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Pulmonary Granuloma

MedGen UID:
65908
•Concept ID:
C0235557
•
Finding
Synonyms: Lung Granuloma; Pulmonary granuloma
SNOMED CT: Pulmonary granuloma (101401000119103)

Definition

A granuloma that is located in lung tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPulmonary Granuloma

Professional guidelines

PubMed

Clinical manifestations and treatment of Wegener's granulomatosis.
Holle JU, Laudien M, Gross WL
Rheum Dis Clin North Am 2010 Aug;36(3):507-26. doi: 10.1016/j.rdc.2010.05.008. PMID: 20688247

Recent clinical studies

Etiology

Pulmonary involvement of ANCA-associated vasculitis in adult Chinese patients.
Zhou P, Li Z, Gao L, Que C, Li H, Ma J, Wang G, Chen M
BMC Pulm Med 2022 Jan 12;22(1):35. doi: 10.1186/s12890-022-01829-y. PMID: 35022009Free PMC Article
Pulmonary involvements of anti-neutrophil cytoplasmic autoantibody-associated renal vasculitis in Japan.
Hirayama K, Kobayashi M, Usui J, Arimura Y, Sugiyama H, Nitta K, Muso E, Wada T, Matsuo S, Yamagata K; Japanese RPGN Study Group of Progressive Renal Disease
Nephrol Dial Transplant 2015 Apr;30 Suppl 1:i83-93. Epub 2015 Jan 22 doi: 10.1093/ndt/gfu385. PMID: 25613541
Inflammatory markers and pulmonary granuloma infiltration in sarcoidosis.
Terčelj M, Salobir B, Zupancic M, Wraber B, Rylander R
Respirology 2014 Feb;19(2):225-230. Epub 2013 Dec 24 doi: 10.1111/resp.12199. PMID: 24372709
Leptospirosis and tularaemia in raccoons (Procyon lotor) of Larimer County, [corrected] Colorado.
Duncan C, Krafsur G, Podell B, Baeten LA, LeVan I, Charles B, Ehrhart EJ
Zoonoses Public Health 2012 Feb;59(1):29-34. Epub 2011 Apr 20 doi: 10.1111/j.1863-2378.2011.01412.x. PMID: 21824365
Solitary pulmonary granuloma caused by Mycobacterium avium-intracellulare complex.
Yonemori K, Tateishi U, Tsuta K, Yonemori Y, Uno H, Asamura H, Kusumoto M
Int J Tuberc Lung Dis 2007 Feb;11(2):215-21. PMID: 17263294

Diagnosis

Pulmonary involvement of ANCA-associated vasculitis in adult Chinese patients.
Zhou P, Li Z, Gao L, Que C, Li H, Ma J, Wang G, Chen M
BMC Pulm Med 2022 Jan 12;22(1):35. doi: 10.1186/s12890-022-01829-y. PMID: 35022009Free PMC Article
Risk factors for human heartworm infections (dirofilariasis) in the South.
Diaz JH, Risher WH
J La State Med Soc 2015 Mar-Apr;167(2):79-86. Epub 2015 Apr 15 PMID: 25978057
Solitary pulmonary granuloma caused by Mycobacterium avium-intracellulare complex.
Yonemori K, Tateishi U, Tsuta K, Yonemori Y, Uno H, Asamura H, Kusumoto M
Int J Tuberc Lung Dis 2007 Feb;11(2):215-21. PMID: 17263294
The role of osteopontin in lung disease.
O'Regan A
Cytokine Growth Factor Rev 2003 Dec;14(6):479-88. doi: 10.1016/s1359-6101(03)00055-8. PMID: 14563350
Neutrophils and reactive oxygen intermediates mediate glucan-induced pulmonary granuloma formation through the local induction of monocyte chemoattractant protein-1.
Kilgore KS, Imlay MM, Szaflarski JP, Silverstein FS, Malani AN, Evans VM, Warren JS
Lab Invest 1997 Feb;76(2):191-201. PMID: 9042155

