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Finding of lymph node

MedGen UID:
661956
•Concept ID:
C0578532
•
Finding
Synonyms: Lymph Node Finding; Observation of lymph node
SNOMED CT: Observation of lymph node (301855007); Finding of lymph node (301855007)

Definition

A sign, symptom, or clinical test result related to the lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFinding of lymph node

Professional guidelines

PubMed

A large retrospective multicenter study of vaginal melanomas: implications for new management.
Vaysse C, Pautier P, Filleron T, Maisongrosse V, Rodier JF, Lavoue V, Reyal F, Thomas L, de la Fouchardière A, Delannes M
Melanoma Res 2013 Apr;23(2):138-46. doi: 10.1097/CMR.0b013e32835e590e. PMID: 23449321

Recent clinical studies

Etiology

Lymph node metastases and recurrence in pancreatic neuroendocrine neoplasms.
Nießen A, Schimmack S, Lewosinska M, Hinz U, Bechtiger FA, Hackert T, Büchler MW, Strobel O
Surgery 2022 Dec;172(6):1791-1799. Epub 2022 Sep 28 doi: 10.1016/j.surg.2022.08.020. PMID: 36180252
Extended lymphadenectomy in hilar cholangiocarcinoma: What it will bring?
Li J, Zhou MH, Ma WJ, Li FY, Deng YL
World J Gastroenterol 2020 Jun 28;26(24):3318-3325. doi: 10.3748/wjg.v26.i24.3318. PMID: 32655260Free PMC Article
The Landmark Series: MSLT-1, MSLT-2 and DeCOG (Management of Lymph Nodes).
Bello DM, Faries MB
Ann Surg Oncol 2020 Jan;27(1):15-21. Epub 2019 Sep 18 doi: 10.1245/s10434-019-07830-w. PMID: 31535299
Comprehensive review of vascularized lymph node transfers for lymphedema: Outcomes and complications.
Scaglioni MF, Arvanitakis M, Chen YC, Giovanoli P, Chia-Shen Yang J, Chang EI
Microsurgery 2018 Feb;38(2):222-229. Epub 2016 Jun 7 doi: 10.1002/micr.30079. PMID: 27270748
Mediastinal incidentalomas.
Stigt JA, Boers JE, Oostdijk AH, van den Berg JW, Groen HJ
J Thorac Oncol 2011 Aug;6(8):1345-9. doi: 10.1097/JTO.0b013e31821d41c8. PMID: 21587083

Diagnosis

Lymph Node Dissection: Principles and Postoperative Imaging.
Joyner D, Rizvi T, Kalelioglu T, Jameson MJ, Mukherjee S
Neuroimaging Clin N Am 2022 Feb;32(1):19-36. doi: 10.1016/j.nic.2021.09.001. PMID: 34809838
Prognostic value of lymph node ratio in cancer.
Kar A
Indian J Pathol Microbiol 2019 Apr-Jun;62(2):197-198. doi: 10.4103/IJPM.IJPM_159_19. PMID: 30971539
Lymph node staging in colorectal cancer: old controversies and recent advances.
Resch A, Langner C
World J Gastroenterol 2013 Dec 14;19(46):8515-26. doi: 10.3748/wjg.v19.i46.8515. PMID: 24379568Free PMC Article
Cervical lymph node evaluation and diagnosis.
Bryson TC, Shah GV, Srinivasan A, Mukherji SK
Otolaryngol Clin North Am 2012 Dec;45(6):1363-83. doi: 10.1016/j.otc.2012.08.007. PMID: 23153753
Mediastinal incidentalomas.
Stigt JA, Boers JE, Oostdijk AH, van den Berg JW, Groen HJ
J Thorac Oncol 2011 Aug;6(8):1345-9. doi: 10.1097/JTO.0b013e31821d41c8. PMID: 21587083

