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Congenital candidiasis

MedGen UID:
575892
•Concept ID:
C0343875
•
Disease or Syndrome
Synonyms: Congenital Candidiasis; congenital candidiasis; Congenital candidosis
SNOMED CT: Congenital candidiasis (276672007); Congenital candidosis (276672007)
 
Monarch Initiative: MONDO:0023415

Definition

A fungal infection by any of the Candida species that is present at birth. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCongenital candidiasis

Professional guidelines

PubMed

Opportunistic invasive fungal infections: diagnosis & clinical management.
Badiee P, Hashemizadeh Z
Indian J Med Res 2014 Feb;139(2):195-204. PMID: 24718393Free PMC Article
Successful caspofungin treatment of multidrug resistant Candida parapsilosis septicaemia in an extremely low birth weight neonate.
Yalaz M, Akisu M, Hilmioglu S, Calkavur S, Cakmak B, Kultursay N
Mycoses 2006 May;49(3):242-5. doi: 10.1111/j.1439-0507.2006.01220.x. PMID: 16681818
Treatment of human immunodeficiencies.
Parkman R
Clin Immunol Rev 1981-1982;1(3):375-408. PMID: 6819914

Recent clinical studies

Etiology

Congenital candidiasis as a subject of research in medicine and human ecology.
Skoczylas MM, Walat A, Kordek A, Loniewska B, Rudnicki J, Maleszka R, Torbé A
Ann Parasitol 2014;60(3):179-89. PMID: 25281815
Neonatal cutaneous fungal infections.
Smolinski KN, Shah SS, Honig PJ, Yan AC
Curr Opin Pediatr 2005 Aug;17(4):486-93. doi: 10.1097/01.mop.0000171320.91677.55. PMID: 16012261
Mucocutaneous candidiasis.
Rowen JL
Semin Perinatol 2003 Oct;27(5):406-13. doi: 10.1016/s0146-0005(03)00066-1. PMID: 14626505
Congenital candidiasis.
Khambadkone SM, Dixit KM, Divekar A, Joshi SM, Irani SF, Desai M
Indian Pediatr 1996 Jun;33(6):512-6. PMID: 8979616
Congenital candidiasis limited to the nail plates.
Arbegast KD, Lamberty LF, Koh JK, Pergram JM, Braddock SW
Pediatr Dermatol 1990 Dec;7(4):310-2. doi: 10.1111/j.1525-1470.1990.tb01033.x. PMID: 2080127

Diagnosis

Congenital candidiasis.
Wang SM, Hsu CH, Chang JH
Pediatr Neonatol 2008 Jun;49(3):94-6. doi: 10.1016/S1875-9572(08)60020-0. PMID: 18947006
Mucocutaneous candidiasis.
Rowen JL
Semin Perinatol 2003 Oct;27(5):406-13. doi: 10.1016/s0146-0005(03)00066-1. PMID: 14626505
Candida funisitis: A clinicopathologic study of 32 cases.
Qureshi F, Jacques SM, Bendon RW, Faye-Peterson OM, Heifetz SA, Redline R, Sander CM
Pediatr Dev Pathol 1998 Mar-Apr;1(2):118-24. doi: 10.1007/s100249900014. PMID: 9507035
Distinguishing vesicular and pustular disorders in the neonate.
Wagner A
Curr Opin Pediatr 1997 Aug;9(4):396-405. doi: 10.1097/00008480-199708000-00015. PMID: 9300198
Cutaneous congenital candidiasis: a case report.
Gibney MD, Siegfried EC
Pediatr Dermatol 1995 Dec;12(4):359-63. doi: 10.1111/j.1525-1470.1995.tb00202.x. PMID: 8747587

