Rev 2014 Dec;40(10):1119-28. Epub 2014 Oct 5 doi: 10.1016/j.ctrv.2014.09.006. PMID: 25451606
Breast cancer (metastatic).
Stebbing J, Ngan S
BMJ Clin Evid 2010 Sep 8;2010 PMID: 21418674Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...