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Lesion

MedGen UID:
65128
Concept ID:
C0221198
Finding
Synonym: Visible Lesion
SNOMED CT: Lesion (52988006)

Definition

A localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ, or body part. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLesion

Professional guidelines

PubMed

Charidimou A, Boulouis G, Frosch MP, Baron JC, Pasi M, Albucher JF, Banerjee G, Barbato C, Bonneville F, Brandner S, Calviere L, Caparros F, Casolla B, Cordonnier C, Delisle MB, Deramecourt V, Dichgans M, Gokcal E, Herms J, Hernandez-Guillamon M, Jäger HR, Jaunmuktane Z, Linn J, Martinez-Ramirez S, Martínez-Sáez E, Mawrin C, Montaner J, Moulin S, Olivot JM, Piazza F, Puy L, Raposo N, Rodrigues MA, Roeber S, Romero JR, Samarasekera N, Schneider JA, Schreiber S, Schreiber F, Schwall C, Smith C, Szalardy L, Varlet P, Viguier A, Wardlaw JM, Warren A, Wollenweber FA, Zedde M, van Buchem MA, Gurol ME, Viswanathan A, Al-Shahi Salman R, Smith EE, Werring DJ, Greenberg SM
Lancet Neurol 2022 Aug;21(8):714-725. doi: 10.1016/S1474-4422(22)00208-3. PMID: 35841910Free PMC Article
Waldman R, DeWane ME, Lu J
J Am Acad Dermatol 2020 Feb;82(2):283-296. Epub 2019 Jul 4 doi: 10.1016/j.jaad.2019.05.105. PMID: 31279813
Barkun AN, Almadi M, Kuipers EJ, Laine L, Sung J, Tse F, Leontiadis GI, Abraham NS, Calvet X, Chan FKL, Douketis J, Enns R, Gralnek IM, Jairath V, Jensen D, Lau J, Lip GYH, Loffroy R, Maluf-Filho F, Meltzer AC, Reddy N, Saltzman JR, Marshall JK, Bardou M
Ann Intern Med 2019 Dec 3;171(11):805-822. Epub 2019 Oct 22 doi: 10.7326/M19-1795. PMID: 31634917Free PMC Article

Recent clinical studies

Etiology

Segar DJ, Lak AM, Lee S, Harary M, Chavakula V, Lauro P, McDannold N, White J, Cosgrove GR
Brain 2021 Nov 29;144(10):3089-3100. doi: 10.1093/brain/awab176. PMID: 34750621
Renard D, Collombier L, Laurent-Chabalier S, Mura T, Le Floch A, Fertit HE, Thouvenot E, Guillamo JS
J Neurol 2021 Apr;268(4):1266-1275. Epub 2020 Oct 21 doi: 10.1007/s00415-020-10269-9. PMID: 33084938
Riemer K, Haukenes O, Kozak A
Tidsskr Nor Laegeforen 2019 Jan 15;139(1) Epub 2019 Jan 3 doi: 10.4045/tidsskr.18.0351. PMID: 30644680
Obrador R, Musulin S, Hansen B
J Vet Emerg Crit Care (San Antonio) 2015 Mar-Apr;25(2):187-99. Epub 2014 Nov 26 doi: 10.1111/vec.12252. PMID: 25428860
Majewski M, Susanne H, Klaus S
Knee 2006 Jun;13(3):184-8. Epub 2006 Apr 17 doi: 10.1016/j.knee.2006.01.005. PMID: 16603363

Diagnosis

Najafian B, Lusco MA, Alpers CE, Fogo AB
Am J Kidney Dis 2022 Jul;80(1):119-131. Epub 2022 Feb 4 doi: 10.1053/j.ajkd.2021.08.024. PMID: 35125261
Sonde N, Edwards M
Prim Dent J 2020 Dec;9(4):45-51. doi: 10.1177/2050168420963305. PMID: 33225855
Riemer K, Haukenes O, Kozak A
Tidsskr Nor Laegeforen 2019 Jan 15;139(1) Epub 2019 Jan 3 doi: 10.4045/tidsskr.18.0351. PMID: 30644680
Li H, Zhang F, Lei G
Chin Med J (Engl) 2014;127(7):1351-6. PMID: 24709193
Majewski M, Susanne H, Klaus S
Knee 2006 Jun;13(3):184-8. Epub 2006 Apr 17 doi: 10.1016/j.knee.2006.01.005. PMID: 16603363