Therapy

Erythema Nodosum as the Initial Presentation of Nivolumab-Induced Sarcoidosis-Like Reaction.
Laroche A, Alarcon Chinchilla E, Bourgeault E, Doré MA
J Cutan Med Surg 2018 Nov/Dec;22(6):627-629. Epub 2018 May 17 doi: 10.1177/1203475418776934. PMID: 29772919
Aspergillus Vertebral Osteomyelitis Complicating Pulmonary Granuloma in an Immunocompetent Adult.
Li Y, Cen Y, Luo Y, Zhu Z, Min S, Chen X
Med Princ Pract 2016;25(4):394-6. Epub 2015 Dec 14 doi: 10.1159/000443310. PMID: 26667988Free PMC Article
A case of postoperative hepatic granuloma presumptively caused by surgical staples/clipping materials.
Nihon-Yanagi Y, Ishiwatari T, Otsuka Y, Okubo Y, Tochigi N, Wakayama M, Nemoto T, Watanabe M, Kaneko H, Sumino Y, Shibuya K
Diagn Pathol 2015 Jul 9;10:90. doi: 10.1186/s13000-015-0291-3. PMID: 26156756Free PMC Article
Urease and Helicobacter spp. antigens in pulmonary granuloma.
Herndon B, Quinn T, Wasson N, Nzabi M, Molteni A
J Comp Pathol 2013 Feb;148(2-3):266-77. Epub 2012 Aug 14 doi: 10.1016/j.jcpa.2012.06.011. PMID: 22901429
Clinical manifestations and treatment of Wegener's granulomatosis.
Holle JU, Laudien M, Gross WL
Rheum Dis Clin North Am 2010 Aug;36(3):507-26. doi: 10.1016/j.rdc.2010.05.008. PMID: 20688247

Prognosis

Pulmonary involvement of ANCA-associated vasculitis in adult Chinese patients.
Zhou P, Li Z, Gao L, Que C, Li H, Ma J, Wang G, Chen M
BMC Pulm Med 2022 Jan 12;22(1):35. doi: 10.1186/s12890-022-01829-y. PMID: 35022009Free PMC Article
Pulmonary involvements of anti-neutrophil cytoplasmic autoantibody-associated renal vasculitis in Japan.
Hirayama K, Kobayashi M, Usui J, Arimura Y, Sugiyama H, Nitta K, Muso E, Wada T, Matsuo S, Yamagata K; Japanese RPGN Study Group of Progressive Renal Disease
Nephrol Dial Transplant 2015 Apr;30 Suppl 1:i83-93. Epub 2015 Jan 22 doi: 10.1093/ndt/gfu385. PMID: 25613541
Inflammatory markers and pulmonary granuloma infiltration in sarcoidosis.
Terčelj M, Salobir B, Zupancic M, Wraber B, Rylander R
Respirology 2014 Feb;19(2):225-230. Epub 2013 Dec 24 doi: 10.1111/resp.12199. PMID: 24372709
Detection of experimentally induced pulmonary granuloma inflammation in monocyte chemoattractant protein-1 reporter mice.
Rajasekaran S, Kao VY, Chen MR, Yang AL, Hsu CH, Chen CT, Lin KM
Mol Imaging Biol 2010 Apr;12(2):163-73. Epub 2009 Oct 6 doi: 10.1007/s11307-009-0261-9. PMID: 19806405
Adalimumab-induced noncaseating granuloma in the bone marrow of a patient being treated for rheumatoid arthritis.
Metyas SK, Tadros RM, Arkfeld DG
Rheumatol Int 2009 Feb;29(4):437-9. Epub 2008 Sep 2 doi: 10.1007/s00296-008-0691-8. PMID: 18762943

Clinical prediction guides

Emerging insights in sarcoidosis: moving forward through reverse translational research.
Liu A, Sharma L, Yan X, Dela Cruz CS, Herzog EL, Ryu C
Am J Physiol Lung Cell Mol Physiol 2022 Apr 1;322(4):L518-L525. Epub 2022 Feb 23 doi: 10.1152/ajplung.00266.2021. PMID: 35196896Free PMC Article
Small pulmonary granuloma is often misdiagnosed as lung cancer by positron emission tomography/computer tomography in diabetic patients.
Lu T, Zhan C, Huang Y, Zhao M, Yang X, Ge D, Shi Y, Wang Q
Interact Cardiovasc Thorac Surg 2019 Mar 1;28(3):394-398. doi: 10.1093/icvts/ivy263. PMID: 30165660
Pulmonary involvements of anti-neutrophil cytoplasmic autoantibody-associated renal vasculitis in Japan.
Hirayama K, Kobayashi M, Usui J, Arimura Y, Sugiyama H, Nitta K, Muso E, Wada T, Matsuo S, Yamagata K; Japanese RPGN Study Group of Progressive Renal Disease
Nephrol Dial Transplant 2015 Apr;30 Suppl 1:i83-93. Epub 2015 Jan 22 doi: 10.1093/ndt/gfu385. PMID: 25613541
Urease and Helicobacter spp. antigens in pulmonary granuloma.
Herndon B, Quinn T, Wasson N, Nzabi M, Molteni A
J Comp Pathol 2013 Feb;148(2-3):266-77. Epub 2012 Aug 14 doi: 10.1016/j.jcpa.2012.06.011. PMID: 22901429
The role of cytokines in the formation of the schistosome egg granuloma.
Boros DL
Immunobiology 1994 Oct;191(4-5):441-50. doi: 10.1016/S0171-2985(11)80450-X. PMID: 7713558

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