U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Bipolar depression

MedGen UID:
585
Concept ID:
C0005587
Mental or Behavioral Dysfunction
Synonyms: Bipolar Depression; Depression, Bipolar
SNOMED CT: Bipolar affective disorder, current episode depression (191627008); Manic-depressive - now depressed (191627008)
 
Monarch Initiative: MONDO:0024613

Definition

The depressive stage of bipolar disorder. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBipolar depression

Professional guidelines

PubMed

Goes FS
BMJ 2023 Apr 12;381:e073591. doi: 10.1136/bmj-2022-073591. PMID: 37045450
Mutz J
Bipolar Disord 2023 Feb;25(1):9-24. Epub 2022 Dec 21 doi: 10.1111/bdi.13283. PMID: 36515461Free PMC Article
Dubovsky SL, Ghosh BM, Serotte JC, Cranwell V
Psychother Psychosom 2021;90(3):160-177. Epub 2020 Nov 9 doi: 10.1159/000511348. PMID: 33166960

Recent clinical studies

Etiology

Yildiz A, Siafis S, Mavridis D, Vieta E, Leucht S
Lancet Psychiatry 2023 Sep;10(9):693-705. doi: 10.1016/S2215-0366(23)00199-2. PMID: 37595997
Siegel-Ramsay JE, Bertocci MA, Wu B, Phillips ML, Strakowski SM, Almeida JRC
Bipolar Disord 2022 Aug;24(5):474-498. Epub 2022 Jan 30 doi: 10.1111/bdi.13176. PMID: 35060259
Arnold I, Dehning J, Grunze A, Hausmann A
Medicina (Kaunas) 2021 Jun 8;57(6) doi: 10.3390/medicina57060587. PMID: 34201098Free PMC Article
Bahji A, Ermacora D, Stephenson C, Hawken ER, Vazquez G
J Affect Disord 2020 May 15;269:154-184. Epub 2020 Mar 20 doi: 10.1016/j.jad.2020.03.030. PMID: 32339131
McIntyre RS, Calabrese JR
Curr Med Res Opin 2019 Nov;35(11):1993-2005. Epub 2019 Aug 5 doi: 10.1080/03007995.2019.1636017. PMID: 31311335

Diagnosis

Lane NM, Smith DJ
J R Coll Physicians Edinb 2023 Sep;53(3):192-196. Epub 2023 Aug 30 doi: 10.1177/14782715231197577. PMID: 37649414
Siegel-Ramsay JE, Bertocci MA, Wu B, Phillips ML, Strakowski SM, Almeida JRC
Bipolar Disord 2022 Aug;24(5):474-498. Epub 2022 Jan 30 doi: 10.1111/bdi.13176. PMID: 35060259
Fountoulakis KN, Tohen M, Zarate CA Jr
Eur Neuropsychopharmacol 2022 Jan;54:100-115. doi: 10.1016/j.euroneuro.2021.10.003. PMID: 34980362Free PMC Article
Dubovsky SL, Ghosh BM, Serotte JC, Cranwell V
Psychother Psychosom 2021;90(3):160-177. Epub 2020 Nov 9 doi: 10.1159/000511348. PMID: 33166960
McIntyre RS, Calabrese JR
Curr Med Res Opin 2019 Nov;35(11):1993-2005. Epub 2019 Aug 5 doi: 10.1080/03007995.2019.1636017. PMID: 31311335

Therapy

Fountoulakis KN, Tohen M, Zarate CA Jr
Eur Neuropsychopharmacol 2022 Jan;54:100-115. doi: 10.1016/j.euroneuro.2021.10.003. PMID: 34980362Free PMC Article
Bahji A, Ermacora D, Stephenson C, Hawken ER, Vazquez G
J Affect Disord 2020 May 15;269:154-184. Epub 2020 Mar 20 doi: 10.1016/j.jad.2020.03.030. PMID: 32339131
Corriger A, Pickering G
Drug Des Devel Ther 2019;13:3051-3067. Epub 2019 Aug 27 doi: 10.2147/DDDT.S221437. PMID: 31695324Free PMC Article
Perugi G, Vannucchi G, Bedani F, Favaretto E
Curr Psychiatry Rep 2017 Jan;19(1):7. doi: 10.1007/s11920-017-0758-x. PMID: 28144880
Fagiolini A, Coluccia A, Maina G, Forgione RN, Goracci A, Cuomo A, Young AH
CNS Drugs 2015 Sep;29(9):725-40. doi: 10.1007/s40263-015-0275-6. PMID: 26369921

