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Retinal vascular disorder

MedGen UID:
57824
•Concept ID:
C0154833
•
Disease or Syndrome
Synonym: Retinal vascular disease
SNOMED CT: Retinal vascular disorder (57534004)
 
Monarch Initiative: MONDO:0002311

Definition

Retinal damage resulting from diminished blood flow/oxygenation due to abnormalities of the retinal vessels. Causes include hypertension, diabetes, thrombosis, embolism, and hemorrhage. [from NCI]

Professional guidelines

PubMed

Coats disease: An overview of classification, management and outcomes.
Sen M, Shields CL, Honavar SG, Shields JA
Indian J Ophthalmol 2019 Jun;67(6):763-771. doi: 10.4103/ijo.IJO_841_19. PMID: 31124484Free PMC Article
Surgical Management of Coats Disease.
Kusaka S
Asia Pac J Ophthalmol (Phila) 2018 May-Jun;7(3):156-159. Epub 2018 Mar 27 doi: 10.22608/APO.201867. PMID: 29664241
Best practices for treatment of retinal vein occlusion.
Hahn P, Fekrat S
Curr Opin Ophthalmol 2012 May;23(3):175-81. doi: 10.1097/ICU.0b013e3283524148. PMID: 22450223

Recent clinical studies

Etiology

Vascular abnormalities in fellow eyes of patients with unilateral coats' disease.
Lee SM, Kim KH, Kang HG, Choi EY, Lee J, Kim M
Sci Rep 2023 Nov 8;13(1):19380. doi: 10.1038/s41598-023-45838-1. PMID: 37938623Free PMC Article
Incidence of Retinal Artery Occlusion and Related Mortality in Korea, 2005 to 2018.
Hwang DD, Lee KE, Kim Y, Kim MS, Rim TH, Kim M, Kim H, Kyoung DS, Park JI
JAMA Netw Open 2023 Mar 1;6(3):e233068. doi: 10.1001/jamanetworkopen.2023.3068. PMID: 36897587
Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors.
Song P, Xu Y, Zha M, Zhang Y, Rudan I
J Glob Health 2019 Jun;9(1):010427. doi: 10.7189/jogh.09.010427. PMID: 31131101Free PMC Article
Investigational drugs for retinal vein occlusion.
Bremond-Gignac D
Expert Opin Investig Drugs 2016 Jul;25(7):841-50. Epub 2016 May 9 doi: 10.1080/13543784.2016.1181750. PMID: 27153189
Branch retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complications. An update of the literature.
Jaulim A, Ahmed B, Khanam T, Chatziralli IP
Retina 2013 May;33(5):901-10. doi: 10.1097/IAE.0b013e3182870c15. PMID: 23609064

Diagnosis

Incidence of Retinal Artery Occlusion and Related Mortality in Korea, 2005 to 2018.
Hwang DD, Lee KE, Kim Y, Kim MS, Rim TH, Kim M, Kim H, Kyoung DS, Park JI
JAMA Netw Open 2023 Mar 1;6(3):e233068. doi: 10.1001/jamanetworkopen.2023.3068. PMID: 36897587
Coats disease: An overview of classification, management and outcomes.
Sen M, Shields CL, Honavar SG, Shields JA
Indian J Ophthalmol 2019 Jun;67(6):763-771. doi: 10.4103/ijo.IJO_841_19. PMID: 31124484Free PMC Article
Unilateral retinal venous beading.
Abdel-Hay AF, Raman V
BMJ Case Rep 2018 Dec 3;11(1) doi: 10.1136/bcr-2018-226116. PMID: 30567160Free PMC Article
Intravitreal steroid and anti-vascular endothelial growth agents for the management of retinal vein occlusion: evidence from randomized trials.
Chatziralli I, Nicholson L, Sivaprasad S, Hykin P
Expert Opin Biol Ther 2015;15(12):1685-97. Epub 2015 Sep 11 doi: 10.1517/14712598.2015.1086744. PMID: 26358547
Branch retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complications. An update of the literature.
Jaulim A, Ahmed B, Khanam T, Chatziralli IP
Retina 2013 May;33(5):901-10. doi: 10.1097/IAE.0b013e3182870c15. PMID: 23609064

