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Dialysis disequilibrium syndrome

MedGen UID:
588475
Concept ID:
C0403559
Disease or Syndrome
Synonyms: Dialysis disequilibrium; Dialysis Disequilibrium Syndrome; Disequilibrium Syndrome
SNOMED CT: Dialysis disequilibrium syndrome (87235005); Dialysis disequilibrium (87235005)

Definition

A complication occurring during hemodialysis that is thought to be due to a rapid decrease in blood urea nitrogen, and is characterized by an increase in intracranial pressure resulting in nausea, headache, vomiting, restlessness, and/or a decreased level of consciousness. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDialysis disequilibrium syndrome

Professional guidelines

PubMed

Acharya H, Tennant SM, Yip K
Emerg Med Pract 2024 Jul;26(7):1-24. Epub 2024 Jul 1 PMID: 38904942
Yessayan LT, Szamosfalvi B, Rosner MH
Semin Dial 2021 Nov;34(6):472-479. Epub 2021 Jul 3 doi: 10.1111/sdi.12983. PMID: 34218456
Saha M, Allon M
Clin J Am Soc Nephrol 2017 Feb 7;12(2):357-369. Epub 2016 Nov 9 doi: 10.2215/CJN.05260516. PMID: 27831511Free PMC Article

Recent clinical studies

Etiology

Husain-Syed F, Takeuchi T, Neyra JA, Ramírez-Guerrero G, Rosner MH, Ronco C, Tolwani AJ
Crit Care 2023 Sep 3;27(1):341. doi: 10.1186/s13054-023-04632-1. PMID: 37661277Free PMC Article
Parsons AD, Sanscrainte C, Leone A, Griepp DW, Rahme R
World Neurosurg 2023 Feb;170:2-6. Epub 2022 Dec 6 doi: 10.1016/j.wneu.2022.11.142. PMID: 36494069
Raina R, Davenport A, Warady B, Vasistha P, Sethi SK, Chakraborty R, Khooblall P, Agarwal N, Vij M, Schaefer F, Malhotra K, Misra M
Pediatr Nephrol 2022 Feb;37(2):263-274. Epub 2021 Oct 5 doi: 10.1007/s00467-021-05242-1. PMID: 34609583
Genena KH, Ahmed S, Szerlip HM, Schwartz JC
Hemodial Int 2021 Oct;25(4):424-432. Epub 2021 Jun 18 doi: 10.1111/hdi.12938. PMID: 34145961
Lin CM, Lin JW, Tsai JT, Ko CP, Hung KS, Hung CC, Su YK, Wei L, Chiu WT, Lee LM
Acta Neurochir Suppl 2008;101:141-4. doi: 10.1007/978-3-211-78205-7_24. PMID: 18642649

Diagnosis

Tadevosyan A, Kornbluth J
Neurol Clin 2021 May;39(2):293-318. Epub 2021 Mar 31 doi: 10.1016/j.ncl.2021.02.005. PMID: 33896520
Hocker SE
Continuum (Minneap Minn) 2017 Jun;23(3, Neurology of Systemic Disease):722-743. doi: 10.1212/CON.0000000000000469. PMID: 28570326
Saha M, Allon M
Clin J Am Soc Nephrol 2017 Feb 7;12(2):357-369. Epub 2016 Nov 9 doi: 10.2215/CJN.05260516. PMID: 27831511Free PMC Article
Patel N, Dalal P, Panesar M
Semin Dial 2008 Sep-Oct;21(5):493-8. Epub 2008 Aug 28 doi: 10.1111/j.1525-139X.2008.00474.x. PMID: 18764799
Bagshaw SM, Peets AD, Hameed M, Boiteau PJ, Laupland KB, Doig CJ
BMC Nephrol 2004 Aug 19;5:9. doi: 10.1186/1471-2369-5-9. PMID: 15318947Free PMC Article

