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Choriocarcinoma of testis

MedGen UID:: 65969
•Concept ID:: C0238449
•: Neoplastic Process

Synonyms:	choriocarcinoma; Choriocarcinoma of Testis; choriocarcinoma of testis; Choriocarcinoma of the Testis; choriocarcinoma of the testis; Testicular Choriocarcinoma; testicular choriocarcinoma; testis choriocarcinoma (disease)

Monarch Initiative:	MONDO:0003508

Definition

A malignant germ cell tumor arising from the testis. It represents the rarest of the testicular germ cell tumors. Histologically it is characterized by the presence of syncytiotrophoblasts and cytotrophoblasts. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVChoriocarcinoma of testis

Phenotypic abnormality
- Abnormality of prenatal development or birth
  - Abnormalities of placenta or umbilical cord
    - Abnormal placenta morphology
      - Choriocarcinoma
        Choriocarcinoma of testis
        Childhood testicular choriocarcinoma
        Stage I Testicular Choriocarcinoma AJCC v6 and v7
        Stage II Testicular Choriocarcinoma AJCC v6 and v7
        Stage III Testicular Choriocarcinoma AJCC v6 and v7
        Testicular monophasic choriocarcinoma

Professional guidelines

PubMed

Current Management of Disseminated Germ Cell Tumors.

Lavoie JM, Kollmannsberger CK
Urol Clin North Am 2019 Aug;46(3):377-388. Epub 2019 May 21 doi: 10.1016/j.ucl.2019.04.003. PMID: 31277732

Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.

Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467

Germinal malignancies of the testis: experience, management and prognosis.

Lindsey CM, Glenn JF
J Urol 1976 Jul;116(1):59-62. doi: 10.1016/s0022-5347(17)58675-9. PMID: 945359

Recent clinical studies

Diagnosis

Cutaneous metastasis of testicular choriocarcinoma, diagnosed by fine-needle aspiration cytology: a rare case report and review of the literature.

Geramizadeh B, Rad H
Indian J Pathol Microbiol 2012 Jul-Sep;55(3):406-8. doi: 10.4103/0377-4929.101760. PMID: 23032847

Pure choriocarcinoma of testis with rare gingival and skin metastases.

Bhatia K, Vaid AK, Rawal S, Patole KD
Singapore Med J 2007 Mar;48(3):e77-80. PMID: 17342276

Prognosis

Rare solitary metastasis to subcutaneous tissue from choriocarcinoma of testis.

Winter CC, Trepashko DW
Urology 1989 Apr;33(4):320-1. doi: 10.1016/0090-4295(89)90276-8. PMID: 2929067

Supplemental Content

Table of contents

Clinical resources

ClinicalTrials.gov

Practice guidelines

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Consumer resources

MedlinePlus

Reviews

Related information

PMC Articles
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