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Juxtacortical osteosarcoma

MedGen UID:
60197
Concept ID:
C0206642
Neoplastic Process
Synonyms: Juxtacortical Osteosarcoma; Juxtacortical Osteosarcomas; Osteosarcoma, Juxtacortical; Osteosarcomas, Juxtacortical
SNOMED CT: Juxtacortical osteosarcoma (128918008); Parosteal osteosarcoma (128918008); Parosteal osteosarcoma (1290868004)
 
Monarch Initiative: MONDO:0006817

Definition

A low grade malignant bone-forming mesenchymal neoplasm arising from the surface of the bone. It usually affects the distal posterior femur, the proximal tibia, and proximal humerus. Painless swelling is the usual clinical sign. Most patients are young adults and the prognosis is usually excellent. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVJuxtacortical osteosarcoma

Professional guidelines

PubMed

van der Heul RO, von Ronnen JR
J Bone Joint Surg Am 1967 Apr;49(3):415-39. PMID: 5228781

Recent clinical studies

Etiology

Rajakulasingam R, Attard V, Botchu R, James SL, Saifuddin A
Skeletal Radiol 2021 Feb;50(2):301-309. Epub 2020 Jul 23 doi: 10.1007/s00256-020-03557-y. PMID: 32705301
Chen PC, Yen CC, Hung GY, Pan CC, Chen WM
J Chin Med Assoc 2019 Dec;82(12):889-894. doi: 10.1097/JCMA.0000000000000211. PMID: 31634336
Schwab JH, Antonescu CR, Athanasian EA, Boland PJ, Healey JH, Morris CD
Clin Orthop Relat Res 2008 Jun;466(6):1318-22. Epub 2008 Apr 19 doi: 10.1007/s11999-008-0251-2. PMID: 18425560Free PMC Article
Spina V, Montanari N, Romagnoli R
Eur J Radiol 1998 May;27 Suppl 1:S98-109. doi: 10.1016/s0720-048x(98)00050-3. PMID: 9652509
Sheth DS, Yasko AW, Raymond AK, Ayala AG, Carrasco CH, Benjamin RS, Jaffe N, Murray JA
Cancer 1996 Nov 15;78(10):2136-45. PMID: 8918422

Diagnosis

Kresse ME, Kransdorf MJ, Beauchamp CP, Larsen BT, Goulding KA
Skeletal Radiol 2023 Mar;52(3):623-631. Epub 2022 Nov 1 doi: 10.1007/s00256-022-04216-0. PMID: 36318319
Samardziski M, Zafiroski G, Tolevska C, Konstadinova-Kunovska S, Vasilevska V
Bratisl Lek Listy 2009;110(4):240-4. PMID: 19507652
Spina V, Montanari N, Romagnoli R
Eur J Radiol 1998 May;27 Suppl 1:S98-109. doi: 10.1016/s0720-048x(98)00050-3. PMID: 9652509
Griffith JF, Kumta SM, Chow LT, Leung PC, Metreweli C
Skeletal Radiol 1998 Apr;27(4):228-32. doi: 10.1007/s002560050372. PMID: 9592909
Sheth DS, Yasko AW, Raymond AK, Ayala AG, Carrasco CH, Benjamin RS, Jaffe N, Murray JA
Cancer 1996 Nov 15;78(10):2136-45. PMID: 8918422

Therapy

Nodomi S, Umeda K, Okamoto T, Saida S, Hiramatsu H, Watanabe K, Adachi S, Heike T
Pediatr Blood Cancer 2016 Aug;63(8):1471-3. Epub 2016 May 3 doi: 10.1002/pbc.26052. PMID: 27149276
Takeuchi K, Morii T, Yabe H, Morioka H, Mukai M, Toyama Y
Skeletal Radiol 2006 Oct;35(10):778-82. Epub 2006 Mar 1 doi: 10.1007/s00256-005-0066-0. PMID: 16518652
Bertoni F, Bacchini P, Staals EL, Davidovitz P
Cancer 2005 Jun 1;103(11):2373-82. doi: 10.1002/cncr.21039. PMID: 15852358
Wines A, Bonar F, Lam P, McCarthy S, Stalley P
Skeletal Radiol 2000 Oct;29(10):597-600. doi: 10.1007/s002560000247. PMID: 11127684
Lu S, Wang J, Hu Y
Chin Med J (Engl) 1996 Jun;109(6):432-6. PMID: 9206074

Prognosis

Chen PC, Yen CC, Hung GY, Pan CC, Chen WM
J Chin Med Assoc 2019 Dec;82(12):889-894. doi: 10.1097/JCMA.0000000000000211. PMID: 31634336
Rodríguez-Arias CA, Lobato RD, Millán JM, Lagares A, de la Lama A, Alén JF
Neurocirugia (Astur) 2001 Dec;12(6):521-4. doi: 10.1016/s1130-1473(01)70671-9. PMID: 11787402
Spina V, Montanari N, Romagnoli R
Eur J Radiol 1998 May;27 Suppl 1:S98-109. doi: 10.1016/s0720-048x(98)00050-3. PMID: 9652509
Millar BG, Browne RM, Flood TR
Br J Oral Maxillofac Surg 1990 Apr;28(2):73-9. doi: 10.1016/0266-4356(90)90125-5. PMID: 2186801
Levine E, De Smet AA, Huntrakoon M
Skeletal Radiol 1985;14(1):38-46. doi: 10.1007/BF00361191. PMID: 3860961

Clinical prediction guides

Chen PC, Yen CC, Hung GY, Pan CC, Chen WM
J Chin Med Assoc 2019 Dec;82(12):889-894. doi: 10.1097/JCMA.0000000000000211. PMID: 31634336
Han I, Oh JH, Na YG, Moon KC, Kim HS
J Surg Oncol 2008 Feb 1;97(2):146-9. doi: 10.1002/jso.20902. PMID: 18050289
Kaste SC, Fuller CE, Saharia A, Neel MD, Rao BN, Daw NC
Pediatr Blood Cancer 2006 Aug;47(2):152-62. doi: 10.1002/pbc.20570. PMID: 16123997
Johnson K, Davies AM, Evans N, Grimer RJ
Eur Radiol 2001;11(3):460-6. doi: 10.1007/s003300000673. PMID: 11288853
Sheth DS, Yasko AW, Raymond AK, Ayala AG, Carrasco CH, Benjamin RS, Jaffe N, Murray JA
Cancer 1996 Nov 15;78(10):2136-45. PMID: 8918422

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