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Anorgasmia

MedGen UID:
65860
•Concept ID:
C0234022
•
Mental or Behavioral Dysfunction
Synonym: Orgasm incapacity
SNOMED CT: Orgasm incapacity (62607004); Anorgasmia (62607004)
 
HPO: HP:0046502

Definition

Inability of individual to reach orgasm. [from HPO]

Professional guidelines

PubMed

Psychological and Behavioral Treatment of Female Orgasmic Disorder.
Marchand E
Sex Med Rev 2021 Apr;9(2):194-211. Epub 2020 Oct 14 doi: 10.1016/j.sxmr.2020.07.007. PMID: 33069622
Management Options for Premature Ejaculation and Delayed Ejaculation in Men.
Martin-Tuite P, Shindel AW
Sex Med Rev 2020 Jul;8(3):473-485. Epub 2019 Oct 23 doi: 10.1016/j.sxmr.2019.09.002. PMID: 31668585
Female sexual health consensus clinical guidelines.
Lamont J; CONTRIBUTING AUTHORS
J Obstet Gynaecol Can 2012 Aug;34(8):769-775. doi: 10.1016/S1701-2163(16)35341-5. PMID: 22947409

Recent clinical studies

Etiology

The Impact of Body Awareness on Women's Sexual Health: A Comprehensive Review.
Seal BN, Meston CM
Sex Med Rev 2020 Apr;8(2):242-255. Epub 2018 Apr 18 doi: 10.1016/j.sxmr.2018.03.003. PMID: 29678474
Topiramate-associated sexual dysfunction: A systematic review.
Chen LW, Chen MY, Chen KY, Lin HS, Chien CC, Yin HL
Epilepsy Behav 2017 Aug;73:10-17. Epub 2017 Jun 9 doi: 10.1016/j.yebeh.2017.05.014. PMID: 28605628
Tramadol Abuse and Sexual Function.
Abdel-Hamid IA, Andersson KE, Waldinger MD, Anis TH
Sex Med Rev 2016 Jul;4(3):235-246. Epub 2016 Mar 19 doi: 10.1016/j.sxmr.2015.10.014. PMID: 27871957
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
Sexual Dysfunction in Women: A Practical Approach.
Faubion SS, Rullo JE
Am Fam Physician 2015 Aug 15;92(4):281-8. PMID: 26280233

Diagnosis

The Lost Penis Syndrome: A New Clinical Entity in Sexual Medicine.
Colonnello E, Limoncin E, Ciocca G, Sansone A, Mollaioli D, Balercia G, Porst H, Zhang H, Yu X, Zhang Y, Jannini EA
Sex Med Rev 2022 Jan;10(1):113-129. Epub 2021 Oct 5 doi: 10.1016/j.sxmr.2021.08.001. PMID: 34620562
History of the Treatment of Female Sexual Dysfunction(s).
Kleinplatz PJ
Annu Rev Clin Psychol 2018 May 7;14:29-54. Epub 2018 Jan 22 doi: 10.1146/annurev-clinpsy-050817-084802. PMID: 29356577
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
Sexual Dysfunction in Women: A Practical Approach.
Faubion SS, Rullo JE
Am Fam Physician 2015 Aug 15;92(4):281-8. PMID: 26280233
Women's orgasm.
Meston CM, Levin RJ, Sipski ML, Hull EM, Heiman JR
Annu Rev Sex Res 2004;15:173-257. PMID: 16913280

Therapy

Neglected side effects to curative prostate cancer treatments.
Nolsøe AB, Jensen CFS, Østergren PB, Fode M
Int J Impot Res 2021 May;33(4):428-438. Epub 2020 Dec 14 doi: 10.1038/s41443-020-00386-4. PMID: 33318637
Management Options for Premature Ejaculation and Delayed Ejaculation in Men.
Martin-Tuite P, Shindel AW
Sex Med Rev 2020 Jul;8(3):473-485. Epub 2019 Oct 23 doi: 10.1016/j.sxmr.2019.09.002. PMID: 31668585
Male Orgasmic Dysfunction Post-Radical Pelvic Surgery.
Haney NM, Alzweri LM, Hellstrom WJG
Sex Med Rev 2018 Jul;6(3):429-437. Epub 2018 Feb 12 doi: 10.1016/j.sxmr.2017.12.003. PMID: 29396282
Orgasmic Dysfunction Following Radical Prostatectomy: Review of Current Literature.
Clavell-Hernández J, Martin C, Wang R
Sex Med Rev 2018 Jan;6(1):124-134. Epub 2017 Nov 3 doi: 10.1016/j.sxmr.2017.09.003. PMID: 29108976
Sexual Dysfunction in Women: A Practical Approach.
Faubion SS, Rullo JE
Am Fam Physician 2015 Aug 15;92(4):281-8. PMID: 26280233

