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Jessner lymphocytic infiltration of the skin

MedGen UID:
663150
•Concept ID:
C0580181
•
Disease or Syndrome
Synonyms: benign chronic T-cell infiltrative disorder; benign lymphocytic infiltration; Benign lymphocytic infiltration of Jessner; Jessner disease; Jessner's lymphocytic infiltrate; Jessner's lymphocytic infiltration; Jessner's lymphocytic infiltration of skin; Jessner-Kanof lymphocytic infiltration of the skin; Jessner-Kanof syndrome; Jessners lymphocytic infiltrate; lymphocytic infiltrate of Jessner; Lymphocytic Infiltrate of Jessner; Lymphocytic infiltration of Jessner-Kanof
SNOMED CT: Jessner's lymphocytic infiltration (19719003); Lymphocytic infiltration of Jessner-Kanof (19719003); Jessner's lymphocytic infiltrate (19719003); Jessners lymphocytic infiltrate (19719003); Benign lymphocytic infiltration of Jessner (19719003); Jessner's lymphocytic infiltration of skin (19719003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0018051
Orphanet: ORPHA33314

Definition

Jessner lymphocytic infiltration of the skin (JLIS) is a chronic benign cutaneous disease characterized by asymptomatic non-scaly erythematous papules or plaques on the face and neck. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVJessner lymphocytic infiltration of the skin

Professional guidelines

PubMed

The efficacy of pulsed dye laser treatment for inflammatory skin diseases: a systematic review.
Erceg A, de Jong EM, van de Kerkhof PC, Seyger MM
J Am Acad Dermatol 2013 Oct;69(4):609-615.e8. Epub 2013 May 24 doi: 10.1016/j.jaad.2013.03.029. PMID: 23711766
On the differential diagnosis between chronic discoid lupus erythematodes and lymphocytic infiltration of the skin (Jessner), with emphasis on fluorescence microscopy.
ten Have-Opbroek AA
Dermatologica 1966;132(2):109-14. doi: 10.1159/000254409. PMID: 5955977

Recent clinical studies

Etiology

Differentiation of Jessner's Lymphocytic Infiltration of the Skin from Various Chronic Cutaneous Lupus Erythematosus Subtypes by Quantitative Computer-Aided Image Analysis.
Kim IS, Kim BR, Youn SW
Dermatology 2016;232(1):57-63. Epub 2015 Oct 13 doi: 10.1159/000440648. PMID: 26458204
The efficacy of pulsed dye laser treatment for inflammatory skin diseases: a systematic review.
Erceg A, de Jong EM, van de Kerkhof PC, Seyger MM
J Am Acad Dermatol 2013 Oct;69(4):609-615.e8. Epub 2013 May 24 doi: 10.1016/j.jaad.2013.03.029. PMID: 23711766
Lymphocytic infiltration of the skin (Jessner-Kanof) but not reticular erythematous mucinosis occasionally represents clinical manifestations of Borrelia-associated pseudolymphoma.
Ziemer M, Eisendle K, Müller H, Zelger B
Br J Dermatol 2009 Sep;161(3):583-90. Epub 2009 May 26 doi: 10.1111/j.1365-2133.2009.09279.x. PMID: 19486001
The expanding spectrum of cutaneous borreliosis.
Eisendle K, Zelger B
G Ital Dermatol Venereol 2009 Apr;144(2):157-71. PMID: 19357623
The many faces and phases of borreliosis II.
Abele DC, Anders KH
J Am Acad Dermatol 1990 Sep;23(3 Pt 1):401-10. doi: 10.1016/0190-9622(90)70233-8. PMID: 2212138

Diagnosis

Jessner's Lymphocytic Infiltration of the Skin in a 73-Year-Old Woman: A Case Report.
Sánchez CE, Cabezas MDC, Narváez S, Jaramillo H, Miño C
Am J Case Rep 2023 Apr 24;24:e938969. doi: 10.12659/AJCR.938969. PMID: 37088972Free PMC Article
Anti-HMGCR myopathy: clinical and histopathological features, and prognosis.
Kurashige T
Curr Opin Rheumatol 2021 Nov 1;33(6):554-562. doi: 10.1097/BOR.0000000000000832. PMID: 34456255
Etanercept-Induced Lymphocytic Infiltration of Jessner-Kanof.
Abbad N, Lanal T, Brenuchon C, Morel G, Deprez X
Arthritis Rheumatol 2018 Mar;70(3):449. Epub 2018 Jan 10 doi: 10.1002/art.40347. PMID: 29024536
Lymphocytic infiltration of the skin (Jessner-Kanof) but not reticular erythematous mucinosis occasionally represents clinical manifestations of Borrelia-associated pseudolymphoma.
Ziemer M, Eisendle K, Müller H, Zelger B
Br J Dermatol 2009 Sep;161(3):583-90. Epub 2009 May 26 doi: 10.1111/j.1365-2133.2009.09279.x. PMID: 19486001
Immunohistochemical studies in lymphocytic infiltration of the skin (Jessner) and discoid lupus erythematosus. A comparative study.
Willemze R, Vermeer BJ, Meijer CJ
J Am Acad Dermatol 1984 Nov;11(5 Pt 1):832-40. doi: 10.1016/s0190-9622(84)80460-0. PMID: 6392362

