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Papillary cystadenocarcinoma

MedGen UID:
64635
•Concept ID:
C0206700
•
Neoplastic Process
Synonyms: Cystadenocarcinoma, Papillary; Cystadenocarcinomas, Papillary; Papillary Cystadenocarcinoma; Papillary Cystadenocarcinomas
SNOMED CT: Papillary cystadenocarcinoma (2735009); Papillocystic adenocarcinoma (2735009)
 
Monarch Initiative: MONDO:0005074

Definition

A malignant cystic serous or mucinous epithelial neoplasm characterized by the presence of malignant glandular epithelial cells forming papillary structures. Stromal invasion is present. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPapillary cystadenocarcinoma

Professional guidelines

PubMed

Hepatic Cysts: Reappraisal of the Classification, Terminology, Differential Diagnosis, and Clinicopathologic Characteristics in 258 Cases.
Armutlu A, Quigley B, Choi H, Basturk O, Akkas G, Pehlivanoglu B, Memis B, Jang KT, Erkan M, Erkan B, Balci S, Saka B, Bagci P, Farris AB, Kooby DA, Martin D, Kalb B, Maithel SK, Sarmiento J, Reid MD, Adsay NV
Am J Surg Pathol 2022 Sep 1;46(9):1219-1233. Epub 2022 Jul 4 doi: 10.1097/PAS.0000000000001930. PMID: 35778790
Diagnosis and Management of Pancreatic Cystic Neoplasms.
Kim TS, Fernandez-del Castillo C
Hematol Oncol Clin North Am 2015 Aug;29(4):655-74. Epub 2015 Jun 6 doi: 10.1016/j.hoc.2015.04.002. PMID: 26226903
Cystic and ductal tumors of the pancreas: diagnosis and management.
Scoazec JY, Vullierme MP, Barthet M, Gonzalez JM, Sauvanet A
J Visc Surg 2013 Apr;150(2):69-84. Epub 2013 Mar 19 doi: 10.1016/j.jviscsurg.2013.02.003. PMID: 23518192

Recent clinical studies

Etiology

Low-grade serous ovarian cancer: expert consensus report on the state of the science.
Grisham RN, Slomovitz BM, Andrews N, Banerjee S, Brown J, Carey MS, Chui H, Coleman RL, Fader AN, Gaillard S, Gourley C, Sood AK, Monk BJ, Moore KN, Ray-Coquard I, Shih IM, Westin SN, Wong KK, Gershenson DM
Int J Gynecol Cancer 2023 Sep 4;33(9):1331-1344. doi: 10.1136/ijgc-2023-004610. PMID: 37591609Free PMC Article
Papillary Neoplasms of the Salivary Duct System: A Review.
Agaimy A
Surg Pathol Clin 2021 Mar;14(1):53-65. Epub 2020 Dec 15 doi: 10.1016/j.path.2020.09.007. PMID: 33526223
Analysis of clinical and pathological characteristics, treatment methods, survival, and prognosis of uterine papillary serous carcinoma.
Solmaz U, Ekin A, Mat E, Gezer C, Dogan A, Biler A, Peker N, Hasdemir PS, Sanci M
Tumori 2016 Dec 1;102(6):593-599. Epub 2016 Aug 4 doi: 10.5301/tj.5000531. PMID: 27514313
Clear-cell and papillary serous cancer: treatment options.
Tropé C, Kristensen GB, Abeler VM
Best Pract Res Clin Obstet Gynaecol 2001 Jun;15(3):433-46. doi: 10.1053/beog.2000.0187. PMID: 11476564
Observations on the etiology and pathogenesis of intraductal papillary-mucinous neoplasms of the pancreas.
Longnecker DS
Hepatogastroenterology 1998 Nov-Dec;45(24):1973-80. PMID: 9951850

Diagnosis

Low-grade serous ovarian cancer: expert consensus report on the state of the science.
Grisham RN, Slomovitz BM, Andrews N, Banerjee S, Brown J, Carey MS, Chui H, Coleman RL, Fader AN, Gaillard S, Gourley C, Sood AK, Monk BJ, Moore KN, Ray-Coquard I, Shih IM, Westin SN, Wong KK, Gershenson DM
Int J Gynecol Cancer 2023 Sep 4;33(9):1331-1344. doi: 10.1136/ijgc-2023-004610. PMID: 37591609Free PMC Article
Novel therapeutics in low-grade serous ovarian cancer.
Cobb L, Gershenson D
Int J Gynecol Cancer 2023 Mar 6;33(3):377-384. doi: 10.1136/ijgc-2022-003677. PMID: 36878564
Papillary Neoplasms of the Salivary Duct System: A Review.
Agaimy A
Surg Pathol Clin 2021 Mar;14(1):53-65. Epub 2020 Dec 15 doi: 10.1016/j.path.2020.09.007. PMID: 33526223
Cystadenocarcinoma of the mandible.
Madathil J, Kumar NR, Shiny P
Indian J Dent Res 2018 May-Jun;29(3):396-399. doi: 10.4103/ijdr.IJDR_768_16. PMID: 29900928
Cystic neoplasms of the pancreas; what a clinician should know.
Sakorafas GH, Sarr MG
Cancer Treat Rev 2005 Nov;31(7):507-35. Epub 2005 Oct 26 doi: 10.1016/j.ctrv.2005.09.001. PMID: 16257126

