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Irritable bowel syndrome

MedGen UID:
5897
Concept ID:
C0022104
Disease or Syndrome
Synonyms: Colitides, Mucous; Colitis, Mucous; Colon, Irritable; Irritable Bowel Syndrome; Irritable Bowel Syndromes; Irritable Colon; Mucous Colitides; Mucous Colitis; Syndrome, Irritable Bowel; Syndromes, Irritable Bowel
SNOMED CT: Colon spasm (10743008); Functional bowel disease (10743008); Nervous colitis (10743008); IBS - Irritable bowel syndrome (10743008); Irritable bowel (10743008); Spastic colitis (10743008); Irritable colon syndrome (10743008); IC - Irritable colon (10743008); Irritable colon (10743008); Adaptive colitis (10743008); Membranous colitis (10743008); Spastic colon (10743008); Irritable bowel syndrome (10743008); Mucous colitis (10743008)
 
Monarch Initiative: MONDO:0005052

Definition

Gastrointestinal symptoms characterized by chronic abdominal pain and altered bowel habits in the absence of any organic cause. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIrritable bowel syndrome

Professional guidelines

PubMed

Camilleri M
JAMA 2021 Mar 2;325(9):865-877. doi: 10.1001/jama.2020.22532. PMID: 33651094
Lacy BE, Pimentel M, Brenner DM, Chey WD, Keefer LA, Long MD, Moshiree B
Am J Gastroenterol 2021 Jan 1;116(1):17-44. doi: 10.14309/ajg.0000000000001036. PMID: 33315591
Camilleri M
Mayo Clin Proc 2018 Dec;93(12):1858-1872. doi: 10.1016/j.mayocp.2018.04.032. PMID: 30522596Free PMC Article

Recent clinical studies

Etiology

Galica AN, Galica R, Dumitrașcu DL
J Med Life 2022 Feb;15(2):174-179. doi: 10.25122/jml-2022-0028. PMID: 35419092Free PMC Article
Sebastián Domingo JJ
Med Clin (Barc) 2022 Jan 21;158(2):76-81. Epub 2021 Jul 6 doi: 10.1016/j.medcli.2021.04.029. PMID: 34238582
Ford AC, Sperber AD, Corsetti M, Camilleri M
Lancet 2020 Nov 21;396(10263):1675-1688. Epub 2020 Oct 10 doi: 10.1016/S0140-6736(20)31548-8. PMID: 33049223
Radovanovic-Dinic B, Tesic-Rajkovic S, Grgov S, Petrovic G, Zivkovic V
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2018 Mar;162(1):1-9. Epub 2018 Jan 18 doi: 10.5507/bp.2017.057. PMID: 29358788
Saha L
World J Gastroenterol 2014 Jun 14;20(22):6759-73. doi: 10.3748/wjg.v20.i22.6759. PMID: 24944467Free PMC Article

Diagnosis

Sebastián Domingo JJ
Med Clin (Barc) 2022 Jan 21;158(2):76-81. Epub 2021 Jul 6 doi: 10.1016/j.medcli.2021.04.029. PMID: 34238582
Adriani A, Ribaldone DG, Astegiano M, Durazzo M, Saracco GM, Pellicano R
Panminerva Med 2018 Dec;60(4):213-222. Epub 2018 Sep 24 doi: 10.23736/S0031-0808.18.03541-3. PMID: 30257542
Radovanovic-Dinic B, Tesic-Rajkovic S, Grgov S, Petrovic G, Zivkovic V
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2018 Mar;162(1):1-9. Epub 2018 Jan 18 doi: 10.5507/bp.2017.057. PMID: 29358788
Defrees DN, Bailey J
Prim Care 2017 Dec;44(4):655-671. Epub 2017 Oct 5 doi: 10.1016/j.pop.2017.07.009. PMID: 29132527
Saha L
World J Gastroenterol 2014 Jun 14;20(22):6759-73. doi: 10.3748/wjg.v20.i22.6759. PMID: 24944467Free PMC Article

Therapy

Vasant DH, Paine PA, Black CJ, Houghton LA, Everitt HA, Corsetti M, Agrawal A, Aziz I, Farmer AD, Eugenicos MP, Moss-Morris R, Yiannakou Y, Ford AC
Gut 2021 Jul;70(7):1214-1240. Epub 2021 Apr 26 doi: 10.1136/gutjnl-2021-324598. PMID: 33903147
Black CJ, Thakur ER, Houghton LA, Quigley EMM, Moayyedi P, Ford AC
Gut 2020 Aug;69(8):1441-1451. Epub 2020 Apr 10 doi: 10.1136/gutjnl-2020-321191. PMID: 32276950
D'Silva A, MacQueen G, Nasser Y, Taylor LM, Vallance JK, Raman M
Dig Dis Sci 2020 Sep;65(9):2503-2514. Epub 2019 Dec 12 doi: 10.1007/s10620-019-05989-6. PMID: 31832970
Ooijevaar RE, Terveer EM, Verspaget HW, Kuijper EJ, Keller JJ
Annu Rev Med 2019 Jan 27;70:335-351. Epub 2018 Nov 7 doi: 10.1146/annurev-med-111717-122956. PMID: 30403550
Staudacher HM, Whelan K
Gut 2017 Aug;66(8):1517-1527. Epub 2017 Jun 7 doi: 10.1136/gutjnl-2017-313750. PMID: 28592442

