U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Acquired testicular failure

MedGen UID:
588672
•Concept ID:
C0403818
•
Disease or Syndrome
Synonyms: Acquired Testicular Failure; acquired testicular failure
SNOMED CT: Acquired testicular failure (236811002)
 
Monarch Initiative: MONDO:0023554

Definition

Testicular failure, the cause of which is not present at birth. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcquired testicular failure

Professional guidelines

PubMed

The urological management of the patient with acquired immunodeficiency syndrome.
Heyns CF, Fisher M
BJU Int 2005 Apr;95(5):709-16. doi: 10.1111/j.1464-410X.2004.05435.x. PMID: 15784082
Criteria predicting the absence of spermatozoa in the Sertoli cell-only syndrome can be used to improve success rates of sperm retrieval.
Anniballo R, Ubaldi F, Cobellis L, Sorrentino M, Rienzi L, Greco E, Tesarik J
Hum Reprod 2000 Nov;15(11):2269-77. doi: 10.1093/humrep/15.11.2269. PMID: 11056118

Recent clinical studies

Etiology

Subclinical male hypogonadism.
Corona G, Rastrelli G, Dicuio M, Concetti S, Minnetti M, Pivonello R, Isidori A, Sforza A, Maggi M
Minerva Endocrinol (Torino) 2021 Sep;46(3):252-261. Epub 2020 Sep 24 doi: 10.23736/S2724-6507.20.03208-3. PMID: 32969626
Clinical and spermatological findings in male dogs with acquired infertility: A retrospective analysis.
Domosławska A, Zdunczyk S
Andrologia 2020 Dec;52(11):e13802. Epub 2020 Aug 24 doi: 10.1111/and.13802. PMID: 32835435
Hypotestosteronaemia in the aging male: should we treat it?
Christe N, Meier CA
Swiss Med Wkly 2015;145:w14216. Epub 2015 Nov 24 doi: 10.4414/smw.2015.14216. PMID: 26599486
Testicular tissue cryopreservation and spermatogonial stem cell transplantation to restore fertility: from bench to bedside.
Sadri-Ardekani H, Atala A
Stem Cell Res Ther 2014 May 28;5(3):68. doi: 10.1186/scrt457. PMID: 25157677Free PMC Article
The urological management of the patient with acquired immunodeficiency syndrome.
Heyns CF, Fisher M
BJU Int 2005 Apr;95(5):709-16. doi: 10.1111/j.1464-410X.2004.05435.x. PMID: 15784082

Diagnosis

Clinical and spermatological findings in male dogs with acquired infertility: A retrospective analysis.
Domosławska A, Zdunczyk S
Andrologia 2020 Dec;52(11):e13802. Epub 2020 Aug 24 doi: 10.1111/and.13802. PMID: 32835435
Inactivation of REV7 enhances chemosensitivity and overcomes acquired chemoresistance in testicular germ cell tumors.
Sakurai Y, Ichinoe M, Yoshida K, Nakazato Y, Saito S, Satoh M, Nakada N, Sanoyama I, Umezawa A, Numata Y, Shi-Xu J, Ichihara M, Takahashi M, Murakumo Y
Cancer Lett 2020 Oct 1;489:100-110. Epub 2020 Jun 15 doi: 10.1016/j.canlet.2020.06.001. PMID: 32553781
Hypotestosteronaemia in the aging male: should we treat it?
Christe N, Meier CA
Swiss Med Wkly 2015;145:w14216. Epub 2015 Nov 24 doi: 10.4414/smw.2015.14216. PMID: 26599486
Biochemical endocrinology of the hypogonadal male.
Belchetz PE, Barth JH, Kaufman JM
Ann Clin Biochem 2010 Nov;47(Pt 6):503-15. Epub 2010 Oct 18 doi: 10.1258/acb.2010.010150. PMID: 20956400
Genetics of human male infertility.
Poongothai J, Gopenath TS, Manonayaki S
Singapore Med J 2009 Apr;50(4):336-47. PMID: 19421675

