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excessive bleeding

MedGen UID:
603278
•Concept ID:
C0424561
•
Finding
Synonyms: Bleeds profusely; Excessive Bleeding
SNOMED CT: Bleeds profusely (248252008)

Definition

Abnormally heavy or prolonged loss of blood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVexcessive bleeding

Professional guidelines

PubMed

Clinical Review and Update on the Management of Thyroid Storm.
De Almeida R, McCalmon S, Cabandugama PK
Mo Med 2022 Jul-Aug;119(4):366-371. PMID: 36118802Free PMC Article
Active versus expectant management for women in the third stage of labour.
Begley CM, Gyte GM, Devane D, McGuire W, Weeks A, Biesty LM
Cochrane Database Syst Rev 2019 Feb 13;2(2):CD007412. doi: 10.1002/14651858.CD007412.pub5. PMID: 30754073Free PMC Article
Evaluation and management of abnormal uterine bleeding in premenopausal women.
Sweet MG, Schmidt-Dalton TA, Weiss PM, Madsen KP
Am Fam Physician 2012 Jan 1;85(1):35-43. PMID: 22230306

Recent clinical studies

Etiology

Managing the coagulopathy associated with cardiopulmonary bypass.
Bartoszko J, Karkouti K
J Thromb Haemost 2021 Mar;19(3):617-632. Epub 2020 Dec 17 doi: 10.1111/jth.15195. PMID: 33251719
Evaluation and management of abnormal uterine bleeding in premenopausal women.
Sweet MG, Schmidt-Dalton TA, Weiss PM, Madsen KP
Am Fam Physician 2012 Jan 1;85(1):35-43. PMID: 22230306
Heparin: what is it? How does it work?
Schwartz BS
Clin Cardiol 1990 Apr;13(4 Suppl 6):VI12-5. PMID: 2191809
Contraception.
Lane C, Barnes AB
Prim Care 1981 Mar;8(1):45-53. PMID: 6911757
Myeloproliferative disorders.
Schwartz SI
Ann Surg 1975 Oct;182(4):464-71. doi: 10.1097/00000658-197510000-00012. PMID: 1058648Free PMC Article

Diagnosis

Clinical Review and Update on the Management of Thyroid Storm.
De Almeida R, McCalmon S, Cabandugama PK
Mo Med 2022 Jul-Aug;119(4):366-371. PMID: 36118802Free PMC Article
Managing the coagulopathy associated with cardiopulmonary bypass.
Bartoszko J, Karkouti K
J Thromb Haemost 2021 Mar;19(3):617-632. Epub 2020 Dec 17 doi: 10.1111/jth.15195. PMID: 33251719
Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding.
Wikkelsø A, Wetterslev J, Møller AM, Afshari A
Cochrane Database Syst Rev 2016 Aug 22;2016(8):CD007871. doi: 10.1002/14651858.CD007871.pub3. PMID: 27552162Free PMC Article
Excessive uterine bleeding.
Talib HJ, Coupey SM
Adolesc Med State Art Rev 2012 Apr;23(1):53-72. PMID: 22764555
Evaluation and management of abnormal uterine bleeding in premenopausal women.
Sweet MG, Schmidt-Dalton TA, Weiss PM, Madsen KP
Am Fam Physician 2012 Jan 1;85(1):35-43. PMID: 22230306

Therapy

Managing the coagulopathy associated with cardiopulmonary bypass.
Bartoszko J, Karkouti K
J Thromb Haemost 2021 Mar;19(3):617-632. Epub 2020 Dec 17 doi: 10.1111/jth.15195. PMID: 33251719
Active versus expectant management for women in the third stage of labour.
Begley CM, Gyte GM, Devane D, McGuire W, Weeks A, Biesty LM
Cochrane Database Syst Rev 2019 Feb 13;2(2):CD007412. doi: 10.1002/14651858.CD007412.pub5. PMID: 30754073Free PMC Article
Frenotomy for tongue-tie in newborn infants.
O'Shea JE, Foster JP, O'Donnell CP, Breathnach D, Jacobs SE, Todd DA, Davis PG
Cochrane Database Syst Rev 2017 Mar 11;3(3):CD011065. doi: 10.1002/14651858.CD011065.pub2. PMID: 28284020Free PMC Article
Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding.
Wikkelsø A, Wetterslev J, Møller AM, Afshari A
Cochrane Database Syst Rev 2016 Aug 22;2016(8):CD007871. doi: 10.1002/14651858.CD007871.pub3. PMID: 27552162Free PMC Article
Heparin: what is it? How does it work?
Schwartz BS
Clin Cardiol 1990 Apr;13(4 Suppl 6):VI12-5. PMID: 2191809

