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Aplasia of the lower vagina

MedGen UID:
609076
Concept ID:
C0431646
Congenital Abnormality
Synonyms: Absent lower vagina; Agenesis of lower vagina; Agenesis of the lower vagina
SNOMED CT: Agenesis of lower vagina (253834007)
 
HPO: HP:0012674

Definition

A failure to develop of the lower part of the vagina. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Zhang Y, Liu Q
J Obstet Gynaecol 2022 Nov;42(8):3731-3736. doi: 10.1080/01443615.2022.2158313. PMID: 37017373
Dietrich JE
J Pediatr Adolesc Gynecol 2022 Oct;35(5):536-540. Epub 2022 Apr 27 doi: 10.1016/j.jpag.2022.04.007. PMID: 35489471
Crosignani PG, Vegetti W
Drugs 1996 Nov;52(5):671-81. doi: 10.2165/00003495-199652050-00005. PMID: 9118817

Recent clinical studies

Etiology

Versteegh HP, Sutcliffe JR, Sloots CE, Wijnen RM, de Blaauw I
Tech Coloproctol 2015 Apr;19(4):201-7. Epub 2015 Feb 22 doi: 10.1007/s10151-015-1265-x. PMID: 25702171Free PMC Article
Callens N, De Cuypere G, De Sutter P, Monstrey S, Weyers S, Hoebeke P, Cools M
Hum Reprod Update 2014 Sep-Oct;20(5):775-801. Epub 2014 Jun 3 doi: 10.1093/humupd/dmu024. PMID: 24899229
Crosignani PG, Vegetti W
Drugs 1996 Nov;52(5):671-81. doi: 10.2165/00003495-199652050-00005. PMID: 9118817
Woodhouse CR
J Urol 1994 Aug;152(2 Pt 2):645-51. doi: 10.1016/s0022-5347(17)32673-3. PMID: 8021989
Mansfield MJ, Emans SJ
J Reprod Med 1984 Jun;29(6):399-410. PMID: 6379175

Diagnosis

Kvam JM, Nybo ML, Torz L, Sustarsic RK, Jensen KHR, Nielsen JE, Frederiksen H, Gadgaard S, Spiess K, Poulsen SS, Thomsen JS, Cowin P, Blomberg Jensen M, Kurita T, Rosenkilde MM
BMC Biol 2024 Apr 8;22(1):77. doi: 10.1186/s12915-024-01873-6. PMID: 38589878Free PMC Article
Zhang Y, Liu Q
J Obstet Gynaecol 2022 Nov;42(8):3731-3736. doi: 10.1080/01443615.2022.2158313. PMID: 37017373
Dietrich JE
J Pediatr Adolesc Gynecol 2022 Oct;35(5):536-540. Epub 2022 Apr 27 doi: 10.1016/j.jpag.2022.04.007. PMID: 35489471
Dietrich JE, Millar DM, Quint EH
J Pediatr Adolesc Gynecol 2014 Dec;27(6):396-402. Epub 2014 Sep 11 doi: 10.1016/j.jpag.2014.09.001. PMID: 25438708
Mansfield MJ, Emans SJ
J Reprod Med 1984 Jun;29(6):399-410. PMID: 6379175

Therapy

Pagar R, Deshkar S, Mahore J, Patole V, Deshpande H, Gandham N, Mirza S, Junnarkar M, Nawani N
Microbiol Res 2024 Sep;286:127787. Epub 2024 May 31 doi: 10.1016/j.micres.2024.127787. PMID: 38851010
HadaviBavili P, İlçioğlu K, Hamlacı Başkaya Y
J Minim Invasive Gynecol 2023 Sep;30(9):705-715. Epub 2023 Jun 2 doi: 10.1016/j.jmig.2023.05.014. PMID: 37271411
Versteegh HP, Sutcliffe JR, Sloots CE, Wijnen RM, de Blaauw I
Tech Coloproctol 2015 Apr;19(4):201-7. Epub 2015 Feb 22 doi: 10.1007/s10151-015-1265-x. PMID: 25702171Free PMC Article
Noller KL
Obstet Gynecol Clin North Am 1993 Mar;20(1):165-76. PMID: 8332308
Mansfield MJ, Emans SJ
J Reprod Med 1984 Jun;29(6):399-410. PMID: 6379175

