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Suprasellar Germ Cell Tumor

MedGen UID:
578843
•Concept ID:
C0349615
•
Neoplastic Process
Synonym: Suprasellar germ cell tumor
SNOMED CT: Suprasellar germ cell tumor (277456001)

Definition

A germ cell tumor that arises from the suprasellar region. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSuprasellar Germ Cell Tumor

Professional guidelines

PubMed

Recovery of hypothalamus-pituitary-gonadal dysfunction after the treatment of suprasellar germ cell tumors.
Zhang K, Wang L, Duan L, Yang H, Pan H, Lian X, Yao Y, Zhu H
Eur J Endocrinol 2021 Apr;184(4):617-625. doi: 10.1530/EJE-20-1310. PMID: 33524006

Recent clinical studies

Etiology

Recovery of hypothalamus-pituitary-gonadal dysfunction after the treatment of suprasellar germ cell tumors.
Zhang K, Wang L, Duan L, Yang H, Pan H, Lian X, Yao Y, Zhu H
Eur J Endocrinol 2021 Apr;184(4):617-625. doi: 10.1530/EJE-20-1310. PMID: 33524006
Cerebral Sinovenous Thrombosis and Subdural Hematoma as Treatment-Related Complications in Suprasellar Germ Cell Tumor Associated with Adipsic Diabetes Insipidus.
Kobayashi K, Suehiro M, Maihara T, Usami I, Kageyama Y, Okazaki S, Heike T
Pediatr Neurosurg 2019;54(4):288-292. Epub 2019 Jul 10 doi: 10.1159/000501044. PMID: 31291634
Pretreatment diagnosis of suprasellar papillary craniopharyngioma and germ cell tumors of adult patients.
Lee HJ, Wu CC, Wu HM, Hung SC, Lirng JF, Luo CB, Chang FC, Guo WY
AJNR Am J Neuroradiol 2015 Mar;36(3):508-17. Epub 2014 Oct 22 doi: 10.3174/ajnr.A4142. PMID: 25339645Free PMC Article
Suprasellar germ cell tumor with subarachnoid seeding MRI and MR spectroscopy findings.
Kendi TK, Caglar S, Huvaj S, Bademci G, Kendi M, Alparslan S
Clin Imaging 2004 Nov-Dec;28(6):404-7. doi: 10.1016/S0899-7071(03)00315-2. PMID: 15531139
Homozygous p53 gene mutation in a radiation-induced glioblastoma 10 years after treatment for an intracranial germ cell tumor: case report.
Tada M, Sawamura Y, Abe H, Iggo R
Neurosurgery 1997 Feb;40(2):393-6. doi: 10.1097/00006123-199702000-00034. PMID: 9007876

Diagnosis

Recovery of hypothalamus-pituitary-gonadal dysfunction after the treatment of suprasellar germ cell tumors.
Zhang K, Wang L, Duan L, Yang H, Pan H, Lian X, Yao Y, Zhu H
Eur J Endocrinol 2021 Apr;184(4):617-625. doi: 10.1530/EJE-20-1310. PMID: 33524006
Pretreatment diagnosis of suprasellar papillary craniopharyngioma and germ cell tumors of adult patients.
Lee HJ, Wu CC, Wu HM, Hung SC, Lirng JF, Luo CB, Chang FC, Guo WY
AJNR Am J Neuroradiol 2015 Mar;36(3):508-17. Epub 2014 Oct 22 doi: 10.3174/ajnr.A4142. PMID: 25339645Free PMC Article
Suprasellar germ cell tumor with subarachnoid seeding MRI and MR spectroscopy findings.
Kendi TK, Caglar S, Huvaj S, Bademci G, Kendi M, Alparslan S
Clin Imaging 2004 Nov-Dec;28(6):404-7. doi: 10.1016/S0899-7071(03)00315-2. PMID: 15531139
Gonadotropin releasing hormone-independent precocious puberty in a 5 year-old girl with suprasellar germ cell tumor secreting beta-hCG and alpha-fetoprotein.
Starzyk J, Starzyk B, Bartnik-Mikuta A, Urbanowicz W, Dziatkowiak H
J Pediatr Endocrinol Metab 2001 Jun;14(6):789-96. doi: 10.1515/jpem.2001.14.6.789. PMID: 11453531
Metachronous ovarian dysgerminoma after a suprasellar germ-cell tumor treated by radiation therapy. Case report.
Watanabe T, Makiyama Y, Nishimoto H, Matsumoto M, Kikuchi A, Tsubokawa T
J Neurosurg 1995 Jul;83(1):149-53. doi: 10.3171/jns.1995.83.1.0149. PMID: 7782834

Prognosis

Multiple Tumor-Associated Intracranial Aneurysms Adjacent to a Suprasellar Germ Cell Tumor: Case Report and Review of Literature.
Yue JK, Chang D, Oh T, Winkler EA, Lu AY, Hetts SW, Young EP, Reddy AT, Fox CK, Abla AA, Roland JL
Pediatr Neurosurg 2021;56(5):482-491. Epub 2021 Jul 28 doi: 10.1159/000517890. PMID: 34320494
Recovery of hypothalamus-pituitary-gonadal dysfunction after the treatment of suprasellar germ cell tumors.
Zhang K, Wang L, Duan L, Yang H, Pan H, Lian X, Yao Y, Zhu H
Eur J Endocrinol 2021 Apr;184(4):617-625. doi: 10.1530/EJE-20-1310. PMID: 33524006
Suprasellar germ cell tumor with subarachnoid seeding MRI and MR spectroscopy findings.
Kendi TK, Caglar S, Huvaj S, Bademci G, Kendi M, Alparslan S
Clin Imaging 2004 Nov-Dec;28(6):404-7. doi: 10.1016/S0899-7071(03)00315-2. PMID: 15531139
Homozygous p53 gene mutation in a radiation-induced glioblastoma 10 years after treatment for an intracranial germ cell tumor: case report.
Tada M, Sawamura Y, Abe H, Iggo R
Neurosurgery 1997 Feb;40(2):393-6. doi: 10.1097/00006123-199702000-00034. PMID: 9007876
Metachronous ovarian dysgerminoma after a suprasellar germ-cell tumor treated by radiation therapy. Case report.
Watanabe T, Makiyama Y, Nishimoto H, Matsumoto M, Kikuchi A, Tsubokawa T
J Neurosurg 1995 Jul;83(1):149-53. doi: 10.3171/jns.1995.83.1.0149. PMID: 7782834

Clinical prediction guides

Recovery of hypothalamus-pituitary-gonadal dysfunction after the treatment of suprasellar germ cell tumors.
Zhang K, Wang L, Duan L, Yang H, Pan H, Lian X, Yao Y, Zhu H
Eur J Endocrinol 2021 Apr;184(4):617-625. doi: 10.1530/EJE-20-1310. PMID: 33524006
Gonadotropin releasing hormone-independent precocious puberty in a 5 year-old girl with suprasellar germ cell tumor secreting beta-hCG and alpha-fetoprotein.
Starzyk J, Starzyk B, Bartnik-Mikuta A, Urbanowicz W, Dziatkowiak H
J Pediatr Endocrinol Metab 2001 Jun;14(6):789-96. doi: 10.1515/jpem.2001.14.6.789. PMID: 11453531
Homozygous p53 gene mutation in a radiation-induced glioblastoma 10 years after treatment for an intracranial germ cell tumor: case report.
Tada M, Sawamura Y, Abe H, Iggo R
Neurosurgery 1997 Feb;40(2):393-6. doi: 10.1097/00006123-199702000-00034. PMID: 9007876

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