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Liver calculus

MedGen UID:
657845
Concept ID:
C0574143
Finding
Synonyms: Hepatolith; Hepatolithiasis
SNOMED CT: Liver calculus (297288000); Hepatolith (297288000)

Definition

The presence of solitary or multiple stones in the intrahepatic bile ducts. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLiver calculus

Professional guidelines

PubMed

Simpson TC, Clarkson JE, Worthington HV, MacDonald L, Weldon JC, Needleman I, Iheozor-Ejiofor Z, Wild SH, Qureshi A, Walker A, Patel VA, Boyers D, Twigg J
Cochrane Database Syst Rev 2022 Apr 14;4(4):CD004714. doi: 10.1002/14651858.CD004714.pub4. PMID: 35420698Free PMC Article
Pisano M, Allievi N, Gurusamy K, Borzellino G, Cimbanassi S, Boerna D, Coccolini F, Tufo A, Di Martino M, Leung J, Sartelli M, Ceresoli M, Maier RV, Poiasina E, De Angelis N, Magnone S, Fugazzola P, Paolillo C, Coimbra R, Di Saverio S, De Simone B, Weber DG, Sakakushev BE, Lucianetti A, Kirkpatrick AW, Fraga GP, Wani I, Biffl WL, Chiara O, Abu-Zidan F, Moore EE, Leppäniemi A, Kluger Y, Catena F, Ansaloni L
World J Emerg Surg 2020 Nov 5;15(1):61. doi: 10.1186/s13017-020-00336-x. PMID: 33153472Free PMC Article
Jin S, Fu Q, Wuyun G, Wuyun T
World J Gastroenterol 2013 Nov 28;19(44):7983-91. doi: 10.3748/wjg.v19.i44.7983. PMID: 24307791Free PMC Article

Recent clinical studies

Etiology

Unalp-Arida A, Ruhl CE
Hepatology 2023 Jun 1;77(6):1882-1895. Epub 2023 Jan 13 doi: 10.1097/HEP.0000000000000264. PMID: 36631004
Manes G, Paspatis G, Aabakken L, Anderloni A, Arvanitakis M, Ah-Soune P, Barthet M, Domagk D, Dumonceau JM, Gigot JF, Hritz I, Karamanolis G, Laghi A, Mariani A, Paraskeva K, Pohl J, Ponchon T, Swahn F, Ter Steege RWF, Tringali A, Vezakis A, Williams EJ, van Hooft JE
Endoscopy 2019 May;51(5):472-491. Epub 2019 Apr 3 doi: 10.1055/a-0862-0346. PMID: 30943551
Di Ciaula A, Garruti G, Wang DQ, Portincasa P
Eur J Intern Med 2018 Jul;53:3-11. Epub 2018 Apr 26 doi: 10.1016/j.ejim.2018.04.019. PMID: 29706426Free PMC Article
Lammert F, Gurusamy K, Ko CW, Miquel JF, Méndez-Sánchez N, Portincasa P, van Erpecum KJ, van Laarhoven CJ, Wang DQ
Nat Rev Dis Primers 2016 Apr 28;2:16024. doi: 10.1038/nrdp.2016.24. PMID: 27121416
Schirmer BD, Winters KL, Edlich RF
J Long Term Eff Med Implants 2005;15(3):329-38. doi: 10.1615/jlongtermeffmedimplants.v15.i3.90. PMID: 16022643

Diagnosis

Ceci L, Han Y, Krutsinger K, Baiocchi L, Wu N, Kundu D, Kyritsi K, Zhou T, Gaudio E, Francis H, Alpini G, Kennedy L
Compr Physiol 2023 Jun 26;13(3):4909-4943. doi: 10.1002/cphy.c220028. PMID: 37358507
Manes G, Paspatis G, Aabakken L, Anderloni A, Arvanitakis M, Ah-Soune P, Barthet M, Domagk D, Dumonceau JM, Gigot JF, Hritz I, Karamanolis G, Laghi A, Mariani A, Paraskeva K, Pohl J, Ponchon T, Swahn F, Ter Steege RWF, Tringali A, Vezakis A, Williams EJ, van Hooft JE
Endoscopy 2019 May;51(5):472-491. Epub 2019 Apr 3 doi: 10.1055/a-0862-0346. PMID: 30943551
Lammert F, Gurusamy K, Ko CW, Miquel JF, Méndez-Sánchez N, Portincasa P, van Erpecum KJ, van Laarhoven CJ, Wang DQ
Nat Rev Dis Primers 2016 Apr 28;2:16024. doi: 10.1038/nrdp.2016.24. PMID: 27121416
European Association for the Study of the Liver (EASL). Electronic address: easloffice@easloffice.eu
J Hepatol 2016 Jul;65(1):146-181. Epub 2016 Apr 13 doi: 10.1016/j.jhep.2016.03.005. PMID: 27085810
Schirmer BD, Winters KL, Edlich RF
J Long Term Eff Med Implants 2005;15(3):329-38. doi: 10.1615/jlongtermeffmedimplants.v15.i3.90. PMID: 16022643

