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Hypertensive encephalopathy

MedGen UID:
57726
•Concept ID:
C0151620
•
Disease or Syndrome
Synonyms: Encephalopathy, Hypertensive; Hypertensive Encephalopathy
SNOMED CT: Hypertensive encephalopathy (50490005)
 
Monarch Initiative: MONDO:0006796

Definition

Encephalopathy resulting from hypertension. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypertensive encephalopathy

Professional guidelines

PubMed

Etiology, Diagnosis and Management of Aortitis.
Sharma S, Pandey NN, Sinha M, Chandrashekhara SH
Cardiovasc Intervent Radiol 2020 Dec;43(12):1821-1836. Epub 2020 May 10 doi: 10.1007/s00270-020-02486-6. PMID: 32390100
Posterior reversible encephalopathy syndrome--Insight into pathogenesis, clinical variants and treatment approaches.
Granata G, Greco A, Iannella G, Granata M, Manno A, Savastano E, Magliulo G
Autoimmun Rev 2015 Sep;14(9):830-6. Epub 2015 May 18 doi: 10.1016/j.autrev.2015.05.006. PMID: 25999210
Diagnosis, prevention, and management of eclampsia.
Sibai BM
Obstet Gynecol 2005 Feb;105(2):402-10. doi: 10.1097/01.AOG.0000152351.13671.99. PMID: 15684172

Recent clinical studies

Etiology

Posterior Reversible Encephalopathy Syndrome.
Gewirtz AN, Gao V, Parauda SC, Robbins MS
Curr Pain Headache Rep 2021 Feb 25;25(3):19. doi: 10.1007/s11916-020-00932-1. PMID: 33630183Free PMC Article
Hypertensive emergencies and urgencies in emergency departments: a systematic review and meta-analysis.
Astarita A, Covella M, Vallelonga F, Cesareo M, Totaro S, Ventre L, Aprà F, Veglio F, Milan A
J Hypertens 2020 Jul;38(7):1203-1210. doi: 10.1097/HJH.0000000000002372. PMID: 32510905
Scleroderma renal crisis.
Mouthon L, Bussone G, Berezné A, Noël LH, Guillevin L
J Rheumatol 2014 Jun;41(6):1040-8. Epub 2014 May 15 doi: 10.3899/jrheum.131210. PMID: 24833760
Hypertension and hypertensive encephalopathy.
Price RS, Kasner SE
Handb Clin Neurol 2014;119:161-7. doi: 10.1016/B978-0-7020-4086-3.00012-6. PMID: 24365295
Stroke chameleons.
Dupre CM, Libman R, Dupre SI, Katz JM, Rybinnik I, Kwiatkowski T
J Stroke Cerebrovasc Dis 2014 Feb;23(2):374-8. Epub 2013 Aug 15 doi: 10.1016/j.jstrokecerebrovasdis.2013.07.015. PMID: 23954604

Diagnosis

Management of hypertensive crisis: British and Irish Hypertension Society Position document.
Kulkarni S, Glover M, Kapil V, Abrams SML, Partridge S, McCormack T, Sever P, Delles C, Wilkinson IB
J Hum Hypertens 2023 Oct;37(10):863-879. Epub 2022 Nov 22 doi: 10.1038/s41371-022-00776-9. PMID: 36418425Free PMC Article
Posterior Reversible Encephalopathy Syndrome.
Gewirtz AN, Gao V, Parauda SC, Robbins MS
Curr Pain Headache Rep 2021 Feb 25;25(3):19. doi: 10.1007/s11916-020-00932-1. PMID: 33630183Free PMC Article
Posterior reversible encephalopathy syndrome.
Fischer M, Schmutzhard E
J Neurol 2017 Aug;264(8):1608-1616. Epub 2017 Jan 4 doi: 10.1007/s00415-016-8377-8. PMID: 28054130Free PMC Article
Hemolytic uremic syndrome.
Webster K, Schnitzler E
Handb Clin Neurol 2014;120:1113-23. doi: 10.1016/B978-0-7020-4087-0.00075-9. PMID: 24365375
A reversible posterior leukoencephalopathy syndrome.
Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin MS, Lamy C, Mas JL, Caplan LR
N Engl J Med 1996 Feb 22;334(8):494-500. doi: 10.1056/NEJM199602223340803. PMID: 8559202

Therapy

Management of hypertensive crisis: British and Irish Hypertension Society Position document.
Kulkarni S, Glover M, Kapil V, Abrams SML, Partridge S, McCormack T, Sever P, Delles C, Wilkinson IB
J Hum Hypertens 2023 Oct;37(10):863-879. Epub 2022 Nov 22 doi: 10.1038/s41371-022-00776-9. PMID: 36418425Free PMC Article
Hypertensive emergencies and urgencies in emergency departments: a systematic review and meta-analysis.
Astarita A, Covella M, Vallelonga F, Cesareo M, Totaro S, Ventre L, Aprà F, Veglio F, Milan A
J Hypertens 2020 Jul;38(7):1203-1210. doi: 10.1097/HJH.0000000000002372. PMID: 32510905
Scleroderma renal crisis.
Mouthon L, Bussone G, Berezné A, Noël LH, Guillevin L
J Rheumatol 2014 Jun;41(6):1040-8. Epub 2014 May 15 doi: 10.3899/jrheum.131210. PMID: 24833760
Hypertension crisis.
Papadopoulos DP, Mourouzis I, Thomopoulos C, Makris T, Papademetriou V
Blood Press 2010 Dec;19(6):328-36. Epub 2010 May 27 doi: 10.3109/08037051.2010.488052. PMID: 20504242
A reversible posterior leukoencephalopathy syndrome.
Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin MS, Lamy C, Mas JL, Caplan LR
N Engl J Med 1996 Feb 22;334(8):494-500. doi: 10.1056/NEJM199602223340803. PMID: 8559202

