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Gingival recession

MedGen UID:
6607
Concept ID:
C0017572
Finding
Synonyms: Gingival Recession; Gingival Recessions; Recession, Gingival; Recessions, Gingival
SNOMED CT: Gingival soft tissue recession (4356008); Gingival recession (4356008)
 
HPO: HP:0030816
Monarch Initiative: MONDO:0001268

Definition

The loss of gum tissue. The result is that gum tissue is recessed and its position on the tooth is lowered, exposing the roots of the teeth. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGingival recession

Conditions with this feature

Cardiomyopathy, dilated, with wooly hair, keratoderma, and tooth agenesis
MedGen UID:
862830
Concept ID:
C4014393
Disease or Syndrome
Keratoderma with woolly hair is a group of related conditions that affect the skin and hair and in many cases increase the risk of potentially life-threatening heart problems. People with these conditions have hair that is unusually coarse, dry, fine, and tightly curled. In some cases, the hair is also sparse. The woolly hair texture typically affects only scalp hair and is present from birth. Starting early in life, affected individuals also develop palmoplantar keratoderma, a condition that causes skin on the palms of the hands and the soles of the feet to become thick, scaly, and calloused.\n\nCardiomyopathy, which is a disease of the heart muscle, is a life-threatening health problem that can develop in people with keratoderma with woolly hair. Unlike the other features of this condition, signs and symptoms of cardiomyopathy may not appear until adolescence or later. Complications of cardiomyopathy can include an abnormal heartbeat (arrhythmia), heart failure, and sudden death.\n\nKeratoderma with woolly hair comprises several related conditions with overlapping signs and symptoms. Researchers have recently proposed classifying keratoderma with woolly hair into four types, based on the underlying genetic cause. Type I, also known as Naxos disease, is characterized by palmoplantar keratoderma, woolly hair, and a form of cardiomyopathy called arrhythmogenic right ventricular cardiomyopathy (ARVC). Type II, also known as Carvajal syndrome, has hair and skin abnormalities similar to type I but features a different form of cardiomyopathy, called dilated left ventricular cardiomyopathy. Type III also has signs and symptoms similar to those of type I, including ARVC, although the hair and skin abnormalities are often milder. Type IV is characterized by palmoplantar keratoderma and woolly and sparse hair, as well as abnormal fingernails and toenails. Type IV does not appear to cause cardiomyopathy.
Ehlers-Danlos syndrome, periodontal type 2
MedGen UID:
934648
Concept ID:
C4310681
Disease or Syndrome
Periodontal Ehlers-Danlos syndrome (pEDS) is characterized by distinct oral manifestations. Periodontal tissue breakdown beginning in the teens results in premature loss of teeth. Lack of attached gingiva and thin and fragile gums lead to gingival recession. Connective tissue abnormalities of pEDS typically include easy bruising, pretibial plaques, distal joint hypermobility, hoarse voice, and less commonly manifestations such as organ or vessel rupture. Since the first descriptions of pEDS in the 1970s, 148 individuals have been reported in the literature; however, future in-depth descriptions of non-oral manifestations in newly diagnosed individuals with a molecularly confirmed diagnosis of pEDS will be important to further define the clinical features.
Ehlers-Danlos syndrome, periodontal type 1
MedGen UID:
1642148
Concept ID:
C4551499
Disease or Syndrome
Periodontal Ehlers-Danlos syndrome (pEDS) is characterized by distinct oral manifestations. Periodontal tissue breakdown beginning in the teens results in premature loss of teeth. Lack of attached gingiva and thin and fragile gums lead to gingival recession. Connective tissue abnormalities of pEDS typically include easy bruising, pretibial plaques, distal joint hypermobility, hoarse voice, and less commonly manifestations such as organ or vessel rupture. Since the first descriptions of pEDS in the 1970s, 148 individuals have been reported in the literature; however, future in-depth descriptions of non-oral manifestations in newly diagnosed individuals with a molecularly confirmed diagnosis of pEDS will be important to further define the clinical features.
Periodontitis, aggressive 1
MedGen UID:
1644602
Concept ID:
C4551681
Disease or Syndrome
Aggressive periodontitis, which may be generalized or localized, is characterized by severe and protracted gingival infections, leading to tooth loss. Amounts of microbial deposits are generally inconsistent with the severity of periodontal tissue destruction and the progression of attachment and bone loss may be self arresting (American Academy of Periodontology, 2000). The term 'aggressive periodontitis' replaced the terms 'early-onset,' 'prepubertal,' or 'juvenile periodontitis' at a 1999 International workshop for a classification of periodontal disease and conditions, where it was decided that the classification terminology should not be age dependent or require knowledge of rates of progression (Armitage, 1999). Genetic Heterogeneity of Aggressive Periodontitis Aggressive periodontitis-2 (608526) has been mapped to chromosome 1q25.
Polymicrogyria with or without vascular-type Ehlers-Danlos syndrome
MedGen UID:
1675672
Concept ID:
C5193040
Disease or Syndrome
Polymicrogyria with or without vascular-type Ehlers-Danlos syndrome is an autosomal recessive disorder with a highly variable phenotype. Although all patients have polymicrogyria and other variable structural brain anomalies on imaging, only some show developmental delay and/or seizures. Similarly, only some patients have connective tissue defects that particularly affect the vascular system and can result in early death (summary by Vandervore et al., 2017).

