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Scrotal pain

MedGen UID:
65926
•Concept ID:
C0236078
•
Sign or Symptom
Synonyms: Pain in scrotum; Pain of scrotum; Scrotal Pain
SNOMED CT: Pain of scrotum (20502007); Scrotal pain (20502007); Pain in scrotum (20502007)
 
HPO: HP:0030155

Definition

An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the scrotum. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVScrotal pain

Professional guidelines

PubMed

Management of chronic primary pelvic pain syndromes.
Parsons BA, Baranowski AP, Berghmans B, Borovicka J, Cottrell AM, Dinis-Oliveira P, Elneil S, Hughes J, Messelink BEJ, de C Williams AC, Abreu-Mendes P, Zumstein V, Engeler DS
BJU Int 2022 May;129(5):572-581. Epub 2021 Oct 27 doi: 10.1111/bju.15609. PMID: 34617386
Scrotal pain: evaluation and management.
Gordhan CG, Sadeghi-Nejad H
Korean J Urol 2015 Jan;56(1):3-11. Epub 2015 Jan 12 doi: 10.4111/kju.2015.56.1.3. PMID: 25598931Free PMC Article
Testicular torsion: diagnosis, evaluation, and management.
Sharp VJ, Kieran K, Arlen AM
Am Fam Physician 2013 Dec 15;88(12):835-40. PMID: 24364548

Recent clinical studies

Etiology

Diagnosing with a TWIST: Systematic Review and Meta-Analysis of a Testicular Torsion Risk Score.
Qin KR, Qu LG
J Urol 2022 Jul;208(1):62-70. Epub 2022 Mar 3 doi: 10.1097/JU.0000000000002496. PMID: 35238603
Management of chronic primary pelvic pain syndromes.
Parsons BA, Baranowski AP, Berghmans B, Borovicka J, Cottrell AM, Dinis-Oliveira P, Elneil S, Hughes J, Messelink BEJ, de C Williams AC, Abreu-Mendes P, Zumstein V, Engeler DS
BJU Int 2022 May;129(5):572-581. Epub 2021 Oct 27 doi: 10.1111/bju.15609. PMID: 34617386
Pediatric Testicular Torsion.
Bowlin PR, Gatti JM, Murphy JP
Surg Clin North Am 2017 Feb;97(1):161-172. doi: 10.1016/j.suc.2016.08.012. PMID: 27894425
Epididymitis: An Overview.
McConaghy JR, Panchal B
Am Fam Physician 2016 Nov 1;94(9):723-726. PMID: 27929243
Epididymitis.
Taylor SN
Clin Infect Dis 2015 Dec 15;61 Suppl 8:S770-3. doi: 10.1093/cid/civ812. PMID: 26602616

Diagnosis

Diagnosing with a TWIST: Systematic Review and Meta-Analysis of a Testicular Torsion Risk Score.
Qin KR, Qu LG
J Urol 2022 Jul;208(1):62-70. Epub 2022 Mar 3 doi: 10.1097/JU.0000000000002496. PMID: 35238603
Management of chronic primary pelvic pain syndromes.
Parsons BA, Baranowski AP, Berghmans B, Borovicka J, Cottrell AM, Dinis-Oliveira P, Elneil S, Hughes J, Messelink BEJ, de C Williams AC, Abreu-Mendes P, Zumstein V, Engeler DS
BJU Int 2022 May;129(5):572-581. Epub 2021 Oct 27 doi: 10.1111/bju.15609. PMID: 34617386
Epididymitis.
Taylor SN
Clin Infect Dis 2015 Dec 15;61 Suppl 8:S770-3. doi: 10.1093/cid/civ812. PMID: 26602616
Testicular torsion: diagnosis, evaluation, and management.
Sharp VJ, Kieran K, Arlen AM
Am Fam Physician 2013 Dec 15;88(12):835-40. PMID: 24364548
Acute scrotal pain.
Srinath H
Aust Fam Physician 2013 Nov;42(11):790-2. PMID: 24217099

Therapy

Genitourinary Emergencies in Older Adults.
Soria N, Khoujah D
Emerg Med Clin North Am 2021 May;39(2):361-378. Epub 2021 Mar 11 doi: 10.1016/j.emc.2021.01.003. PMID: 33863465
Epididymitis: An Overview.
McConaghy JR, Panchal B
Am Fam Physician 2016 Nov 1;94(9):723-726. PMID: 27929243
Genitofemoral neuralgia: a review.
Cesmebasi A, Yadav A, Gielecki J, Tubbs RS, Loukas M
Clin Anat 2015 Jan;28(1):128-35. Epub 2014 Nov 5 doi: 10.1002/ca.22481. PMID: 25377757
Scalpel versus no-scalpel incision for vasectomy.
Cook LA, Pun A, Gallo MF, Lopez LM, Van Vliet HA
Cochrane Database Syst Rev 2014 Mar 30;2014(3):CD004112. doi: 10.1002/14651858.CD004112.pub4. PMID: 24683021Free PMC Article
Osteitis pubis in athletes.
Beatty T
Curr Sports Med Rep 2012 Mar-Apr;11(2):96-8. doi: 10.1249/JSR.0b013e318249c32b. PMID: 22410702

