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Vaginal pain

MedGen UID:
65927
•Concept ID:
C0236082
•
Sign or Symptom
Synonyms: Pain in vagina; Vaginal Pain
SNOMED CT: Pain in vagina (38343000); Vaginal pain (38343000)

Definition

A painful sensation in the vagina. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVaginal pain

Professional guidelines

PubMed

Identification and management of adolescent gynecologic emergencies in the emergency department.
Vayngortin T, Kant S
Pediatr Emerg Med Pract 2019 Feb;16(2):1-24. Epub 2019 Feb 1 PMID: 30676713
Guidelines for the Management of a Pregnant Trauma Patient.
Jain V, Chari R, Maslovitz S, Farine D; Maternal Fetal Medicine Committee, Bujold E, Gagnon R, Basso M, Bos H, Brown R, Cooper S, Gouin K, McLeod NL, Menticoglou S, Mundle W, Pylypjuk C, Roggensack A, Sanderson F
J Obstet Gynaecol Can 2015 Jun;37(6):553-74. doi: 10.1016/s1701-2163(15)30232-2. PMID: 26334607
Psychological treatment for vaginal pain: does etiology matter? A systematic review and meta-analysis.
Flanagan E, Herron KA, O'Driscoll C, Williams AC
J Sex Med 2015 Jan;12(1):3-16. Epub 2014 Oct 20 doi: 10.1111/jsm.12717. PMID: 25329756

Recent clinical studies

Etiology

Twisting of transobturator midurethral slings: does it matter?
Gillor M, Dietz HP
Int Urogynecol J 2022 Aug;33(8):2195-2201. Epub 2022 Apr 11 doi: 10.1007/s00192-022-05186-6. PMID: 35403884
Efficacy and safety of a new vaginal gel for the treatment of symptoms associated with vulvovaginal atrophy in postmenopausal women: A double-blind randomized placebo-controlled study.
De Seta F, Caruso S, Di Lorenzo G, Romano F, Mirandola M, Nappi RE
Maturitas 2021 May;147:34-40. Epub 2021 Mar 4 doi: 10.1016/j.maturitas.2021.03.002. PMID: 33832645
Management of complications of mesh surgery.
Lee D, Zimmern PE
Curr Opin Urol 2015 Jul;25(4):284-91. doi: 10.1097/MOU.0000000000000187. PMID: 26049869
Pain following hysterectomy: epidemiological and clinical aspects.
Brandsborg B
Dan Med J 2012 Jan;59(1):B4374. PMID: 22239844
Pain at midlife.
Rousseau ME, Gottlieb SF
J Midwifery Womens Health 2004 Nov-Dec;49(6):529-38. doi: 10.1016/j.jmwh.2004.08.026. PMID: 15544982

Diagnosis

Spontaneous Intracranial and Lumbar Subdural Hematoma Presenting as Vaginal Pain.
Weiner LA, Richardson AC, Tewelde SZ
J Emerg Med 2019 Apr;56(4):e43-e46. Epub 2019 Feb 8 doi: 10.1016/j.jemermed.2018.12.032. PMID: 30745198
Vaginal pH: a simple assessment highly correlated with vaginal morphology and symptoms in postmenopausal women.
Tucker KM, Godha K, Mirkin S, Archer DF
Menopause 2018 Jul;25(7):762-766. doi: 10.1097/GME.0000000000001081. PMID: 29509598
Pathological findings in explanted vaginal mesh.
Li L, Wang X, Park JY, Chen H, Wang Y, Zheng W
Hum Pathol 2017 Nov;69:46-54. Epub 2017 Sep 29 doi: 10.1016/j.humpath.2017.07.020. PMID: 28970142
Management of complications of mesh surgery.
Lee D, Zimmern PE
Curr Opin Urol 2015 Jul;25(4):284-91. doi: 10.1097/MOU.0000000000000187. PMID: 26049869
Psychological treatment for vaginal pain: does etiology matter? A systematic review and meta-analysis.
Flanagan E, Herron KA, O'Driscoll C, Williams AC
J Sex Med 2015 Jan;12(1):3-16. Epub 2014 Oct 20 doi: 10.1111/jsm.12717. PMID: 25329756

Therapy

Twisting of transobturator midurethral slings: does it matter?
Gillor M, Dietz HP
Int Urogynecol J 2022 Aug;33(8):2195-2201. Epub 2022 Apr 11 doi: 10.1007/s00192-022-05186-6. PMID: 35403884
Efficacy and safety of a new vaginal gel for the treatment of symptoms associated with vulvovaginal atrophy in postmenopausal women: A double-blind randomized placebo-controlled study.
De Seta F, Caruso S, Di Lorenzo G, Romano F, Mirandola M, Nappi RE
Maturitas 2021 May;147:34-40. Epub 2021 Mar 4 doi: 10.1016/j.maturitas.2021.03.002. PMID: 33832645
Management of complications of mesh surgery.
Lee D, Zimmern PE
Curr Opin Urol 2015 Jul;25(4):284-91. doi: 10.1097/MOU.0000000000000187. PMID: 26049869
Psychological treatment for vaginal pain: does etiology matter? A systematic review and meta-analysis.
Flanagan E, Herron KA, O'Driscoll C, Williams AC
J Sex Med 2015 Jan;12(1):3-16. Epub 2014 Oct 20 doi: 10.1111/jsm.12717. PMID: 25329756
Pain following hysterectomy: epidemiological and clinical aspects.
Brandsborg B
Dan Med J 2012 Jan;59(1):B4374. PMID: 22239844