Therapy

Onychodystrophy as the only sign of congenital candidiasis.
Joy Way Bueno SM, Santos Muñoz A, Maldonado I, Larralde M
Pediatr Dermatol 2020 Jan;37(1):159-161. Epub 2019 Oct 20 doi: 10.1111/pde.14021. PMID: 31630427
Skin rash in a preterm infant: when to treat?
Kewley KA, Yajamanyam PK
Arch Dis Child Fetal Neonatal Ed 2018 Mar;103(2):F177. Epub 2017 Dec 7 doi: 10.1136/archdischild-2017-314237. PMID: 29217693
Congenital candidiasis: an uncommon skin eruption presenting at birth.
Siriratsivawong R, Pavlis M, Hymes SR, Mintzer JP
Cutis 2014 May;93(5):229-32. PMID: 24897134
Cutaneous congenital candidiasis in a full-term newborn from an asymptomatic mother.
Torres-Alvarez B, Hernandez-Blanco D, Ehnis-Perez A, Castanedo-Cazares JP
Dermatol Online J 2013 Jul 14;19(7):18967. PMID: 24010513
Congenital candidiasis.
Johnson DE, Thompson TR, Ferrieri P
Am J Dis Child 1981 Mar;135(3):273-5. doi: 10.1001/archpedi.1981.02130270065023. PMID: 7211787

Prognosis

Skin rash in a preterm infant: when to treat?
Kewley KA, Yajamanyam PK
Arch Dis Child Fetal Neonatal Ed 2018 Mar;103(2):F177. Epub 2017 Dec 7 doi: 10.1136/archdischild-2017-314237. PMID: 29217693
Genetic diversity among Candida albicans isolates associated with vertical transmission in preterm triplets.
Hoarau G, Bougnoux ME, Fily A, François N, Loridant S, Jawhara S, d'Enfert C, Poulain D, Sendid B
Mycopathologia 2014 Oct;178(3-4):285-90. Epub 2014 Aug 24 doi: 10.1007/s11046-014-9803-z. PMID: 25151365
Congenital candidiasis presenting as septic shock without rash.
Carmo KB, Evans N, Isaacs D
Arch Dis Child 2007 Jul;92(7):627-8. Epub 2007 Jan 18 doi: 10.1136/adc.2007.115865. PMID: 17234655Free PMC Article
Candida funisitis: A clinicopathologic study of 32 cases.
Qureshi F, Jacques SM, Bendon RW, Faye-Peterson OM, Heifetz SA, Redline R, Sander CM
Pediatr Dev Pathol 1998 Mar-Apr;1(2):118-24. doi: 10.1007/s100249900014. PMID: 9507035
Congenital candidiasis.
Khambadkone SM, Dixit KM, Divekar A, Joshi SM, Irani SF, Desai M
Indian Pediatr 1996 Jun;33(6):512-6. PMID: 8979616

Clinical prediction guides

Congenital candidiasis in a full-term infant: A case report.
Zhao HH, Zhe-Zhou, Lu L, Zhao YZ, Yang LJ, Ding YX
J Int Med Res 2023 Apr;51(4):3000605231158015. doi: 10.1177/03000605231158015. PMID: 37062969Free PMC Article
Congenital systemic candidiasis: a comprehensive literature review and meta-analysis of 44 cases.
Georgescu TA, Lisievici AC, Munteanu O, Furtunescu FL, Bratu OG, Berceanu C, Bohîlţea RE
Rom J Morphol Embryol 2020 Jul-Sep;61(3):673-680. doi: 10.47162/RJME.61.3.05. PMID: 33817708Free PMC Article
Congenital candidiasis as a subject of research in medicine and human ecology.
Skoczylas MM, Walat A, Kordek A, Loniewska B, Rudnicki J, Maleszka R, Torbé A
Ann Parasitol 2014;60(3):179-89. PMID: 25281815
Invasive candidiasis in low birth weight preterm infants: risk factors, clinical course and outcome in a prospective multicenter study of cases and their matched controls.
Barton M, O'Brien K, Robinson JL, Davies DH, Simpson K, Asztalos E, Langley JM, Le Saux N, Sauve R, Synnes A, Tan B, de Repentigny L, Rubin E, Hui C, Kovacs L, Richardson SE
BMC Infect Dis 2014 Jun 12;14:327. doi: 10.1186/1471-2334-14-327. PMID: 24924877Free PMC Article
Congenital candidiasis.
Wang SM, Hsu CH, Chang JH
Pediatr Neonatol 2008 Jun;49(3):94-6. doi: 10.1016/S1875-9572(08)60020-0. PMID: 18947006

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