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Decreased red blood cell count

MedGen UID:
605665
•Concept ID:
C0427457
•
Finding
Synonyms: Decreased RBC count; RBC count low; Red blood cell count below reference range; Red blood cell count low
SNOMED CT: RBC count low (165423001); Red blood cell count low (165423001); Red blood cell count below reference range (165423001)
 
HPO: HP:0020060

Definition

An abnormal reduction below the normal number of red blood cells per volume in the circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased red blood cell count

Professional guidelines

PubMed

Hemolytic Anemia: Evaluation and Differential Diagnosis.
Phillips J, Henderson AC
Am Fam Physician 2018 Sep 15;98(6):354-361. PMID: 30215915
Hereditary Spherocytosis - Diagnosis, Surgical Treatment and Outcomes. A Literature Review.
Manciu S, Matei E, Trandafir B
Chirurgia (Bucur) 2017 Mar-Apr;112(2):110-116. doi: 10.21614/chirurgia.112.2.110. PMID: 28463670
Laboratory diagnosis of anemia: are the old and new red cell parameters useful in classification and treatment, how?
Buttarello M
Int J Lab Hematol 2016 May;38 Suppl 1:123-32. Epub 2016 May 16 doi: 10.1111/ijlh.12500. PMID: 27195903

Recent clinical studies

Etiology

Identifying key predictors of mortality in young patients on chronic haemodialysis-a machine learning approach.
Gotta V, Tancev G, Marsenic O, Vogt JE, Pfister M
Nephrol Dial Transplant 2021 Feb 20;36(3):519-528. doi: 10.1093/ndt/gfaa128. PMID: 32510143
Association of classical markers and establishment of the dyslipidemic sub-phenotype of sickle cell anemia.
Aleluia MM, da Guarda CC, Santiago RP, Fonseca TC, Neves FI, de Souza RQ, Farias LA, Pimenta FA, Fiuza LM, Pitanga TN, Ferreira JR, Adorno EV, Cerqueira BA, Gonçalves MS
Lipids Health Dis 2017 Apr 11;16(1):74. doi: 10.1186/s12944-017-0454-1. PMID: 28399852Free PMC Article

Diagnosis

Changes in the Liver Function and Hematological Parameters in Dengue Patients at a Tertiary Care Center: A Descriptive Cross-sectional Study.
Pokharel A, Pokhrel B, Bhattarai R, Khanal M
JNMA J Nepal Med Assoc 2024 May 31;62(274):382-386. doi: 10.31729/jnma.8616. PMID: 39356862Free PMC Article
Osteolytic mandible presenting as an initial manifestation of an adult acute lymphoblastic leukaemia.
Chung SW, Kim S, Choi JR, Yoo TH, Cha IH
Int J Oral Maxillofac Surg 2011 Dec;40(12):1438-40. Epub 2011 Jul 1 doi: 10.1016/j.ijom.2011.01.013. PMID: 21723711
Successful therapy of pure red cell aplasia secondary to plasma cell dyscrasia with bolus methylprednisolone.
Matsuhashi Y, Tasaka T, Uehara E, Kamei T, Tamura T, Nagai M
Intern Med 2001 Aug;40(8):802-4. doi: 10.2169/internalmedicine.40.802. PMID: 11518129
Ruptured pancreaticoduodenal arterial aneurysms: diagnosis and treatment by angiographic intervention.
Moore-Stovall J
J Natl Med Assoc 1995 Feb;87(2):149-51. PMID: 7897688Free PMC Article

Therapy

Identifying key predictors of mortality in young patients on chronic haemodialysis-a machine learning approach.
Gotta V, Tancev G, Marsenic O, Vogt JE, Pfister M
Nephrol Dial Transplant 2021 Feb 20;36(3):519-528. doi: 10.1093/ndt/gfaa128. PMID: 32510143
Efficacy and safety of darusentan: a novel endothelin receptor antagonist.
Epstein BJ
Ann Pharmacother 2008 Jul;42(7):1060-9. Epub 2008 Jun 3 doi: 10.1345/aph.1L024. PMID: 18523233
Successful therapy of pure red cell aplasia secondary to plasma cell dyscrasia with bolus methylprednisolone.
Matsuhashi Y, Tasaka T, Uehara E, Kamei T, Tamura T, Nagai M
Intern Med 2001 Aug;40(8):802-4. doi: 10.2169/internalmedicine.40.802. PMID: 11518129
Overview of the acute, subchronic, reproductive, developmental and genetic toxicology of beta-chloroprene.
Valentine R, Himmelstein MW
Chem Biol Interact 2001 Jun 1;135-136:81-100. doi: 10.1016/s0009-2797(01)00218-6. PMID: 11397383

Prognosis

Changes in the Liver Function and Hematological Parameters in Dengue Patients at a Tertiary Care Center: A Descriptive Cross-sectional Study.
Pokharel A, Pokhrel B, Bhattarai R, Khanal M
JNMA J Nepal Med Assoc 2024 May 31;62(274):382-386. doi: 10.31729/jnma.8616. PMID: 39356862Free PMC Article
Identifying key predictors of mortality in young patients on chronic haemodialysis-a machine learning approach.
Gotta V, Tancev G, Marsenic O, Vogt JE, Pfister M
Nephrol Dial Transplant 2021 Feb 20;36(3):519-528. doi: 10.1093/ndt/gfaa128. PMID: 32510143
Osteolytic mandible presenting as an initial manifestation of an adult acute lymphoblastic leukaemia.
Chung SW, Kim S, Choi JR, Yoo TH, Cha IH
Int J Oral Maxillofac Surg 2011 Dec;40(12):1438-40. Epub 2011 Jul 1 doi: 10.1016/j.ijom.2011.01.013. PMID: 21723711

Clinical prediction guides

Changes in the Liver Function and Hematological Parameters in Dengue Patients at a Tertiary Care Center: A Descriptive Cross-sectional Study.
Pokharel A, Pokhrel B, Bhattarai R, Khanal M
JNMA J Nepal Med Assoc 2024 May 31;62(274):382-386. doi: 10.31729/jnma.8616. PMID: 39356862Free PMC Article
Identifying key predictors of mortality in young patients on chronic haemodialysis-a machine learning approach.
Gotta V, Tancev G, Marsenic O, Vogt JE, Pfister M
Nephrol Dial Transplant 2021 Feb 20;36(3):519-528. doi: 10.1093/ndt/gfaa128. PMID: 32510143
Association of classical markers and establishment of the dyslipidemic sub-phenotype of sickle cell anemia.
Aleluia MM, da Guarda CC, Santiago RP, Fonseca TC, Neves FI, de Souza RQ, Farias LA, Pimenta FA, Fiuza LM, Pitanga TN, Ferreira JR, Adorno EV, Cerqueira BA, Gonçalves MS
Lipids Health Dis 2017 Apr 11;16(1):74. doi: 10.1186/s12944-017-0454-1. PMID: 28399852Free PMC Article
Successful therapy of pure red cell aplasia secondary to plasma cell dyscrasia with bolus methylprednisolone.
Matsuhashi Y, Tasaka T, Uehara E, Kamei T, Tamura T, Nagai M
Intern Med 2001 Aug;40(8):802-4. doi: 10.2169/internalmedicine.40.802. PMID: 11518129
Overview of the acute, subchronic, reproductive, developmental and genetic toxicology of beta-chloroprene.
Valentine R, Himmelstein MW
Chem Biol Interact 2001 Jun 1;135-136:81-100. doi: 10.1016/s0009-2797(01)00218-6. PMID: 11397383

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