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Cemento-Osseous Dysplasia

MedGen UID:
630147
Concept ID:
C0457523
Pathologic Function
Synonyms: Cemental Dysplasia; Cemento-osseous dysplasia; Cementoma; Osseous Dysplasia
SNOMED CT: Cemento-osseous dysplasia (278389000)

Definition

A non-neoplastic fibro-osseous lesion of the tooth-bearing regions of the gnathic bones. It is characterized by a variably cellular fibrous stroma with areas of swirling and/or loose collagen. Within the stroma are mineralizing tissues consisting of osteoid, bone, and cementum-like material. As the lesions mature, they become increasingly calcified. (WHO 2017) [from NCI]

Professional guidelines

PubMed

Park S, Jeon SJ, Yeom HG, Seo MS
BMC Oral Health 2024 Apr 11;24(1):442. doi: 10.1186/s12903-024-04208-7. PMID: 38605361Free PMC Article
Veltrini VC, Figueira JA, Santin GC, de Sousa SCOM, de Araújo NS
Pathol Res Pract 2019 Jul;215(7):152450. Epub 2019 May 13 doi: 10.1016/j.prp.2019.152450. PMID: 31109869
Slootweg PJ
Semin Diagn Pathol 1996 May;13(2):104-12. PMID: 8734416

Recent clinical studies

Etiology

Günaçar DN, Köse TE, Arıcıoğlu B, Çene E
Dent Med Probl 2023 Jul-Sep;60(3):393-400. doi: 10.17219/dmp/133405. PMID: 37796046
Bastos YVP, Carlos R, Oliveira PT, Pires BC, Cangussu MCT, Xavier FCA, Koga-Ito CY, Manieri PR, Souza AS, Júnior BC, Ramalho LMP, Cury PR, Santos JND
Ann Diagn Pathol 2022 Oct;60:152009. Epub 2022 Jul 12 doi: 10.1016/j.anndiagpath.2022.152009. PMID: 35868115
Hameed M, Horvai AE, Jordan RCK
Head Neck Pathol 2020 Mar;14(1):70-82. Epub 2020 Jan 16 doi: 10.1007/s12105-019-01094-2. PMID: 31950477Free PMC Article
Kato CN, Barra SG, Pereira MJ, Gomes LT, Amaral TM, Abreu LG, Brasileiro CB, Mesquita RA
Dentomaxillofac Radiol 2020 May 1;49(4):20190359. Epub 2019 Dec 20 doi: 10.1259/dmfr.20190359. PMID: 31846355Free PMC Article
Macdonald-Jankowski DS
Dentomaxillofac Radiol 2008 Sep;37(6):350-60. doi: 10.1259/dmfr/31641295. PMID: 18757721

Diagnosis

Günaçar DN, Köse TE, Arıcıoğlu B, Çene E
Dent Med Probl 2023 Jul-Sep;60(3):393-400. doi: 10.17219/dmp/133405. PMID: 37796046
Panta P, Shahid I, Patil S, Seshadri M
J Contemp Dent Pract 2021 Mar 1;22(3):304-309. PMID: 34210933
Kato CNAO, de Arruda JAA, Mendes PA, Neiva IM, Abreu LG, Moreno A, Silva TA, Souza LN, Mesquita RA
Head Neck Pathol 2020 Mar;14(1):173-182. Epub 2019 Apr 22 doi: 10.1007/s12105-019-01037-x. PMID: 31011984Free PMC Article
Fenerty S, Shaw W, Verma R, Syed AB, Kuklani R, Yang J, Ali S
Skeletal Radiol 2017 May;46(5):581-590. Epub 2017 Feb 13 doi: 10.1007/s00256-017-2590-0. PMID: 28194495
Harsha VB, Saraswathy K, Koteeswaran D
Indian J Dent Res 2005 Jul-Sep;16(3):119-21. PMID: 16454327

