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Abnormal red blood cell count

MedGen UID:
663423
Concept ID:
C0580548
Finding
Synonyms: Abnormal RBC count; RBC (red blood cell) count abnormal; Red blood cell count abnormal; Red blood cell count outside reference range
SNOMED CT: Red blood cell count abnormal (165427000); Red blood cell count outside reference range (165427000); RBC (red blood cell) count abnormal (165427000)
 
HPO: HP:0020058

Definition

Any deviation from the normal number of red blood cells per volume in the circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal red blood cell count

Professional guidelines

PubMed

Phillips J, Henderson AC
Am Fam Physician 2018 Sep 15;98(6):354-361. PMID: 30215915
Manciu S, Matei E, Trandafir B
Chirurgia (Bucur) 2017 Mar-Apr;112(2):110-116. doi: 10.21614/chirurgia.112.2.110. PMID: 28463670
Zini G, d'Onofrio G, Briggs C, Erber W, Jou JM, Lee SH, McFadden S, Vives-Corrons JL, Yutaka N, Lesesve JF; International Council for Standardization in Haematology (ICSH)
Int J Lab Hematol 2012 Apr;34(2):107-16. Epub 2011 Nov 15 doi: 10.1111/j.1751-553X.2011.01380.x. PMID: 22081912

Recent clinical studies

Etiology

Ajayi S, Becker H, Reinhardt H, Engelhardt M, Zeiser R, von Bubnoff N, Wäsch R
Recent Results Cancer Res 2018;212:119-132. doi: 10.1007/978-3-319-91439-8_6. PMID: 30069628
Manciu S, Matei E, Trandafir B
Chirurgia (Bucur) 2017 Mar-Apr;112(2):110-116. doi: 10.21614/chirurgia.112.2.110. PMID: 28463670
Scully M, Cataland S, Coppo P, de la Rubia J, Friedman KD, Kremer Hovinga J, Lämmle B, Matsumoto M, Pavenski K, Sadler E, Sarode R, Wu H; International Working Group for Thrombotic Thrombocytopenic Purpura
J Thromb Haemost 2017 Feb;15(2):312-322. Epub 2017 Jan 30 doi: 10.1111/jth.13571. PMID: 27868334
Younes M, Dagher GA, Dulanto JV, Njeim M, Kuriakose P
South Med J 2013 Feb;106(2):121-5. doi: 10.1097/SMJ.0b013e3182824cdf. PMID: 23380746
Zini G, d'Onofrio G, Briggs C, Erber W, Jou JM, Lee SH, McFadden S, Vives-Corrons JL, Yutaka N, Lesesve JF; International Council for Standardization in Haematology (ICSH)
Int J Lab Hematol 2012 Apr;34(2):107-16. Epub 2011 Nov 15 doi: 10.1111/j.1751-553X.2011.01380.x. PMID: 22081912

Diagnosis

Phillips J, Henderson AC
Am Fam Physician 2018 Sep 15;98(6):354-361. PMID: 30215915
Manciu S, Matei E, Trandafir B
Chirurgia (Bucur) 2017 Mar-Apr;112(2):110-116. doi: 10.21614/chirurgia.112.2.110. PMID: 28463670
Scully M, Cataland S, Coppo P, de la Rubia J, Friedman KD, Kremer Hovinga J, Lämmle B, Matsumoto M, Pavenski K, Sadler E, Sarode R, Wu H; International Working Group for Thrombotic Thrombocytopenic Purpura
J Thromb Haemost 2017 Feb;15(2):312-322. Epub 2017 Jan 30 doi: 10.1111/jth.13571. PMID: 27868334
Younes M, Dagher GA, Dulanto JV, Njeim M, Kuriakose P
South Med J 2013 Feb;106(2):121-5. doi: 10.1097/SMJ.0b013e3182824cdf. PMID: 23380746
Zini G, d'Onofrio G, Briggs C, Erber W, Jou JM, Lee SH, McFadden S, Vives-Corrons JL, Yutaka N, Lesesve JF; International Council for Standardization in Haematology (ICSH)
Int J Lab Hematol 2012 Apr;34(2):107-16. Epub 2011 Nov 15 doi: 10.1111/j.1751-553X.2011.01380.x. PMID: 22081912

