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reflux

MedGen UID:
66675
Concept ID:
C0232483
Pathologic Function
Synonym: Reflux

Definition

An abnormal backward flow of a body fluid. [from NCI]

Professional guidelines

PubMed

Yadlapati R, Gyawali CP, Pandolfino JE; CGIT GERD Consensus Conference Participants
Clin Gastroenterol Hepatol 2022 May;20(5):984-994.e1. Epub 2022 Feb 2 doi: 10.1016/j.cgh.2022.01.025. PMID: 35123084Free PMC Article
Katz PO, Dunbar KB, Schnoll-Sussman FH, Greer KB, Yadlapati R, Spechler SJ
Am J Gastroenterol 2022 Jan 1;117(1):27-56. doi: 10.14309/ajg.0000000000001538. PMID: 34807007Free PMC Article
Chen J, Brady P
Gastroenterol Nurs 2019 Jan/Feb;42(1):20-28. doi: 10.1097/SGA.0000000000000359. PMID: 30688703

Recent clinical studies

Etiology

Chen JW, Vela MF, Peterson KA, Carlson DA
Clin Gastroenterol Hepatol 2023 Jun;21(6):1414-1421.e3. Epub 2023 Apr 14 doi: 10.1016/j.cgh.2023.01.040. PMID: 37061897
Cheng J, Ouwehand AC
Nutrients 2020 Jan 2;12(1) doi: 10.3390/nu12010132. PMID: 31906573Free PMC Article
Eichenwald EC; COMMITTEE ON FETUS AND NEWBORN
Pediatrics 2018 Jul;142(1) Epub 2018 Jun 18 doi: 10.1542/peds.2018-1061. PMID: 29915158
Mungan Z, Pınarbaşı Şimşek B
Turk J Gastroenterol 2017 Dec;28(Suppl 1):S38-S43. doi: 10.5152/tjg.2017.11. PMID: 29199166
Dağlı Ü, Kalkan İH
Turk J Gastroenterol 2017 Dec;28(Suppl 1):S33-S37. doi: 10.5152/tjg.2017.10. PMID: 29199165

Diagnosis

Krause AJ, Walsh EH, Weissbrod PA, Taft TH, Yadlapati R
Ann N Y Acad Sci 2022 Apr;1510(1):5-17. Epub 2021 Dec 17 doi: 10.1111/nyas.14728. PMID: 34921412Free PMC Article
Maret-Ouda J, Markar SR, Lagergren J
JAMA 2020 Dec 22;324(24):2565. doi: 10.1001/jama.2020.21573. PMID: 33351044
Young A, Kumar MA, Thota PN
Cleve Clin J Med 2020 Apr;87(4):223-230. doi: 10.3949/ccjm.87a.19114. PMID: 32238378
Chabra S, Peeples ES
Pediatr Ann 2020 Feb 1;49(2):e77-e81. doi: 10.3928/19382359-20200121-02. PMID: 32045486
Villa N, Vela MF
Gastroenterol Clin North Am 2013 Mar;42(1):17-26. doi: 10.1016/j.gtc.2012.11.003. PMID: 23452628

Therapy

Thurber KM, Otto AO, Stricker SL
Am J Health Syst Pharm 2023 Apr 8;80(8):487-494. doi: 10.1093/ajhp/zxad009. PMID: 36629265
Rebelo F, Mansur IR, Miglioli TC, Meio MDB, Junior SCG
PLoS One 2022;17(7):e0271993. Epub 2022 Jul 22 doi: 10.1371/journal.pone.0271993. PMID: 35867728Free PMC Article
Qiu K, Wang J, Chen B, Wang H, Ma C
Ann Palliat Med 2020 Mar;9(2):405-413. Epub 2020 Mar 17 doi: 10.21037/apm.2020.02.35. PMID: 32233626
Graham DY, Tansel A
Clin Gastroenterol Hepatol 2018 Jun;16(6):800-808.e7. Epub 2017 Sep 28 doi: 10.1016/j.cgh.2017.09.033. PMID: 28964908Free PMC Article
Brady M, Kinn S, Stuart P
Cochrane Database Syst Rev 2003;(4):CD004423. doi: 10.1002/14651858.CD004423. PMID: 14584013

Prognosis

Zhang D, Liu S, Li Z, Wang R
Ann Med 2022 Dec;54(1):1372-1384. doi: 10.1080/07853890.2022.2074535. PMID: 35579516Free PMC Article
Zheng Z, Shang Y, Wang N, Liu X, Xin C, Yan X, Zhai Y, Yin J, Zhang J, Zhang Z
Int J Biol Sci 2021;17(15):4154-4164. Epub 2021 Oct 3 doi: 10.7150/ijbs.65066. PMID: 34803489Free PMC Article
DiSiena M, Perelman A, Birk J, Rezaizadeh H
South Med J 2021 Mar;114(3):161-168. doi: 10.14423/SMJ.0000000000001226. PMID: 33655310
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article
Hodges SJ, Werle D, McLorie G, Atala A
ScientificWorldJournal 2010 Apr 13;10:603-12. doi: 10.1100/tsw.2010.54. PMID: 20419273Free PMC Article

Clinical prediction guides

Zhang C, Liu Z, Zhang J, Wang X, Wang J, Zhao J, Li J, Liu L
Laryngoscope 2023 Sep;133(9):2104-2109. Epub 2022 Dec 1 doi: 10.1002/lary.30489. PMID: 36453478
Khoma O, Burton L, Falk MG, Van der Wall H, Falk GL
Esophagus 2020 Jul;17(3):355-362. Epub 2020 Feb 21 doi: 10.1007/s10388-020-00726-9. PMID: 32086701
Stachler RJ, Dworkin-Valenti JP
Curr Opin Otolaryngol Head Neck Surg 2017 Jun;25(3):242-246. doi: 10.1097/MOO.0000000000000354. PMID: 28266945
Rosen R, Mitchell PD, Amirault J, Amin M, Watters K, Rahbar R
J Pediatr 2017 Apr;183:127-131. Epub 2016 Dec 13 doi: 10.1016/j.jpeds.2016.11.035. PMID: 27979581Free PMC Article
Malgor RD, Labropoulos N
Phlebology 2013 Mar;28 Suppl 1:51-4. doi: 10.1177/0268355513476637. PMID: 23482535

Recent systematic reviews

Zdrhova L, Bitnar P, Balihar K, Kolar P, Madle K, Martinek M, Pandolfino JE, Martinek J
Dysphagia 2023 Apr;38(2):609-621. Epub 2022 Jul 16 doi: 10.1007/s00455-022-10494-6. PMID: 35842548Free PMC Article
Cheng J, Ouwehand AC
Nutrients 2020 Jan 2;12(1) doi: 10.3390/nu12010132. PMID: 31906573Free PMC Article
Eusebi LH, Ratnakumaran R, Yuan Y, Solaymani-Dodaran M, Bazzoli F, Ford AC
Gut 2018 Mar;67(3):430-440. Epub 2017 Feb 23 doi: 10.1136/gutjnl-2016-313589. PMID: 28232473
Mungan Z, Pınarbaşı Şimşek B
Turk J Gastroenterol 2017 Dec;28(Suppl 1):S38-S43. doi: 10.5152/tjg.2017.11. PMID: 29199166
Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R; Global Consensus Group
Am J Gastroenterol 2006 Aug;101(8):1900-20; quiz 1943. doi: 10.1111/j.1572-0241.2006.00630.x. PMID: 16928254

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