Therapy

Greenberg KI, Choi MJ
Am J Kidney Dis 2021 May;77(5):796-809. Epub 2021 Mar 23 doi: 10.1053/j.ajkd.2020.11.024. PMID: 33771393
Saha M, Allon M
Clin J Am Soc Nephrol 2017 Feb 7;12(2):357-369. Epub 2016 Nov 9 doi: 10.2215/CJN.05260516. PMID: 27831511Free PMC Article
Zepeda-Orozco D, Quigley R
Pediatr Nephrol 2012 Dec;27(12):2205-11. Epub 2012 Jun 19 doi: 10.1007/s00467-012-2199-4. PMID: 22710692Free PMC Article
Patel N, Dalal P, Panesar M
Semin Dial 2008 Sep-Oct;21(5):493-8. Epub 2008 Aug 28 doi: 10.1111/j.1525-139X.2008.00474.x. PMID: 18764799
Nissenson AR, Weston RE, Kleeman CR
West J Med 1979 Oct;131(4):277-84. PMID: 388867Free PMC Article

Prognosis

Vigil D, Kien C, Gibb J, Glew RH, Tzamaloukas AH
Am J Med Sci 2019 Jun;357(6):512-516. Epub 2019 Feb 27 doi: 10.1016/j.amjms.2019.02.016. PMID: 30975430
Mah DY, Yia HJ, Cheong WS
Med J Malaysia 2016 Apr;71(2):91-2. PMID: 27326954
Tsai WC, Chen JC, Tsao YT
Am J Emerg Med 2015 Apr;33(4):602.e3-4. Epub 2014 Oct 11 doi: 10.1016/j.ajem.2014.09.030. PMID: 25308826
Osgood M, Compton R, Carandang R, Hall W, Kershaw G, Muehlschlegel S
Neurocrit Care 2015 Apr;22(2):176-83. doi: 10.1007/s12028-014-0064-y. PMID: 25228117
Agraharkar M, Martinez MA, Kuo YF, Ahuja TS
Nephron Clin Pract 2004;97(2):c54-60. doi: 10.1159/000078401. PMID: 15230279

Clinical prediction guides

Ishizaki Y, Nishizono R, Kikuchi M, Inagaki H, Sato Y, Fujimoto S
F1000Res 2020;9:969. Epub 2020 Aug 11 doi: 10.12688/f1000research.25597.3. PMID: 34868569Free PMC Article
Vigil D, Kien C, Gibb J, Glew RH, Tzamaloukas AH
Am J Med Sci 2019 Jun;357(6):512-516. Epub 2019 Feb 27 doi: 10.1016/j.amjms.2019.02.016. PMID: 30975430
Mah DY, Yia HJ, Cheong WS
Med J Malaysia 2016 Apr;71(2):91-2. PMID: 27326954
Lin CM, Lin JW, Tsai JT, Ko CP, Hung KS, Hung CC, Su YK, Wei L, Chiu WT, Lee LM
Acta Neurochir Suppl 2008;101:141-4. doi: 10.1007/978-3-211-78205-7_24. PMID: 18642649
Silver SM, Sterns RH, Halperin ML
Am J Kidney Dis 1996 Jul;28(1):1-13. doi: 10.1016/s0272-6386(96)90124-9. PMID: 8712203

Recent systematic reviews

Parsons AD, Sanscrainte C, Leone A, Griepp DW, Rahme R
World Neurosurg 2023 Feb;170:2-6. Epub 2022 Dec 6 doi: 10.1016/j.wneu.2022.11.142. PMID: 36494069
Raina R, Davenport A, Warady B, Vasistha P, Sethi SK, Chakraborty R, Khooblall P, Agarwal N, Vij M, Schaefer F, Malhotra K, Misra M
Pediatr Nephrol 2022 Feb;37(2):263-274. Epub 2021 Oct 5 doi: 10.1007/s00467-021-05242-1. PMID: 34609583

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