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Neuroendocrine neoplasm

MedGen UID:
64652
Concept ID:
C0206754
Neoplastic Process
Synonyms: Neuroendocrine Tumor; Neuroendocrine Tumors; Tumor, Neuroendocrine; Tumors, Neuroendocrine
SNOMED CT: Neuroendocrine neoplasm (128928004); Neuroendocrine tumor (55937004); Neuroendocrine tumor (255046005)
Modes of inheritance:
Unknown inheritance
MedGen UID:
989040
Concept ID:
CN307042
Finding
Source: Orphanet
Hereditary clinical entity whose mode of inheritance is unknown.
 
HPO: HP:0100634
Monarch Initiative: MONDO:0019496
Orphanet: ORPHA877

Definition

A tumor that originates from a neuroendocrine cell. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeuroendocrine neoplasm

Professional guidelines

PubMed

Rossi RE, Elvevi A, Citterio D, Coppa J, Invernizzi P, Mazzaferro V, Massironi S
World J Gastroenterol 2021 Sep 21;27(35):5890-5907. doi: 10.3748/wjg.v27.i35.5890. PMID: 34629807Free PMC Article
Ito T, Masui T, Komoto I, Doi R, Osamura RY, Sakurai A, Ikeda M, Takano K, Igarashi H, Shimatsu A, Nakamura K, Nakamoto Y, Hijioka S, Morita K, Ishikawa Y, Ohike N, Kasajima A, Kushima R, Kojima M, Sasano H, Hirano S, Mizuno N, Aoki T, Aoki T, Ohtsuka T, Okumura T, Kimura Y, Kudo A, Konishi T, Matsumoto I, Kobayashi N, Fujimori N, Honma Y, Morizane C, Uchino S, Horiuchi K, Yamasaki M, Matsubayashi J, Sato Y, Sekiguchi M, Abe S, Okusaka T, Kida M, Kimura W, Tanaka M, Majima Y, Jensen RT, Hirata K, Imamura M, Uemoto S
J Gastroenterol 2021 Nov;56(11):1033-1044. Epub 2021 Sep 29 doi: 10.1007/s00535-021-01827-7. PMID: 34586495Free PMC Article
Ito T, Jensen RT
Expert Opin Pharmacother 2021 Apr;22(6):685-693. Epub 2020 Nov 11 doi: 10.1080/14656566.2020.1845651. PMID: 33131345Free PMC Article

Recent clinical studies

Etiology

Brown IS, Sokolova A, Rosty C, Graham RP
Histopathology 2023 Jan;82(2):232-241. Epub 2022 Aug 24 doi: 10.1111/his.14769. PMID: 35962741
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Rossi RE, Elvevi A, Citterio D, Coppa J, Invernizzi P, Mazzaferro V, Massironi S
World J Gastroenterol 2021 Sep 21;27(35):5890-5907. doi: 10.3748/wjg.v27.i35.5890. PMID: 34629807Free PMC Article
Patel SP, Mayerson E, Chae YK, Strosberg J, Wang J, Konda B, Hayward J, McLeod CM, Chen HX, Sharon E, Othus M, Ryan CW, Plets M, Blanke CD, Kurzrock R
Cancer 2021 Sep 1;127(17):3194-3201. Epub 2021 Apr 21 doi: 10.1002/cncr.33591. PMID: 33882143Free PMC Article
Van de Moortele M, De Hertogh G, Sagaert X, Van Cutsem E
Acta Gastroenterol Belg 2020 Jul-Sep;83(3):441-448. PMID: 33094592

Diagnosis

Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Nicholson AG, Tsao MS, Beasley MB, Borczuk AC, Brambilla E, Cooper WA, Dacic S, Jain D, Kerr KM, Lantuejoul S, Noguchi M, Papotti M, Rekhtman N, Scagliotti G, van Schil P, Sholl L, Yatabe Y, Yoshida A, Travis WD
J Thorac Oncol 2022 Mar;17(3):362-387. Epub 2021 Nov 20 doi: 10.1016/j.jtho.2021.11.003. PMID: 34808341
Rekhtman N
Mod Pathol 2022 Jan;35(Suppl 1):36-50. Epub 2021 Oct 18 doi: 10.1038/s41379-021-00943-2. PMID: 34663914Free PMC Article
Ito T, Masui T, Komoto I, Doi R, Osamura RY, Sakurai A, Ikeda M, Takano K, Igarashi H, Shimatsu A, Nakamura K, Nakamoto Y, Hijioka S, Morita K, Ishikawa Y, Ohike N, Kasajima A, Kushima R, Kojima M, Sasano H, Hirano S, Mizuno N, Aoki T, Aoki T, Ohtsuka T, Okumura T, Kimura Y, Kudo A, Konishi T, Matsumoto I, Kobayashi N, Fujimori N, Honma Y, Morizane C, Uchino S, Horiuchi K, Yamasaki M, Matsubayashi J, Sato Y, Sekiguchi M, Abe S, Okusaka T, Kida M, Kimura W, Tanaka M, Majima Y, Jensen RT, Hirata K, Imamura M, Uemoto S
J Gastroenterol 2021 Nov;56(11):1033-1044. Epub 2021 Sep 29 doi: 10.1007/s00535-021-01827-7. PMID: 34586495Free PMC Article
Clift AK, Kidd M, Bodei L, Toumpanakis C, Baum RP, Oberg K, Modlin IM, Frilling A
Neuroendocrinology 2020;110(6):444-476. Epub 2019 Sep 27 doi: 10.1159/000503721. PMID: 31557758Free PMC Article