Therapy

Nie T, Blair HA
CNS Drugs 2022 Oct;36(10):1133-1141. Epub 2022 Sep 7 doi: 10.1007/s40263-022-00949-7. PMID: 36070074Free PMC Article
Lodi G, Franchini R, Warnakulasuriya S, Varoni EM, Sardella A, Kerr AR, Carrassi A, MacDonald LC, Worthington HV
Cochrane Database Syst Rev 2016 Jul 29;7(7):CD001829. doi: 10.1002/14651858.CD001829.pub4. PMID: 27471845Free PMC Article
Smart KM, Wand BM, O'Connell NE
Cochrane Database Syst Rev 2016 Feb 24;2(2):CD010853. doi: 10.1002/14651858.CD010853.pub2. PMID: 26905470Free PMC Article
Provenzano E, Bossuyt V, Viale G, Cameron D, Badve S, Denkert C, MacGrogan G, Penault-Llorca F, Boughey J, Curigliano G, Dixon JM, Esserman L, Fastner G, Kuehn T, Peintinger F, von Minckwitz G, White J, Yang W, Symmans WF; Residual Disease Characterization Working Group of the Breast International Group-North American Breast Cancer Group Collaboration
Mod Pathol 2015 Sep;28(9):1185-201. Epub 2015 Jul 24 doi: 10.1038/modpathol.2015.74. PMID: 26205180
Corps KN, Roth TL, McGavern DB
JAMA Neurol 2015 Mar;72(3):355-62. doi: 10.1001/jamaneurol.2014.3558. PMID: 25599342Free PMC Article

Prognosis

Huang BT, Huang FY, Zuo ZL, Liu W, Huang KS, Liao YB, Wang PJ, Peng Y, Zhang C, Zhao ZG, Huang DJ, Chen M
Herz 2015 Dec;40(8):1097-106. Epub 2015 Jun 27 doi: 10.1007/s00059-015-4324-1. PMID: 26115740
Marrero JA
Curr Opin Gastroenterol 2005 May;21(3):308-12. doi: 10.1097/01.mog.0000159817.55661.ca. PMID: 15818151
Johnson TM, Hamilton T, Lowe L
J Am Acad Dermatol 1998 Sep;39(3):422-7. doi: 10.1016/s0190-9622(98)70318-4. PMID: 9738776
Gloster HM Jr, Brodland DG
Dermatol Surg 1996 Mar;22(3):217-26. doi: 10.1111/j.1524-4725.1996.tb00312.x. PMID: 8599733
Lillington GA
Dis Mon 1991 May;37(5):271-318. doi: 10.1016/s0011-5029(05)80012-4. PMID: 2019220

Clinical prediction guides

Hernández Montilla I, Medela A, Mac Carthy T, Aguilar A, Gómez Tejerina P, Vilas Sueiro A, González Pérez AM, Vergara de la Campa L, Luna Bastante L, García Castro R, Alfageme Roldán F
Skin Res Technol 2023 Jun;29(6):e13357. doi: 10.1111/srt.13357. PMID: 37357665Free PMC Article
López-Mora DA, Flotats A, Fuentes-Ocampo F, Camacho V, Fernández A, Ruiz A, Duch J, Sizova M, Domènech A, Estorch M, Carrió I
Eur J Nucl Med Mol Imaging 2019 Jun;46(6):1383-1390. Epub 2019 Jan 10 doi: 10.1007/s00259-019-4260-z. PMID: 30631910
Seo SG, Kim JS, Seo DK, Kim YK, Lee SH, Lee HS
Acta Orthop 2018 Aug;89(4):462-467. Epub 2018 Apr 11 doi: 10.1080/17453674.2018.1460777. PMID: 29635971Free PMC Article
Wortsman X, Claveria P, Valenzuela F, Molina MT, Wortsman J
J Ultrasound Med 2014 Jan;33(1):93-102. doi: 10.7863/ultra.33.1.93. PMID: 24371103
Estrela C, Bueno MR, Azevedo BC, Azevedo JR, Pécora JD
J Endod 2008 Nov;34(11):1325-1331. Epub 2008 Sep 17 doi: 10.1016/j.joen.2008.08.013. PMID: 18928840

Recent systematic reviews

Tzoumas N, Riding G, Williams MA, Steel DH
Cochrane Database Syst Rev 2023 Jun 14;6(6):CD009300. doi: 10.1002/14651858.CD009300.pub3. PMID: 37314061Free PMC Article
Proschinger S, Kuhwand P, Rademacher A, Walzik D, Warnke C, Zimmer P, Joisten N
J Neurol 2022 Jun;269(6):2922-2940. Epub 2022 Jan 27 doi: 10.1007/s00415-021-10935-6. PMID: 35084560Free PMC Article
Ferreira Jr LH Jr, Mendonça Jr KD Jr, Chaves de Souza J, Soares Dos Reis DC, do Carmo Faleiros Veloso Guedes C, de Souza Castro Filice L, Bruzadelli Macedo S, Soares Rocha F
Minerva Dent Oral Sci 2021 Feb;70(1):49-57. Epub 2020 Sep 22 doi: 10.23736/S2724-6329.20.04306-X. PMID: 32960522
Coll JA, Vargas K, Marghalani AA, Chen CY, AlShamali S, Dhar V, Crystal YO
Pediatr Dent 2020 Jul 15;42(4):256-461. PMID: 32847665
Hegedus EJ, Goode AP, Cook CE, Michener L, Myer CA, Myer DM, Wright AA
Br J Sports Med 2012 Nov;46(14):964-78. Epub 2012 Jul 7 doi: 10.1136/bjsports-2012-091066. PMID: 22773322

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