Therapy

Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors.
Song P, Xu Y, Zha M, Zhang Y, Rudan I
J Glob Health 2019 Jun;9(1):010427. doi: 10.7189/jogh.09.010427. PMID: 31131101Free PMC Article
Investigational drugs for retinal vein occlusion.
Bremond-Gignac D
Expert Opin Investig Drugs 2016 Jul;25(7):841-50. Epub 2016 May 9 doi: 10.1080/13543784.2016.1181750. PMID: 27153189
Clinical Trials in Branch Retinal Vein Occlusion.
Panakanti TK, Chhablani J
Middle East Afr J Ophthalmol 2016 Jan-Mar;23(1):38-43. doi: 10.4103/0974-9233.172294. PMID: 26957837Free PMC Article
Central retinal vein occlusion: modifying current treatment protocols.
Ashraf M, Souka AA, Singh RP
Eye (Lond) 2016 Apr;30(4):505-14. Epub 2016 Feb 12 doi: 10.1038/eye.2016.10. PMID: 26869163Free PMC Article
Intravitreal steroid and anti-vascular endothelial growth agents for the management of retinal vein occlusion: evidence from randomized trials.
Chatziralli I, Nicholson L, Sivaprasad S, Hykin P
Expert Opin Biol Ther 2015;15(12):1685-97. Epub 2015 Sep 11 doi: 10.1517/14712598.2015.1086744. PMID: 26358547

Prognosis

Incidence of Retinal Artery Occlusion and Related Mortality in Korea, 2005 to 2018.
Hwang DD, Lee KE, Kim Y, Kim MS, Rim TH, Kim M, Kim H, Kyoung DS, Park JI
JAMA Netw Open 2023 Mar 1;6(3):e233068. doi: 10.1001/jamanetworkopen.2023.3068. PMID: 36897587
Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors.
Song P, Xu Y, Zha M, Zhang Y, Rudan I
J Glob Health 2019 Jun;9(1):010427. doi: 10.7189/jogh.09.010427. PMID: 31131101Free PMC Article
Central retinal vein occlusion: modifying current treatment protocols.
Ashraf M, Souka AA, Singh RP
Eye (Lond) 2016 Apr;30(4):505-14. Epub 2016 Feb 12 doi: 10.1038/eye.2016.10. PMID: 26869163Free PMC Article
Intravitreal steroid and anti-vascular endothelial growth agents for the management of retinal vein occlusion: evidence from randomized trials.
Chatziralli I, Nicholson L, Sivaprasad S, Hykin P
Expert Opin Biol Ther 2015;15(12):1685-97. Epub 2015 Sep 11 doi: 10.1517/14712598.2015.1086744. PMID: 26358547
Current therapy for retinal vein occlusion.
Cernak M, Struharova K
Bratisl Lek Listy 2012;113(4):228-31. doi: 10.4149/bll_2012_052. PMID: 22502754

Clinical prediction guides

Vitamin B12 levels in patients with retinal vein occlusion and their relation with clinical outcome: a retrospective study.
Paciullo F, Menduno PS, Tucci D, Caricato A, Cagini C, Gresele P
Intern Emerg Med 2022 Jun;17(4):1065-1071. Epub 2022 Jan 14 doi: 10.1007/s11739-021-02905-7. PMID: 35028874
Central retinal vein occlusion: modifying current treatment protocols.
Ashraf M, Souka AA, Singh RP
Eye (Lond) 2016 Apr;30(4):505-14. Epub 2016 Feb 12 doi: 10.1038/eye.2016.10. PMID: 26869163Free PMC Article
Branch retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complications. An update of the literature.
Jaulim A, Ahmed B, Khanam T, Chatziralli IP
Retina 2013 May;33(5):901-10. doi: 10.1097/IAE.0b013e3182870c15. PMID: 23609064
Best practices for treatment of retinal vein occlusion.
Hahn P, Fekrat S
Curr Opin Ophthalmol 2012 May;23(3):175-81. doi: 10.1097/ICU.0b013e3283524148. PMID: 22450223
Central retinal vein occlusion with cilioretinal infarction from branch flow exclusion and choroidal arterial steal.
McLeod D
Retina 2009 Nov-Dec;29(10):1381-95. doi: 10.1097/IAE.0b013e3181b85f41. PMID: 19898176

Recent systematic reviews

Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors.
Song P, Xu Y, Zha M, Zhang Y, Rudan I
J Glob Health 2019 Jun;9(1):010427. doi: 10.7189/jogh.09.010427. PMID: 31131101Free PMC Article
Anti-vascular endothelial growth factor for macular oedema secondary to central retinal vein occlusion.
Braithwaite T, Nanji AA, Lindsley K, Greenberg PB
Cochrane Database Syst Rev 2014 May 1;2014(5):CD007325. doi: 10.1002/14651858.CD007325.pub3. PMID: 24788977Free PMC Article
Anti-vascular endothelial growth factor for macular edema secondary to central retinal vein occlusion.
Braithwaite T, Nanji AA, Greenberg PB
Cochrane Database Syst Rev 2010 Oct 6;(10):CD007325. doi: 10.1002/14651858.CD007325.pub2. PMID: 20927757Free PMC Article

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