Prognosis

Characterization of Female Sexual Dysfunction Associated with Spinal Pathology and Surgery.
Moscicki P, Bachmann GA
Sex Med Rev 2022 Oct 1;10(4):493-498. doi: 10.1016/j.sxmr.2022.01.003. PMID: 37051949
Characterization of Female Sexual Dysfunction Associated with Spinal Pathology and Surgery.
Moscicki P, Bachmann GA
Sex Med Rev 2022 Oct;10(4):493-498. Epub 2022 Jul 16 doi: 10.1016/j.sxmr.2022.01.003. PMID: 35853824
Cultural anorgasmia: considerations in the evaluation of male infertility in the Hasidic community.
Dubowitch E, Khurgin J
Can J Urol 2019 Aug;26(4):9864-9866. PMID: 31469644
Brain Activity Unique to Orgasm in Women: An fMRI Analysis.
Wise NJ, Frangos E, Komisaruk BR
J Sex Med 2017 Nov;14(11):1380-1391. Epub 2017 Oct 3 doi: 10.1016/j.jsxm.2017.08.014. PMID: 28986148Free PMC Article
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article

Clinical prediction guides

Characterization of Female Sexual Dysfunction Associated with Spinal Pathology and Surgery.
Moscicki P, Bachmann GA
Sex Med Rev 2022 Oct 1;10(4):493-498. doi: 10.1016/j.sxmr.2022.01.003. PMID: 37051949
Characterization of Female Sexual Dysfunction Associated with Spinal Pathology and Surgery.
Moscicki P, Bachmann GA
Sex Med Rev 2022 Oct;10(4):493-498. Epub 2022 Jul 16 doi: 10.1016/j.sxmr.2022.01.003. PMID: 35853824
Topiramate-associated sexual dysfunction: A systematic review.
Chen LW, Chen MY, Chen KY, Lin HS, Chien CC, Yin HL
Epilepsy Behav 2017 Aug;73:10-17. Epub 2017 Jun 9 doi: 10.1016/j.yebeh.2017.05.014. PMID: 28605628
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
Female sexual health consensus clinical guidelines.
Lamont J; CONTRIBUTING AUTHORS
J Obstet Gynaecol Can 2012 Aug;34(8):769-775. doi: 10.1016/S1701-2163(16)35341-5. PMID: 22947409

Recent systematic reviews

Persistent sexual dysfunction after SSRI withdrawal: a scoping review and presentation of 86 cases from the Netherlands.
Chinchilla Alfaro K, van Hunsel F, Ekhart C
Expert Opin Drug Saf 2022 Apr;21(4):553-561. Epub 2021 Nov 27 doi: 10.1080/14740338.2022.2007883. PMID: 34791958
Erectile and Ejaculatory Dysfunction Associated with Use of Psychotropic Drugs: A Systematic Review.
Trinchieri M, Trinchieri M, Perletti G, Magri V, Stamatiou K, Cai T, Montanari E, Trinchieri A
J Sex Med 2021 Aug;18(8):1354-1363. Epub 2021 Jul 8 doi: 10.1016/j.jsxm.2021.05.016. PMID: 34247952
Drug-Associated Spontaneous Orgasm: A Case Report and Systematic Review of Literature.
Chen WH, Chu YH, Chen KY
Clin Neuropharmacol 2018 Jan/Feb;41(1):31-37. doi: 10.1097/WNF.0000000000000259. PMID: 29194112
Topiramate-associated sexual dysfunction: A systematic review.
Chen LW, Chen MY, Chen KY, Lin HS, Chien CC, Yin HL
Epilepsy Behav 2017 Aug;73:10-17. Epub 2017 Jun 9 doi: 10.1016/j.yebeh.2017.05.014. PMID: 28605628
A systematic review of the literature on female sexual dysfunction prevalence and predictors.
West SL, Vinikoor LC, Zolnoun D
Annu Rev Sex Res 2004;15:40-172. PMID: 16913279

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