Prognosis

Johannesson L, Humphries LA, Porrett PM, Testa G, Anderson S, Walter JR, Rush M, Ferrando CA, O'Neill K, Richards EG
Fertil Steril 2024 Sep;122(3):525-534. Epub 2024 Apr 16 doi: 10.1016/j.fertnstert.2024.04.019. PMID: 38636770
Kvam JM, Nybo ML, Torz L, Sustarsic RK, Jensen KHR, Nielsen JE, Frederiksen H, Gadgaard S, Spiess K, Poulsen SS, Thomsen JS, Cowin P, Blomberg Jensen M, Kurita T, Rosenkilde MM
BMC Biol 2024 Apr 8;22(1):77. doi: 10.1186/s12915-024-01873-6. PMID: 38589878Free PMC Article
Wang K, Yang L, Peng C, Pang W, Wang Z, Zhang D, Wu D, Chen Y
Pediatr Surg Int 2022 Sep;38(9):1283-1289. Epub 2022 Jul 3 doi: 10.1007/s00383-022-05159-2. PMID: 35780394
Ghosh S, Pattanshetty SM, Mallya SD, Pandey D, Guddattu V, Kamath VG, Kabekkodu SP, Satyamoorthy K, Shetty RS
PLoS One 2021;16(3):e0248963. Epub 2021 Mar 19 doi: 10.1371/journal.pone.0248963. PMID: 33740008Free PMC Article
Siegelman ES, Outwater EK, Banner MP, Ramchandani P, Anderson TL, Schnall MD
Radiographics 1997 Sep-Oct;17(5):1183-203. doi: 10.1148/radiographics.17.5.9308110. PMID: 9308110

Clinical prediction guides

Qi J, Zhou P, Peng H, Deng J, Shao Y, Ye L, Luo S
Reprod Sci 2024 Nov;31(11):3343-3350. Epub 2024 Jun 21 doi: 10.1007/s43032-024-01628-2. PMID: 38907127Free PMC Article
Kvam JM, Nybo ML, Torz L, Sustarsic RK, Jensen KHR, Nielsen JE, Frederiksen H, Gadgaard S, Spiess K, Poulsen SS, Thomsen JS, Cowin P, Blomberg Jensen M, Kurita T, Rosenkilde MM
BMC Biol 2024 Apr 8;22(1):77. doi: 10.1186/s12915-024-01873-6. PMID: 38589878Free PMC Article
HadaviBavili P, İlçioğlu K, Hamlacı Başkaya Y
J Minim Invasive Gynecol 2023 Sep;30(9):705-715. Epub 2023 Jun 2 doi: 10.1016/j.jmig.2023.05.014. PMID: 37271411
Wu M, Dai H, Li Q, Wang Y, Xu M, Hao Q, Xu X, Zhong X, Fang S, Sun M, Xu J, Xue C
J Plast Reconstr Aesthet Surg 2022 Jun;75(6):1964-1970. Epub 2022 Jan 22 doi: 10.1016/j.bjps.2022.01.019. PMID: 35140041
Versteegh HP, Sutcliffe JR, Sloots CE, Wijnen RM, de Blaauw I
Tech Coloproctol 2015 Apr;19(4):201-7. Epub 2015 Feb 22 doi: 10.1007/s10151-015-1265-x. PMID: 25702171Free PMC Article

Recent systematic reviews

HadaviBavili P, İlçioğlu K, Hamlacı Başkaya Y
J Minim Invasive Gynecol 2023 Sep;30(9):705-715. Epub 2023 Jun 2 doi: 10.1016/j.jmig.2023.05.014. PMID: 37271411
Stier EA, Sebring MC, Mendez AE, Ba FS, Trimble DD, Chiao EY
Am J Obstet Gynecol 2015 Sep;213(3):278-309. Epub 2015 Mar 19 doi: 10.1016/j.ajog.2015.03.034. PMID: 25797230Free PMC Article
Versteegh HP, Sutcliffe JR, Sloots CE, Wijnen RM, de Blaauw I
Tech Coloproctol 2015 Apr;19(4):201-7. Epub 2015 Feb 22 doi: 10.1007/s10151-015-1265-x. PMID: 25702171Free PMC Article
Hofmeester MJ, Draaisma JM, Versteegh HP, Huibregtse EC, van Rooij IA, de Blaauw I
Eur J Pediatr Surg 2015 Oct;25(5):389-96. Epub 2015 Feb 5 doi: 10.1055/s-0034-1544052. PMID: 25654619
Dietrich JE, Millar DM, Quint EH
J Pediatr Adolesc Gynecol 2014 Dec;27(6):396-402. Epub 2014 Sep 11 doi: 10.1016/j.jpag.2014.09.001. PMID: 25438708

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