Prognosis

Lane NM, Smith DJ
J R Coll Physicians Edinb 2023 Sep;53(3):192-196. Epub 2023 Aug 30 doi: 10.1177/14782715231197577. PMID: 37649414
Goes FS
BMJ 2023 Apr 12;381:e073591. doi: 10.1136/bmj-2022-073591. PMID: 37045450
Dubovsky SL, Ghosh BM, Serotte JC, Cranwell V
Psychother Psychosom 2021;90(3):160-177. Epub 2020 Nov 9 doi: 10.1159/000511348. PMID: 33166960
Gold AK, Kinrys G
Curr Psychiatry Rep 2019 Mar 2;21(3):14. doi: 10.1007/s11920-019-1001-8. PMID: 30826893Free PMC Article
Tondo L, Vázquez GH, Baldessarini RJ
Curr Neuropharmacol 2017 Apr;15(3):353-358. doi: 10.2174/1570159X14666160606210811. PMID: 28503106Free PMC Article

Clinical prediction guides

Zengin G, Topak OZ, Atesci O, Culha Atesci F
Psychiatr Danub 2022 Summer;34(2):236-244. doi: 10.24869/psyd.2022.236. PMID: 35772133
Kadakia A, Dembek C, Heller V, Singh R, Uyei J, Hagi K, Nosaka T, Loebel A
BMC Psychiatry 2021 May 11;21(1):249. doi: 10.1186/s12888-021-03220-3. PMID: 33975574Free PMC Article
Mazza M, Marano G, Traversi G, Carocci V, Romano B, Janiri L
CNS Neurol Disord Drug Targets 2018;17(10):723-727. doi: 10.2174/1871527317666180828120256. PMID: 30152291
Alberich S, Martínez-Cengotitabengoa M, López P, Zorrilla I, Núñez N, Vieta E, González-Pinto A
Rev Psiquiatr Salud Ment 2017 Apr-Jun;10(2):104-112. Epub 2016 Jul 5 doi: 10.1016/j.rpsm.2016.05.005. PMID: 27387226
Geddes JR, Briess D
BMJ Clin Evid 2007 Aug 1;2007 PMID: 19454110Free PMC Article

Recent systematic reviews

Yildiz A, Siafis S, Mavridis D, Vieta E, Leucht S
Lancet Psychiatry 2023 Sep;10(9):693-705. doi: 10.1016/S2215-0366(23)00199-2. PMID: 37595997
Meshkat S, Haikazian S, Di Vincenzo JD, Fancy F, Johnson D, Chen-Li D, McIntyre RS, Mansur R, Rosenblat JD
World J Biol Psychiatry 2023 Sep-Oct;24(7):545-557. Epub 2023 Jan 31 doi: 10.1080/15622975.2023.2169349. PMID: 36651238
Moncrieff J, Cooper RE, Stockmann T, Amendola S, Hengartner MP, Horowitz MA
Mol Psychiatry 2023 Aug;28(8):3243-3256. Epub 2022 Jul 20 doi: 10.1038/s41380-022-01661-0. PMID: 35854107Free PMC Article
Fountoulakis KN, Tohen M, Zarate CA Jr
Eur Neuropsychopharmacol 2022 Jan;54:100-115. doi: 10.1016/j.euroneuro.2021.10.003. PMID: 34980362Free PMC Article
Pacchiarotti I, Tiihonen J, Kotzalidis GD, Verdolini N, Murru A, Goikolea JM, Valentí M, Aedo A, Vieta E
Eur Neuropsychopharmacol 2019 Apr;29(4):457-470. Epub 2019 Feb 12 doi: 10.1016/j.euroneuro.2019.02.003. PMID: 30770235

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...