Therapy

Pan WX, Zhang XM, Hao SL, Han W
World J Gastroenterol 2023 Jul 14;29(26):4174-4185. doi: 10.3748/wjg.v29.i26.4174. PMID: 37475845Free PMC Article
Garcia-Carbonero R, Anton-Pascual B, Modrego A, Del Carmen Riesco-Martinez M, Lens-Pardo A, Carretero-Puche C, Rubio-Cuesta B, Soldevilla B
Endocr Rev 2023 Jul 11;44(4):724-736. doi: 10.1210/endrev/bnad006. PMID: 36879384Free PMC Article
Patel SP, Mayerson E, Chae YK, Strosberg J, Wang J, Konda B, Hayward J, McLeod CM, Chen HX, Sharon E, Othus M, Ryan CW, Plets M, Blanke CD, Kurzrock R
Cancer 2021 Sep 1;127(17):3194-3201. Epub 2021 Apr 21 doi: 10.1002/cncr.33591. PMID: 33882143Free PMC Article
Van de Moortele M, De Hertogh G, Sagaert X, Van Cutsem E
Acta Gastroenterol Belg 2020 Jul-Sep;83(3):441-448. PMID: 33094592
Patel SP, Othus M, Chae YK, Giles FJ, Hansel DE, Singh PP, Fontaine A, Shah MH, Kasi A, Baghdadi TA, Matrana M, Gatalica Z, Korn WM, Hayward J, McLeod C, Chen HX, Sharon E, Mayerson E, Ryan CW, Plets M, Blanke CD, Kurzrock R
Clin Cancer Res 2020 May 15;26(10):2290-2296. Epub 2020 Jan 22 doi: 10.1158/1078-0432.CCR-19-3356. PMID: 31969335Free PMC Article

Prognosis

Nicholson AG, Tsao MS, Beasley MB, Borczuk AC, Brambilla E, Cooper WA, Dacic S, Jain D, Kerr KM, Lantuejoul S, Noguchi M, Papotti M, Rekhtman N, Scagliotti G, van Schil P, Sholl L, Yatabe Y, Yoshida A, Travis WD
J Thorac Oncol 2022 Mar;17(3):362-387. Epub 2021 Nov 20 doi: 10.1016/j.jtho.2021.11.003. PMID: 34808341
Rekhtman N
Mod Pathol 2022 Jan;35(Suppl 1):36-50. Epub 2021 Oct 18 doi: 10.1038/s41379-021-00943-2. PMID: 34663914Free PMC Article
Van de Moortele M, De Hertogh G, Sagaert X, Van Cutsem E
Acta Gastroenterol Belg 2020 Jul-Sep;83(3):441-448. PMID: 33094592
Hrabe J
Surg Oncol Clin N Am 2020 Apr;29(2):267-279. doi: 10.1016/j.soc.2019.11.010. PMID: 32151360
Clift AK, Kidd M, Bodei L, Toumpanakis C, Baum RP, Oberg K, Modlin IM, Frilling A
Neuroendocrinology 2020;110(6):444-476. Epub 2019 Sep 27 doi: 10.1159/000503721. PMID: 31557758Free PMC Article

Clinical prediction guides

Uccella S
Endocr Pathol 2024 Jun;35(2):91-106. Epub 2024 Mar 12 doi: 10.1007/s12022-024-09807-2. PMID: 38470548
Rekhtman N
Mod Pathol 2022 Jan;35(Suppl 1):36-50. Epub 2021 Oct 18 doi: 10.1038/s41379-021-00943-2. PMID: 34663914Free PMC Article
Metovic J, Barella M, Harari S, Pattini L, Albini A, Sonzogni A, Veronesi G, Papotti M, Pelosi G
Expert Rev Anticancer Ther 2021 Apr;21(4):377-387. Epub 2020 Dec 24 doi: 10.1080/14737140.2021.1862654. PMID: 33306420
Rindi G, Inzani F
Endocr Relat Cancer 2020 Jun;27(6):R211-R218. doi: 10.1530/ERC-20-0036. PMID: 32276263
Clift AK, Kidd M, Bodei L, Toumpanakis C, Baum RP, Oberg K, Modlin IM, Frilling A
Neuroendocrinology 2020;110(6):444-476. Epub 2019 Sep 27 doi: 10.1159/000503721. PMID: 31557758Free PMC Article

Recent systematic reviews

Paisey SA, Weerasuriya S, Palmer K, White BE, Srirajaskanthan R, Chandrakumaran K, Ramage JK
J Neuroendocrinol 2022 Dec;34(12):e13215. Epub 2022 Dec 16 doi: 10.1111/jne.13215. PMID: 36524462
Schuch LF, Schmidt TR, de Oliveira Zigmundo G, Kirschnick LB, Silveira FM, Martins MAT, Carlos R, Dos Santos JN, Fonseca FP, Vargas PA, Wagner VP, Martins MD
Head Neck Pathol 2022 Jun;16(2):525-537. Epub 2021 Dec 6 doi: 10.1007/s12105-021-01398-2. PMID: 34870796Free PMC Article
Peltrini R, Cantoni V, Green R, Lionetti R, D'Ambra M, Bartolini C, De Luca M, Bracale U, Cuocolo A, Corcione F
Surgeon 2021 Dec;19(6):e549-e558. Epub 2021 Feb 25 doi: 10.1016/j.surge.2021.01.010. PMID: 33640282
Wu Y, Xiong G, Zhang H, Wang M, Zhu F, Qin R
Endocr Pract 2021 Feb;27(2):152-157. Epub 2021 Feb 3 doi: 10.1016/j.eprac.2020.10.012. PMID: 33616046
Figiel JH, Viniol SG, Görlach J, Rinke A, Librizzi D, Mahnken AH
Rofo 2020 Feb;192(2):171-182. Epub 2019 Sep 11 doi: 10.1055/a-1001-2412. PMID: 31509861

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