Therapy

Li P, Pang Y, He S, Duan J, Gong H, Yan Y, Shi J
Sci Rep 2023 Dec 9;13(1):21821. doi: 10.1038/s41598-023-48610-7. PMID: 38071316Free PMC Article
McNeice A, Scott R, Rafferty GP, Cash WJ, Turner GB
Ir J Med Sci 2019 Feb;188(1):109-117. Epub 2018 May 31 doi: 10.1007/s11845-018-1836-8. PMID: 29850987
Khuroo MS, Rather AA, Khuroo NS, Khuroo MS
World J Gastroenterol 2016 Sep 21;22(35):7973-82. doi: 10.3748/wjg.v22.i35.7973. PMID: 27672292Free PMC Article
Johnson CD, Besselink MG, Carter R
BMJ 2014 Aug 12;349:g4859. doi: 10.1136/bmj.g4859. PMID: 25116169
Okuda K
Lab Res Methods Biol Med 1983;7:405-23. PMID: 6353110

Prognosis

Unalp-Arida A, Ruhl CE
Hepatology 2023 Jun 1;77(6):1882-1895. Epub 2023 Jan 13 doi: 10.1097/HEP.0000000000000264. PMID: 36631004
van As AB, Millar AJ
Pediatr Surg Int 2017 Apr;33(4):445-453. Epub 2016 Dec 27 doi: 10.1007/s00383-016-4046-3. PMID: 28028561
Hayakawa T, Jin CX, Ko SB, Kitagawa M, Ishiguro H
Intern Med 2009;48(15):1251-4. Epub 2009 Aug 3 doi: 10.2169/internalmedicine.48.2199. PMID: 19652425
Schirmer BD, Winters KL, Edlich RF
J Long Term Eff Med Implants 2005;15(3):329-38. doi: 10.1615/jlongtermeffmedimplants.v15.i3.90. PMID: 16022643
Tandon RK, Garg PK
Dig Dis 2004;22(3):258-66. doi: 10.1159/000082797. PMID: 15753608

Clinical prediction guides

Wannous H
Pediatr Nephrol 2023 Aug;38(8):2643-2648. Epub 2023 Mar 14 doi: 10.1007/s00467-023-05917-x. PMID: 36917293
Unalp-Arida A, Ruhl CE
Hepatology 2023 Jun 1;77(6):1882-1895. Epub 2023 Jan 13 doi: 10.1097/HEP.0000000000000264. PMID: 36631004
Pisano M, Allievi N, Gurusamy K, Borzellino G, Cimbanassi S, Boerna D, Coccolini F, Tufo A, Di Martino M, Leung J, Sartelli M, Ceresoli M, Maier RV, Poiasina E, De Angelis N, Magnone S, Fugazzola P, Paolillo C, Coimbra R, Di Saverio S, De Simone B, Weber DG, Sakakushev BE, Lucianetti A, Kirkpatrick AW, Fraga GP, Wani I, Biffl WL, Chiara O, Abu-Zidan F, Moore EE, Leppäniemi A, Kluger Y, Catena F, Ansaloni L
World J Emerg Surg 2020 Nov 5;15(1):61. doi: 10.1186/s13017-020-00336-x. PMID: 33153472Free PMC Article
Jin S, Fu Q, Wuyun G, Wuyun T
World J Gastroenterol 2013 Nov 28;19(44):7983-91. doi: 10.3748/wjg.v19.i44.7983. PMID: 24307791Free PMC Article
Schirmer BD, Winters KL, Edlich RF
J Long Term Eff Med Implants 2005;15(3):329-38. doi: 10.1615/jlongtermeffmedimplants.v15.i3.90. PMID: 16022643

Recent systematic reviews

Hall L, Halle-Smith J, Evans R, Toogood G, Wiggins T, Markar SR, Kapoulas S, Super P, Tucker O, McKay SC
BJS Open 2023 Mar 7;7(2) doi: 10.1093/bjsopen/zrac152. PMID: 36952251Free PMC Article
Massironi S, Fanetti I, Viganò C, Pirola L, Fichera M, Cristoferi L, Capurso G, Invernizzi P, Danese S
Aliment Pharmacol Ther 2022 Jun;55(12):1478-1491. Epub 2022 May 3 doi: 10.1111/apt.16949. PMID: 35505465Free PMC Article
Simpson TC, Clarkson JE, Worthington HV, MacDonald L, Weldon JC, Needleman I, Iheozor-Ejiofor Z, Wild SH, Qureshi A, Walker A, Patel VA, Boyers D, Twigg J
Cochrane Database Syst Rev 2022 Apr 14;4(4):CD004714. doi: 10.1002/14651858.CD004714.pub4. PMID: 35420698Free PMC Article
Qin S, Wang S, Wang X, Wang J
Medicine (Baltimore) 2018 Aug;97(35):e12092. doi: 10.1097/MD.0000000000012092. PMID: 30170429Free PMC Article
Jaruvongvanich V, Sanguankeo A, Upala S
Dig Dis Sci 2016 Aug;61(8):2389-2396. Epub 2016 Mar 18 doi: 10.1007/s10620-016-4125-2. PMID: 26993825

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