Therapy

Nagalla S, Ballas SK
Cochrane Database Syst Rev 2016 Mar 4;3:CD003426. doi: 10.1002/14651858.CD003426.pub5. PMID: 26942338
Nagalla S, Ballas SK
Cochrane Database Syst Rev 2012 Jul 11;(7):CD003426. doi: 10.1002/14651858.CD003426.pub4. PMID: 22786485
Nagalla S, Ballas SK
Cochrane Database Syst Rev 2010 Jan 20;(1):CD003426. doi: 10.1002/14651858.CD003426.pub3. PMID: 20091545
Singh PC, Ballas SK
Cochrane Database Syst Rev 2007 Oct 17;(4):CD003426. doi: 10.1002/14651858.CD003426.pub2. PMID: 17943791
Riddington C, De Franceschi L
Cochrane Database Syst Rev 2002;(4):CD003426. doi: 10.1002/14651858.CD003426. PMID: 12519597

Prognosis

Read RW, Schlauch KA, Elhanan G, Metcalf WJ, Slonim AD, Aweti R, Borkowski R, Grzymski JJ
PLoS One 2019;14(6):e0218078. Epub 2019 Jun 13 doi: 10.1371/journal.pone.0218078. PMID: 31194788Free PMC Article
Wong WJ, Pozdnyakova O
Int J Lab Hematol 2019 May;41 Suppl 1:142-150. doi: 10.1111/ijlh.13005. PMID: 31069979
Younes M, Dagher GA, Dulanto JV, Njeim M, Kuriakose P
South Med J 2013 Feb;106(2):121-5. doi: 10.1097/SMJ.0b013e3182824cdf. PMID: 23380746
Zini G, d'Onofrio G, Briggs C, Erber W, Jou JM, Lee SH, McFadden S, Vives-Corrons JL, Yutaka N, Lesesve JF; International Council for Standardization in Haematology (ICSH)
Int J Lab Hematol 2012 Apr;34(2):107-16. Epub 2011 Nov 15 doi: 10.1111/j.1751-553X.2011.01380.x. PMID: 22081912
Doll DC, Doll NJ
South Med J 1982 Oct;75(10):1205-10. doi: 10.1097/00007611-198210000-00013. PMID: 7123289

Clinical prediction guides

Nagalla S, Ballas SK
Cochrane Database Syst Rev 2016 Mar 4;3:CD003426. doi: 10.1002/14651858.CD003426.pub5. PMID: 26942338
Lombardi G, Colombini A, Lanteri P, Banfi G
Adv Clin Chem 2013;59:125-53. doi: 10.1016/b978-0-12-405211-6.00005-x. PMID: 23461135
Nagalla S, Ballas SK
Cochrane Database Syst Rev 2012 Jul 11;(7):CD003426. doi: 10.1002/14651858.CD003426.pub4. PMID: 22786485
Zini G, d'Onofrio G, Briggs C, Erber W, Jou JM, Lee SH, McFadden S, Vives-Corrons JL, Yutaka N, Lesesve JF; International Council for Standardization in Haematology (ICSH)
Int J Lab Hematol 2012 Apr;34(2):107-16. Epub 2011 Nov 15 doi: 10.1111/j.1751-553X.2011.01380.x. PMID: 22081912
Grover WH, Bryan AK, Diez-Silva M, Suresh S, Higgins JM, Manalis SR
Proc Natl Acad Sci U S A 2011 Jul 5;108(27):10992-6. Epub 2011 Jun 20 doi: 10.1073/pnas.1104651108. PMID: 21690360Free PMC Article

Recent systematic reviews

Nagalla S, Ballas SK
Cochrane Database Syst Rev 2016 Mar 4;3:CD003426. doi: 10.1002/14651858.CD003426.pub5. PMID: 26942338
Nagalla S, Ballas SK
Cochrane Database Syst Rev 2012 Jul 11;(7):CD003426. doi: 10.1002/14651858.CD003426.pub4. PMID: 22786485
Nagalla S, Ballas SK
Cochrane Database Syst Rev 2010 Jan 20;(1):CD003426. doi: 10.1002/14651858.CD003426.pub3. PMID: 20091545
Singh PC, Ballas SK
Cochrane Database Syst Rev 2007 Oct 17;(4):CD003426. doi: 10.1002/14651858.CD003426.pub2. PMID: 17943791
Riddington C, De Franceschi L
Cochrane Database Syst Rev 2002;(4):CD003426. doi: 10.1002/14651858.CD003426. PMID: 12519597

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