Therapy

Subclinical male hypogonadism.
Corona G, Rastrelli G, Dicuio M, Concetti S, Minnetti M, Pivonello R, Isidori A, Sforza A, Maggi M
Minerva Endocrinol (Torino) 2021 Sep;46(3):252-261. Epub 2020 Sep 24 doi: 10.23736/S2724-6507.20.03208-3. PMID: 32969626
Hypotestosteronaemia in the aging male: should we treat it?
Christe N, Meier CA
Swiss Med Wkly 2015;145:w14216. Epub 2015 Nov 24 doi: 10.4414/smw.2015.14216. PMID: 26599486
Genetics of human male infertility.
Poongothai J, Gopenath TS, Manonayaki S
Singapore Med J 2009 Apr;50(4):336-47. PMID: 19421675
Testosterone therapy--what, when and to whom?
Jockenhövel F
Aging Male 2004 Dec;7(4):319-24. doi: 10.1080/13685530400016557. PMID: 15799128
Testicular findings, endocrine features and therapeutic responses of men with acquired hypogonadotropic hypogonadism.
Tachiki H, Ito N, Maruta H, Kumamoto Y, Tsukamoto T
Int J Urol 1998 Jan;5(1):80-5. doi: 10.1111/j.1442-2042.1998.tb00244.x. PMID: 9535606

Prognosis

Identification and functional analysis of spermatogenesis-associated gene modules in azoospermia by weighted gene coexpression network analysis.
Zheng W, Zou Z, Lin S, Chen X, Wang F, Li X, Dai J
J Cell Biochem 2019 Mar;120(3):3934-3944. Epub 2018 Sep 30 doi: 10.1002/jcb.27677. PMID: 30269365
En bloc mobilization of the pancreas and spleen to facilitate resection of large tumors, primarily renal and adrenal, in the left upper quadrant of the abdomen: techniques derived from multivisceral transplantation.
Ciancio G, Vaidya A, Shirodkar S, Manoharan M, Hakky T, Soloway M
Eur Urol 2009 May;55(5):1106-11. Epub 2009 Jan 9 doi: 10.1016/j.eururo.2008.12.038. PMID: 19167808
The urological management of the patient with acquired immunodeficiency syndrome.
Heyns CF, Fisher M
BJU Int 2005 Apr;95(5):709-16. doi: 10.1111/j.1464-410X.2004.05435.x. PMID: 15784082
Criteria predicting the absence of spermatozoa in the Sertoli cell-only syndrome can be used to improve success rates of sperm retrieval.
Anniballo R, Ubaldi F, Cobellis L, Sorrentino M, Rienzi L, Greco E, Tesarik J
Hum Reprod 2000 Nov;15(11):2269-77. doi: 10.1093/humrep/15.11.2269. PMID: 11056118
Testicular failure in patients with extragonadal germ cell tumors.
Carroll PR, Whitmore WF Jr, Richardson M, Bajorunas D, Herr HW, Williams RD, Fair WR, Chaganti RS
Cancer 1987 Jul 1;60(1):108-13. doi: 10.1002/1097-0142(19870701)60:1<108::aid-cncr2820600120>3.0.co;2-8. PMID: 3034394

Clinical prediction guides

Identification and functional analysis of spermatogenesis-associated gene modules in azoospermia by weighted gene coexpression network analysis.
Zheng W, Zou Z, Lin S, Chen X, Wang F, Li X, Dai J
J Cell Biochem 2019 Mar;120(3):3934-3944. Epub 2018 Sep 30 doi: 10.1002/jcb.27677. PMID: 30269365
Early prediction of treatment response to high-dose salvage chemotherapy in patients with relapsed germ cell cancer using [(18)F]FDG PET.
Bokemeyer C, Kollmannsberger C, Oechsle K, Dohmen BM, Pfannenberg A, Claussen CD, Bares R, Kanz L
Br J Cancer 2002 Feb 12;86(4):506-11. doi: 10.1038/sj.bjc.6600122. PMID: 11870528Free PMC Article
Criteria predicting the absence of spermatozoa in the Sertoli cell-only syndrome can be used to improve success rates of sperm retrieval.
Anniballo R, Ubaldi F, Cobellis L, Sorrentino M, Rienzi L, Greco E, Tesarik J
Hum Reprod 2000 Nov;15(11):2269-77. doi: 10.1093/humrep/15.11.2269. PMID: 11056118
Acquired undescended testis.
Zhou Y, Takahashi G, Kono S, Takemura H, Shinagawa T
Int J Urol 1998 Sep;5(5):504-6. doi: 10.1111/j.1442-2042.1998.tb00402.x. PMID: 9781446
Incomplete disappearance of the processus vaginalis as a cause of ascending testis.
Clarnette TD, Rowe D, Hasthorpe S, Hutson JM
J Urol 1997 May;157(5):1889-91. PMID: 9112556

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...