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Benign neoplasm of tonsil

MedGen UID:
57804
Concept ID:
C0153936
Neoplastic Process
Synonyms: Benign neoplasm of palatine tonsil; Benign Neoplasm of the Tonsil; benign neoplasm of the tonsil; Benign Neoplasm of Tonsil; benign neoplasm of tonsil; Benign Tonsil Neoplasm; benign tonsil neoplasm; Benign Tonsil Tumor; benign tonsil tumor; benign tonsil tumour; Benign Tonsillar Neoplasm; benign tonsillar neoplasm; Benign Tonsillar Tumor; benign tonsillar tumor; benign tonsillar tumour; Benign tumor of faucial tonsil; Benign tumor of palatine tonsil; Benign Tumor of the Tonsil; benign tumor of the tonsil; Benign tumor of tonsil; Benign Tumor of Tonsil; benign tumor of tonsil; benign tumour of the tonsil; benign tumour of tonsil; tonsil benign neoplasm; Tonsillar Neoplasm, Benign; tonsillar neoplasm, benign
SNOMED CT: Benign neoplasm of tonsil (92263001); Benign neoplasm of palatine tonsil (92263001); Benign tumor of palatine tonsil (92263001); Benign tumor of faucial tonsil (92263001); Benign tumor of tonsil (92263001)
 
Monarch Initiative: MONDO:0021513

Definition

A neoplasm that arises from the tonsil and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of tonsil

Professional guidelines

PubMed

Henry M
Curr Oncol 2023 Jul 19;30(7):6859-6861. doi: 10.3390/curroncol30070501. PMID: 37504361Free PMC Article
Kim D, Siegel J, Chouake RJ, Geliebter J, Zalvan CH
Ear Nose Throat J 2021 Aug;100(7):546-551. Epub 2019 Oct 3 doi: 10.1177/0145561319871228. PMID: 31581834
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Recent clinical studies

Etiology

Kamiński B
J Cancer Res Ther 2021 Oct-Dec;17(6):1347-1350. doi: 10.4103/jcrt.JCRT_213_20. PMID: 34916364
Combes JD, Voisin N, Périé S, Malard O, Jegoux F, Nadjingar R, Buiret G, Philouze P, Garrel R, Vergez S, Fakhry N, Righini C, Mirghani H, Lerat J, Saroul N, Verillaud B, Bartaire E, Céruse P, Clifford GM, Franceschi S, Lacau St Guily J
Oral Oncol 2021 Jun;117:105302. Epub 2021 Apr 24 doi: 10.1016/j.oraloncology.2021.105302. PMID: 33905915
Fugl A, Andersen CL
BMC Fam Pract 2019 May 14;20(1):62. doi: 10.1186/s12875-019-0954-3. PMID: 31088382Free PMC Article
Wei PY, Chu CH, Wang MC
Auris Nasus Larynx 2018 Jun;45(3):514-516. Epub 2017 Jul 25 doi: 10.1016/j.anl.2017.07.004. PMID: 28754260
Foppoli M, Ferreri AJ
Eur J Haematol 2015 Mar;94(3):206-18. Epub 2014 Oct 1 doi: 10.1111/ejh.12439. PMID: 25154298

Diagnosis

Auerbach A, Schmieg JJ, Aguilera NS
Head Neck Pathol 2021 Mar;15(1):41-58. Epub 2021 Mar 15 doi: 10.1007/s12105-020-01257-6. PMID: 33723759Free PMC Article
Parvin S, Ramirez-Labrada A, Aumann S, Lu X, Weich N, Santiago G, Cortizas EM, Sharabi E, Zhang Y, Sanchez-Garcia I, Gentles AJ, Roberts E, Bilbao-Cortes D, Vega F, Chapman JR, Verdun RE, Lossos IS
Cancer Cell 2019 Sep 16;36(3):237-249.e6. Epub 2019 Aug 22 doi: 10.1016/j.ccell.2019.07.007. PMID: 31447348Free PMC Article
Fugl A, Andersen CL
BMC Fam Pract 2019 May 14;20(1):62. doi: 10.1186/s12875-019-0954-3. PMID: 31088382Free PMC Article
Foppoli M, Ferreri AJ
Eur J Haematol 2015 Mar;94(3):206-18. Epub 2014 Oct 1 doi: 10.1111/ejh.12439. PMID: 25154298
Rockson SG
Lymphat Res Biol 2010 Jun;8(2):101. doi: 10.1089/lrb.2010.8203. PMID: 20583871

Therapy

Yang W, Yang Y, Guo Y, Guo J, Ma M, Han B
Front Endocrinol (Lausanne) 2023;14:1197730. Epub 2023 Aug 29 doi: 10.3389/fendo.2023.1197730. PMID: 37711902Free PMC Article
Mehanna H, Taberna M, von Buchwald C, Tous S, Brooks J, Mena M, Morey F, Grønhøj C, Rasmussen JH, Garset-Zamani M, Bruni L, Batis N, Brakenhoff RH, Leemans CR, Baatenburg de Jong RJ, Klussmann JP, Wuerdemann N, Wagner S, Dalianis T, Marklund L, Mirghani H, Schache A, James JA, Huang SH, O'Sullivan B, Nankivell P, Broglie MA, Hoffmann M, Quabius ES, Alemany L; HNCIG-EPIC group
Lancet Oncol 2023 Mar;24(3):239-251. Epub 2023 Feb 13 doi: 10.1016/S1470-2045(23)00013-X. PMID: 36796393
Parvin S, Ramirez-Labrada A, Aumann S, Lu X, Weich N, Santiago G, Cortizas EM, Sharabi E, Zhang Y, Sanchez-Garcia I, Gentles AJ, Roberts E, Bilbao-Cortes D, Vega F, Chapman JR, Verdun RE, Lossos IS
Cancer Cell 2019 Sep 16;36(3):237-249.e6. Epub 2019 Aug 22 doi: 10.1016/j.ccell.2019.07.007. PMID: 31447348Free PMC Article
Voudouri D, Nikolaou V, Laschos K, Charpidou A, Soupos N, Triantafyllopoulou I, Panoutsopoulou I, Aravantinos G, Syrigos K, Stratigos A
Curr Probl Cancer 2017 Nov-Dec;41(6):407-412. Epub 2017 Oct 18 doi: 10.1016/j.currproblcancer.2017.10.003. PMID: 29096940
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Prognosis