Therapy

Low-grade serous ovarian cancer: expert consensus report on the state of the science.
Grisham RN, Slomovitz BM, Andrews N, Banerjee S, Brown J, Carey MS, Chui H, Coleman RL, Fader AN, Gaillard S, Gourley C, Sood AK, Monk BJ, Moore KN, Ray-Coquard I, Shih IM, Westin SN, Wong KK, Gershenson DM
Int J Gynecol Cancer 2023 Sep 4;33(9):1331-1344. doi: 10.1136/ijgc-2023-004610. PMID: 37591609Free PMC Article
Uterine papillary serous carcinoma: epidemiology, pathogenesis and management.
Fader AN, Boruta D, Olawaiye AB, Gehrig PA
Curr Opin Obstet Gynecol 2010 Feb;22(1):21-9. doi: 10.1097/GCO.0b013e328334d8a3. PMID: 19952744
Uterine papillary serous carcinoma: state of the state.
Naumann RW
Curr Oncol Rep 2008 Nov;10(6):505-11. doi: 10.1007/s11912-008-0076-x. PMID: 18928665
Old and new perspectives in the pharmacological treatment of advanced or recurrent endometrial cancer: Hormonal therapy, chemotherapy and molecularly targeted therapies.
Gadducci A, Cosio S, Genazzani AR
Crit Rev Oncol Hematol 2006 Jun;58(3):242-56. Epub 2006 Jan 24 doi: 10.1016/j.critrevonc.2005.11.002. PMID: 16436330
Clear-cell and papillary serous cancer: treatment options.
Tropé C, Kristensen GB, Abeler VM
Best Pract Res Clin Obstet Gynaecol 2001 Jun;15(3):433-46. doi: 10.1053/beog.2000.0187. PMID: 11476564

Prognosis

Papillary Neoplasms of the Salivary Duct System: A Review.
Agaimy A
Surg Pathol Clin 2021 Mar;14(1):53-65. Epub 2020 Dec 15 doi: 10.1016/j.path.2020.09.007. PMID: 33526223
Cystadenocarcinoma of the mandible.
Madathil J, Kumar NR, Shiny P
Indian J Dent Res 2018 May-Jun;29(3):396-399. doi: 10.4103/ijdr.IJDR_768_16. PMID: 29900928
Analysis of clinical and pathological characteristics, treatment methods, survival, and prognosis of uterine papillary serous carcinoma.
Solmaz U, Ekin A, Mat E, Gezer C, Dogan A, Biler A, Peker N, Hasdemir PS, Sanci M
Tumori 2016 Dec 1;102(6):593-599. Epub 2016 Aug 4 doi: 10.5301/tj.5000531. PMID: 27514313
Cystic neoplasms of the pancreas; what a clinician should know.
Sakorafas GH, Sarr MG
Cancer Treat Rev 2005 Nov;31(7):507-35. Epub 2005 Oct 26 doi: 10.1016/j.ctrv.2005.09.001. PMID: 16257126
Clear-cell and papillary serous cancer: treatment options.
Tropé C, Kristensen GB, Abeler VM
Best Pract Res Clin Obstet Gynaecol 2001 Jun;15(3):433-46. doi: 10.1053/beog.2000.0187. PMID: 11476564

Clinical prediction guides

Whole exome sequencing of low grade serous ovarian carcinoma identifies genomic events associated with clinical outcome.
Thomson JP, Hollis RL, van Baal J, Ilenkovan N, Churchman M, van de Vijver K, Dijk F, Meynert AM, Bartos C, Rye T, Croy I, Diana P, van Gent M, Creedon H, Nirsimloo R, Nussey F, Lok C, Herrington CS, Gourley C
Gynecol Oncol 2023 Jul;174:157-166. Epub 2023 May 17 doi: 10.1016/j.ygyno.2023.04.011. PMID: 37207500
Clinical calculator predictive of chemotherapy benefit in stage 1A uterine papillary serous cancers.
Mysona DP, Tran LKH, Tran PMH, Gehrig PA, Van Le L, Ghamande S, Rungruang BJ, Java J, Mann AK, Liao J, Kapp DS, Santos BD, She JX, Chan JK
Gynecol Oncol 2020 Jan;156(1):77-84. Epub 2019 Nov 30 doi: 10.1016/j.ygyno.2019.10.017. PMID: 31796203
Uterine papillary serous carcinoma: epidemiology, pathogenesis and management.
Fader AN, Boruta D, Olawaiye AB, Gehrig PA
Curr Opin Obstet Gynecol 2010 Feb;22(1):21-9. doi: 10.1097/GCO.0b013e328334d8a3. PMID: 19952744
Peritoneal serous papillary carcinoma: a reappraisal of CT imaging features and literature review.
Chiou SY, Sheu MH, Wang JH, Chang CY
Abdom Imaging 2003 Nov-Dec;28(6):815-9. doi: 10.1007/s00261-003-0038-6. PMID: 14753596
Observations on the etiology and pathogenesis of intraductal papillary-mucinous neoplasms of the pancreas.
Longnecker DS
Hepatogastroenterology 1998 Nov-Dec;45(24):1973-80. PMID: 9951850

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