Therapy

Kato CN, Barra SG, Pereira MJ, Gomes LT, Amaral TM, Abreu LG, Brasileiro CB, Mesquita RA
Dentomaxillofac Radiol 2020 May 1;49(4):20190359. Epub 2019 Dec 20 doi: 10.1259/dmfr.20190359. PMID: 31846355Free PMC Article
Shin HS, Kim BC, Lim HJ, Jo SY, Lee J
Br J Oral Maxillofac Surg 2019 Apr;57(3):268-270. Epub 2019 Mar 18 doi: 10.1016/j.bjoms.2019.01.014. PMID: 30898454
Consolaro A, Paschoal SRB, Ponce JB, Miranda DAO
Dental Press J Orthod 2018 May-Jun;23(3):26-34. doi: 10.1590/2177-6709.23.3.026-034.oin. PMID: 30088561Free PMC Article
Mufeed A, Mangalath U, George A, Hafiz A
BMJ Case Rep 2015 Mar 9;2015 doi: 10.1136/bcr-2014-209099. PMID: 25754168Free PMC Article
Martini MZ, de Carvalho Júnior JP, Soares HA
Minerva Stomatol 2006 Sep;55(9):515-21. PMID: 17146430

Prognosis

Nemec SF, Schneider S, Friedrich KM, Weber M, Schwarz-Nemec U
J Craniomaxillofac Surg 2024 May;52(5):644-651. Epub 2024 Mar 12 doi: 10.1016/j.jcms.2024.03.008. PMID: 38582672
Haefliger S, Turek D, Andrei V, Alborelli I, Calgua B, Ameline B, Harder D, Baumhoer D
Pathology 2023 Apr;55(3):324-328. Epub 2022 Dec 21 doi: 10.1016/j.pathol.2022.10.006. PMID: 36707318
Nelson BL, Phillips BJ
Head Neck Pathol 2019 Sep;13(3):466-475. Epub 2019 Mar 18 doi: 10.1007/s12105-018-0992-5. PMID: 30887390Free PMC Article
Fenerty S, Shaw W, Verma R, Syed AB, Kuklani R, Yang J, Ali S
Skeletal Radiol 2017 May;46(5):581-590. Epub 2017 Feb 13 doi: 10.1007/s00256-017-2590-0. PMID: 28194495
Bulut EU, Acikgoz A, Ozan B, Zengin AZ, Gunhan O
J Contemp Dent Pract 2012 Jan 1;13(1):115-8. doi: 10.5005/jp-journals-10024-1105. PMID: 22430704

Clinical prediction guides

Günaçar DN, Köse TE, Arıcıoğlu B, Çene E
Dent Med Probl 2023 Jul-Sep;60(3):393-400. doi: 10.17219/dmp/133405. PMID: 37796046
Davidova LA, Bhattacharyya I, Islam MN, Cohen DM, Fitzpatrick SG
Head Neck Pathol 2020 Jun;14(2):353-361. Epub 2019 May 11 doi: 10.1007/s12105-019-01039-9. PMID: 31079311Free PMC Article
Bulut EU, Acikgoz A, Ozan B, Zengin AZ, Gunhan O
J Contemp Dent Pract 2012 Jan 1;13(1):115-8. doi: 10.5005/jp-journals-10024-1105. PMID: 22430704
Alsufyani NA, Lam EW
J Can Dent Assoc 2011;77:b70. PMID: 21683027
MacDonald-Jankowski DS
Dentomaxillofac Radiol 2003 May;32(3):141-9. doi: 10.1259/dmfr/32988764. PMID: 12917278

Recent systematic reviews

Macdonald-Jankowski DS
Dentomaxillofac Radiol 2008 Sep;37(6):350-60. doi: 10.1259/dmfr/31641295. PMID: 18757721
MacDonald-Jankowski DS
Dentomaxillofac Radiol 2003 May;32(3):141-9. doi: 10.1259/dmfr/32988764. PMID: 12917278

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