Therapy

Sentinel Lymph Node Mapping in Breast Cancer Patients Through Fluorescent Imaging Using Indocyanine Green: The INFLUENCE Trial.
Bargon CA, Huibers A, Young-Afat DA, Jansen BAM, Borel-Rinkes IHM, Lavalaye J, van Slooten HJ, Verkooijen HM, van Swol CFP, Doeksen A
Ann Surg 2022 Nov 1;276(5):913-920. Epub 2022 Jul 27 doi: 10.1097/SLA.0000000000005633. PMID: 35894448
Preservation of Axillary Lymph Nodes Compared with Complete Dissection in T1-2 Breast Cancer Patients Presenting One or Two Metastatic Sentinel Lymph Nodes: The SINODAR-ONE Multicenter Randomized Clinical Trial.
Tinterri C, Gentile D, Gatzemeier W, Sagona A, Barbieri E, Testori A, Errico V, Bottini A, Marrazzo E, Dani C, Dozin B, Boni L, Bruzzi P, Fernandes B, Franceschini D, Spoto R, Torrisi R, Scorsetti M, Santoro A, Canavese G; SINODAR-ONE Collaborative Group
Ann Surg Oncol 2022 Sep;29(9):5732-5744. Epub 2022 May 12 doi: 10.1245/s10434-022-11866-w. PMID: 35552930
Mediastinal staging: when and how?
D'Andrilli A, Maurizi G, Venuta F, Rendina EA
Gen Thorac Cardiovasc Surg 2020 Jul;68(7):725-732. Epub 2019 Dec 3 doi: 10.1007/s11748-019-01263-8. PMID: 31797211
The Landmark Series: MSLT-1, MSLT-2 and DeCOG (Management of Lymph Nodes).
Bello DM, Faries MB
Ann Surg Oncol 2020 Jan;27(1):15-21. Epub 2019 Sep 18 doi: 10.1245/s10434-019-07830-w. PMID: 31535299
Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma.
Faries MB, Thompson JF, Cochran AJ, Andtbacka RH, Mozzillo N, Zager JS, Jahkola T, Bowles TL, Testori A, Beitsch PD, Hoekstra HJ, Moncrieff M, Ingvar C, Wouters MWJM, Sabel MS, Levine EA, Agnese D, Henderson M, Dummer R, Rossi CR, Neves RI, Trocha SD, Wright F, Byrd DR, Matter M, Hsueh E, MacKenzie-Ross A, Johnson DB, Terheyden P, Berger AC, Huston TL, Wayne JD, Smithers BM, Neuman HB, Schneebaum S, Gershenwald JE, Ariyan CE, Desai DC, Jacobs L, McMasters KM, Gesierich A, Hersey P, Bines SD, Kane JM, Barth RJ, McKinnon G, Farma JM, Schultz E, Vidal-Sicart S, Hoefer RA, Lewis JM, Scheri R, Kelley MC, Nieweg OE, Noyes RD, Hoon DSB, Wang HJ, Elashoff DA, Elashoff RM
N Engl J Med 2017 Jun 8;376(23):2211-2222. doi: 10.1056/NEJMoa1613210. PMID: 28591523Free PMC Article

Prognosis

Lymphomas of the head-and-neck region.
Kamiński B
J Cancer Res Ther 2021 Oct-Dec;17(6):1347-1350. doi: 10.4103/jcrt.JCRT_213_20. PMID: 34916364
Prognostic value of lymph node ratio in metastatic papillary thyroid carcinoma.
Mansour J, Sagiv D, Alon E, Talmi Y
J Laryngol Otol 2018 Jan;132(1):8-13. Epub 2017 Nov 10 doi: 10.1017/S0022215117002250. PMID: 29122022
Unusual extramedullary hematopoietic neoplasms in lymph nodes.
Dayton VD, Williams SJ, McKenna RW, Linden MA
Hum Pathol 2017 Apr;62:13-22. Epub 2016 Dec 23 doi: 10.1016/j.humpath.2016.12.014. PMID: 28025076
Status and prognosis of lymph node metastasis in patients with cardia cancer - a systematic review.
Okholm C, Svendsen LB, Achiam MP
Surg Oncol 2014 Sep;23(3):140-6. Epub 2014 Jun 11 doi: 10.1016/j.suronc.2014.06.001. PMID: 24953457
Mediastinal incidentalomas.
Stigt JA, Boers JE, Oostdijk AH, van den Berg JW, Groen HJ
J Thorac Oncol 2011 Aug;6(8):1345-9. doi: 10.1097/JTO.0b013e31821d41c8. PMID: 21587083