Kamiński B
J Cancer Res Ther 2021 Oct-Dec;17(6):1347-1350. doi: 10.4103/jcrt.JCRT_213_20. PMID: 34916364
Parvin S, Ramirez-Labrada A, Aumann S, Lu X, Weich N, Santiago G, Cortizas EM, Sharabi E, Zhang Y, Sanchez-Garcia I, Gentles AJ, Roberts E, Bilbao-Cortes D, Vega F, Chapman JR, Verdun RE, Lossos IS
Cancer Cell 2019 Sep 16;36(3):237-249.e6. Epub 2019 Aug 22 doi: 10.1016/j.ccell.2019.07.007. PMID: 31447348Free PMC Article
Andor N, Simonds EF, Czerwinski DK, Chen J, Grimes SM, Wood-Bouwens C, Zheng GXY, Kubit MA, Greer S, Weiss WA, Levy R, Ji HP
Blood 2019 Mar 7;133(10):1119-1129. Epub 2018 Dec 27 doi: 10.1182/blood-2018-08-862292. PMID: 30591526Free PMC Article
Forman D, de Martel C, Lacey CJ, Soerjomataram I, Lortet-Tieulent J, Bruni L, Vignat J, Ferlay J, Bray F, Plummer M, Franceschi S
Vaccine 2012 Nov 20;30 Suppl 5:F12-23. doi: 10.1016/j.vaccine.2012.07.055. PMID: 23199955
Marur S, D'Souza G, Westra WH, Forastiere AA
Lancet Oncol 2010 Aug;11(8):781-9. Epub 2010 May 5 doi: 10.1016/S1470-2045(10)70017-6. PMID: 20451455Free PMC Article

Clinical prediction guides

Holló G
Immunol Res 2021 Dec;69(6):467-470. Epub 2021 Sep 15 doi: 10.1007/s12026-021-09230-3. PMID: 34523058Free PMC Article
Köbel M, Kang EY
Int J Gynecol Pathol 2021 Jan;40(1):32-40. doi: 10.1097/PGP.0000000000000725. PMID: 33290354
Parvin S, Ramirez-Labrada A, Aumann S, Lu X, Weich N, Santiago G, Cortizas EM, Sharabi E, Zhang Y, Sanchez-Garcia I, Gentles AJ, Roberts E, Bilbao-Cortes D, Vega F, Chapman JR, Verdun RE, Lossos IS
Cancer Cell 2019 Sep 16;36(3):237-249.e6. Epub 2019 Aug 22 doi: 10.1016/j.ccell.2019.07.007. PMID: 31447348Free PMC Article
Andor N, Simonds EF, Czerwinski DK, Chen J, Grimes SM, Wood-Bouwens C, Zheng GXY, Kubit MA, Greer S, Weiss WA, Levy R, Ji HP
Blood 2019 Mar 7;133(10):1119-1129. Epub 2018 Dec 27 doi: 10.1182/blood-2018-08-862292. PMID: 30591526Free PMC Article
Marur S, D'Souza G, Westra WH, Forastiere AA
Lancet Oncol 2010 Aug;11(8):781-9. Epub 2010 May 5 doi: 10.1016/S1470-2045(10)70017-6. PMID: 20451455Free PMC Article

Recent systematic reviews

Schuch LF, Schmidt TR, de Oliveira Zigmundo G, Kirschnick LB, Silveira FM, Martins MAT, Carlos R, Dos Santos JN, Fonseca FP, Vargas PA, Wagner VP, Martins MD
Head Neck Pathol 2022 Jun;16(2):525-537. Epub 2021 Dec 6 doi: 10.1007/s12105-021-01398-2. PMID: 34870796Free PMC Article
De Luca P, Tassone D, de Campora L, Simone M, Marra P, Colacurcio V, Scarpa A, Costarelli L, Camaioni A
Eur Arch Otorhinolaryngol 2022 Jun;279(6):2719-2725. Epub 2021 Oct 23 doi: 10.1007/s00405-021-07140-6. PMID: 34687340
Wojtera M, Paradis J, Husein M, Nichols AC, Barrett JW, Salvadori MI, Strychowsky JE
J Otolaryngol Head Neck Surg 2018 Jan 30;47(1):8. doi: 10.1186/s40463-018-0255-1. PMID: 29378664Free PMC Article
Szudek J, Taylor SM
Arch Otolaryngol Head Neck Surg 2007 Jul;133(7):655-61. doi: 10.1001/archotol.133.7.655. PMID: 17638777
Hobbs CG, Sterne JA, Bailey M, Heyderman RS, Birchall MA, Thomas SJ
Clin Otolaryngol 2006 Aug;31(4):259-66. doi: 10.1111/j.1749-4486.2006.01246.x. PMID: 16911640

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