Prognosis

Golla R, Vuyyuru S, Kante B, Kumar P, Thomas DM, Makharia G, Kedia S, Ahuja V
Clin Gastroenterol Hepatol 2023 Mar;21(3):789-796.e1. Epub 2022 Oct 21 doi: 10.1016/j.cgh.2022.10.015. PMID: 36273799Free PMC Article
Wu S, Yuan C, Liu S, Zhang Q, Yang Z, Sun F, Zhan S, Zhu S, Zhang S
Am J Gastroenterol 2022 May 1;117(5):785-793. Epub 2022 Feb 3 doi: 10.14309/ajg.0000000000001674. PMID: 35130187
Ghoshal UC, Ghoshal U, Rahman MM, Mathur A, Rai S, Akhter M, Mostafa T, Islam MS, Haque SA, Pandey A, Kibria MG, Ahmed F
J Gastroenterol Hepatol 2022 Mar;37(3):489-498. Epub 2021 Nov 4 doi: 10.1111/jgh.15717. PMID: 34672022Free PMC Article
Chiaffarino F, Cipriani S, Ricci E, Mauri PA, Esposito G, Barretta M, Vercellini P, Parazzini F
Arch Gynecol Obstet 2021 Jan;303(1):17-25. Epub 2020 Sep 19 doi: 10.1007/s00404-020-05797-8. PMID: 32949284
Francavilla R, Piccolo M, Francavilla A, Polimeno L, Semeraro F, Cristofori F, Castellaneta S, Barone M, Indrio F, Gobbetti M, De Angelis M
J Clin Gastroenterol 2019 Mar;53(3):e117-e125. doi: 10.1097/MCG.0000000000001023. PMID: 29688915Free PMC Article

Clinical prediction guides

Nee J, Ballou S, Kelley JM, Kaptchuk TJ, Hirsch W, Katon J, Cheng V, Rangan V, Lembo A, Iturrino J
Am J Gastroenterol 2021 Nov 1;116(11):2279-2285. doi: 10.14309/ajg.0000000000001395. PMID: 34319275
Myneedu K, Deoker A, Schmulson MJ, Bashashati M
United European Gastroenterol J 2019 Oct;7(8):1033-1041. Epub 2019 Jul 30 doi: 10.1177/2050640619866990. PMID: 31662860Free PMC Article
Zhou Q, Verne ML, Fields JZ, Lefante JJ, Basra S, Salameh H, Verne GN
Gut 2019 Jun;68(6):996-1002. Epub 2018 Aug 14 doi: 10.1136/gutjnl-2017-315136. PMID: 30108163Free PMC Article
Deng Y, Misselwitz B, Dai N, Fox M
Nutrients 2015 Sep 18;7(9):8020-35. doi: 10.3390/nu7095380. PMID: 26393648Free PMC Article
Didari T, Mozaffari S, Nikfar S, Abdollahi M
World J Gastroenterol 2015 Mar 14;21(10):3072-84. doi: 10.3748/wjg.v21.i10.3072. PMID: 25780308Free PMC Article

Recent systematic reviews

Zhang T, Zhang C, Zhang J, Sun F, Duan L
Front Cell Infect Microbiol 2022;12:859967. Epub 2022 Apr 1 doi: 10.3389/fcimb.2022.859967. PMID: 35433498Free PMC Article
Black CJ, Staudacher HM, Ford AC
Gut 2022 Jun;71(6):1117-1126. Epub 2021 Aug 10 doi: 10.1136/gutjnl-2021-325214. PMID: 34376515
van Lanen AS, de Bree A, Greyling A
Eur J Nutr 2021 Sep;60(6):3505-3522. Epub 2021 Feb 14 doi: 10.1007/s00394-020-02473-0. PMID: 33585949Free PMC Article
Dale HF, Rasmussen SH, Asiller ÖÖ, Lied GA
Nutrients 2019 Sep 2;11(9) doi: 10.3390/nu11092048. PMID: 31480656Free PMC Article
Ford AC, Harris LA, Lacy BE, Quigley EMM, Moayyedi P
Aliment Pharmacol Ther 2018 Nov;48(10):1044-1060. Epub 2018 Oct 8 doi: 10.1111/apt.15001. PMID: 30294792

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