Clinical prediction guides

Endosalpingiosis Is Negative for GATA3.
White MJ, Vang R, Argani P, Cimino-Mathews A
Arch Pathol Lab Med 2021 Nov 1;145(11):1448-1452. doi: 10.5858/arpa.2020-0359-OA. PMID: 33571371
Unusual extramedullary hematopoietic neoplasms in lymph nodes.
Dayton VD, Williams SJ, McKenna RW, Linden MA
Hum Pathol 2017 Apr;62:13-22. Epub 2016 Dec 23 doi: 10.1016/j.humpath.2016.12.014. PMID: 28025076
Kikuchi-Fujimoto disease: a clinicopathologic update.
Pepe F, Disma S, Teodoro C, Pepe P, Magro G
Pathologica 2016 Sep;108(3):120-129. PMID: 28195263
Lymph node staging in colorectal cancer: old controversies and recent advances.
Resch A, Langner C
World J Gastroenterol 2013 Dec 14;19(46):8515-26. doi: 10.3748/wjg.v19.i46.8515. PMID: 24379568Free PMC Article
Clinical impact of lymph node status in rectal cancer.
Colombo PE, Patani N, Bibeau F, Assenat E, Bertrand MM, Senesse P, Rouanet P
Surg Oncol 2011 Dec;20(4):e227-33. Epub 2011 Sep 10 doi: 10.1016/j.suronc.2011.08.004. PMID: 21911287

Recent systematic reviews

A systematic review and meta-analysis of vascularized lymph node transfer for breast cancer-related lymphedema.
Winters H, Tielemans HJP, Paulus V, Hummelink S, Slater NJ, Ulrich DJO
J Vasc Surg Venous Lymphat Disord 2022 May;10(3):786-795.e1. Epub 2021 Sep 8 doi: 10.1016/j.jvsv.2021.08.023. PMID: 34508873
Artificial intelligence for pre-operative lymph node staging in colorectal cancer: a systematic review and meta-analysis.
Bedrikovetski S, Dudi-Venkata NN, Kroon HM, Seow W, Vather R, Carneiro G, Moore JW, Sammour T
BMC Cancer 2021 Sep 26;21(1):1058. doi: 10.1186/s12885-021-08773-w. PMID: 34565338Free PMC Article
Axillary Nodal Evaluation in Breast Cancer: State of the Art.
Chang JM, Leung JWT, Moy L, Ha SM, Moon WK
Radiology 2020 Jun;295(3):500-515. Epub 2020 Apr 21 doi: 10.1148/radiol.2020192534. PMID: 32315268
The Benefits and Harms of Different Extents of Lymph Node Dissection During Radical Prostatectomy for Prostate Cancer: A Systematic Review.
Fossati N, Willemse PM, Van den Broeck T, van den Bergh RCN, Yuan CY, Briers E, Bellmunt J, Bolla M, Cornford P, De Santis M, MacPepple E, Henry AM, Mason MD, Matveev VB, van der Poel HG, van der Kwast TH, Rouvière O, Schoots IG, Wiegel T, Lam TB, Mottet N, Joniau S
Eur Urol 2017 Jul;72(1):84-109. Epub 2017 Jan 24 doi: 10.1016/j.eururo.2016.12.003. PMID: 28126351
Idiopathic multicentric Castleman's disease: a systematic literature review.
Liu AY, Nabel CS, Finkelman BS, Ruth JR, Kurzrock R, van Rhee F, Krymskaya VP, Kelleher D, Rubenstein AH, Fajgenbaum DC
Lancet Haematol 2016 Apr;3(4):e163-75. Epub 2016 Mar 17 doi: 10.1016/S2352-3026(16)00006-5. PMID: 27063975

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