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excessive bleeding

MedGen UID:
603278
•Concept ID:
C0424561
•
Finding
Synonyms: Bleeds profusely; Excessive Bleeding
SNOMED CT: Bleeds profusely (248252008)

Definition

Abnormally heavy or prolonged loss of blood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVexcessive bleeding

Professional guidelines

PubMed

Clinical Review and Update on the Management of Thyroid Storm.
De Almeida R, McCalmon S, Cabandugama PK
Mo Med 2022 Jul-Aug;119(4):366-371. PMID: 36118802Free PMC Article
Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding.
Wikkelsø A, Wetterslev J, Møller AM, Afshari A
Cochrane Database Syst Rev 2016 Aug 22;2016(8):CD007871. doi: 10.1002/14651858.CD007871.pub3. PMID: 27552162Free PMC Article
ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician-Gynecologists Number 76, October 2006: postpartum hemorrhage.
American College of Obstetricians and Gynecologists
Obstet Gynecol 2006 Oct;108(4):1039-47. doi: 10.1097/00006250-200610000-00046. PMID: 17012482

Recent clinical studies

Etiology

Anticoagulation in Patients with Liver Cirrhosis: Friend or Foe?
Protopapas AA, Savopoulos C, Skoura L, Goulis I
Dig Dis Sci 2023 Jun;68(6):2237-2246. Epub 2023 Mar 24 doi: 10.1007/s10620-023-07858-9. PMID: 36961672Free PMC Article
Managing the coagulopathy associated with cardiopulmonary bypass.
Bartoszko J, Karkouti K
J Thromb Haemost 2021 Mar;19(3):617-632. Epub 2020 Dec 17 doi: 10.1111/jth.15195. PMID: 33251719
Inherited platelet disorders in women.
Gresele P, Falcinelli E, Bury L
Thromb Res 2019 Sep;181 Suppl 1:S54-S59. doi: 10.1016/S0049-3848(19)30368-8. PMID: 31477229
Contemporary Transfusion Science and Challenges.
Passerini HM
AACN Adv Crit Care 2019 Summer;30(2):139-150. doi: 10.4037/aacnacc2019462. PMID: 31151945
ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician-Gynecologists Number 76, October 2006: postpartum hemorrhage.
American College of Obstetricians and Gynecologists
Obstet Gynecol 2006 Oct;108(4):1039-47. doi: 10.1097/00006250-200610000-00046. PMID: 17012482

Diagnosis

Clinical Review and Update on the Management of Thyroid Storm.
De Almeida R, McCalmon S, Cabandugama PK
Mo Med 2022 Jul-Aug;119(4):366-371. PMID: 36118802Free PMC Article
Managing the coagulopathy associated with cardiopulmonary bypass.
Bartoszko J, Karkouti K
J Thromb Haemost 2021 Mar;19(3):617-632. Epub 2020 Dec 17 doi: 10.1111/jth.15195. PMID: 33251719
Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding.
Wikkelsø A, Wetterslev J, Møller AM, Afshari A
Cochrane Database Syst Rev 2016 Aug 22;2016(8):CD007871. doi: 10.1002/14651858.CD007871.pub3. PMID: 27552162Free PMC Article
Excessive uterine bleeding.
Talib HJ, Coupey SM
Adolesc Med State Art Rev 2012 Apr;23(1):53-72. PMID: 22764555
ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician-Gynecologists Number 76, October 2006: postpartum hemorrhage.
American College of Obstetricians and Gynecologists
Obstet Gynecol 2006 Oct;108(4):1039-47. doi: 10.1097/00006250-200610000-00046. PMID: 17012482

Therapy

Managing the coagulopathy associated with cardiopulmonary bypass.
Bartoszko J, Karkouti K
J Thromb Haemost 2021 Mar;19(3):617-632. Epub 2020 Dec 17 doi: 10.1111/jth.15195. PMID: 33251719
Viscoelastic testing in pediatric patients.
Haas T, Faraoni D
Transfusion 2020 Oct;60 Suppl 6:S75-S85. doi: 10.1111/trf.16076. PMID: 33089938
Active versus expectant management for women in the third stage of labour.
Begley CM, Gyte GM, Devane D, McGuire W, Weeks A, Biesty LM
Cochrane Database Syst Rev 2019 Feb 13;2(2):CD007412. doi: 10.1002/14651858.CD007412.pub5. PMID: 30754073Free PMC Article
Frenotomy for tongue-tie in newborn infants.
O'Shea JE, Foster JP, O'Donnell CP, Breathnach D, Jacobs SE, Todd DA, Davis PG
Cochrane Database Syst Rev 2017 Mar 11;3(3):CD011065. doi: 10.1002/14651858.CD011065.pub2. PMID: 28284020Free PMC Article
Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding.
Wikkelsø A, Wetterslev J, Møller AM, Afshari A
Cochrane Database Syst Rev 2016 Aug 22;2016(8):CD007871. doi: 10.1002/14651858.CD007871.pub3. PMID: 27552162Free PMC Article

