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Multifocal atrial tachycardia

MedGen UID:
66362
Concept ID:
C0221158
Finding
Synonyms: Chaotic atrial tachycardia; chaotic atrial tachycardia; Ectopic atrial tachycardia; MAT; Multifocal Atrial Tachycardia; multifocal atrial tachycardia; multifocal atrial tachycardia (disease); Multifocal Atrial Tachycardia by ECG Finding; Multifocal Atrial Tachycardia by EKG Finding
SNOMED CT: Multifocal atrial tachycardia (49982000)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
HPO: HP:0011701
Monarch Initiative: MONDO:0017988
Orphanet: ORPHA3282

Definition

Multifocal atrial tachycardia is a rare supraventricular arrhythmia in neonates and young infants that is characterized by multiple P waves with varying P wave morphology and is usually asymptomatic. [from HPO]

Term Hierarchy

Conditions with this feature

Cardiomyopathy, dilated, 2G
MedGen UID:
1801983
Concept ID:
C5676995
Disease or Syndrome
Dilated cardiomyopathy-2G (CMD2G) is characterized by early-onset severe dilated cardiomyopathy that progresses rapidly to heart failure in the neonatal period without evidence of intervening hypertrophy. Cardiac tissue exhibits markedly shortened thin filaments, disorganized myofibrils, and reduced contractile force generation, resulting in the severe ventricular dysfunction observed. There is no evidence of skeletal muscle hypertrophy (Ahrens-Nicklas et al., 2019). For a general phenotypic description and a discussion of genetic heterogeneity of dilated cardiomyopathy, see 115200.

Professional guidelines

PubMed

Engel TR, Radhagopalan S
Chest 2000 Jan;117(1):7-8. doi: 10.1378/chest.117.1.7. PMID: 10631189
Schwartz M, Rodman D, Lowenstein SR
J Emerg Med 1994 May-Jun;12(3):353-60. doi: 10.1016/0736-4679(94)90278-x. PMID: 8040593
Scher DL, Arsura EL
Am Heart J 1989 Sep;118(3):574-80. doi: 10.1016/0002-8703(89)90275-5. PMID: 2570520

Recent clinical studies

Etiology

Goudis CA, Konstantinidis AK, Ntalas IV, Korantzopoulos P
Int J Cardiol 2015 Nov 15;199:264-73. Epub 2015 Jul 4 doi: 10.1016/j.ijcard.2015.06.096. PMID: 26218181
Kantoch MJ, Gulamhusein SS, Sanatani S
Can J Cardiol 2011 Jul-Aug;27(4):523.e3-9. Epub 2011 May 28 doi: 10.1016/j.cjca.2010.12.043. PMID: 21621374
Conti VR, Ware DL
Chest Surg Clin N Am 2002 May;12(2):439-60, viii. doi: 10.1016/s1052-3359(02)00006-6. PMID: 12122833
Bradley DJ, Fischbach PS, Law IH, Serwer GA, Dick M 2nd
J Am Coll Cardiol 2001 Aug;38(2):401-8. doi: 10.1016/s0735-1097(01)01390-0. PMID: 11499730
Knight BP, Zivin A, Souza J, Goyal R, Man KC, Strickberger A, Morady F
Am J Med 1998 Oct;105(4):275-80. doi: 10.1016/s0002-9343(98)00261-7. PMID: 9809687

Diagnosis

Conti VR, Ware DL
Chest Surg Clin N Am 2002 May;12(2):439-60, viii. doi: 10.1016/s1052-3359(02)00006-6. PMID: 12122833
Bradley DJ, Fischbach PS, Law IH, Serwer GA, Dick M 2nd
J Am Coll Cardiol 2001 Aug;38(2):401-8. doi: 10.1016/s0735-1097(01)01390-0. PMID: 11499730
McCord J, Borzak S
Chest 1998 Jan;113(1):203-9. doi: 10.1378/chest.113.1.203. PMID: 9440591
Nakazato Y, Nakata Y, Hisaoka T, Sumiyoshi M, Ogura S, Yamaguchi H
Pacing Clin Electrophysiol 1995 Jun;18(6):1244-54. doi: 10.1111/j.1540-8159.1995.tb06964.x. PMID: 7659578
Wang K, Goldfarb BL, Gobel FL, Richman HG
Arch Intern Med 1977 Feb;137(2):161-4. PMID: 836113

Therapy

Oner T, Akdeniz C, Adaletli H
Int J Cardiol 2016 Jan 15;203:855-7. Epub 2015 Oct 30 doi: 10.1016/j.ijcard.2015.10.234. PMID: 26599751
Ueng KC, Lee SH, Wu DJ, Lin CS, Chang MS, Chen SA
Chest 2000 Jan;117(1):52-9. doi: 10.1378/chest.117.1.52. PMID: 10631199
McCord J, Borzak S
Chest 1998 Jan;113(1):203-9. doi: 10.1378/chest.113.1.203. PMID: 9440591
Nademanee K, Singh BN
Ann N Y Acad Sci 1988;522:536-52. doi: 10.1111/j.1749-6632.1988.tb33397.x. PMID: 3288060
Wang K, Goldfarb BL, Gobel FL, Richman HG
Arch Intern Med 1977 Feb;137(2):161-4. PMID: 836113

Prognosis

Goudis CA, Konstantinidis AK, Ntalas IV, Korantzopoulos P
Int J Cardiol 2015 Nov 15;199:264-73. Epub 2015 Jul 4 doi: 10.1016/j.ijcard.2015.06.096. PMID: 26218181
Conti VR, Ware DL
Chest Surg Clin N Am 2002 May;12(2):439-60, viii. doi: 10.1016/s1052-3359(02)00006-6. PMID: 12122833
Bradley DJ, Fischbach PS, Law IH, Serwer GA, Dick M 2nd
J Am Coll Cardiol 2001 Aug;38(2):401-8. doi: 10.1016/s0735-1097(01)01390-0. PMID: 11499730
Nakazato Y, Nakata Y, Hisaoka T, Sumiyoshi M, Ogura S, Yamaguchi H
Pacing Clin Electrophysiol 1995 Jun;18(6):1244-54. doi: 10.1111/j.1540-8159.1995.tb06964.x. PMID: 7659578
Nademanee K, Singh BN
Ann N Y Acad Sci 1988;522:536-52. doi: 10.1111/j.1749-6632.1988.tb33397.x. PMID: 3288060

Clinical prediction guides

Conti VR, Ware DL
Chest Surg Clin N Am 2002 May;12(2):439-60, viii. doi: 10.1016/s1052-3359(02)00006-6. PMID: 12122833
Nademanee K, Singh BN
Ann N Y Acad Sci 1988;522:536-52. doi: 10.1111/j.1749-6632.1988.tb33397.x. PMID: 3288060
Kobayashi Y, Yazawa T, Baba T, Mukai H, Inoue S, Takeyama Y, Niitani H
Pacing Clin Electrophysiol 1988 Aug;11(8):1154-67. doi: 10.1111/j.1540-8159.1988.tb03967.x. PMID: 2459668
Singh BN, Nademanee K
Am J Cardiol 1987 Jan 30;59(3):153B-162B. doi: 10.1016/0002-9149(87)90096-8. PMID: 2433930
Wang K, Goldfarb BL, Gobel FL, Richman HG
Arch Intern Med 1977 Feb;137(2):161-4. PMID: 836113

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