Professional guidelines

PubMed

Liu Y, Li CX, Nie J, Mi CB, Li YM
Chin J Dent Res 2023 Mar 29;26(1):11-18. doi: 10.3290/j.cjdr.b3978667. PMID: 36988062
Jepsen K, Sculean A, Jepsen S
Periodontol 2000 2023 Jun;92(1):135-158. Epub 2023 Mar 15 doi: 10.1111/prd.12484. PMID: 36920050
Tavelli L, Barootchi S, Nguyen TVN, Tattan M, Ravidà A, Wang HL
J Periodontol 2018 Sep;89(9):1075-1090. Epub 2018 Aug 13 doi: 10.1002/JPER.18-0066. PMID: 29761502

Recent clinical studies

Etiology

Carcuac O, Trullenque-Eriksson A, Derks J
J Periodontol 2023 Jun;94(6):722-730. Epub 2023 Jan 30 doi: 10.1002/JPER.22-0581. PMID: 36627509
Mehta V, Kaçani G, Moaleem MMA, Almohammadi AA, Alwafi MM, Mulla AK, Alharbi SO, Aljayyar AW, Qeli E, Toti Ç, Meto A, Fiorillo L
Int J Environ Res Public Health 2022 Nov 2;19(21) doi: 10.3390/ijerph192114330. PMID: 36361208Free PMC Article
Cortellini P, Bissada NF
J Periodontol 2018 Jun;89 Suppl 1:S204-S213. doi: 10.1002/JPER.16-0671. PMID: 29926948
Cairo F, Nieri M, Cincinelli S, Mervelt J, Pagliaro U
J Clin Periodontol 2011 Jul;38(7):661-6. Epub 2011 Apr 20 doi: 10.1111/j.1600-051X.2011.01732.x. PMID: 21507033
Kassab MM, Cohen RE
J Am Dent Assoc 2003 Feb;134(2):220-5. doi: 10.14219/jada.archive.2003.0137. PMID: 12636127

Diagnosis

Cortellini P, Bissada NF
J Periodontol 2018 Jun;89 Suppl 1:S204-S213. doi: 10.1002/JPER.16-0671. PMID: 29926948
Fan J, Caton JG
J Periodontol 2018 Jun;89 Suppl 1:S214-S222. doi: 10.1002/JPER.16-0581. PMID: 29926937
Guttiganur N, Aspalli S, Sanikop MV, Desai A, Gaddale R, Devanoorkar A
Indian J Dent Res 2018 Mar-Apr;29(2):233-237. doi: 10.4103/ijdr.IJDR_207_17. PMID: 29652020
Zucchelli G, Mounssif I
Periodontol 2000 2015 Jun;68(1):333-68. doi: 10.1111/prd.12059. PMID: 25867992
Kassab MM, Cohen RE
J Am Dent Assoc 2003 Feb;134(2):220-5. doi: 10.14219/jada.archive.2003.0137. PMID: 12636127

Therapy

Carcuac O, Trullenque-Eriksson A, Derks J
J Periodontol 2023 Jun;94(6):722-730. Epub 2023 Jan 30 doi: 10.1002/JPER.22-0581. PMID: 36627509
Mehta V, Kaçani G, Moaleem MMA, Almohammadi AA, Alwafi MM, Mulla AK, Alharbi SO, Aljayyar AW, Qeli E, Toti Ç, Meto A, Fiorillo L
Int J Environ Res Public Health 2022 Nov 2;19(21) doi: 10.3390/ijerph192114330. PMID: 36361208Free PMC Article
Chambrone L, Salinas Ortega MA, Sukekava F, Rotundo R, Kalemaj Z, Buti J, Pini Prato GP
Cochrane Database Syst Rev 2018 Oct 2;10(10):CD007161. doi: 10.1002/14651858.CD007161.pub3. PMID: 30277568Free PMC Article
Benic GI, Mir-Mari J, Hämmerle CH
Int J Oral Maxillofac Implants 2014;29 Suppl:222-38. doi: 10.11607/jomi.2014suppl.g4.1. PMID: 24660200
Chen ST, Buser D
Int J Oral Maxillofac Implants 2014;29 Suppl:186-215. doi: 10.11607/jomi.2014suppl.g3.3. PMID: 24660198