Prognosis

Characteristics and Prognosis of Patients With Hypertensive Encephalopathy: A French Nationwide Cohort Study.
Halimi JM, de Fréminville JB, Gatault P, Bisson A, Sautenet B, Maisons V, Vigny P, Angoulvant D, Fauchier L
Hypertension 2023 Aug;80(8):1716-1727. Epub 2023 Jun 7 doi: 10.1161/HYPERTENSIONAHA.123.21226. PMID: 37283073
Posterior Reversible Encephalopathy Syndrome.
Gewirtz AN, Gao V, Parauda SC, Robbins MS
Curr Pain Headache Rep 2021 Feb 25;25(3):19. doi: 10.1007/s11916-020-00932-1. PMID: 33630183Free PMC Article
Hypertensive emergencies and urgencies in emergency departments: a systematic review and meta-analysis.
Astarita A, Covella M, Vallelonga F, Cesareo M, Totaro S, Ventre L, Aprà F, Veglio F, Milan A
J Hypertens 2020 Jul;38(7):1203-1210. doi: 10.1097/HJH.0000000000002372. PMID: 32510905
Posterior reversible encephalopathy syndrome.
Fischer M, Schmutzhard E
J Neurol 2017 Aug;264(8):1608-1616. Epub 2017 Jan 4 doi: 10.1007/s00415-016-8377-8. PMID: 28054130Free PMC Article
Scleroderma renal crisis.
Mouthon L, Bussone G, Berezné A, Noël LH, Guillevin L
J Rheumatol 2014 Jun;41(6):1040-8. Epub 2014 May 15 doi: 10.3899/jrheum.131210. PMID: 24833760

Clinical prediction guides

Characteristics and Prognosis of Patients With Hypertensive Encephalopathy: A French Nationwide Cohort Study.
Halimi JM, de Fréminville JB, Gatault P, Bisson A, Sautenet B, Maisons V, Vigny P, Angoulvant D, Fauchier L
Hypertension 2023 Aug;80(8):1716-1727. Epub 2023 Jun 7 doi: 10.1161/HYPERTENSIONAHA.123.21226. PMID: 37283073
Hypertensive emergencies and urgencies in emergency departments: a systematic review and meta-analysis.
Astarita A, Covella M, Vallelonga F, Cesareo M, Totaro S, Ventre L, Aprà F, Veglio F, Milan A
J Hypertens 2020 Jul;38(7):1203-1210. doi: 10.1097/HJH.0000000000002372. PMID: 32510905
Peak blood pressure and prediction of posterior reversible encephalopathy syndrome in children.
Gall E, Chaudhuri A, South AM
Pediatr Nephrol 2020 Oct;35(10):1967-1975. Epub 2020 May 8 doi: 10.1007/s00467-020-04577-5. PMID: 32385528Free PMC Article
Stroke chameleons.
Dupre CM, Libman R, Dupre SI, Katz JM, Rybinnik I, Kwiatkowski T
J Stroke Cerebrovasc Dis 2014 Feb;23(2):374-8. Epub 2013 Aug 15 doi: 10.1016/j.jstrokecerebrovasdis.2013.07.015. PMID: 23954604
The management of hypertensive crises: a clinical review.
Pergolini MS
Clin Ter 2009;160(2):151-7. PMID: 19452106

Recent systematic reviews

Posterior reversible leukoencephalopathy syndrome associated with acute postinfectious glomerulonephritis: systematic review.
Orlando C, Milani GP, Simonetti GD, Goeggel Simonetti B, Lava SAG, Wyttenbach R, Bianchetti MG, Cristallo Lacalamita M
Pediatr Nephrol 2022 Apr;37(4):833-841. Epub 2021 Sep 21 doi: 10.1007/s00467-021-05244-z. PMID: 34546419Free PMC Article
Hypertensive emergencies and urgencies in emergency departments: a systematic review and meta-analysis.
Astarita A, Covella M, Vallelonga F, Cesareo M, Totaro S, Ventre L, Aprà F, Veglio F, Milan A
J Hypertens 2020 Jul;38(7):1203-1210. doi: 10.1097/HJH.0000000000002372. PMID: 32510905
Pharmacological interventions for hypertensive emergencies: a Cochrane systematic review.
Perez MI, Musini VM
J Hum Hypertens 2008 Sep;22(9):596-607. Epub 2008 Apr 17 doi: 10.1038/jhh.2008.25. PMID: 18418399

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