Prognosis

Twisting of transobturator midurethral slings: does it matter?
Gillor M, Dietz HP
Int Urogynecol J 2022 Aug;33(8):2195-2201. Epub 2022 Apr 11 doi: 10.1007/s00192-022-05186-6. PMID: 35403884
Clinicopathologic features and outcomes of primary vaginal adenosis as a dermatologic and gynecologic burden: A retrospective study.
Han T, Jin Y, Li Y, Bi Y, Pan L
Medicine (Baltimore) 2018 Dec;97(49):e13470. doi: 10.1097/MD.0000000000013470. PMID: 30544435Free PMC Article
Pathological findings in explanted vaginal mesh.
Li L, Wang X, Park JY, Chen H, Wang Y, Zheng W
Hum Pathol 2017 Nov;69:46-54. Epub 2017 Sep 29 doi: 10.1016/j.humpath.2017.07.020. PMID: 28970142
Management of complications of mesh surgery.
Lee D, Zimmern PE
Curr Opin Urol 2015 Jul;25(4):284-91. doi: 10.1097/MOU.0000000000000187. PMID: 26049869
Pain following hysterectomy: epidemiological and clinical aspects.
Brandsborg B
Dan Med J 2012 Jan;59(1):B4374. PMID: 22239844

Clinical prediction guides

Laser treatment for genitourinary syndrome of menopause: Scientific Impact Paper No. 72 (July 2022): Scientific Impact Paper No. 72 (July 2022).
Phillips C, Hillard T, Salvatore S, Cardozo L, Toozs-Hobson P; Royal College of Obstetricians and Gynaecologists
BJOG 2022 Nov;129(12):e89-e94. Epub 2022 Jul 27 doi: 10.1111/1471-0528.17195. PMID: 35892242
Intrarectal diazepam following pelvic reconstructive surgery: a double-blind, randomized placebo-controlled trial.
Aldrich ER, Tam TY, Saylor LM, Crisp CC, Yeung J, Pauls RN
Am J Obstet Gynecol 2022 Aug;227(2):302.e1-302.e9. Epub 2022 May 10 doi: 10.1016/j.ajog.2022.05.009. PMID: 35550374
Efficacy and safety of a new vaginal gel for the treatment of symptoms associated with vulvovaginal atrophy in postmenopausal women: A double-blind randomized placebo-controlled study.
De Seta F, Caruso S, Di Lorenzo G, Romano F, Mirandola M, Nappi RE
Maturitas 2021 May;147:34-40. Epub 2021 Mar 4 doi: 10.1016/j.maturitas.2021.03.002. PMID: 33832645
Pathological findings in explanted vaginal mesh.
Li L, Wang X, Park JY, Chen H, Wang Y, Zheng W
Hum Pathol 2017 Nov;69:46-54. Epub 2017 Sep 29 doi: 10.1016/j.humpath.2017.07.020. PMID: 28970142
Pain following hysterectomy: epidemiological and clinical aspects.
Brandsborg B
Dan Med J 2012 Jan;59(1):B4374. PMID: 22239844

Recent systematic reviews

Evaluation of the effectiveness and safety of photodynamic therapy in the treatment of precancerous diseases of the cervix (neoplasia) associated with the human papillomavirus: A systematic review.
Shanazarov N, Bariyeva G, Avdeyev A, Albayev R, Kisikova S, Zinchenko S, Galiev I
Photodiagnosis Photodyn Ther 2024 Feb;45:103925. Epub 2023 Dec 7 doi: 10.1016/j.pdpdt.2023.103925. PMID: 38070631
Primary extranodal vaginal non-hodgkin lymphoma: Diagnostic pitfalls and therapeutic challenges.
Petrillo M, Fara AM, Fedeli MA, Fozza C, Cossu A, Gulotta A, Dessole F, Piana A, Capobianco G, Tanda F, Dessole S
Histol Histopathol 2019 Jul;34(7):723-730. Epub 2019 Jan 18 doi: 10.14670/HH-18-085. PMID: 30656635
Psychological treatment for vaginal pain: does etiology matter? A systematic review and meta-analysis.
Flanagan E, Herron KA, O'Driscoll C, Williams AC
J Sex Med 2015 Jan;12(1):3-16. Epub 2014 Oct 20 doi: 10.1111/jsm.12717. PMID: 25329756
Sexual function after transvaginal cholecystectomy: a systematic review.
Donatsky AM, Jørgensen LN, Meisner S, Vilmann P, Rosenberg J
Surg Laparosc Endosc Percutan Tech 2014 Aug;24(4):290-5. doi: 10.1097/SLE.0b013e3182a47a61. PMID: 25077634

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