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Multiple meningiomas

MedGen UID:: 64453
•Concept ID:: C0205834
•: Neoplastic Process

Synonyms:	Meningioma, Multiple; Meningiomas, Multiple; Meningiomatoses; Meningiomatosis; Multiple Meningioma; Multiple Meningiomas
SNOMED CT:	Meningiomatosis (40935003); Diffuse meningiomatosis (40935003); Multiple meningiomas (40935003)

HPO:	HP:0033714

Definition

The occurrence of multiple distinct meningiomas in the same individual. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMultiple meningiomas

Disorder by Site
- Disorder of nervous system
  - Disorder of the central nervous system
    - Neoplasm of the central nervous system
      - Benign neoplasm of the central nervous system
        Meningioma
        Multiple meningiomas
        Multiple skull base meningioma
        Multiple spinal canal and spinal cord meningioma

Professional guidelines

PubMed

The role of mifepristone in the management of meningiomas: A systematic review of literature.

Sharma R, Garg K, Katiyar V, Tandon V, Agarwal D, Singh M, Chandra SP, Suri A, Kale SS, Mahapatra AK
Neurol India 2019 May-Jun;67(3):698-705. doi: 10.4103/0028-3886.263232. PMID: 31347538

Fertility treatment is associated with multiple meningiomas and younger age at diagnosis.

Shahin MN, Magill ST, Dalle Ore CL, Viner JA, Peters PN, Solomon DA, McDermott MW
J Neurooncol 2019 May;143(1):137-144. Epub 2019 Mar 13 doi: 10.1007/s11060-019-03147-6. PMID: 30868355 Free PMC Article

Management of pediatric intracranial meningiomas: an analysis of 31 cases and review of literature.

Ravindranath K, Vasudevan MC, Pande A, Symss N
Childs Nerv Syst 2013 Apr;29(4):573-82. Epub 2013 Jan 5 doi: 10.1007/s00381-012-2010-7. PMID: 23292441

See all (3)

Recent clinical studies

Etiology

Management of multiple meningiomas.

Tsermoulas G, Turel MK, Wilcox JT, Shultz D, Farb R, Zadeh G, Bernstein M
J Neurosurg 2018 May;128(5):1403-1409. Epub 2017 Jul 21 doi: 10.3171/2017.2.JNS162608. PMID: 28731398

Meningiomas and neurofibromatosis.

Goutagny S, Kalamarides M
J Neurooncol 2010 Sep;99(3):341-7. Epub 2010 Aug 17 doi: 10.1007/s11060-010-0339-x. PMID: 20714782

Spontaneous, multiple meningiomas.

Salvati M, Caroli E, Ferrante L, Rocchi G, D' Andrea G, Piccirilli M, Delfini R
Zentralbl Neurochir 2004 Nov;65(4):180-4. doi: 10.1055/s-2004-832349. PMID: 15551182

Recurrence of meningiomas.

Yamasaki F, Yoshioka H, Hama S, Sugiyama K, Arita K, Kurisu K
Cancer 2000 Sep 1;89(5):1102-10. doi: 10.1002/1097-0142(20000901)89:5<1102::aid-cncr20>3.0.co;2-l. PMID: 10964341

Intracranial meningioma.

Howng SL, Kwan AL
Gaoxiong Yi Xue Ke Xue Za Zhi 1992 Jun;8(6):312-9. PMID: 1404534

See all (65)

Diagnosis

Neurofibromatosis Type 2 (NF2) and the Implications for Vestibular Schwannoma and Meningioma Pathogenesis.

Bachir S, Shah S, Shapiro S, Koehler A, Mahammedi A, Samy RN, Zuccarello M, Schorry E, Sengupta S
Int J Mol Sci 2021 Jan 12;22(2) doi: 10.3390/ijms22020690. PMID: 33445724 Free PMC Article

Neurofibromatosis type 2.

Slattery WH
Otolaryngol Clin North Am 2015 Jun;48(3):443-60. doi: 10.1016/j.otc.2015.02.005. PMID: 26043141

Meningiomas and neurofibromatosis.

Goutagny S, Kalamarides M
J Neurooncol 2010 Sep;99(3):341-7. Epub 2010 Aug 17 doi: 10.1007/s11060-010-0339-x. PMID: 20714782

Meningiomas in lymphangioleiomyomatosis.

Moss J, DeCastro R, Patronas NJ, Taveira-DaSilva A
JAMA 2001 Oct 17;286(15):1879-81. doi: 10.1001/jama.286.15.1879. PMID: 11597290

Multiple meningiomas.

Andrioli GC, Rigobello L, Iob I, Casentini L
Neurochirurgia (Stuttg) 1981 Mar;24(2):67-9. doi: 10.1055/s-2008-1053846. PMID: 7219658

See all (105)

Therapy

Sporadic and neurofibromatosis type 2-associated meningioma in children and adolescents.

Wagener K, Beckhaus J, Boekhoff S, Friedrich C, Müller HL
J Neurooncol 2023 Jul;163(3):555-563. Epub 2023 Jul 4 doi: 10.1007/s11060-023-04344-0. PMID: 37402092

Fertility treatment is associated with multiple meningiomas and younger age at diagnosis.