Therapy

Cutaneous Pseudolymphoma Due to Hirudotherapy.
Temiz SA, Özer İ, Ataseven A, Dursun R, Fındık S
Turkiye Parazitol Derg 2019 Mar 28;43(1):50-52. doi: 10.4274/tpd.galenos.2018.6037. PMID: 30938141
Lymphoma or pseudolymphoma: A report of six cases and review of the literature.
Tian Z, Shiyu Z, Tao W, Li L, Yuehua L, Hongzhong J
Dermatol Ther 2019 Jul;32(4):e12807. Epub 2019 Jan 7 doi: 10.1111/dth.12807. PMID: 30589489
Etanercept-Induced Lymphocytic Infiltration of Jessner-Kanof.
Abbad N, Lanal T, Brenuchon C, Morel G, Deprez X
Arthritis Rheumatol 2018 Mar;70(3):449. Epub 2018 Jan 10 doi: 10.1002/art.40347. PMID: 29024536
The efficacy of pulsed dye laser treatment for inflammatory skin diseases: a systematic review.
Erceg A, de Jong EM, van de Kerkhof PC, Seyger MM
J Am Acad Dermatol 2013 Oct;69(4):609-615.e8. Epub 2013 May 24 doi: 10.1016/j.jaad.2013.03.029. PMID: 23711766
Innovative uses of thalidomide.
Chen M, Doherty SD, Hsu S
Dermatol Clin 2010 Jul;28(3):577-86. doi: 10.1016/j.det.2010.03.003. PMID: 20510766

Prognosis

Anti-HMGCR myopathy: clinical and histopathological features, and prognosis.
Kurashige T
Curr Opin Rheumatol 2021 Nov 1;33(6):554-562. doi: 10.1097/BOR.0000000000000832. PMID: 34456255
Lymphoma or pseudolymphoma: A report of six cases and review of the literature.
Tian Z, Shiyu Z, Tao W, Li L, Yuehua L, Hongzhong J
Dermatol Ther 2019 Jul;32(4):e12807. Epub 2019 Jan 7 doi: 10.1111/dth.12807. PMID: 30589489
The efficacy of pulsed dye laser treatment for inflammatory skin diseases: a systematic review.
Erceg A, de Jong EM, van de Kerkhof PC, Seyger MM
J Am Acad Dermatol 2013 Oct;69(4):609-615.e8. Epub 2013 May 24 doi: 10.1016/j.jaad.2013.03.029. PMID: 23711766
Could Jessner's lymphocytic infiltrate of the skin be a dermal variant of lupus erythematosus? An analysis of 210 cases.
Lipsker D, Mitschler A, Grosshans E, Cribier B
Dermatology 2006;213(1):15-22. doi: 10.1159/000092832. PMID: 16778421
Granulomatous eccrinotropic lymphomatoid papulosis.
Crowson AN, Baschinsky DY, Kovatich A, Magro C
Am J Clin Pathol 2003 May;119(5):731-9. doi: 10.1309/73DB-A1EP-AWF6-F1T0. PMID: 12760293

Clinical prediction guides

Atypical skin conditions of the neck and back as a dermal manifestation of anti-HMGCR antibody-positive myopathy.
Kurashige T, Nakamura R, Murao T, Mine N, Sato M, Katsumata R, Kanaya Y, Dodo Y, Sugiura T, Ohshita T
BMC Immunol 2024 May 11;25(1):30. doi: 10.1186/s12865-024-00622-2. PMID: 38734636Free PMC Article
Anti-HMGCR myopathy: clinical and histopathological features, and prognosis.
Kurashige T
Curr Opin Rheumatol 2021 Nov 1;33(6):554-562. doi: 10.1097/BOR.0000000000000832. PMID: 34456255
Differentiation of Jessner's Lymphocytic Infiltration of the Skin from Various Chronic Cutaneous Lupus Erythematosus Subtypes by Quantitative Computer-Aided Image Analysis.
Kim IS, Kim BR, Youn SW
Dermatology 2016;232(1):57-63. Epub 2015 Oct 13 doi: 10.1159/000440648. PMID: 26458204
Jessner's lymphocytic infiltration of the skin. A clinical study of 100 patients.
Toonstra J, Wildschut A, Boer J, Smeenk G, Willemze R, van der Putte SC, Boonstra H, van Vloten WA
Arch Dermatol 1989 Nov;125(11):1525-30. PMID: 2684021
Immunohistochemical studies in lymphocytic infiltration of the skin (Jessner) and discoid lupus erythematosus. A comparative study.
Willemze R, Vermeer BJ, Meijer CJ
J Am Acad Dermatol 1984 Nov;11(5 Pt 1):832-40. doi: 10.1016/s0190-9622(84)80460-0. PMID: 6392362

Recent systematic reviews

The efficacy of pulsed dye laser treatment for inflammatory skin diseases: a systematic review.
Erceg A, de Jong EM, van de Kerkhof PC, Seyger MM
J Am Acad Dermatol 2013 Oct;69(4):609-615.e8. Epub 2013 May 24 doi: 10.1016/j.jaad.2013.03.029. PMID: 23711766

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