Prognosis

Carcuac O, Trullenque-Eriksson A, Derks J
J Periodontol 2023 Jun;94(6):722-730. Epub 2023 Jan 30 doi: 10.1002/JPER.22-0581. PMID: 36627509
Agrawal P, Katti N, Mohanty D, Pradhan SS, Raj SC, Satyarup D, Mahopatra A, Srivani P
J Contemp Dent Pract 2022 Jan 1;23(1):49-55. PMID: 35656657
Windisch P, Iorio-Siciliano V, Palkovics D, Ramaglia L, Blasi A, Sculean A
Clin Oral Investig 2022 Feb;26(2):1811-1821. Epub 2021 Sep 7 doi: 10.1007/s00784-021-04155-5. PMID: 34491446Free PMC Article
Rios FS, Costa RSA, Wagner TP, Christofoli BR, Goergen J, Izquierdo C, Jardim JJ, Maltz M, Haas AN
J Clin Periodontol 2021 Jan;48(1):114-125. Epub 2020 Nov 11 doi: 10.1111/jcpe.13383. PMID: 33015887
Cairo F, Nieri M, Cincinelli S, Mervelt J, Pagliaro U
J Clin Periodontol 2011 Jul;38(7):661-6. Epub 2011 Apr 20 doi: 10.1111/j.1600-051X.2011.01732.x. PMID: 21507033

Clinical prediction guides

Imber JC, Kasaj A
Int Dent J 2021 Jun;71(3):178-187. Epub 2021 Jan 29 doi: 10.1111/idj.12617. PMID: 34024328Free PMC Article
Barootchi S, Tavelli L, Zucchelli G, Giannobile WV, Wang HL
J Periodontol 2020 Nov;91(11):1386-1399. Epub 2020 Jun 12 doi: 10.1002/JPER.19-0715. PMID: 32392401
Tavelli L, Barootchi S, Nguyen TVN, Tattan M, Ravidà A, Wang HL
J Periodontol 2018 Sep;89(9):1075-1090. Epub 2018 Aug 13 doi: 10.1002/JPER.18-0066. PMID: 29761502
Zucchelli G, Mounssif I
Periodontol 2000 2015 Jun;68(1):333-68. doi: 10.1111/prd.12059. PMID: 25867992
Cairo F, Nieri M, Cincinelli S, Mervelt J, Pagliaro U
J Clin Periodontol 2011 Jul;38(7):661-6. Epub 2011 Apr 20 doi: 10.1111/j.1600-051X.2011.01732.x. PMID: 21507033

Recent systematic reviews

Mehta V, Kaçani G, Moaleem MMA, Almohammadi AA, Alwafi MM, Mulla AK, Alharbi SO, Aljayyar AW, Qeli E, Toti Ç, Meto A, Fiorillo L
Int J Environ Res Public Health 2022 Nov 2;19(21) doi: 10.3390/ijerph192114330. PMID: 36361208Free PMC Article
Cairo F, Barootchi S, Tavelli L, Barbato L, Wang HL, Rasperini G, Graziani F, Tonetti M
J Clin Periodontol 2020 Nov;47(11):1403-1415. Epub 2020 Sep 9 doi: 10.1111/jcpe.13346. PMID: 32654220
Barootchi S, Tavelli L, Zucchelli G, Giannobile WV, Wang HL
J Periodontol 2020 Nov;91(11):1386-1399. Epub 2020 Jun 12 doi: 10.1002/JPER.19-0715. PMID: 32392401
Tavelli L, Barootchi S, Nguyen TVN, Tattan M, Ravidà A, Wang HL
J Periodontol 2018 Sep;89(9):1075-1090. Epub 2018 Aug 13 doi: 10.1002/JPER.18-0066. PMID: 29761502
Miron RJ, Zucchelli G, Pikos MA, Salama M, Lee S, Guillemette V, Fujioka-Kobayashi M, Bishara M, Zhang Y, Wang HL, Chandad F, Nacopoulos C, Simonpieri A, Aalam AA, Felice P, Sammartino G, Ghanaati S, Hernandez MA, Choukroun J
Clin Oral Investig 2017 Jul;21(6):1913-1927. Epub 2017 May 27 doi: 10.1007/s00784-017-2133-z. PMID: 28551729

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