Prognosis

Anticoagulation in Patients with Liver Cirrhosis: Friend or Foe?
Protopapas AA, Savopoulos C, Skoura L, Goulis I
Dig Dis Sci 2023 Jun;68(6):2237-2246. Epub 2023 Mar 24 doi: 10.1007/s10620-023-07858-9. PMID: 36961672Free PMC Article
Managing the coagulopathy associated with cardiopulmonary bypass.
Bartoszko J, Karkouti K
J Thromb Haemost 2021 Mar;19(3):617-632. Epub 2020 Dec 17 doi: 10.1111/jth.15195. PMID: 33251719
Viscoelastic testing in pediatric patients.
Haas T, Faraoni D
Transfusion 2020 Oct;60 Suppl 6:S75-S85. doi: 10.1111/trf.16076. PMID: 33089938
Inherited platelet disorders in women.
Gresele P, Falcinelli E, Bury L
Thromb Res 2019 Sep;181 Suppl 1:S54-S59. doi: 10.1016/S0049-3848(19)30368-8. PMID: 31477229
Management of bleeding in major burn surgery.
Welling H, Ostrowski SR, Stensballe J, Vestergaard MR, Partoft S, White J, Johansson PI
Burns 2019 Jun;45(4):755-762. Epub 2018 Oct 3 doi: 10.1016/j.burns.2018.08.024. PMID: 30292526

Clinical prediction guides

Managing the coagulopathy associated with cardiopulmonary bypass.
Bartoszko J, Karkouti K
J Thromb Haemost 2021 Mar;19(3):617-632. Epub 2020 Dec 17 doi: 10.1111/jth.15195. PMID: 33251719
Viscoelastic testing in pediatric patients.
Haas T, Faraoni D
Transfusion 2020 Oct;60 Suppl 6:S75-S85. doi: 10.1111/trf.16076. PMID: 33089938
Inherited platelet disorders in women.
Gresele P, Falcinelli E, Bury L
Thromb Res 2019 Sep;181 Suppl 1:S54-S59. doi: 10.1016/S0049-3848(19)30368-8. PMID: 31477229
Management of bleeding in major burn surgery.
Welling H, Ostrowski SR, Stensballe J, Vestergaard MR, Partoft S, White J, Johansson PI
Burns 2019 Jun;45(4):755-762. Epub 2018 Oct 3 doi: 10.1016/j.burns.2018.08.024. PMID: 30292526
Frenotomy for tongue-tie in newborn infants.
O'Shea JE, Foster JP, O'Donnell CP, Breathnach D, Jacobs SE, Todd DA, Davis PG
Cochrane Database Syst Rev 2017 Mar 11;3(3):CD011065. doi: 10.1002/14651858.CD011065.pub2. PMID: 28284020Free PMC Article

Recent systematic reviews

Thrombocytopenia among pregnant women in Africa: a systematic review and meta-analysis.
Getawa S, Getaneh Z, Melku M
Pan Afr Med J 2022;41:334. Epub 2022 Apr 26 doi: 10.11604/pamj.2022.41.334.30175. PMID: 35865846Free PMC Article
Active versus expectant management for women in the third stage of labour.
Begley CM, Gyte GM, Devane D, McGuire W, Weeks A, Biesty LM
Cochrane Database Syst Rev 2019 Feb 13;2(2):CD007412. doi: 10.1002/14651858.CD007412.pub5. PMID: 30754073Free PMC Article
Laparoscopy or laparotomy as the way of entrance in myoma enucleation.
Cezar C, Becker S, di Spiezio Sardo A, Herrmann A, Larbig A, Tanos V, de la Roche LAT, Verhoeven HC, Wallwiener M, De Wilde RL
Arch Gynecol Obstet 2017 Oct;296(4):709-720. Epub 2017 Aug 17 doi: 10.1007/s00404-017-4490-x. PMID: 28819682
Frenotomy for tongue-tie in newborn infants.
O'Shea JE, Foster JP, O'Donnell CP, Breathnach D, Jacobs SE, Todd DA, Davis PG
Cochrane Database Syst Rev 2017 Mar 11;3(3):CD011065. doi: 10.1002/14651858.CD011065.pub2. PMID: 28284020Free PMC Article
Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding.
Wikkelsø A, Wetterslev J, Møller AM, Afshari A
Cochrane Database Syst Rev 2016 Aug 22;2016(8):CD007871. doi: 10.1002/14651858.CD007871.pub3. PMID: 27552162Free PMC Article

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