Prognosis

Comprehensive analysis and prediction of long-term durability of factor IX activity following etranacogene dezaparvovec gene therapy in the treatment of hemophilia B.
Shah J, Kim H, Sivamurthy K, Monahan PE, Fries M
Curr Med Res Opin 2023 Feb;39(2):227-237. Epub 2022 Oct 25 doi: 10.1080/03007995.2022.2133492. PMID: 36285399
Managing the coagulopathy associated with cardiopulmonary bypass.
Bartoszko J, Karkouti K
J Thromb Haemost 2021 Mar;19(3):617-632. Epub 2020 Dec 17 doi: 10.1111/jth.15195. PMID: 33251719
Viscoelastic testing in pediatric patients.
Haas T, Faraoni D
Transfusion 2020 Oct;60 Suppl 6:S75-S85. doi: 10.1111/trf.16076. PMID: 33089938
Inherited platelet disorders in women.
Gresele P, Falcinelli E, Bury L
Thromb Res 2019 Sep;181 Suppl 1:S54-S59. doi: 10.1016/S0049-3848(19)30368-8. PMID: 31477229
Myeloproliferative disorders.
Schwartz SI
Ann Surg 1975 Oct;182(4):464-71. doi: 10.1097/00000658-197510000-00012. PMID: 1058648Free PMC Article

Clinical prediction guides

Comprehensive analysis and prediction of long-term durability of factor IX activity following etranacogene dezaparvovec gene therapy in the treatment of hemophilia B.
Shah J, Kim H, Sivamurthy K, Monahan PE, Fries M
Curr Med Res Opin 2023 Feb;39(2):227-237. Epub 2022 Oct 25 doi: 10.1080/03007995.2022.2133492. PMID: 36285399
Managing the coagulopathy associated with cardiopulmonary bypass.
Bartoszko J, Karkouti K
J Thromb Haemost 2021 Mar;19(3):617-632. Epub 2020 Dec 17 doi: 10.1111/jth.15195. PMID: 33251719
Viscoelastic testing in pediatric patients.
Haas T, Faraoni D
Transfusion 2020 Oct;60 Suppl 6:S75-S85. doi: 10.1111/trf.16076. PMID: 33089938
Inherited platelet disorders in women.
Gresele P, Falcinelli E, Bury L
Thromb Res 2019 Sep;181 Suppl 1:S54-S59. doi: 10.1016/S0049-3848(19)30368-8. PMID: 31477229
Frenotomy for tongue-tie in newborn infants.
O'Shea JE, Foster JP, O'Donnell CP, Breathnach D, Jacobs SE, Todd DA, Davis PG
Cochrane Database Syst Rev 2017 Mar 11;3(3):CD011065. doi: 10.1002/14651858.CD011065.pub2. PMID: 28284020Free PMC Article

Recent systematic reviews

Thrombocytopenia among pregnant women in Africa: a systematic review and meta-analysis.
Getawa S, Getaneh Z, Melku M
Pan Afr Med J 2022;41:334. Epub 2022 Apr 26 doi: 10.11604/pamj.2022.41.334.30175. PMID: 35865846Free PMC Article
Progestogen-releasing intrauterine systems for heavy menstrual bleeding.
Bofill Rodriguez M, Lethaby A, Jordan V
Cochrane Database Syst Rev 2020 Jun 12;6(6):CD002126. doi: 10.1002/14651858.CD002126.pub4. PMID: 32529637Free PMC Article
Active versus expectant management for women in the third stage of labour.
Begley CM, Gyte GM, Devane D, McGuire W, Weeks A, Biesty LM
Cochrane Database Syst Rev 2019 Feb 13;2(2):CD007412. doi: 10.1002/14651858.CD007412.pub5. PMID: 30754073Free PMC Article
Frenotomy for tongue-tie in newborn infants.
O'Shea JE, Foster JP, O'Donnell CP, Breathnach D, Jacobs SE, Todd DA, Davis PG
Cochrane Database Syst Rev 2017 Mar 11;3(3):CD011065. doi: 10.1002/14651858.CD011065.pub2. PMID: 28284020Free PMC Article
Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding.
Wikkelsø A, Wetterslev J, Møller AM, Afshari A
Cochrane Database Syst Rev 2016 Aug 22;2016(8):CD007871. doi: 10.1002/14651858.CD007871.pub3. PMID: 27552162Free PMC Article

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