Radiation-Induced Meningiomas: An Exhaustive Review of the Literature.

Yamanaka R, Hayano A, Kanayama T
World Neurosurg 2017 Jan;97:635-644.e8. Epub 2016 Oct 3 doi: 10.1016/j.wneu.2016.09.094. PMID: 27713063

Multiple faces of children and juvenile meningiomas: a report of single-center experience and review of literature.

Stanuszek A, Piątek P, Kwiatkowski S, Adamek D
Clin Neurol Neurosurg 2014 Mar;118:69-75. Epub 2014 Jan 7 doi: 10.1016/j.clineuro.2013.12.019. PMID: 24529233

Meningiomas in lymphangioleiomyomatosis.

Moss J, DeCastro R, Patronas NJ, Taveira-DaSilva A
JAMA 2001 Oct 17;286(15):1879-81. doi: 10.1001/jama.286.15.1879. PMID: 11597290

See all (35)

Prognosis

Management of multiple meningiomas.

Tsermoulas G, Turel MK, Wilcox JT, Shultz D, Farb R, Zadeh G, Bernstein M
J Neurosurg 2018 May;128(5):1403-1409. Epub 2017 Jul 21 doi: 10.3171/2017.2.JNS162608. PMID: 28731398

Meningiomas and neurofibromatosis.

Goutagny S, Kalamarides M
J Neurooncol 2010 Sep;99(3):341-7. Epub 2010 Aug 17 doi: 10.1007/s11060-010-0339-x. PMID: 20714782

Spontaneous, multiple meningiomas.

Salvati M, Caroli E, Ferrante L, Rocchi G, D' Andrea G, Piccirilli M, Delfini R
Zentralbl Neurochir 2004 Nov;65(4):180-4. doi: 10.1055/s-2004-832349. PMID: 15551182

Recurrence of meningiomas.

Yamasaki F, Yoshioka H, Hama S, Sugiyama K, Arita K, Kurisu K
Cancer 2000 Sep 1;89(5):1102-10. doi: 10.1002/1097-0142(20000901)89:5<1102::aid-cncr20>3.0.co;2-l. PMID: 10964341

Multiple intracranial meningiomas.

Domenicucci M, Santoro A, D'Osvaldo DH, Delfini R, Cantore GP, Guidetti B
J Neurosurg 1989 Jan;70(1):41-4. doi: 10.3171/jns.1989.70.1.0041. PMID: 2909686

See all (49)

Clinical prediction guides

Intracranial meningioma and concomitant cavernous malformation: A series description and review of the literature.

Missori P, Peschillo S, Ambrosone A, Martini S, Rastelli E, Mancarella C, Vigliotta M, Paolini S
Clin Neurol Neurosurg 2020 Oct;197:106167. Epub 2020 Aug 22 doi: 10.1016/j.clineuro.2020.106167. PMID: 32861039

Multiple Intracranial Meningiomas: A Case Series and Review of the Literature.

Araújo Pereira BJ, Nogueira de Almeida A, Pires de Aguiar PH, Paiva WS, Teixeira MJ, Nagahashi Marie SK
World Neurosurg 2019 Feb;122:e1536-e1541. Epub 2018 Nov 22 doi: 10.1016/j.wneu.2018.11.097. PMID: 30471445

Management of multiple meningiomas.

Tsermoulas G, Turel MK, Wilcox JT, Shultz D, Farb R, Zadeh G, Bernstein M
J Neurosurg 2018 May;128(5):1403-1409. Epub 2017 Jul 21 doi: 10.3171/2017.2.JNS162608. PMID: 28731398

Meningiomas in lymphangioleiomyomatosis.

Moss J, DeCastro R, Patronas NJ, Taveira-DaSilva A
JAMA 2001 Oct 17;286(15):1879-81. doi: 10.1001/jama.286.15.1879. PMID: 11597290

Recurrence of meningiomas.

Yamasaki F, Yoshioka H, Hama S, Sugiyama K, Arita K, Kurisu K
Cancer 2000 Sep 1;89(5):1102-10. doi: 10.1002/1097-0142(20000901)89:5<1102::aid-cncr20>3.0.co;2-l. PMID: 10964341

See all (40)

Recent systematic reviews

The role of mifepristone in the management of meningiomas: A systematic review of literature.

Sharma R, Garg K, Katiyar V, Tandon V, Agarwal D, Singh M, Chandra SP, Suri A, Kale SS, Mahapatra AK
Neurol India 2019 May-Jun;67(3):698-705. doi: 10.4103/0028-3886.263232. PMID: 31347538

Surgery versus stereotactic radiosurgery for the treatment of multiple meningiomas in neurofibromatosis type 2: illustrative case and systematic review.

Nguyen T, Chung LK, Sheppard JP, Bhatt NS, Chen CHJ, Lagman C, Kaprealian T, Lee P, Nghiemphu PL, Yang I
Neurosurg Rev 2019 Mar;42(1):85-96. Epub 2017 Sep 13 doi: 10.1007/s10143-017-0904-2. PMID: 28900754

See all (2)

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Multiple meningiomas

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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