Prognosis

Microsurgical Denervation of the Spermatic Cord: A Historical Perspective and Recent Developments.
Sun HH, Tay KS, Jesse E, Muncey W, Loeb A, Thirumavalavan N
Sex Med Rev 2022 Oct 1;10(4):791-799. doi: 10.1016/j.sxmr.2021.11.005. PMID: 37051952
Microsurgical Denervation of the Spermatic Cord: A Historical Perspective and Recent Developments.
Sun HH, Tay KS, Jesse E, Muncey W, Loeb A, Thirumavalavan N
Sex Med Rev 2022 Oct;10(4):791-799. Epub 2022 Jan 5 doi: 10.1016/j.sxmr.2021.11.005. PMID: 34996747
Blunt Scrotal Trauma in Soldiers-Epidemiology and Outcome.
Rottenstreich M, Gofrit ON
Mil Med 2017 Sep;182(9):e1929-e1931. doi: 10.7205/MILMED-D-16-00375. PMID: 28885957
Thrombotic and Nonthrombotic Types of Intratesticular Varicoceles: Value of Sonography for the Diagnosis.
Ünal E
J Ultrasound Med 2017 Nov;36(11):2355-2360. Epub 2017 Jun 8 doi: 10.1002/jum.14281. PMID: 28593638
Primary testicular lymphoma.
Vitolo U, Ferreri AJ, Zucca E
Crit Rev Oncol Hematol 2008 Feb;65(2):183-9. Epub 2007 Oct 24 doi: 10.1016/j.critrevonc.2007.08.005. PMID: 17962036

Clinical prediction guides

High risk and low prevalence diseases: Testicular torsion.
Lacy A, Smith A, Koyfman A, Long B
Am J Emerg Med 2023 Apr;66:98-104. Epub 2023 Jan 24 doi: 10.1016/j.ajem.2023.01.031. PMID: 36738571
Microsurgical Denervation of the Spermatic Cord: A Historical Perspective and Recent Developments.
Sun HH, Tay KS, Jesse E, Muncey W, Loeb A, Thirumavalavan N
Sex Med Rev 2022 Oct 1;10(4):791-799. doi: 10.1016/j.sxmr.2021.11.005. PMID: 37051952
Diagnosing with a TWIST: Systematic Review and Meta-Analysis of a Testicular Torsion Risk Score.
Qin KR, Qu LG
J Urol 2022 Jul;208(1):62-70. Epub 2022 Mar 3 doi: 10.1097/JU.0000000000002496. PMID: 35238603
Microsurgical Denervation of the Spermatic Cord: A Historical Perspective and Recent Developments.
Sun HH, Tay KS, Jesse E, Muncey W, Loeb A, Thirumavalavan N
Sex Med Rev 2022 Oct;10(4):791-799. Epub 2022 Jan 5 doi: 10.1016/j.sxmr.2021.11.005. PMID: 34996747
Evaluation and Management of the Adolescent Varicocele.
Kolon TF
J Urol 2015 Nov;194(5):1194-201. Epub 2015 Jun 25 doi: 10.1016/j.juro.2015.06.079. PMID: 26119668

Recent systematic reviews

Diagnosing with a TWIST: Systematic Review and Meta-Analysis of a Testicular Torsion Risk Score.
Qin KR, Qu LG
J Urol 2022 Jul;208(1):62-70. Epub 2022 Mar 3 doi: 10.1097/JU.0000000000002496. PMID: 35238603
Botulinum Toxin-A Injection in Chronic Pelvic Pain Syndrome Treatment: A Systematic Review and Pooled Meta-Analysis.
Panunzio A, Tafuri A, Mazzucato G, Cerrato C, Orlando R, Pagliarulo V, Antonelli A, Cerruto MA
Toxins (Basel) 2022 Jan 1;14(1) doi: 10.3390/toxins14010025. PMID: 35051002Free PMC Article
Evaluation and Management of the Adolescent Varicocele.
Kolon TF
J Urol 2015 Nov;194(5):1194-201. Epub 2015 Jun 25 doi: 10.1016/j.juro.2015.06.079. PMID: 26119668
Scalpel versus no-scalpel incision for vasectomy.
Cook LA, Pun A, Gallo MF, Lopez LM, Van Vliet HA
Cochrane Database Syst Rev 2014 Mar 30;2014(3):CD004112. doi: 10.1002/14651858.CD004112.pub4. PMID: 24683021Free PMC Article
EAU guidelines on chronic pelvic pain.
Fall M, Baranowski AP, Elneil S, Engeler D, Hughes J, Messelink EJ, Oberpenning F, de C Williams AC; European Association of Urology
Eur Urol 2010 Jan;57(1):35-48. Epub 2009 Aug 31 doi: 10.1016/j.eururo.2009.08.020. PMID: 19733958

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